DK200586A - APPLICATION OF PYRIDINONE COMPOUNDS WITH ANTITHROMOBOTIC EFFECT IN MEDICINAL PRODUCTS - Google Patents

APPLICATION OF PYRIDINONE COMPOUNDS WITH ANTITHROMOBOTIC EFFECT IN MEDICINAL PRODUCTS Download PDF

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Publication number
DK200586A
DK200586A DK200586A DK200586A DK200586A DK 200586 A DK200586 A DK 200586A DK 200586 A DK200586 A DK 200586A DK 200586 A DK200586 A DK 200586A DK 200586 A DK200586 A DK 200586A
Authority
DK
Denmark
Prior art keywords
antithromobotic
application
effect
medicinal products
pyridinone compounds
Prior art date
Application number
DK200586A
Other languages
Danish (da)
Other versions
DK200586D0 (en
Inventor
Juergen Daemmgen
Helmut Ballhause
Walter Haarman
Joachim Heider
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of DK200586D0 publication Critical patent/DK200586D0/en
Publication of DK200586A publication Critical patent/DK200586A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/24—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
    • C07D239/88—Oxygen atoms
    • C07D239/91—Oxygen atoms with aryl or aralkyl radicals attached in position 2 or 3

Description

alkylengruppe, der er substitueret i yderpositionen med en methoxyphenyl-, dimethoxyphenyl eller en methylphe-noxygruppe; og R3 betegner et hydrogenatom eller en methoxygruppe, deres antipoder samt fysiologisk acceptable syreadditionssalte med uorganiske eller organiske syrer til behandling af og profylakse for thrombo-emboliske sygdomme til profylakse for arteriosklerose og til metastaseprofylakse .alkylene group substituted in the outer position by a methoxyphenyl, dimethoxyphenyl or a methylphenoxy group; and R3 represents a hydrogen atom or a methoxy group, their antipodes as well as physiologically acceptable acid addition salts with inorganic or organic acids for the treatment and prophylaxis of thromboembolic diseases for prophylaxis of arteriosclerosis and for metastasis prophylaxis.

DK200586A 1985-05-03 1986-05-01 APPLICATION OF PYRIDINONE COMPOUNDS WITH ANTITHROMOBOTIC EFFECT IN MEDICINAL PRODUCTS DK200586A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3515882 1985-05-03
DE19853515882 DE3515882A1 (en) 1985-05-03 1985-05-03 MEDICINAL PRODUCTS CONTAINING PYRIDINONE WITH ANTITHROMBOTIC EFFECTS AND METHOD FOR THE PRODUCTION THEREOF

Publications (2)

Publication Number Publication Date
DK200586D0 DK200586D0 (en) 1986-05-01
DK200586A true DK200586A (en) 1986-11-04

Family

ID=6269707

Family Applications (1)

Application Number Title Priority Date Filing Date
DK200586A DK200586A (en) 1985-05-03 1986-05-01 APPLICATION OF PYRIDINONE COMPOUNDS WITH ANTITHROMOBOTIC EFFECT IN MEDICINAL PRODUCTS

Country Status (6)

Country Link
EP (1) EP0210342A2 (en)
JP (1) JPS61254524A (en)
AU (1) AU5706486A (en)
DE (1) DE3515882A1 (en)
DK (1) DK200586A (en)
ZA (1) ZA863304B (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3533542B2 (en) * 1994-03-08 2004-05-31 株式会社大塚製薬工場 Phosphonic acid diester derivatives
US6642244B2 (en) 2001-03-16 2003-11-04 Bristol-Myers Squibb Co. Pyrazolopyridopyrimidine inhibitors of cGMP phosphodiesterase
US7846915B2 (en) 2004-10-20 2010-12-07 Resverlogix Corporation Stilbenes and chalcones for the prevention and treatment of cardiovascular diseases
CN101641339B (en) 2007-02-01 2013-07-17 雷斯韦洛吉克斯公司 Compounds for the prevention and treatment of cardiovascular diseases
CN101531638B (en) * 2008-03-13 2011-12-28 中国科学院广州生物医药与健康研究院 Compound used as a regulator of estrogen-related receptor and applications thereof
KR101629356B1 (en) 2008-06-26 2016-06-13 리스버로직스 코퍼레이션 Methods of preparing quinazolinone derivatives
CN101628913B (en) 2008-07-18 2013-01-23 中国科学院广州生物医药与健康研究院 Compound as estrogen-related receptor modulator and application thereof
AU2010204106B2 (en) 2009-01-08 2014-05-08 Resverlogix Corp. Compounds for the prevention and treatment of cardiovascular disease
MX2021012876A (en) 2009-03-18 2022-06-23 Resverlogix Corp Novel anti-inflammatory agents.
ES2821018T3 (en) 2009-04-22 2021-04-23 Resverlogix Corp New anti-inflammatory agents
PT2773354T (en) 2011-11-01 2019-07-17 Resverlogix Corp Oral immediate release formulations for substituted quinazolinones
WO2014080291A2 (en) 2012-11-21 2014-05-30 Rvx Therapeutics Inc. Biaryl derivatives as bromodomain inhibitors
US9073878B2 (en) 2012-11-21 2015-07-07 Zenith Epigenetics Corp. Cyclic amines as bromodomain inhibitors
AU2013365926B9 (en) 2012-12-21 2019-01-17 Zenith Epigenetics Ltd. Novel heterocyclic compounds as bromodomain inhibitors
US10111885B2 (en) 2015-03-13 2018-10-30 Resverlogix Corp. Compositions and therapeutic methods for the treatment of complement-associated diseases

Also Published As

Publication number Publication date
AU5706486A (en) 1986-11-06
EP0210342A2 (en) 1987-02-04
ZA863304B (en) 1988-01-27
DK200586D0 (en) 1986-05-01
JPS61254524A (en) 1986-11-12
DE3515882A1 (en) 1986-11-06

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