DK2124638T3 - Sammensætning, der er præstationforøgende, samt anvendelse af den - Google Patents
Sammensætning, der er præstationforøgende, samt anvendelse af den Download PDFInfo
- Publication number
- DK2124638T3 DK2124638T3 DK08712839.3T DK08712839T DK2124638T3 DK 2124638 T3 DK2124638 T3 DK 2124638T3 DK 08712839 T DK08712839 T DK 08712839T DK 2124638 T3 DK2124638 T3 DK 2124638T3
- Authority
- DK
- Denmark
- Prior art keywords
- nitrate
- nitrite
- vol
- combination
- inorganic
- Prior art date
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- Orthopedic Medicine & Surgery (AREA)
- Pulmonology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Claims (9)
1. Fremgangsmåde til ikke-terapeutisk forøgelse af et pattedyrs præstation, hvor den forøgede præstation ved fysisk udøvelse ytrer sig ved reduceret oxygenforbrug (VO2), kendetegnet ved, at uorganisk nitrat, nitrit eller en kombination deraf indgives oralt, hvor dosen af nitrat andrager 0,01 - 10 mmol natriumnitrat/kg le-gemsvægt/dag, dosen af nitrit andrager 0,001 - 1 mmol/kg legemsvægt/dag, og hvor doseforholdsintervallet, når nitrat og nitrit indgives i kombination, andrager 5:1 til 100:1 (nitratmitrit), og hvor den nævnte præstation er forøget i sammenligning med pattedyrets fysiske præstation ved fravær af indgivelse af uorganisk nitrat og/eller nitrit.
2. Fremgangsmåde ifølge krav 1, hvor nitrat og/eller nitrit indgives sammen med polyphenoler.
3. Anvendelse af uorganisk nitrat eller nitrit eller en kombination deraf til ikke-terapeutisk forøgelse af et pattedyrs præstation, hvor den forøgede præstation under fysisk udøvelse ytrer sig ved formindsket oxygenforbrug (VO2), kendetegnet ved, at uorganisk nitrat, nitrit eller en kombination deraf indgives oralt, hvor dosen af nitrat andrager 0,01 - 10 mmol natriumnitrat/kg legemsvægt/dag, dosen af nitrit andrager 0,001 - 1 mmol/kg legemsvægt/dag, og hvor doseforholdsintervallet, når nitrat og nitrit indgives i kombination, andrager 5:1 til 100:1 (nitratmitrit), og hvor den nævnte præstation er forøget i sammenligning med pattedyrets fysiske præstation ved fravær af indgivelse af uorganisk nitrat og/eller nitrit.
4. Anvendelse ifølge krav 3, hvor sammensætningen foreligger i form af en væske, en pasta, en stang (barre), en kage, et pulver, et granulat, en brusetablet, en tablet, en kapsel, en pastil, en tyggegummi, en hurtig smeltende smelte-tablet eller -wafer, en sugetablet eller en spray.
5. Anvendelse ifølge krav 3 eller 4, hvor sammensætningen foreligger i form af en sportsdrik, en energidrik, en sportsstang eller -barre eller en energi-stang eller -barre.
6. Anvendelse ifølge krav 3, 4 eller 5, hvor kilden til uorganisk nitrat er udvalgt blandt et koncentrat, en ekstrakt eller en juice af nitrat-holdige grøntsager eller en uorganisk nitratsalt.
7. Anvendelse ifølge krav 3, 4, 5 eller 6, hvor den uorganiske nitrat er anvendt i kombination med polyphenoler.
8. Anvendelse ifølge krav 3, 4, 5, 6 eller 7, hvor den uorganiske nitrat er anvendt i kombination med levende bakterier, som er i stand til forøgelse af nitrat- eller nitrit-reduktion.
9. Anvendelse ifølge krav 3, 4, 5, 6, 7 eller 8, hvor den uorganiske nitrat er anvendt i kombination med ethanol i en mængde mindre end 5 % (v/v), fortrinsvis mindre end 2 % (v/v), mere foretrukket imellem 0,5 - 1 % (v/v).
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
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| SE0700520 | 2007-02-26 | ||
| SE0700729 | 2007-03-22 | ||
| PCT/SE2008/050211 WO2008105730A1 (en) | 2007-02-26 | 2008-02-26 | Performance enhancing composition and use thereof |
Publications (1)
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| DK2124638T3 true DK2124638T3 (da) | 2017-03-20 |
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| DK08712839.3T DK2124638T3 (da) | 2007-02-26 | 2008-02-26 | Sammensætning, der er præstationforøgende, samt anvendelse af den |
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| EP (2) | EP3159000A1 (da) |
| JP (1) | JP2010519335A (da) |
| CA (1) | CA2678093C (da) |
| CY (1) | CY1118847T1 (da) |
| DK (1) | DK2124638T3 (da) |
| ES (1) | ES2618655T3 (da) |
| HR (1) | HRP20170355T1 (da) |
| HU (1) | HUE031982T2 (da) |
| PL (1) | PL2124638T3 (da) |
| PT (1) | PT2124638T (da) |
| WO (1) | WO2008105730A1 (da) |
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| US10835555B2 (en) | 2007-02-26 | 2020-11-17 | Heartbeet Ltd | Compositions of nitrates and methods of use thereof |
| US10406118B2 (en) | 2007-02-26 | 2019-09-10 | Jon Lundberg | Use of nitrites and nitrates and compositions containing these |
| US10821132B2 (en) | 2007-02-26 | 2020-11-03 | Heartbeet Ltd | Compositions of nitrates and methods of use thereof |
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| ES2633618T3 (es) | 2009-10-14 | 2017-09-22 | Theravasc Inc. | Formulaciones farmacéuticas de nitrito y sus usos |
| HUE032165T2 (en) | 2011-04-13 | 2017-09-28 | Thermolife Int Llc | Methods of using N-actyl-beta-alanine |
| BR112014003414B1 (pt) * | 2011-08-17 | 2021-09-21 | Board Of Regents, The University Of Texas System | Composição e sistema de entrega oral para aumento de níveis fisiológicos e terapêuticos de óxido nítrico |
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-
2008
- 2008-02-26 EP EP16202454.1A patent/EP3159000A1/en active Pending
- 2008-02-26 HU HUE08712839A patent/HUE031982T2/en unknown
- 2008-02-26 ES ES08712839.3T patent/ES2618655T3/es active Active
- 2008-02-26 CA CA2678093A patent/CA2678093C/en active Active
- 2008-02-26 PL PL08712839T patent/PL2124638T3/pl unknown
- 2008-02-26 JP JP2009551970A patent/JP2010519335A/ja active Pending
- 2008-02-26 DK DK08712839.3T patent/DK2124638T3/da active
- 2008-02-26 PT PT87128393T patent/PT2124638T/pt unknown
- 2008-02-26 US US12/528,798 patent/US9180140B2/en active Active
- 2008-02-26 WO PCT/SE2008/050211 patent/WO2008105730A1/en active Application Filing
- 2008-02-26 EP EP08712839.3A patent/EP2124638B1/en active Active
-
2015
- 2015-08-20 US US14/830,937 patent/US10555968B2/en active Active
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2017
- 2017-03-03 HR HRP20170355TT patent/HRP20170355T1/hr unknown
- 2017-03-07 CY CY20171100294T patent/CY1118847T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HUE031982T2 (en) | 2017-08-28 |
| EP2124638A1 (en) | 2009-12-02 |
| EP2124638A4 (en) | 2014-04-02 |
| HRP20170355T1 (hr) | 2017-05-19 |
| ES2618655T3 (es) | 2017-06-21 |
| PT2124638T (pt) | 2017-03-13 |
| JP2010519335A (ja) | 2010-06-03 |
| CA2678093C (en) | 2017-10-24 |
| EP3159000A1 (en) | 2017-04-26 |
| WO2008105730A1 (en) | 2008-09-04 |
| CY1118847T1 (el) | 2018-01-10 |
| US20150352147A1 (en) | 2015-12-10 |
| CA2678093A1 (en) | 2008-09-04 |
| EP2124638B1 (en) | 2016-12-07 |
| US9180140B2 (en) | 2015-11-10 |
| US20100047344A1 (en) | 2010-02-25 |
| US10555968B2 (en) | 2020-02-11 |
| PL2124638T3 (pl) | 2017-07-31 |
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