DK1979378T3 - Ny samling af HCDR3 områder og anvendelser derfor - Google Patents

Ny samling af HCDR3 områder og anvendelser derfor

Info

Publication number
DK1979378T3
DK1979378T3 DK06851829.9T DK06851829T DK1979378T3 DK 1979378 T3 DK1979378 T3 DK 1979378T3 DK 06851829 T DK06851829 T DK 06851829T DK 1979378 T3 DK1979378 T3 DK 1979378T3
Authority
DK
Denmark
Prior art keywords
hcdr3
areas
applications
new collection
collection
Prior art date
Application number
DK06851829.9T
Other languages
English (en)
Inventor
Markus Enzelberger
Stefanie Thiel
Josef Prassler
Stefanie Urlinger
Christine Rothe
Original Assignee
Morphosys Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Morphosys Ag filed Critical Morphosys Ag
Application granted granted Critical
Publication of DK1979378T3 publication Critical patent/DK1979378T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DK06851829.9T 2005-12-20 2006-12-15 Ny samling af HCDR3 områder og anvendelser derfor DK1979378T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US75163305P 2005-12-20 2005-12-20
PCT/IB2006/004301 WO2008053275A2 (en) 2005-12-20 2006-12-15 Novel collection of hcdr3 regions and uses therefor

Publications (1)

Publication Number Publication Date
DK1979378T3 true DK1979378T3 (da) 2012-10-29

Family

ID=39273832

Family Applications (1)

Application Number Title Priority Date Filing Date
DK06851829.9T DK1979378T3 (da) 2005-12-20 2006-12-15 Ny samling af HCDR3 områder og anvendelser derfor

Country Status (15)

Country Link
US (1) US8273688B2 (da)
EP (1) EP1979378B1 (da)
JP (1) JP5405831B2 (da)
KR (1) KR20080080653A (da)
CN (1) CN101389655B (da)
AU (1) AU2006350452B2 (da)
CA (1) CA2634387C (da)
DK (1) DK1979378T3 (da)
ES (1) ES2394722T3 (da)
IL (1) IL192315A0 (da)
MX (1) MX2008008220A (da)
NO (1) NO20083171L (da)
NZ (1) NZ569359A (da)
WO (1) WO2008053275A2 (da)
ZA (1) ZA200806016B (da)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8288322B2 (en) 2000-04-17 2012-10-16 Dyax Corp. Methods of constructing libraries comprising displayed and/or expressed members of a diverse family of peptides, polypeptides or proteins and the novel libraries
US7754208B2 (en) * 2001-01-17 2010-07-13 Trubion Pharmaceuticals, Inc. Binding domain-immunoglobulin fusion proteins
US20030133939A1 (en) 2001-01-17 2003-07-17 Genecraft, Inc. Binding domain-immunoglobulin fusion proteins
US7829084B2 (en) * 2001-01-17 2010-11-09 Trubion Pharmaceuticals, Inc. Binding constructs and methods for use thereof
US20040067532A1 (en) 2002-08-12 2004-04-08 Genetastix Corporation High throughput generation and affinity maturation of humanized antibody
HUE026303T2 (hu) 2005-07-25 2016-06-28 Emergent Product Dev Seattle B-sejt csökkentés CD37-specifikus és CD20-specifikus kapcsoló molekulák alkalmazásával
EP2418223A3 (en) * 2006-06-12 2013-01-16 Emergent Product Development Seattle, LLC Single-chain multivalent binding proteins with effector function
US8877688B2 (en) 2007-09-14 2014-11-04 Adimab, Llc Rationally designed, synthetic antibody libraries and uses therefor
EP3753947A1 (en) 2007-09-14 2020-12-23 Adimab, LLC Rationally designed, synthetic antibody libraries and uses therefor
EP2098536A1 (en) 2008-03-05 2009-09-09 4-Antibody AG Isolation and identification of antigen- or ligand-specific binding proteins
WO2009114815A1 (en) 2008-03-13 2009-09-17 Dyax Corp Libraries of genetic packages comprising novel hc cdr3 designs
DK2132228T3 (da) 2008-04-11 2011-10-10 Emergent Product Dev Seattle CD37-immunterapeutisk middel og kombination med bifunktionelt kemoterapeutisk middel deraf
CA2968164C (en) 2008-04-24 2019-08-20 Dyax Corp. Libraries of genetic packages comprising novel hc cdr1, cdr2, and cdr3 and novel lc cdr1, cdr2, and cdr3 designs
SG175407A1 (en) 2009-05-29 2011-11-28 Morphosys Ag A collection and methods for its use
JP2013504602A (ja) * 2009-09-14 2013-02-07 ダイアックス コーポレーション 新しく設計したｈｃｃｄｒ３を含む遺伝子パッケージライブラリー
CN103282560B (zh) 2010-07-16 2016-08-03 阿迪马布有限责任公司 抗体文库
DK2640742T3 (da) 2010-11-19 2018-12-03 Morphosys Ag Samling af antistofsekvenser og disses anvendelser
CN108367004B (zh) 2015-09-21 2022-09-13 阿帕特夫研究和发展有限公司 Cd3结合多肽
CN105274630A (zh) * 2015-11-25 2016-01-27 苏州泓迅生物科技有限公司 基于组合合成技术合成可控的人源化抗体库的方法与应用
JP6959260B2 (ja) * 2016-01-19 2021-11-02 ズムトール バイオロジクス、インコーポレイテッド 合成抗体ライブラリーを作製する方法、前記ライブラリー、及びその適用
EP3293293A1 (en) 2016-09-08 2018-03-14 Italfarmaco SpA Hc-cdr3-only libraries with reduced combinatorial redundancy and optimized loop length distribution

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0859841B1 (en) 1995-08-18 2002-06-19 MorphoSys AG Protein/(poly)peptide libraries
US6696248B1 (en) * 1995-08-18 2004-02-24 Morphosys Ag Protein/(poly)peptide libraries
EP1990409A3 (en) * 1999-07-20 2011-05-18 MorphoSys AG Bacteriophage
DE60144063D1 (de) * 2000-12-18 2011-03-31 Dyax Corp Gerichtete bibliotheken die genetisch verpackt sind

Also Published As

Publication number Publication date
CN101389655A (zh) 2009-03-18
ES2394722T3 (es) 2013-02-05
AU2006350452A1 (en) 2008-05-08
CA2634387A1 (en) 2008-05-08
CA2634387C (en) 2015-11-24
NZ569359A (en) 2011-11-25
EP1979378A2 (en) 2008-10-15
MX2008008220A (es) 2009-03-04
JP2009519727A (ja) 2009-05-21
ZA200806016B (en) 2009-07-29
WO2008053275A2 (en) 2008-05-08
WO2008053275A3 (en) 2008-08-21
CN101389655B (zh) 2013-05-22
EP1979378B1 (en) 2012-07-25
AU2006350452B2 (en) 2012-10-25
IL192315A0 (en) 2008-12-29
US20090088346A1 (en) 2009-04-02
KR20080080653A (ko) 2008-09-04
JP5405831B2 (ja) 2014-02-05
US8273688B2 (en) 2012-09-25
NO20083171L (no) 2008-08-27

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