DK241883A - Fremgangsmaade til fremstilling af 1-sulfo-2-oxoazetidinderivater - Google Patents

Fremgangsmaade til fremstilling af 1-sulfo-2-oxoazetidinderivater Download PDF

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Publication number
DK241883A
DK241883A DK241883A DK241883A DK241883A DK 241883 A DK241883 A DK 241883A DK 241883 A DK241883 A DK 241883A DK 241883 A DK241883 A DK 241883A DK 241883 A DK241883 A DK 241883A
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DK
Denmark
Prior art keywords
oxoazetide
sulfo
derivatives
procedure
preparation
Prior art date
Application number
DK241883A
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English (en)
Other versions
DK241883D0 (da
Inventor
Andre Furlenmeier
Werner Hofheinz
Christian Nicolas Hubschwerlen
Hans Peter Isenring
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of DK241883D0 publication Critical patent/DK241883D0/da
Publication of DK241883A publication Critical patent/DK241883A/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D205/00Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C07D205/085Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a nitrogen atom directly attached in position 3
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/34Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/48Nitrogen atoms not forming part of a nitro radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/0803Compounds with Si-C or Si-Si linkages
    • C07F7/081Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
    • C07F7/0812Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te comprising a heterocyclic ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK241883A 1982-06-03 1983-05-27 Fremgangsmaade til fremstilling af 1-sulfo-2-oxoazetidinderivater DK241883A (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CH341782 1982-06-03
CH341682 1982-06-03
CH220183 1983-04-25

Publications (2)

Publication Number Publication Date
DK241883D0 DK241883D0 (da) 1983-05-27
DK241883A true DK241883A (da) 1983-12-04

Family

ID=27173519

Family Applications (1)

Application Number Title Priority Date Filing Date
DK241883A DK241883A (da) 1982-06-03 1983-05-27 Fremgangsmaade til fremstilling af 1-sulfo-2-oxoazetidinderivater

Country Status (14)

Country Link
EP (1) EP0096297B1 (da)
AU (1) AU558593B2 (da)
DE (1) DE3377061D1 (da)
DK (1) DK241883A (da)
ES (2) ES8504120A1 (da)
FI (1) FI832004L (da)
GR (1) GR78269B (da)
IE (1) IE55402B1 (da)
IL (1) IL68817A (da)
MC (1) MC1527A1 (da)
NO (1) NO832001L (da)
NZ (1) NZ204386A (da)
PH (2) PH18877A (da)
PT (1) PT76809A (da)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MA19602A1 (fr) * 1981-09-30 1983-04-01 Ciba Geigy Ag Composes d'amino-oxazolyle, procede pour leur preparation, preparations pharmaceutiques qui contiennent ces composes, et leur application
AU564150B2 (en) * 1982-04-30 1987-08-06 Takeda Chemical Industries Ltd. 1-sulfo-2-azetidinone derivatives
CA1263399A (en) * 1984-12-19 1989-11-28 Hoffmann-La Roche Limited Process for the manufacture of aminothiazole acetic acid derivatives
US4883869A (en) * 1984-12-20 1989-11-28 The Upjohn Company Novel beta-lactams containing amino acid substituents
US4837318A (en) * 1985-05-09 1989-06-06 The Upjohn Company Carbonate substituted monobactams as antibiotics
JPS62502825A (ja) * 1985-05-09 1987-11-12 ジ・アップジョン・カンパニ− 抗生物質としてのカ−ボネ−ト置換モノバクタム
US4675398A (en) * 1985-08-16 1987-06-23 E. R. Squibb & Sons, Inc. Copper-mediated oximation reaction
US4684722A (en) * 1986-01-06 1987-08-04 E. R. Squibb & Sons, Inc. Monosulfactams
YU44630B (en) * 1987-06-11 1990-10-31 Krka Process for preparing 6-/d(-)-alpha(4-ethyl-2,3-dioxo-1-piperazincarboxamido)-phenylacetamido/phenicilanic acid
US5015737A (en) * 1987-07-22 1991-05-14 The Upjohn Company Therapeutically useful beta-lactams
WO1992007840A1 (en) * 1990-11-02 1992-05-14 Taisho Pharmaceutical Co., Ltd. Thiazole thioester derivative
AT402928B (de) * 1994-12-23 1997-09-25 Biochemie Gmbh Neues verfahren zur herstellung von cefotaxim
AT406773B (de) * 1998-04-02 2000-08-25 Biochemie Gmbh Neues salz von 7-(2-(aminothiazol-4yl)-2-
CN102083805A (zh) * 2008-07-24 2011-06-01 弗·哈夫曼-拉罗切有限公司 4,5-二氢-唑-2-基衍生物
US8242153B2 (en) 2008-07-24 2012-08-14 Hoffmann-La Roche Inc. 4,5-dihydro-oxazol-2YL derivatives
SI3122745T1 (sl) 2014-03-24 2019-05-31 Novartis Ag Organske spojine monobaktama za zdravljenje bakterijskih infekcij
SI3353175T1 (sl) 2015-09-23 2020-11-30 Novartis Ag Soli in trdne oblike monobaktam antibiotika
CA3063649A1 (en) 2017-08-02 2019-02-07 Novartis Ag Chemical process for manufacturing monobactam antibiotic and intermediates thereof

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0009008A3 (de) * 1978-09-08 1980-05-14 Ciba-Geigy Ag Cephalosporinderivate, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Präparate
EP0021678B1 (en) * 1979-06-08 1984-11-07 Takeda Chemical Industries, Ltd. 1-sulpho-2-oxoazetidine derivatives, their production and pharmaceutical compositions thereof
NZ205240A (en) * 1980-02-07 1984-07-31 Squibb & Sons Inc Sulphonamide derivatives,being starting materials for producing beta-lactams
CY1365A (en) * 1980-03-28 1987-08-07 Biochemie Gmbh New process for the production of cephalosporin antibiotics, and novel intermediates used in such process and their production
WO1982001873A1 (en) * 1980-12-05 1982-06-10 Takeda Chemical Industries Ltd 1-sulfo-2-oxoazetidine derivatives and process for their preparation
EP0059683A3 (de) * 1981-02-27 1982-12-01 Ciba-Geigy Ag 7-Acylamido-3-cephem-4-carbonsäureverbindungen, Verfahren zu ihrer Herstellung, pharmazeutische Präparate, welche diese Verbindungen enthalten, und Verwendung von letzteren
EP0075104A3 (de) * 1981-09-23 1984-11-28 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Cephalosporinderivate, Verfahren zu deren Herstellung und Zwischenprodukte dafür sowie entsprechende pharmazeutische Präparate
MA19602A1 (fr) * 1981-09-30 1983-04-01 Ciba Geigy Ag Composes d'amino-oxazolyle, procede pour leur preparation, preparations pharmaceutiques qui contiennent ces composes, et leur application
US4379787A (en) * 1981-10-02 1983-04-12 Eli Lilly And Company Oximino-substituted cephalosporin compounds
FR2515182B1 (fr) * 1981-10-23 1986-05-09 Roussel Uclaf Nouveaux produits derives de l'acide 3-amino 2-oxo azetidine 1-sulfamique, leur procede de preparation, leur application comme medicaments et les produits intermediaires necessaires a leur preparation

Also Published As

Publication number Publication date
ES8601123A1 (es) 1985-11-01
EP0096297A3 (en) 1984-04-11
DK241883D0 (da) 1983-05-27
FI832004L (fi) 1983-12-04
FI832004A0 (fi) 1983-06-03
IL68817A (en) 1989-08-15
PT76809A (en) 1983-07-01
EP0096297B1 (de) 1988-06-15
PH18877A (en) 1985-10-22
ES522886A0 (es) 1985-04-16
IE831305L (en) 1983-12-05
ES529774A0 (es) 1985-11-01
PH21897A (en) 1988-04-07
GR78269B (da) 1984-09-26
AU1506883A (en) 1983-12-15
AU558593B2 (en) 1987-02-05
IE55402B1 (en) 1990-09-12
IL68817A0 (en) 1983-09-30
NO832001L (no) 1983-12-05
DE3377061D1 (en) 1988-07-21
EP0096297A2 (de) 1983-12-21
MC1527A1 (fr) 1984-04-13
ES8504120A1 (es) 1985-04-16
NZ204386A (en) 1986-12-05

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment
AHB Application shelved due to non-payment