DK1896401T3 - Syntese af umættede sulfider, sulfoner, sulfoxider og sulfonamider - Google Patents
Syntese af umættede sulfider, sulfoner, sulfoxider og sulfonamiderInfo
- Publication number
- DK1896401T3 DK1896401T3 DK06736103.0T DK06736103T DK1896401T3 DK 1896401 T3 DK1896401 T3 DK 1896401T3 DK 06736103 T DK06736103 T DK 06736103T DK 1896401 T3 DK1896401 T3 DK 1896401T3
- Authority
- DK
- Denmark
- Prior art keywords
- sulfonamides
- sulfoxides
- sulfones
- synthesis
- unsaturated sulfides
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
- C07C323/24—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/29—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C315/00—Preparation of sulfones; Preparation of sulfoxides
- C07C315/02—Preparation of sulfones; Preparation of sulfoxides by formation of sulfone or sulfoxide groups by oxidation of sulfides, or by formation of sulfone groups by oxidation of sulfoxides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C315/00—Preparation of sulfones; Preparation of sulfoxides
- C07C315/04—Preparation of sulfones; Preparation of sulfoxides by reactions not involving the formation of sulfone or sulfoxide groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/02—Sulfones; Sulfoxides having sulfone or sulfoxide groups bound to acyclic carbon atoms
- C07C317/10—Sulfones; Sulfoxides having sulfone or sulfoxide groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/16—Sulfones; Sulfoxides having sulfone or sulfoxide groups and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C317/18—Sulfones; Sulfoxides having sulfone or sulfoxide groups and singly-bound oxygen atoms bound to the same carbon skeleton with sulfone or sulfoxide groups bound to acyclic carbon atoms of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/26—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
- C07C317/28—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to acyclic carbon atoms of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
- C07C319/14—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/01—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and halogen atoms, or nitro or nitroso groups bound to the same carbon skeleton
- C07C323/02—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and halogen atoms, or nitro or nitroso groups bound to the same carbon skeleton having sulfur atoms of thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/07—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and halogen atoms, or nitro or nitroso groups bound to the same carbon skeleton having sulfur atoms of thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/10—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C323/11—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/16—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US65620405P | 2005-02-25 | 2005-02-25 | |
PCT/US2006/006698 WO2006091870A2 (en) | 2005-02-25 | 2006-02-24 | Unsaturated sulfides, sulfones, sulfoxides and sulfonamides synthesis |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1896401T3 true DK1896401T3 (da) | 2013-06-17 |
Family
ID=36928071
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK06736103.0T DK1896401T3 (da) | 2005-02-25 | 2006-02-24 | Syntese af umættede sulfider, sulfoner, sulfoxider og sulfonamider |
Country Status (11)
Country | Link |
---|---|
US (1) | US8143453B2 (da) |
EP (1) | EP1896401B1 (da) |
AU (1) | AU2006216544B2 (da) |
CA (1) | CA2599169C (da) |
DK (1) | DK1896401T3 (da) |
ES (1) | ES2417135T3 (da) |
IL (1) | IL185400A (da) |
PL (1) | PL1896401T3 (da) |
PT (1) | PT1896401E (da) |
SI (1) | SI1896401T1 (da) |
WO (1) | WO2006091870A2 (da) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2559187C (en) * | 2004-03-16 | 2014-02-11 | Temple University - Of The Commonwealth System Of Higher Education | Substituted phenoxy- and phenylthio- derivatives for treating proliferative disorders |
US8664272B2 (en) | 2006-08-30 | 2014-03-04 | Temple University—Of the Commonwealth System of Higher Education | Composition and methods for the treatment of myelodysplastic syndrome and acute myeloid leukemia |
TWI395593B (zh) | 2008-03-06 | 2013-05-11 | Halozyme Inc | 可活化的基質降解酵素之活體內暫時性控制 |
GB201010359D0 (en) | 2010-06-21 | 2010-08-04 | Univ Nottingham | Compounds for treating proliferative disorders |
WO2013056079A1 (en) * | 2011-10-13 | 2013-04-18 | The Johns Hopkins University | High affinity beta lactamase inhibitors |
JP6348904B2 (ja) * | 2012-09-20 | 2018-06-27 | テンプル・ユニバーシティ−オブ・ザ・コモンウェルス・システム・オブ・ハイアー・エデュケイションTemple University−Of The Commonwealth System Of Higher Education | 置換アルキルジアリール誘導体、その製造方法及び使用 |
US10383831B2 (en) | 2015-08-03 | 2019-08-20 | Temple University—Of the Commonwealth System of Higher Education | 2,4,6-trialkoxystryl aryl sulfones, sulfonamides and carboxamides, and methods of preparation and use |
CN109320443B (zh) | 2017-08-01 | 2021-02-26 | 财团法人工业技术研究院 | 化合物的制备方法及包含其的聚合物的制备方法 |
CN110981770A (zh) * | 2019-12-30 | 2020-04-10 | 武汉九州钰民医药科技有限公司 | 制备抗肿瘤新药Rigosertib的方法 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4246263A (en) * | 1979-10-15 | 1981-01-20 | Pfizer Inc. | Antiinflammatory and immunoregulatory pyrimidines, their method of use and pharmaceutical compositions |
IL135438A (en) * | 1997-10-03 | 2005-12-18 | Univ Temple | Pharmaceutical compositions containing styrl sulfones and some such novel styryl sulfone compounds with anticancer activity |
US6548553B2 (en) | 1997-10-03 | 2003-04-15 | Temple University-Of The Commonwealth System Of Higher Education | Styryl sulfone anticancer agents |
US6201154B1 (en) | 1999-03-31 | 2001-03-13 | Temple University-Of The Commonwealth Of Higher Education | Z-styryl sulfone anticancer agents |
US6762207B1 (en) | 1999-04-02 | 2004-07-13 | Temple University - Of The Commonwealth System Of Higher Education | (E)-styryl sulfone anticancer agents |
US6767926B1 (en) | 1999-10-12 | 2004-07-27 | Temple University - Of The Commonwealth System Of Higher Education | Method for protecting normal cells from cytotoxicity of chemotherapeutic agents |
US6486210B2 (en) * | 2000-04-14 | 2002-11-26 | Temple University—Of the Commonwealth System of Higher Education | Substituted styryl benzylsulfones for treating proliferative disorders |
US6541475B2 (en) | 2000-04-14 | 2003-04-01 | Temple University - Of The Commonwealth System Of Higher Education | α, β-unsaturated sulfones for treating proliferative disorders |
JP4302986B2 (ja) | 2001-02-28 | 2009-07-29 | テンプル・ユニバーシティ−オブ・ザ・コモンウェルス・システム・オブ・ハイアー・エデュケイション | 細胞及び組織をα,β不飽和アリールスルホンにより電離放射線から防護する方法 |
CN1173903C (zh) * | 2001-07-13 | 2004-11-03 | 中国科学院上海有机化学研究所 | 一种高效的含氮或含氧三元小环化合物的开环方法 |
-
2006
- 2006-02-24 EP EP06736103.0A patent/EP1896401B1/en active Active
- 2006-02-24 US US11/884,601 patent/US8143453B2/en active Active
- 2006-02-24 SI SI200631592T patent/SI1896401T1/sl unknown
- 2006-02-24 PL PL06736103T patent/PL1896401T3/pl unknown
- 2006-02-24 WO PCT/US2006/006698 patent/WO2006091870A2/en active Application Filing
- 2006-02-24 PT PT67361030T patent/PT1896401E/pt unknown
- 2006-02-24 DK DK06736103.0T patent/DK1896401T3/da active
- 2006-02-24 ES ES06736103T patent/ES2417135T3/es active Active
- 2006-02-24 AU AU2006216544A patent/AU2006216544B2/en active Active
- 2006-02-24 CA CA2599169A patent/CA2599169C/en active Active
-
2007
- 2007-08-20 IL IL185400A patent/IL185400A/en active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
CA2599169C (en) | 2013-10-22 |
EP1896401A4 (en) | 2010-07-14 |
AU2006216544A1 (en) | 2006-08-31 |
US20090124828A1 (en) | 2009-05-14 |
PT1896401E (pt) | 2013-07-17 |
WO2006091870A2 (en) | 2006-08-31 |
EP1896401B1 (en) | 2013-04-10 |
PL1896401T3 (pl) | 2014-03-31 |
ES2417135T3 (es) | 2013-08-06 |
IL185400A (en) | 2014-07-31 |
EP1896401A2 (en) | 2008-03-12 |
AU2006216544B2 (en) | 2012-04-05 |
SI1896401T1 (sl) | 2013-07-31 |
US8143453B2 (en) | 2012-03-27 |
WO2006091870A3 (en) | 2007-01-18 |
IL185400A0 (en) | 2008-02-09 |
CA2599169A1 (en) | 2006-08-31 |
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