DK230580A - Sisomicinderivater fremgangsmaade til fremstilling heraf samt deres anvendelse som laegemiddel - Google Patents

Sisomicinderivater fremgangsmaade til fremstilling heraf samt deres anvendelse som laegemiddel

Info

Publication number
DK230580A
DK230580A DK230580A DK230580A DK230580A DK 230580 A DK230580 A DK 230580A DK 230580 A DK230580 A DK 230580A DK 230580 A DK230580 A DK 230580A DK 230580 A DK230580 A DK 230580A
Authority
DK
Denmark
Prior art keywords
preparing
medicine
derivatives
sisomicin derivatives
derivatives procedure
Prior art date
Application number
DK230580A
Other languages
English (en)
Inventor
U Petersen
K G Metzger
H J Zeiler
P Stadler
E Voss
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of DK230580A publication Critical patent/DK230580A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
    • C07H15/234—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2
    • C07H15/236—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2 a saccharide radical being substituted by an alkylamino radical in position 3 and by two substituents different from hydrogen in position 4, e.g. gentamicin complex, sisomicin, verdamycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Peptides Or Proteins (AREA)
DK230580A 1979-05-30 1980-05-28 Sisomicinderivater fremgangsmaade til fremstilling heraf samt deres anvendelse som laegemiddel DK230580A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19792921973 DE2921973A1 (de) 1979-05-30 1979-05-30 Sisomicin-derivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel

Publications (1)

Publication Number Publication Date
DK230580A true DK230580A (da) 1980-12-01

Family

ID=6072057

Family Applications (1)

Application Number Title Priority Date Filing Date
DK230580A DK230580A (da) 1979-05-30 1980-05-28 Sisomicinderivater fremgangsmaade til fremstilling heraf samt deres anvendelse som laegemiddel

Country Status (8)

Country Link
US (1) US4312859A (da)
EP (1) EP0019843B1 (da)
JP (1) JPS55160791A (da)
AT (1) ATE1609T1 (da)
CA (1) CA1141759A (da)
DE (2) DE2921973A1 (da)
DK (1) DK230580A (da)
ES (1) ES491960A0 (da)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3101376A1 (de) * 1981-01-17 1982-09-02 Bayer Ag, 5090 Leverkusen Sisomicin-derivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
US5079234A (en) * 1989-03-23 1992-01-07 Bristol-Myers Squibb Co. Inhibitors of aminoglycoside nephrotoxicity
US7794713B2 (en) * 2004-04-07 2010-09-14 Lpath, Inc. Compositions and methods for the treatment and prevention of hyperproliferative diseases
US20090074720A1 (en) * 2005-10-28 2009-03-19 Sabbadini Roger A Methods for decreasing immune response and treating immune conditions
US20080213274A1 (en) * 2005-10-28 2008-09-04 Sabbadini Roger A Compositions and methods for the treatment and prevention of fibrotic, inflammatory, and neovascularization conditions of the eye
US7862812B2 (en) * 2006-05-31 2011-01-04 Lpath, Inc. Methods for decreasing immune response and treating immune conditions
CA2706369C (en) * 2007-11-21 2014-03-25 Achaogen, Inc. Antibacterial aminoglycoside analogs
WO2010132760A1 (en) 2009-05-15 2010-11-18 Achaogen, Inc. Antibacterial derivatives of tobramycin
WO2010132768A1 (en) 2009-05-15 2010-11-18 Achaogen, Inc. Antibacterial derivatives of sisomicin
WO2010132757A2 (en) 2009-05-15 2010-11-18 Achaogen, Inc. Antibacterial aminoglycoside analogs
WO2010132759A1 (en) 2009-05-15 2010-11-18 Achaogen, Inc. Antibacterial derivatives of dibekacin
WO2010132765A2 (en) 2009-05-15 2010-11-18 Achaogen, Inc. Antibacterial aminoglycoside analogs

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5324415B2 (da) * 1972-10-06 1978-07-20
US3965089A (en) * 1973-03-12 1976-06-22 Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai Process for the production of a cyclic ureido-derivative of a deoxystreptamine-containing antibiotic and products thereof
PH12960A (en) * 1974-03-19 1979-10-19 Scherico Ltd Derivatives of 4,6-di-(aminoglycosyl)-1,3-diaminocy-clitols and pharmaceutical compositions thereof
AR207582A1 (es) * 1974-03-19 1976-10-15 Scherico Ltd Procedimiento para preparar derivados de diaminociclitole
JPS51127045A (en) * 1975-04-24 1976-11-05 Microbial Chem Res Found A process for preparing 3'- deoxykanamycin a derivatives.
DE2832268A1 (de) * 1978-07-22 1980-01-31 Bayer Ag Pseudotrisaccharide

Also Published As

Publication number Publication date
CA1141759A (en) 1983-02-22
EP0019843B1 (de) 1982-09-29
EP0019843A1 (de) 1980-12-10
ATE1609T1 (de) 1982-10-15
US4312859A (en) 1982-01-26
ES8102147A1 (es) 1980-12-16
DE2921973A1 (de) 1980-12-11
ES491960A0 (es) 1980-12-16
JPS55160791A (en) 1980-12-13
DE3060897D1 (en) 1982-11-11

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