DK218386A - Konjugater af antistof og terapeutisk middel - Google Patents
Konjugater af antistof og terapeutisk middel Download PDFInfo
- Publication number
- DK218386A DK218386A DK218386A DK218386A DK218386A DK 218386 A DK218386 A DK 218386A DK 218386 A DK218386 A DK 218386A DK 218386 A DK218386 A DK 218386A DK 218386 A DK218386 A DK 218386A
- Authority
- DK
- Denmark
- Prior art keywords
- conjugates
- antibody
- therapeutic agent
- therapeutic
- agent
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
- A61K51/1093—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody conjugates with carriers being antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/0042—Photocleavage of drugs in vivo, e.g. cleavage of photolabile linkers in vivo by UV radiation for releasing the pharmacologically-active agent from the administered agent; photothrombosis or photoocclusion
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
- A61K41/0071—PDT with porphyrins having exactly 20 ring atoms, i.e. based on the non-expanded tetrapyrrolic ring system, e.g. bacteriochlorin, chlorin-e6, or phthalocyanines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2121/00—Preparations for use in therapy
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US65075484A | 1984-09-13 | 1984-09-13 | |
US06/650,375 US4867973A (en) | 1984-08-31 | 1984-09-13 | Antibody-therapeutic agent conjugates |
PCT/US1985/001700 WO1986001720A1 (fr) | 1984-09-13 | 1985-09-10 | Conjugues d'agents therapeutiques-anticorps |
Publications (2)
Publication Number | Publication Date |
---|---|
DK218386D0 DK218386D0 (da) | 1986-05-12 |
DK218386A true DK218386A (da) | 1986-07-11 |
Family
ID=27095841
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK218386A DK218386A (da) | 1984-09-13 | 1986-05-12 | Konjugater af antistof og terapeutisk middel |
Country Status (7)
Country | Link |
---|---|
EP (1) | EP0175617B1 (fr) |
AU (2) | AU583854B2 (fr) |
CA (1) | CA1326834C (fr) |
DE (1) | DE3584559D1 (fr) |
DK (1) | DK218386A (fr) |
GR (1) | GR852217B (fr) |
WO (1) | WO1986001720A1 (fr) |
Families Citing this family (56)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5140104A (en) * | 1982-03-09 | 1992-08-18 | Cytogen Corporation | Amine derivatives of folic acid analogs |
US4831122A (en) * | 1986-01-09 | 1989-05-16 | Regents Of The University Of Minnesota | Radioimmunotoxins |
CA1330378C (fr) * | 1986-05-08 | 1994-06-21 | Daniel J. Coughlin | Derives amine d'analogues de l'acide folique |
US4801688A (en) * | 1986-05-27 | 1989-01-31 | Eli Lilly And Company | Hydrazone immunoglobulin conjugates |
GB8628398D0 (en) * | 1986-11-27 | 1986-12-31 | Central Blood Lab Authority | Pharmaceutically-active conjugates |
US4835258A (en) * | 1986-12-24 | 1989-05-30 | Northwestsern University | Conjugation of aromatic amines or nitro-containing compounds with proteins or polypeptides by photoirradiation of the azide derivatives with ultraviolet light in order to produce antibodies against the haptens |
US5079361A (en) * | 1987-01-15 | 1992-01-07 | Celltech Limited | Thiol-reactive cross-linking reagents |
US5283255A (en) * | 1987-01-20 | 1994-02-01 | The University Of British Columbia | Wavelength-specific cytotoxic agents |
US5095030A (en) * | 1987-01-20 | 1992-03-10 | University Of British Columbia | Wavelength-specific cytotoxic agents |
US4920143A (en) * | 1987-04-23 | 1990-04-24 | University Of British Columbia | Hydro-monobenzoporphyrin wavelength-specific cytotoxic agents |
US4883790A (en) * | 1987-01-20 | 1989-11-28 | University Of British Columbia | Wavelength-specific cytotoxic agents |
US5171749A (en) * | 1987-01-20 | 1992-12-15 | University Of British Columbia | Wavelength-specific cytotoxic agents |
FR2610198B1 (fr) * | 1987-02-03 | 1990-06-15 | Ire Celltarg Sa | Conjugues d'hydrazide d'alcaloide de vinca lie a une immunoglobuline, procede de preparation et compositions pharmaceutiques en comprenant |
FR2611141B1 (fr) * | 1987-02-20 | 1991-02-01 | Int Rech Cancer Centre | Ensemble ou kit pour utilisation comme agent pour la destruction selective de cellules transformees ou tumorales |
EP0282057A3 (fr) * | 1987-03-11 | 1990-03-07 | The Board Of Regents Of The University Of Michigan | Produits associés chémo-radio-immunologiques |
US4937183A (en) * | 1988-02-03 | 1990-06-26 | Cytogen Corporation | Method for the preparation of antibody-fragment conjugates |
US5047227A (en) * | 1988-02-08 | 1991-09-10 | Cytogen Corporation | Novel and improved antibodies for site specific attachment of compounds |
EP0336383A3 (fr) * | 1988-04-07 | 1990-08-16 | Takeda Chemical Industries, Ltd. | Lymphotoxine recombinante humaine |
USRE38994E1 (en) | 1988-07-20 | 2006-02-28 | Health Research, Inc. | Pyropheophorbides conjugates and their use in photodynamic therapy |
USRE39094E1 (en) | 1988-07-20 | 2006-05-09 | Health Research, Inc. | Pyropheophorbides and their use in photodynamic therapy |
DE3827940A1 (de) * | 1988-08-13 | 1990-03-01 | Schering Ag | 13,17-propionsaeure- und propionsaeurederivat- substituierte porphyrin-komplexverbindungen, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische mittel |
WO1990003401A1 (fr) * | 1988-09-30 | 1990-04-05 | Neorx Corporation | Conjugues de substance de ciblage et d'agent diagnostique/therapeutique comportant des liaisons de base de schiff |
US5066789A (en) * | 1988-09-30 | 1991-11-19 | Neorx Corporation | Targeting substance-diagnostic/therapeutic agent conjugates having Schiff base linkages |
US5270302A (en) * | 1988-12-21 | 1993-12-14 | Abbott Laboratories | Derivatives of tetrapeptides as CCK agonists |
GR890100827A (el) * | 1988-12-21 | 1991-03-15 | Abbott Lab | Μέ?οδος παραγωγής παραγώγων τετραπεπτιδίων ως ανταγωνιστών CCK. |
US5308608A (en) * | 1989-06-07 | 1994-05-03 | University Of British Columbia | Photosensitizing Diels-Alder porphyrin derivatives |
CA2056431A1 (fr) * | 1989-06-07 | 1990-12-08 | David Dolphin | Photosensibilisation de derives de la porphyrine obtenus par additions diels-alder |
EP0449998A4 (en) * | 1989-06-30 | 1992-01-15 | Brunswick Corporation | Antibody-oxidase conjugates with non-systemic substrates |
CA2069439A1 (fr) * | 1989-12-15 | 1991-06-16 | Susumu Iwasa | Anticorps monoclonaux, leur production et leur utilisation |
CA2078118C (fr) * | 1990-04-25 | 1999-11-16 | Paul A. Aristoff | Analogues de cc-1065 |
EP0553116A1 (fr) * | 1990-10-05 | 1993-08-04 | Queen's University At Kingston | Derives de prophyrine |
US5272253A (en) * | 1991-07-01 | 1993-12-21 | Eli Lilly And Company | Cluster conjugates of drugs with antibodies |
GR1001459B (el) * | 1992-10-08 | 1993-12-30 | Lilly Co Eli | Σύμπλεγμα συζυγών φαρμάκων με αντισώματα. |
WO1997033620A2 (fr) * | 1996-03-15 | 1997-09-18 | Pulsion Verw. Gmbh & Co. Medical Systems Kg | Compose pour traiter des tumeurs |
US7390668B2 (en) | 1996-10-30 | 2008-06-24 | Provectus Pharmatech, Inc. | Intracorporeal medicaments for photodynamic treatment of disease |
US6493570B1 (en) * | 1998-11-02 | 2002-12-10 | Photogen, Inc. | Method for improved imaging and photodynamic therapy |
ITRM960808A1 (it) * | 1996-11-26 | 1998-05-26 | Rossolini Gianmaria | Immunoconiugati comprendenti anticorpi monoclonali umani o frammenti di essi per diagnosi in vivo e terapia |
DE19717904A1 (de) * | 1997-04-23 | 1998-10-29 | Diagnostikforschung Inst | Säurelabile und enzymatisch spaltbare Farbstoffkonstrukte zur Diagnostik mit Nahinfrarotlicht und zur Therapie |
US8557298B2 (en) | 1998-08-06 | 2013-10-15 | Provectus Pharmatech, Inc. | Medicaments for chemotherapeutic treatment of disease |
US7648695B2 (en) | 1998-08-06 | 2010-01-19 | Provectus Pharmatech, Inc. | Medicaments for chemotherapeutic treatment of disease |
US6602274B1 (en) | 1999-01-15 | 2003-08-05 | Light Sciences Corporation | Targeted transcutaneous cancer therapy |
CA2356532A1 (fr) | 1999-01-15 | 2000-07-20 | Light Sciences Corporation | Therapie vasculaire non invasive |
ATE406157T1 (de) | 1999-08-13 | 2008-09-15 | Provectus Pharmatech Inc | Verbesserte topische medikamente sowie verfahren zur photodynamischer behandlung von krankheiten |
EP1653996A2 (fr) * | 2003-08-08 | 2006-05-10 | Novo Nordisk Health Care AG | Utilisation de galactose oxydase pour la conjugaison chimique selective de molecules d'extraction a des proteines d'interet therapeutique |
WO2005047507A1 (fr) * | 2003-11-12 | 2005-05-26 | The Austin Research Institute | Conjugue adn-excipient |
US7541330B2 (en) | 2004-06-15 | 2009-06-02 | Kosan Biosciences Incorporated | Conjugates with reduced adverse systemic effects |
EP2380909A1 (fr) | 2010-04-26 | 2011-10-26 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Protéine PTK-7 impliquée dans le cancer du sein |
US9517257B2 (en) | 2010-08-10 | 2016-12-13 | Ecole Polytechnique Federale De Lausanne (Epfl) | Erythrocyte-binding therapeutics |
US9850296B2 (en) | 2010-08-10 | 2017-12-26 | Ecole Polytechnique Federale De Lausanne (Epfl) | Erythrocyte-binding therapeutics |
CA2807942C (fr) | 2010-08-10 | 2021-07-27 | Ecole Polytechnique Federale De Lausanne | Agents therapeutiques se liant aux erythrocytes |
AU2015233084B2 (en) | 2014-02-21 | 2020-12-17 | Anokion Sa | Glycotargeting therapeutics |
US10046056B2 (en) | 2014-02-21 | 2018-08-14 | École Polytechnique Fédérale De Lausanne (Epfl) | Glycotargeting therapeutics |
US10946079B2 (en) | 2014-02-21 | 2021-03-16 | Ecole Polytechnique Federale De Lausanne | Glycotargeting therapeutics |
US10953101B2 (en) | 2014-02-21 | 2021-03-23 | École Polytechnique Fédérale De Lausanne (Epfl) | Glycotargeting therapeutics |
WO2018232176A1 (fr) | 2017-06-16 | 2018-12-20 | The University Of Chicago | Compositions et procédés d'induction d'une tolérance immunitaire |
WO2019136335A1 (fr) * | 2018-01-05 | 2019-07-11 | Gencyte Therapeutics, Inc. | Système adaptateur moléculaire de précision pour une immunothérapie par lymphocytes t à récepteur antigénique chimérique |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3970521A (en) * | 1974-08-07 | 1976-07-20 | Exxon Research And Engineering Company | Immobilized glycoenzymes |
CA1083508A (fr) * | 1975-11-13 | 1980-08-12 | Jacques Grange | Supports porteurs de chaines laterales, procedes d'obtention de ces supports, procedes de fixation de composes organiques comportant un residu glucidique sur lesdits supports, produits et reactifs resultant de ladite fixation chimique |
JPS52141882A (en) * | 1976-05-20 | 1977-11-26 | Hidetoshi Tsuchida | Highhpolymeric complex of covalent type |
CA1203164A (fr) * | 1982-03-09 | 1986-04-15 | Thomas J. Mckearn | Conjugats d'anticorps |
-
1985
- 1985-09-10 WO PCT/US1985/001700 patent/WO1986001720A1/fr unknown
- 1985-09-10 AU AU48071/85A patent/AU583854B2/en not_active Ceased
- 1985-09-11 CA CA000490424A patent/CA1326834C/fr not_active Expired - Lifetime
- 1985-09-12 GR GR852217A patent/GR852217B/el unknown
- 1985-09-13 DE DE8585401776T patent/DE3584559D1/de not_active Expired - Fee Related
- 1985-09-13 EP EP85401776A patent/EP0175617B1/fr not_active Expired - Lifetime
-
1986
- 1986-05-12 DK DK218386A patent/DK218386A/da not_active Application Discontinuation
-
1989
- 1989-02-21 AU AU30161/89A patent/AU3016189A/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP0175617A3 (en) | 1988-06-15 |
EP0175617B1 (fr) | 1991-10-30 |
AU583854B2 (en) | 1989-05-11 |
AU3016189A (en) | 1989-07-13 |
CA1326834C (fr) | 1994-02-08 |
EP0175617A2 (fr) | 1986-03-26 |
AU4807185A (en) | 1986-04-08 |
DK218386D0 (da) | 1986-05-12 |
GR852217B (fr) | 1986-01-14 |
WO1986001720A1 (fr) | 1986-03-27 |
DE3584559D1 (de) | 1991-12-05 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
AHB | Application shelved due to non-payment |