DK2031075T3 - M.tb åben læseramme Rv2659c og anvendelser deraf - Google Patents
M.tb åben læseramme Rv2659c og anvendelser derafInfo
- Publication number
- DK2031075T3 DK2031075T3 DK08017907.0T DK08017907T DK2031075T3 DK 2031075 T3 DK2031075 T3 DK 2031075T3 DK 08017907 T DK08017907 T DK 08017907T DK 2031075 T3 DK2031075 T3 DK 2031075T3
- Authority
- DK
- Denmark
- Prior art keywords
- deletions
- bcg
- isolates
- tuberculosis
- rv2659c
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
- C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/06—Antibacterial agents for tuberculosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Analytical Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Pulmonology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Data Exchanges In Wide-Area Networks (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Multicomponent Fibers (AREA)
- Door And Window Frames Mounted To Openings (AREA)
- Special Wing (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US9793698P | 1998-08-25 | 1998-08-25 | |
US09/318,191 US6291190B1 (en) | 1998-08-25 | 1999-05-25 | Molecular differences between species of the M. tuberculosis complex |
EP99939702A EP1108060B1 (en) | 1998-08-25 | 1999-08-10 | Molecular differences between species of the m. tuberculosis complex |
Publications (1)
Publication Number | Publication Date |
---|---|
DK2031075T3 true DK2031075T3 (da) | 2010-10-18 |
Family
ID=26793800
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK08017907.0T DK2031075T3 (da) | 1998-08-25 | 1999-08-10 | M.tb åben læseramme Rv2659c og anvendelser deraf |
DK99939702.9T DK1108060T3 (da) | 1998-08-25 | 1999-08-10 | Molekylære forskelle mellem arter af M. tuberculosis-komplekset |
DK08015511.2T DK2006395T3 (da) | 1998-08-25 | 1999-08-10 | M. tuberculosis åben læseramme RV2660c og anvendelser deraf |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK99939702.9T DK1108060T3 (da) | 1998-08-25 | 1999-08-10 | Molekylære forskelle mellem arter af M. tuberculosis-komplekset |
DK08015511.2T DK2006395T3 (da) | 1998-08-25 | 1999-08-10 | M. tuberculosis åben læseramme RV2660c og anvendelser deraf |
Country Status (9)
Country | Link |
---|---|
US (6) | US6291190B1 (da) |
EP (3) | EP2031075B1 (da) |
AT (3) | ATE473299T1 (da) |
AU (1) | AU5394699A (da) |
DE (3) | DE69942569D1 (da) |
DK (3) | DK2031075T3 (da) |
ES (1) | ES2343927T3 (da) |
PT (2) | PT2006395E (da) |
WO (1) | WO2000011214A1 (da) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6291190B1 (en) * | 1998-08-25 | 2001-09-18 | The Board Of Trustees Of The Leland Stanford Junior University | Molecular differences between species of the M. tuberculosis complex |
US20040018574A1 (en) * | 1998-08-25 | 2004-01-29 | Marcel Behr | Molecular differences between species of the M. tuberculosis complex |
FR2791067B1 (fr) * | 1999-03-16 | 2003-01-31 | Pasteur Institut | Sequence deletees chez m.bovis bcg/m.ou m.tuberculosis, procede de detection des mycobacteries utilisant ces sequences et vaccins |
ATE429245T1 (de) | 1999-05-04 | 2009-05-15 | Univ New Jersey Med | Durch mycobacterium tuberculosis und nicht durch bcg exprimierte proteine und ihre verwendung als diagnostische reagenzien und impfstoffe |
EP1377827A2 (en) * | 2001-04-10 | 2004-01-07 | NMI Naturwissenschaftliches und Medizinisches Institut an der Universität Tübingen in Reutlingen Stiftung Bürgerlichen Rechts | Method for determining analyte molecules in a sample |
US7758874B2 (en) * | 2002-02-19 | 2010-07-20 | Albert Einstein College Of Medicine Of Yeshiva University | Attenuated Mycobacterium tuberculosis vaccines |
WO2003070164A2 (en) * | 2002-02-19 | 2003-08-28 | Albert Einstein College Of Medicine Of Yeshiva University | Attenuated mycobacterium tuberculosis vaccines |
PT1338657E (pt) * | 2002-02-25 | 2007-06-21 | Pasteur Institut | Sequências especificamente deletadas do genoma de mycobacterium tuberculosis e o seu uso em diagnóstico e como vacinas. |
WO2003089462A2 (en) * | 2002-04-16 | 2003-10-30 | Jun Liu | Tuberculosis vaccines including recombinant bcg strains expressing alanine dehydrogenase, serine dehydratase and/or glutamine synthetase |
AU2003224313A1 (en) * | 2002-04-27 | 2003-11-17 | The Secretary Of State For Environment, Food And Rural Affairs | Mycobacterial antigens and uses thereof |
US20070105100A1 (en) * | 2003-04-28 | 2007-05-10 | Canon Kabushiki Kaisha | Process for assay of nucleic acids by competitive hybridization using a dna microarray |
ITRM20030411A1 (it) * | 2003-08-29 | 2005-02-28 | Consiglio Nazionale Ricerche | Uso di sequenze geniche specifiche di mycobacterium tubercolosis ecorrispondenti proteine per la diagnosi e la prevenzione di infezione tubercolare. |
WO2006060484A2 (en) * | 2004-12-01 | 2006-06-08 | Gene Therapy Systems, Inc. | Tuberculosis nucleic acids, polypeptides and immunogenic compositions |
CA2606962A1 (en) * | 2005-04-29 | 2006-11-09 | Fusion Antibodies Limited | Assays for diagnosis of tuberculosis and uses thereof |
EP1945755B1 (en) | 2005-07-26 | 2015-01-14 | Rutgers, the State University of New Jersey | Antibody profiles characteristic of tuberculosis state |
DK1922415T3 (da) * | 2005-09-05 | 2014-03-10 | Bio Rad Innovations | Anvendelse af både rd9 og is6110 som nukleinsyretargets til diagnose af tuberkulose, og tilvejebringelse af multiplex-egnede is6110- og rd9-targets |
US20090148870A1 (en) * | 2006-05-18 | 2009-06-11 | Ericson Daniel G | Rapid Detection of Mycobacterium Tuberculosis and Antimicrobial Drug Resistance |
BRPI0604958B1 (pt) * | 2006-11-23 | 2022-05-17 | Fundação Oswaldo Cruz | Kit para distinção de mycobacterium tuberculosis, m. bovis, m. bovis bcg em uma amostra, e, método para distinguir mycobacterium tuberculosis, m. bovis, m. bovis bcg |
CN101661044B (zh) * | 2008-08-27 | 2013-10-16 | 复旦大学附属华山医院 | 一种结核病诊断试剂及试剂盒 |
WO2010030049A1 (en) * | 2008-09-12 | 2010-03-18 | Lg Life Sciences, Ltd. | Composition for detection of m. tuberculosis complex or mycobacteria genus and simultaneous detection method for m. tuberculosis complex and mycobacteria genus with multiplex real time pcr using the same |
GB0903168D0 (en) | 2009-02-25 | 2009-04-08 | Fusion Antibodies Ltd | Diagnostic method and kit |
CN102713629B (zh) | 2009-11-20 | 2016-02-24 | 俄勒冈健康科学大学 | 用于检测结核分枝杆菌感染的方法 |
KR101158647B1 (ko) * | 2010-05-27 | 2012-06-26 | 울산대학교 산학협력단 | 이중 실시간 중합효소연쇄반응법과 융해곡선분석을 이용하는 결핵균과 항산성비결핵균의 검출 방법 |
US9663758B2 (en) * | 2013-03-12 | 2017-05-30 | Wisconsin Alumni Research Foundation | Global gene regulators (GGR) as vaccine candidates against paratuberculosis |
MX2019003288A (es) * | 2016-09-22 | 2019-11-05 | Pace Diagnostics Inc | Proteínas de mycobacterium tuberculosis en pruebas diagnósticas y dispositivos para la detección y diagnóstico de la tuberculosis. |
KR102247643B1 (ko) * | 2019-11-01 | 2021-05-03 | 바이오파크진단 주식회사 | 결핵균 및 비결핵항산균을 검출하기 위한 2단계 진단방법 및 키트 |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5591632A (en) | 1987-03-02 | 1997-01-07 | Beth Israel Hospital | Recombinant BCG |
JP3011939B2 (ja) * | 1987-03-02 | 2000-02-21 | ホワイトヘツド・インスチチユート・フオー・バイオメデイカル・リサーチ | 組換えミコバクテリア・ワクチン |
US5143854A (en) | 1989-06-07 | 1992-09-01 | Affymax Technologies N.V. | Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof |
PH27357A (en) * | 1989-09-22 | 1993-06-21 | Fujisawa Pharmaceutical Co | Pyrazole derivatives and pharmaceutical compositions comprising the same |
EP0499003A1 (en) * | 1991-02-14 | 1992-08-19 | N.V. Innogenetics S.A. | Polypeptides and peptides, particularly recombinant polypeptides and peptides, nucleic acids coding for the same and use of these polypeptides and peptides in the diagnosis of tuberculosis |
DK79793D0 (da) * | 1993-07-02 | 1993-07-02 | Statens Seruminstitut | Diagnostic test |
US5807522A (en) | 1994-06-17 | 1998-09-15 | The Board Of Trustees Of The Leland Stanford Junior University | Methods for fabricating microarrays of biological samples |
US5700683A (en) | 1995-02-17 | 1997-12-23 | Pathogenesis Corporation | Virulence-attenuating genetic deletions deleted from mycobacterium BCG |
WO1996027129A1 (en) | 1995-02-28 | 1996-09-06 | Ehrenkranz Joel R L | Rapid, self-performing tsh immunoassay |
US5686597A (en) | 1995-06-06 | 1997-11-11 | Incyte Pharmaceuticals, Inc. | Thrombin receptor homolog |
CA2276491C (en) * | 1996-12-31 | 2008-01-22 | New York University | Early detection of mycobacterial disease |
US20040013685A1 (en) * | 1997-11-10 | 2004-01-22 | Peter Andersen | Nucleic acid fragments and polypeptide fragments derived from M. tuberculosis |
US6291190B1 (en) * | 1998-08-25 | 2001-09-18 | The Board Of Trustees Of The Leland Stanford Junior University | Molecular differences between species of the M. tuberculosis complex |
CA2378763A1 (en) * | 1999-07-13 | 2001-01-18 | Statens Serum Institut | Tuberculosis vaccine and diagnostics based on the mycobacterium tuberculosis esat-6 gene family |
-
1999
- 1999-05-25 US US09/318,191 patent/US6291190B1/en not_active Expired - Fee Related
- 1999-08-10 AT AT08017907T patent/ATE473299T1/de not_active IP Right Cessation
- 1999-08-10 WO PCT/US1999/017939 patent/WO2000011214A1/en active Application Filing
- 1999-08-10 DK DK08017907.0T patent/DK2031075T3/da active
- 1999-08-10 AT AT08015511T patent/ATE507308T1/de active
- 1999-08-10 DK DK99939702.9T patent/DK1108060T3/da active
- 1999-08-10 EP EP08017907A patent/EP2031075B1/en not_active Expired - Lifetime
- 1999-08-10 ES ES99939702T patent/ES2343927T3/es not_active Expired - Lifetime
- 1999-08-10 DE DE69942569T patent/DE69942569D1/de not_active Expired - Lifetime
- 1999-08-10 DE DE69943401T patent/DE69943401D1/de not_active Expired - Lifetime
- 1999-08-10 DK DK08015511.2T patent/DK2006395T3/da active
- 1999-08-10 EP EP08015511A patent/EP2006395B1/en not_active Expired - Lifetime
- 1999-08-10 DE DE69942310T patent/DE69942310D1/de not_active Expired - Lifetime
- 1999-08-10 PT PT08015511T patent/PT2006395E/pt unknown
- 1999-08-10 EP EP99939702A patent/EP1108060B1/en not_active Expired - Lifetime
- 1999-08-10 AT AT99939702T patent/ATE466100T1/de active
- 1999-08-10 PT PT99939702T patent/PT1108060E/pt unknown
- 1999-08-10 AU AU53946/99A patent/AU5394699A/en not_active Abandoned
-
2001
- 2001-06-27 US US09/894,844 patent/US6686166B2/en not_active Expired - Lifetime
-
2003
- 2003-08-21 US US10/647,089 patent/US20040063923A1/en not_active Abandoned
-
2005
- 2005-06-01 US US11/143,401 patent/US7364740B2/en not_active Expired - Lifetime
-
2008
- 2008-03-14 US US12/049,063 patent/US7700118B2/en not_active Expired - Fee Related
-
2010
- 2010-04-02 US US12/753,330 patent/US20110206715A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
DE69942569D1 (de) | 2010-08-19 |
WO2000011214B1 (en) | 2000-04-13 |
EP1108060A1 (en) | 2001-06-20 |
US6291190B1 (en) | 2001-09-18 |
ATE466100T1 (de) | 2010-05-15 |
ATE507308T1 (de) | 2011-05-15 |
ATE473299T1 (de) | 2010-07-15 |
US20020176873A1 (en) | 2002-11-28 |
PT2006395E (pt) | 2011-07-13 |
PT1108060E (pt) | 2010-08-04 |
EP1108060B1 (en) | 2010-04-28 |
EP2031075A1 (en) | 2009-03-04 |
ES2343927T3 (es) | 2010-08-12 |
AU5394699A (en) | 2000-03-14 |
US20040063923A1 (en) | 2004-04-01 |
US20080254052A1 (en) | 2008-10-16 |
EP2006395B1 (en) | 2011-04-27 |
WO2000011214A1 (en) | 2000-03-02 |
US20110206715A1 (en) | 2011-08-25 |
DK2006395T3 (da) | 2011-07-18 |
US7700118B2 (en) | 2010-04-20 |
US6686166B2 (en) | 2004-02-03 |
DE69942310D1 (de) | 2010-06-10 |
US20060002953A1 (en) | 2006-01-05 |
EP2006395A1 (en) | 2008-12-24 |
EP2031075B1 (en) | 2010-07-07 |
US7364740B2 (en) | 2008-04-29 |
DE69943401D1 (de) | 2011-06-09 |
DK1108060T3 (da) | 2010-08-16 |
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