DK2392343T3 - Antimikrobielle sammensætninger, der omfatter hypohalit og/eller hypothiocyanit og anvendelser deraf - Google Patents

Antimikrobielle sammensætninger, der omfatter hypohalit og/eller hypothiocyanit og anvendelser deraf Download PDF

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Publication number
DK2392343T3
DK2392343T3 DK11177009.5T DK11177009T DK2392343T3 DK 2392343 T3 DK2392343 T3 DK 2392343T3 DK 11177009 T DK11177009 T DK 11177009T DK 2392343 T3 DK2392343 T3 DK 2392343T3
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composition
lactoferrin
combination
growth factor
hypothiocyanite
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DK11177009.5T
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English (en)
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Jean-Paul Perraudin
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Perraudin Jean Paul
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Priority claimed from US11/480,676 external-priority patent/US20070116698A1/en
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/40—Transferrins, e.g. lactoferrins, ovotransferrins
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N59/00—Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N59/00—Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds
    • A01N59/12—Iodine, e.g. iodophors; Compounds thereof
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N59/00—Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds
    • A01N59/24—Cyanogen or compounds thereof, e.g. hydrogen cyanide, cyanic acid, cyanamide, thiocyanic acid
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N61/00—Biocides, pest repellants or attractants, or plant growth regulators containing substances of unknown or undetermined composition, e.g. substances characterised only by the mode of action
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N63/00—Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N63/00—Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
    • A01N63/50—Isolated enzymes; Isolated proteins
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    • A61K31/075—Ethers or acetals
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    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
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Claims (17)

1. Sammensætning, der omfatter: mindst én ion valgt fra hypohalit, hypothiocyanit eller en kombination deraf og mindst én forbindelse valgt fra lactoferrin, lactoferrinpeptid frembragt ved indvirkningen af en protease eller en kombination af proteaser på lactoferrin, lysozym eller en kombination deraf; hvor hypohalitten og/eller hypothiocyanitionen er isoleret og ikke i kombination med peroxidasesystemet.
2. Sammensætning ifølge krav 1, der endvidere omfatter immunoglobuliner.
3. Sammensætning ifølge krav 1 eller 2, hvor ionen er hypothiocyanit.
4. Sammensætning ifølge krav 1 eller 2, hvor ionen er hypohalit.
5. Sammensætning ifølge krav 4, hvor ionhypohalitten er valgt fra gruppen bestående af hypochlorit, hypoiodit, hypobromit eller en kombination deraf.
6. Sammensætning ifølge et hvilket som helst af kravene 1 til 5, hvor den mindst ene forbindelse er lactoferrin.
7. Sammensætning ifølge et hvilket som helst af kravene 1 til 6, der endvidere omfatter en vækstfaktor.
8. Sammensætning ifølge krav 7, hvor vækstfaktoren er valgt fra blodpladeafledt vækstfaktor, fibroblastvækstfaktor, transformerende vækstfaktor, angiogenin, epidermal vækstfaktor eller en kombination deraf.
9. Sammensætning ifølge krav 7 eller 8, hvor sammensætningen omfatter valle-colostrum og/eller colostrum som en kilde til den mindst ene vækstfaktor.
10. Sammensætning ifølge krav 3, hvor hypothiocyanitten er i en koncentration i intervallet fra 0,1 pM til 5000 pM.
11. Sammensætning ifølge et hvilket som helst af kravene 4 til 5, hvor hypohalitten er i en koncentration i intervallet fra 0,1 μΜ til 5000 μΜ.
12. Sammensætning ifølge krav 6, hvor lactoferrin er i en koncentration i intervallet fra 0,1 μg til 5000 mg/L.
13. Medikament, der omfatter sammensætningen ifølge et hvilket som helst af kravene 1 til 12.
14. Sammensætning ifølge et hvilket som helst af kravene 1 til 12 til anvendelse i profylaksen og/eller terapien af sygdomme forårsaget af mikroorganismer, hvor mikroorganismerne er valgt fra gruppen bestående af bakterier og svampe.
15. Ikke-medicinsk anvendelse af sammensætning ifølge et hvilket som helst af kravene 1 til 12 til forebyggelse, hæmning eller destruktion af mikroorganismer organiseret som biofilm.
16. Sammensætning ifølge et hvilket som helst af kravene 1 til 12 til anvendelse i forebyggelse eller behandling af sygdomme relateret til svampe eller bakterier og valgt fra gruppen bestående af gastrointestinale infektioner, calculus og forekomst af caries, gingivitis, mucositis, periodontale sygdomme, vaginale sygdomme, acne, ulcer, rejsediarré, cystitis eller chlamydiainfektioner.
17. Sammensætning ifølge et hvilket som helst af kravene 1 til 12 til anvendelse i profylaksen og/eller terapien af sygdomme forårsaget af Helicobacter pylori.
DK11177009.5T 2006-07-03 2007-07-03 Antimikrobielle sammensætninger, der omfatter hypohalit og/eller hypothiocyanit og anvendelser deraf DK2392343T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11/480,676 US20070116698A1 (en) 1999-07-07 2006-07-03 Novel methods and medicament for treating infectious diseases involving microbial biofilms
EP2006006452 2006-07-03
EP07765770A EP2081588A1 (en) 2006-07-03 2007-07-03 Antimicrobial composition and uses thereof

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DK2392343T3 true DK2392343T3 (da) 2019-01-28

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Country Link
US (2) US8263138B2 (da)
EP (1) EP2081588A1 (da)
CN (2) CN101528253A (da)
DK (1) DK2392343T3 (da)
ES (1) ES2704454T3 (da)
TR (1) TR201900010T4 (da)
WO (1) WO2008003688A1 (da)

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US20130064809A1 (en) 2013-03-14
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US8263138B2 (en) 2012-09-11
US20090317378A1 (en) 2009-12-24
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TR201900010T4 (tr) 2019-02-21
EP2081588A1 (en) 2009-07-29
US9555081B2 (en) 2017-01-31

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