DK2164964T3 - Dehydrerede chitosanpartikler - Google Patents

Dehydrerede chitosanpartikler

Info

Publication number
DK2164964T3
DK2164964T3 DK08758308.4T DK08758308T DK2164964T3 DK 2164964 T3 DK2164964 T3 DK 2164964T3 DK 08758308 T DK08758308 T DK 08758308T DK 2164964 T3 DK2164964 T3 DK 2164964T3
Authority
DK
Denmark
Prior art keywords
nanoparticles
dehydrated
particles
nucleic acid
chitosan particles
Prior art date
Application number
DK08758308.4T
Other languages
English (en)
Inventor
Ja Rgen Kjems
Morten A Stergaard Andersen
Kenneth Alan Howard
Flemming Besenbacher
Original Assignee
Univ Aarhus
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Aarhus filed Critical Univ Aarhus
Application granted granted Critical
Publication of DK2164964T3 publication Critical patent/DK2164964T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A61K48/0008Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'non-active' part of the composition delivered, e.g. wherein such 'non-active' part is not delivered simultaneously with the 'active' part of the composition
    • A61K48/0025Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'non-active' part of the composition delivered, e.g. wherein such 'non-active' part is not delivered simultaneously with the 'active' part of the composition wherein the non-active part clearly interacts with the delivered nucleic acid
    • A61K48/0041Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'non-active' part of the composition delivered, e.g. wherein such 'non-active' part is not delivered simultaneously with the 'active' part of the composition wherein the non-active part clearly interacts with the delivered nucleic acid the non-active part being polymeric
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51Nanocapsules; Nanoparticles
    • A61K9/5107Excipients; Inactive ingredients
    • A61K9/513Organic macromolecular compounds; Dendrimers
    • A61K9/5161Polysaccharides, e.g. alginate, chitosan, cellulose derivatives; Cyclodextrin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/111General methods applicable to biologically active non-coding nucleic acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/10Type of nucleic acid
    • C12N2310/14Type of nucleic acid interfering N.A.
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2320/00Applications; Uses
    • C12N2320/50Methods for regulating/modulating their activity
    • C12N2320/51Methods for regulating/modulating their activity modulating the chemical stability, e.g. nuclease-resistance

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physics & Mathematics (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Nanotechnology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Separation Of Suspended Particles By Flocculating Agents (AREA)
DK08758308.4T 2007-07-06 2008-07-04 Dehydrerede chitosanpartikler DK2164964T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA200701004 2007-07-06
PCT/DK2008/050171 WO2009006905A1 (en) 2007-07-06 2008-07-04 Dehydrated chitosan nanoparticles

Publications (1)

Publication Number Publication Date
DK2164964T3 true DK2164964T3 (da) 2011-12-05

Family

ID=39790018

Family Applications (1)

Application Number Title Priority Date Filing Date
DK08758308.4T DK2164964T3 (da) 2007-07-06 2008-07-04 Dehydrerede chitosanpartikler

Country Status (7)

Country Link
US (1) US20110033547A1 (da)
EP (1) EP2164964B1 (da)
AT (1) ATE523592T1 (da)
CA (1) CA2729923A1 (da)
DK (1) DK2164964T3 (da)
ES (1) ES2376200T3 (da)
WO (1) WO2009006905A1 (da)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2176411B1 (en) 2007-07-23 2012-04-18 Aarhus Universitet Nanoparticle-mediated treatment for inflammatory diseases
JP5804453B2 (ja) * 2009-05-14 2015-11-04 国立大学法人 東京大学 結晶性ポリオール微粒子及びその調製方法
EP2758036A2 (en) * 2011-09-21 2014-07-30 Yissum Research and Development Company of The Hebrew University of Jerusalem Nano delivery systems
EP2591770B1 (en) * 2011-11-14 2016-03-16 Silenseed Ltd Compositions for siRNA delivery and methods of manufacturing and using same
MX2014008404A (es) 2012-01-27 2014-08-22 Hoffmann La Roche Quitosan enlazado covalentamente con antagonista de la integrina de molecula pequeña para suministro dirigido.
GB201220675D0 (en) * 2012-11-16 2013-01-02 Univ Singapore Process and materials for medical applications
WO2014197970A1 (en) * 2013-06-10 2014-12-18 Polyvalor, Société En Commandite Freeze-dried polyelectrolyte complexes that maintain size and biological activity
JP6721514B2 (ja) * 2014-02-20 2020-07-15 オルト リジェネレイティヴ テクノロジーズ インク.Ortho Regenerative Technologies Inc. 多血小板血漿と混合し、組織修復のためのインプラントを形成するための凍結乾燥ポリマー組成物及び/又は治療用関節内注射のための組成物
CN105031746B (zh) * 2015-09-10 2017-11-03 李健 一种壳聚糖携载siRNA涂层血管支架及其制备方法
GB201520600D0 (en) 2015-11-23 2016-01-06 Univ Leuven Kath Treatment of central nervous tumours
MX2018013122A (es) 2016-04-26 2019-03-28 Viaqua Therapeutics Ltd Composiciones y procedimientos para tratar infecciones viricas en gambas.
CN107875400B (zh) * 2017-11-20 2020-10-30 南通大学 一种壳-核结构的siRNA仿病毒递送***及应用
WO2023084510A1 (en) 2021-11-09 2023-05-19 Viaqua Therapeutics Ltd. Compositions for aquaculturing

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2257408A1 (en) * 1996-07-10 1998-01-15 Lisbeth Illum Compositions suitable for delivery of genes to epithelial cells
JP2003265171A (ja) * 2002-03-15 2003-09-24 Koike Kagaku Kk 遺伝子ドライパウダー及びその調製方法並びに遺伝子ドライパウダーの調製装置
US20060286142A1 (en) * 2005-06-03 2006-12-21 Biohesion, Inc. Gold surfaces coated with a thermostable chemically resistant polypeptide layer and applications thereof
US20070299043A1 (en) * 2005-10-03 2007-12-27 Hunter William L Anti-scarring drug combinations and use thereof
DOP2006000268A (es) * 2005-12-22 2007-07-31 Pfizer Prod Inc Agentes antibacterianos
JP2007224012A (ja) * 2006-01-30 2007-09-06 Fujifilm Corp 酵素架橋したタンパク質ナノ粒子
KR20090031861A (ko) * 2006-05-24 2009-03-30 어드밴스드 인 비트로 셀 테크놀로지스, 에스.에이 활성분자의 투여를 위한 키토산 및 하이알루로난 나노입자
US20100092572A1 (en) * 2007-01-29 2010-04-15 Peter Kaeuper Chitosan-based colloidal particles for rna delivery

Also Published As

Publication number Publication date
WO2009006905A1 (en) 2009-01-15
EP2164964A1 (en) 2010-03-24
CA2729923A1 (en) 2009-01-15
US20110033547A1 (en) 2011-02-10
ATE523592T1 (de) 2011-09-15
ES2376200T3 (es) 2012-03-09
EP2164964B1 (en) 2011-09-07

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