DK2256500T3 - Anvendelse af inhibitorer af enzymet TKTL1 - Google Patents
Anvendelse af inhibitorer af enzymet TKTL1Info
- Publication number
- DK2256500T3 DK2256500T3 DK10009323.6T DK10009323T DK2256500T3 DK 2256500 T3 DK2256500 T3 DK 2256500T3 DK 10009323 T DK10009323 T DK 10009323T DK 2256500 T3 DK2256500 T3 DK 2256500T3
- Authority
- DK
- Denmark
- Prior art keywords
- agf
- mam
- individual
- patient
- tktl1
- Prior art date
Links
- 101000800498 Homo sapiens Transketolase-like protein 1 Proteins 0.000 title abstract 3
- 102100033108 Transketolase-like protein 1 Human genes 0.000 title abstract 3
- 239000003112 inhibitor Substances 0.000 title abstract 2
- 238000000034 method Methods 0.000 abstract 3
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 abstract 1
- 239000012190 activator Substances 0.000 abstract 1
- 239000012472 biological sample Substances 0.000 abstract 1
- 230000004151 fermentation Effects 0.000 abstract 1
- 238000000855 fermentation Methods 0.000 abstract 1
- 239000008103 glucose Substances 0.000 abstract 1
- 230000037353 metabolic pathway Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/54—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving glucose or galactose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/48—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Diabetes (AREA)
- Microbiology (AREA)
- Genetics & Genomics (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Emergency Medicine (AREA)
- Neurology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Endocrinology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Dermatology (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP05004930A EP1701165A1 (en) | 2005-03-07 | 2005-03-07 | Therapeutic and diagnostic uses of TKTL1 and inhibitors and activators thereof |
EP05013170 | 2005-06-17 | ||
EP06723195A EP1856537B1 (en) | 2005-03-07 | 2006-03-03 | Method for checking and controlling the mammalian lactic acid fermentation process/aerobic glucose fermentation metabolic pathway in mammalian organism |
Publications (1)
Publication Number | Publication Date |
---|---|
DK2256500T3 true DK2256500T3 (da) | 2014-07-14 |
Family
ID=36224891
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK10009323.6T DK2256500T3 (da) | 2005-03-07 | 2006-03-03 | Anvendelse af inhibitorer af enzymet TKTL1 |
DK06723195.1T DK1856537T3 (da) | 2005-03-07 | 2006-03-03 | Fremgangsmåde til check og kontrol af pattedyr-mælkesyrefermentationsprocessen/stofskiftepathwayen for aerob glocosefermentation i pattedyr-organismer |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK06723195.1T DK1856537T3 (da) | 2005-03-07 | 2006-03-03 | Fremgangsmåde til check og kontrol af pattedyr-mælkesyrefermentationsprocessen/stofskiftepathwayen for aerob glocosefermentation i pattedyr-organismer |
Country Status (11)
Country | Link |
---|---|
US (3) | US7754437B2 (da) |
EP (2) | EP1856537B1 (da) |
JP (1) | JP5095600B2 (da) |
AT (1) | ATE509279T1 (da) |
AU (1) | AU2006222277B2 (da) |
CA (1) | CA2600206C (da) |
DK (2) | DK2256500T3 (da) |
ES (1) | ES2480416T3 (da) |
PL (2) | PL2256500T3 (da) |
PT (1) | PT2256500E (da) |
WO (1) | WO2006094716A1 (da) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE102007013903A1 (de) | 2007-03-20 | 2008-09-25 | Coy, Johannes F., Dr. | Getränk |
DE102010007243B4 (de) * | 2010-02-09 | 2011-11-17 | Frank Kischkel | Therapieoptimierung bei Krebspatienten durch Austesten von Therapiekombinationen mittels in vitro Testungen (Zusatz) |
DE102011008016A1 (de) | 2011-01-06 | 2012-07-12 | Johannes F. Coy | Schokoladenmasse |
DE102020116980A1 (de) | 2020-06-27 | 2021-12-30 | TAVARGENIX GmbH | Verwendung von Co-Enzym-Antagonisten zur Stoffwechselverlangsamung |
CN112730734A (zh) * | 2020-12-22 | 2021-04-30 | 河南星汉生物科技有限公司 | 一种葡萄糖发酵乳酸中发酵液残糖的检验方法 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4006219A (en) * | 1972-08-10 | 1977-02-01 | Ceres Pharmacal Company | Composition and method for countering effects of alcohol consumption |
DE2834706A1 (de) * | 1978-08-08 | 1980-02-14 | Boehringer Mannheim Gmbh | Verfahren und reagens zur bestimmung von glutamat-oxalacetat-transaminase und glutamat-pyruvat-transaminase |
US4594237A (en) * | 1984-04-16 | 1986-06-10 | Walter Ziegler | Method for testing chemical and biological substances |
US6919185B2 (en) * | 2000-05-31 | 2005-07-19 | Bayer Aktiengesellschaft | Regulation of human transketolase-like enzyme |
US7381713B2 (en) * | 2000-12-04 | 2008-06-03 | Sioan-Kettering Institute For Cancer Research | Treatment of cancer by reduction of intracellular energy and pyrimidines |
ES2298304T3 (es) * | 2002-04-19 | 2008-05-16 | Johannes Dr. Coy | Composiciones y procedimientos para la deteccion y tratamiento de anormalidades proliferativas asociadas con la sobreexpresion de gen like-1 de transcetolasa humano. |
-
2006
- 2006-03-03 CA CA2600206A patent/CA2600206C/en active Active
- 2006-03-03 PL PL10009323T patent/PL2256500T3/pl unknown
- 2006-03-03 US US11/571,205 patent/US7754437B2/en active Active
- 2006-03-03 PT PT100093236T patent/PT2256500E/pt unknown
- 2006-03-03 PL PL06723195T patent/PL1856537T3/pl unknown
- 2006-03-03 AU AU2006222277A patent/AU2006222277B2/en active Active
- 2006-03-03 EP EP06723195A patent/EP1856537B1/en active Active
- 2006-03-03 AT AT06723195T patent/ATE509279T1/de active
- 2006-03-03 DK DK10009323.6T patent/DK2256500T3/da active
- 2006-03-03 ES ES10009323.6T patent/ES2480416T3/es active Active
- 2006-03-03 JP JP2008500098A patent/JP5095600B2/ja active Active
- 2006-03-03 WO PCT/EP2006/001951 patent/WO2006094716A1/en not_active Application Discontinuation
- 2006-03-03 EP EP10009323.6A patent/EP2256500B1/en active Active
- 2006-03-03 DK DK06723195.1T patent/DK1856537T3/da active
-
2010
- 2010-05-28 US US12/790,257 patent/US11236381B2/en active Active
-
2020
- 2020-01-29 US US16/775,454 patent/US11359225B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
PL2256500T3 (pl) | 2014-10-31 |
US20200248227A1 (en) | 2020-08-06 |
AU2006222277A1 (en) | 2006-09-14 |
US11359225B2 (en) | 2022-06-14 |
PT2256500E (pt) | 2014-07-18 |
EP2256500B1 (en) | 2014-04-23 |
US20100240687A1 (en) | 2010-09-23 |
JP5095600B2 (ja) | 2012-12-12 |
CA2600206C (en) | 2011-01-04 |
EP2256500A2 (en) | 2010-12-01 |
ES2480416T3 (es) | 2014-07-28 |
PL1856537T3 (pl) | 2011-10-31 |
EP2256500A3 (en) | 2012-08-29 |
US20080095703A1 (en) | 2008-04-24 |
ATE509279T1 (de) | 2011-05-15 |
DK1856537T3 (da) | 2011-07-18 |
AU2006222277B2 (en) | 2011-04-07 |
EP1856537B1 (en) | 2011-05-11 |
EP1856537A1 (en) | 2007-11-21 |
US7754437B2 (en) | 2010-07-13 |
US11236381B2 (en) | 2022-02-01 |
WO2006094716A1 (en) | 2006-09-14 |
CA2600206A1 (en) | 2006-09-14 |
JP2008531065A (ja) | 2008-08-14 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
BRPI0418539A (pt) | sistema de teste de analito para a determinação da concentração de um analito em um fluido fisiológico | |
EP3426766B1 (en) | Method for continuous biosensing | |
CL2008003629A1 (es) | Metodo de analisis microbiologico de muestras biologicas que comprende un primer intervalo de tiempo de incubacion, tras el cual las muestras que dividen en 3 categorias (positivas, negativas o inciertas) dependiendo de la cantidad de dioxido de carbono generado, y donde las muestra que presentan un contenido de dioxido de carbono comprendido entre un valor maximo y minimo (muestras inciertas), se someten a un segundo intervalo de tiempo de incubacion y asi categorizarlas como positivas o negativas. | |
ATE470859T1 (de) | Schneller und empfindlicher nachweis von molekülen | |
DK2256500T3 (da) | Anvendelse af inhibitorer af enzymet TKTL1 | |
Tulpule et al. | Primary cultures of astrocytes and neurons as model systems to study the metabolism and metabolite export from brain cells | |
ATE412905T1 (de) | Diagnoseverfahren für lebersteatose unter verwendung biochemischer marker | |
BRPI0607912A2 (pt) | ensaio para determinar a presença, ausência ou saúde de uma célula, analito, ácido nucléico ou microorganismo em uma amostra, sonda, métodos para selecionar um analito que se ligue a um composto, para determinar se um ácido nucléico de interesse interage com uma proteína de interesse em uma célula ou uma amostra invitro, e para determinar a presença ou ausência de um ou mais compostos alvo em uma amostra, kit para manchar células, analitos, ácidos nucléicos ou microorganismos em uma amostra, e, composto" | |
DE602006003615D1 (de) | Glukosebiosensor und Verfahren | |
Rajan et al. | Monitoring pH, temperature and humidity in long-term stem cell culture in CO 2 incubator | |
Dietzsch et al. | On-line multiple component analysis for efficient quantitative bioprocess development | |
EP2662453A3 (en) | Detection and treatment of schizophrenia | |
Martinez et al. | A cell culture model that mimics physiological tissue oxygenation using oxygen-permeable membranes | |
ATE475884T1 (de) | Detektion von zirkulierenden endothelzellen | |
Lamboursain et al. | A lab‐built respirometer for plant and animal cell culture | |
CN103645332B (zh) | 自动化高通量检测胆固醇以及其它分析物细胞流出的多功能工作站 | |
ATE465271T1 (de) | Methode und apparat zur messung von amylase aktivität | |
ATE455867T1 (de) | Echtzeit-pcr unter zusatz von pyrophosphatase | |
Dahlmann et al. | Online monitoring of the cell-specific oxygen uptake rate with an in situ combi-sensor | |
CN105669661A (zh) | 一种半胱氨酸检测试剂及其制备方法 | |
CN208023017U (zh) | 一种血液感染微生物的快速检测*** | |
JP5021273B2 (ja) | 老化度の判断方法 | |
WO2006100346A1 (en) | Method for determining prothrombin time | |
WO2023107879A1 (en) | Method and apparatus for sterile and noninvasive measurements of substances in bioreactors and other sterile environments | |
Otto | Cell cultivation and sensor-based assays for dynamic measurements of cell vitality |