DK2094676T3 - Ny fremgangsmåde til fremstillingen af 2-iminothiazolidin-4-on-derivater - Google Patents

Ny fremgangsmåde til fremstillingen af 2-iminothiazolidin-4-on-derivater

Info

Publication number
DK2094676T3
DK2094676T3 DK07849225.3T DK07849225T DK2094676T3 DK 2094676 T3 DK2094676 T3 DK 2094676T3 DK 07849225 T DK07849225 T DK 07849225T DK 2094676 T3 DK2094676 T3 DK 2094676T3
Authority
DK
Denmark
Prior art keywords
iminothiazolidin
derivatives
preparation
new procedure
procedure
Prior art date
Application number
DK07849225.3T
Other languages
English (en)
Inventor
Stefan Abele
Martin Bolli
Gunther Schmidt
Original Assignee
Actelion Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Actelion Pharmaceuticals Ltd filed Critical Actelion Pharmaceuticals Ltd
Application granted granted Critical
Publication of DK2094676T3 publication Critical patent/DK2094676T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/54—Nitrogen and either oxygen or sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK07849225.3T 2006-11-23 2007-11-22 Ny fremgangsmåde til fremstillingen af 2-iminothiazolidin-4-on-derivater DK2094676T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IB2006054409 2006-11-23
PCT/IB2007/054752 WO2008062376A2 (en) 2006-11-23 2007-11-22 New process for the preparation of 2-imino-thiazolidin-4-one derivatives

Publications (1)

Publication Number Publication Date
DK2094676T3 true DK2094676T3 (da) 2013-06-10

Family

ID=39316391

Family Applications (2)

Application Number Title Priority Date Filing Date
DK07849225.3T DK2094676T3 (da) 2006-11-23 2007-11-22 Ny fremgangsmåde til fremstillingen af 2-iminothiazolidin-4-on-derivater
DK12000613.5T DK2489662T3 (da) 2006-11-23 2007-11-22 Mellemprodukter af en ny fremgangsmåde til fremstillingen af 5-benzyliden-2-alkylimino-3-phenylthiazolidin-4-on derivater

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK12000613.5T DK2489662T3 (da) 2006-11-23 2007-11-22 Mellemprodukter af en ny fremgangsmåde til fremstillingen af 5-benzyliden-2-alkylimino-3-phenylthiazolidin-4-on derivater

Country Status (14)

Country Link
US (1) US8263780B2 (da)
EP (2) EP2094676B1 (da)
JP (1) JP4669564B2 (da)
KR (1) KR101255879B1 (da)
CN (2) CN103087004A (da)
AU (1) AU2007323042B2 (da)
BR (1) BRPI0718986A2 (da)
CA (1) CA2669069C (da)
DK (2) DK2094676T3 (da)
ES (2) ES2410793T3 (da)
IL (1) IL198847A (da)
MX (1) MX2009005048A (da)
TW (1) TWI460166B (da)
WO (1) WO2008062376A2 (da)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE43833E1 (en) 2003-11-21 2012-11-27 Actelion Pharmaceuticals Ltd. Thiazolidin-4-one derivatives
DK1689726T3 (da) 2003-11-21 2010-12-06 Actelion Pharmaceuticals Ltd 5-(benz-(z)-yliden)-thiazolidin-4-on-derivater som immunsuppresserende midler
US8912340B2 (en) 2006-11-23 2014-12-16 Actelion Pharmaceuticals Ltd. Process for the preparation of 2-imino-thiazolidin-4-one derivatives
SI2278960T2 (sl) 2008-03-17 2020-02-28 Actelion Pharmaceuticals Ltd. Režim odmerjanja za selektivni agonist receptorja sip1
GB0819182D0 (en) 2008-10-20 2008-11-26 Actelion Pharmaceuticals Ltd Crystalline forms
HUE050733T2 (hu) * 2012-08-17 2021-01-28 Actelion Pharmaceuticals Ltd Eljárás (2Z,5Z)-5-(3-klór-4-((R)-2,3-dihidroxipropoxi)benzilidén)-2-(pro-pilimino)-3-(O-tolil)tiazolidin-4-on elõállítására és ezen eljárásban alkalmazott köztitermék
WO2016091996A1 (en) 2014-12-11 2016-06-16 Actelion Pharmaceuticals Ltd Dosing regimen for a selective s1p1 receptor agonist
MA41139A (fr) 2014-12-11 2017-10-17 Actelion Pharmaceuticals Ltd Combinaison pharmaceutique comportant un agoniste sélectif du récepteur sip1
JOP20190207A1 (ar) 2017-03-14 2019-09-10 Actelion Pharmaceuticals Ltd تركيبة صيدلانية تشتمل على بونيسيمود
WO2019060147A1 (en) * 2017-09-19 2019-03-28 Teva Pharmaceuticals Usa, Inc. NEW CRYSTALLINE POLYMORPHE FROM PONESIMOD
US11013723B1 (en) 2018-10-16 2021-05-25 Celgene Corporation Solid forms of a thiazolidinone compound, compositions and methods of use thereof
US11186556B1 (en) 2018-10-16 2021-11-30 Celgene Corporation Salts of a thiazolidinone compound, solid forms, compositions and methods of use thereof
US11014897B1 (en) 2018-10-16 2021-05-25 Celgene Corporation Solid forms comprising a thiazolidinone compound, compositions and methods of use thereof
US11014940B1 (en) 2018-10-16 2021-05-25 Celgene Corporation Thiazolidinone and oxazolidinone compounds and formulations
TW202116743A (zh) * 2019-07-10 2021-05-01 德商拜耳廠股份有限公司 製備2-(苯基亞胺基)-1,3-四氫噻唑-4-酮之方法(一)
TW202116742A (zh) * 2019-07-10 2021-05-01 德商拜耳廠股份有限公司 製備2-(苯基亞胺基)-1,3-四氫噻唑-4-酮之方法(二)
JP2023501217A (ja) 2019-10-31 2023-01-18 イドーシア ファーマシューティカルズ リミテッド Ｃｘｃｒ７アンタゴニストのｓ１ｐ１受容体調節剤との合剤
KR20200019639A (ko) 2020-01-30 2020-02-24 전대연 만남의 스마트 도착시스템
IL295464A (en) * 2020-02-18 2022-10-01 Bayer Ag Process for preparing 2-(phenylimino)-3-alkyl-1, 3-thiazolidin-4-ones
WO2023022896A1 (en) 2021-08-17 2023-02-23 Teva Czech Industries S.R.O Polymorphs of ponesimod
EP4212156A1 (en) 2022-01-13 2023-07-19 Abivax Combination of 8-chloro-n-(4-(trifluoromethoxy)phenyl)quinolin-2-amine and its derivatives with a s1p receptor modulator
WO2023152691A1 (en) * 2022-02-10 2023-08-17 Metrochem Api Pvt Ltd Process for the preparation of ponesimod and its intermediates thereof

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US3077402A (en) * 1954-12-06 1963-02-12 Polaroid Corp Photographic color processes, products, and compositions
NL270002A (da) 1960-10-08
OA03835A (fr) * 1970-07-17 1971-12-24 Rhone Poulenc Sa Nouveaux dérivés de la thiazolidine, leur préparation et les compositions qui les contiennent.
WO1991017151A1 (en) * 1990-04-27 1991-11-14 Orion-Yhtymä Oy New pharmacologically active catechol derivatives
TW221689B (da) * 1991-08-27 1994-03-11 Otsuka Pharma Co Ltd
ES2168294T3 (es) * 1993-02-26 2002-06-16 Otsuka Pharma Co Ltd Derivados de tiazol o imidazol inhibidores de la reaccion de maillard.
KR960022486A (ko) 1994-12-29 1996-07-18 김준웅 신규 티아졸리딘-4-온 유도체
US6353006B1 (en) * 1999-01-14 2002-03-05 Bayer Corporation Substituted 2-arylimino heterocycles and compositions containing them, for use as progesterone receptor binding agents
EP1219612B1 (en) 1999-09-14 2008-04-23 Shionogi & Co., Ltd. 2-imino-1,3-thiazine derivatives
ES2276547T3 (es) * 1999-11-12 2007-06-16 Fujimoto Brothers Co., Ltd. Derivados de 2-(n-cianoimino)tiazolidin-4-ona.
US20050019825A9 (en) * 2002-03-15 2005-01-27 Qing Dong Common ligand mimics: pseudothiohydantoins
EA011807B1 (ru) 2002-07-10 2009-06-30 Лаборатуар Сероно Са Азолидинонвинильные производные конденсированного бензола
GB0217152D0 (en) 2002-07-24 2002-09-04 Novartis Ag Organic compounds
DK1567112T3 (da) * 2002-11-22 2009-02-09 Smithkline Beecham Corp Thiazolidin-4-oner til at hæmme hYAK3-proteiner
US20040167192A1 (en) 2003-01-16 2004-08-26 David Solow-Cordero Methods of treating conditions associated with an Edg-7 receptor
DK1689726T3 (da) 2003-11-21 2010-12-06 Actelion Pharmaceuticals Ltd 5-(benz-(z)-yliden)-thiazolidin-4-on-derivater som immunsuppresserende midler
JP2007523957A (ja) * 2004-02-25 2007-08-23 スミスクライン・ビーチャム・コーポレイション 新規化学化合物
WO2006094233A1 (en) * 2005-03-03 2006-09-08 Sirtris Pharmaceuticals, Inc. N,n'-dicyclic isothiourea sirtuin modulators
SI2278960T2 (sl) 2008-03-17 2020-02-28 Actelion Pharmaceuticals Ltd. Režim odmerjanja za selektivni agonist receptorja sip1
GB0819182D0 (en) 2008-10-20 2008-11-26 Actelion Pharmaceuticals Ltd Crystalline forms

Also Published As

Publication number Publication date
ES2523401T3 (es) 2014-11-25
AU2007323042B2 (en) 2012-12-20
CA2669069C (en) 2015-02-17
CN101541772A (zh) 2009-09-23
IL198847A0 (en) 2010-02-17
JP2010510976A (ja) 2010-04-08
MX2009005048A (es) 2009-05-25
EP2094676A2 (en) 2009-09-02
CN101541772B (zh) 2013-04-17
EP2094676B1 (en) 2013-04-10
CA2669069A1 (en) 2008-05-29
US8263780B2 (en) 2012-09-11
ES2410793T3 (es) 2013-07-03
KR101255879B1 (ko) 2013-04-17
WO2008062376A2 (en) 2008-05-29
EP2489662B1 (en) 2014-08-06
CN103087004A (zh) 2013-05-08
AU2007323042A1 (en) 2008-05-29
KR20090081009A (ko) 2009-07-27
JP4669564B2 (ja) 2011-04-13
US20100317867A1 (en) 2010-12-16
US20110201821A2 (en) 2011-08-18
IL198847A (en) 2015-07-30
TW200831474A (en) 2008-08-01
WO2008062376A3 (en) 2008-07-10
DK2489662T3 (da) 2014-10-20
EP2489662A1 (en) 2012-08-22
TWI460166B (zh) 2014-11-11
BRPI0718986A2 (pt) 2014-02-11

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