DK1877403T3 - Mono-lysinsalte af azolforbindelser - Google Patents

Mono-lysinsalte af azolforbindelser

Info

Publication number
DK1877403T3
DK1877403T3 DK06746245.7T DK06746245T DK1877403T3 DK 1877403 T3 DK1877403 T3 DK 1877403T3 DK 06746245 T DK06746245 T DK 06746245T DK 1877403 T3 DK1877403 T3 DK 1877403T3
Authority
DK
Denmark
Prior art keywords
mono
azole compounds
lysine salts
lysine
salts
Prior art date
Application number
DK06746245.7T
Other languages
English (en)
Inventor
Michael G Fakes
Yadagiri R Pendri
Susanne Kiau
Blisse Vakkalagadda
Qi Gao
Chung-Pin H Chen
Original Assignee
Eisai R&D Man Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eisai R&D Man Co Ltd filed Critical Eisai R&D Man Co Ltd
Application granted granted Critical
Publication of DK1877403T3 publication Critical patent/DK1877403T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/26Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having more than one amino group bound to the carbon skeleton, e.g. lysine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02Phosphorus compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02Phosphorus compounds
    • C07F9/06Phosphorus compounds without P—C bonds
    • C07F9/08Esters of oxyacids of phosphorus
    • C07F9/09Esters of phosphoric acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6558Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
    • C07F9/65583Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system each of the hetero rings containing nitrogen as ring hetero atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6558Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
    • C07F9/65586Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system at least one of the hetero rings does not contain nitrogen as ring hetero atom
DK06746245.7T 2005-05-03 2006-05-01 Mono-lysinsalte af azolforbindelser DK1877403T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US67693205P 2005-05-03 2005-05-03
PCT/JP2006/309435 WO2006118351A1 (en) 2005-05-03 2006-05-01 Mono-lysine salts of azole compounds

Publications (1)

Publication Number Publication Date
DK1877403T3 true DK1877403T3 (da) 2011-05-09

Family

ID=36910951

Family Applications (1)

Application Number Title Priority Date Filing Date
DK06746245.7T DK1877403T3 (da) 2005-05-03 2006-05-01 Mono-lysinsalte af azolforbindelser

Country Status (34)

Country Link
US (1) US20060264406A1 (da)
EP (1) EP1877403B1 (da)
JP (1) JP4015691B1 (da)
KR (1) KR100887044B1 (da)
CN (1) CN101213193B (da)
AR (1) AR053862A1 (da)
AT (1) ATE503753T1 (da)
AU (1) AU2006241694B2 (da)
BR (1) BRPI0610423B8 (da)
CA (1) CA2606185C (da)
CY (1) CY1111569T1 (da)
DE (1) DE602006020998D1 (da)
DK (1) DK1877403T3 (da)
EC (1) ECSP077812A (da)
ES (1) ES2361768T3 (da)
HK (1) HK1117502A1 (da)
HR (1) HRP20110467T1 (da)
IL (1) IL187059A (da)
JO (1) JO2691B1 (da)
MX (1) MX2007013605A (da)
MY (1) MY138095A (da)
NO (1) NO20075541L (da)
NZ (1) NZ563092A (da)
PE (1) PE20071423A1 (da)
PL (1) PL1877403T3 (da)
PT (1) PT1877403E (da)
RS (1) RS51779B (da)
RU (1) RU2399625C2 (da)
SA (1) SA06270126B1 (da)
SI (1) SI1877403T1 (da)
TW (1) TWI363630B (da)
UY (1) UY29507A1 (da)
WO (1) WO2006118351A1 (da)
ZA (1) ZA200709127B (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101337127B1 (ko) 2005-12-20 2013-12-05 에자이 알앤드디 매니지먼트 가부시키가이샤 수용성 아졸 프로드러그의 제조 방법
ES2351365T3 (es) 2006-02-22 2011-02-03 EISAI R&D MANAGEMENT CO., LTD. Composición farmacéutica estabilizada.
CN105287403A (zh) * 2014-08-02 2016-02-03 陕西合成药业股份有限公司 一种泊沙康唑前体药物的冻干组合物及其制备方法和用途
CN106432338A (zh) * 2015-08-08 2017-02-22 陕西合成药业股份有限公司 泊沙康唑衍生物、合成和在长效制剂中的用途
US11324728B2 (en) 2017-11-28 2022-05-10 Seren Pharmaceuticals Inc. Dosing regimens for the treatment of fungal infections
CN110938093B (zh) * 2018-09-21 2022-08-19 华创合成制药股份有限公司 一种泊沙康唑磷酸酯单胆碱盐及其制备方法和用途

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT741737E (pt) * 1994-01-24 2000-04-28 Janssen Pharmaceutica Nv Antifungicos do tipo azole soluveis em agua
NZ270418A (en) * 1994-02-07 1997-09-22 Eisai Co Ltd Polycyclic triazole & imidazole derivatives, antifungal compositions
US5883097A (en) * 1998-04-16 1999-03-16 Schering Corporation Soluble azole antifungal salt
US6265584B1 (en) * 1998-05-22 2001-07-24 Bristol-Myers Squibb Company Water soluble prodrugs of azole compounds
WO2000030655A1 (en) * 1998-11-20 2000-06-02 Bristol-Myers Squibb Company Water soluble prodrugs of azole compounds
US6235728B1 (en) * 1999-02-19 2001-05-22 Bristol-Myers Squibb Company Water-soluble prodrugs of azole compounds
US6362172B2 (en) * 2000-01-20 2002-03-26 Bristol-Myers Squibb Company Water soluble prodrugs of azole compounds
US6448401B1 (en) * 2000-11-20 2002-09-10 Bristol-Myers Squibb Company Process for water soluble azole compounds

Also Published As

Publication number Publication date
HRP20110467T1 (hr) 2011-07-31
HK1117502A1 (en) 2009-01-16
UY29507A1 (es) 2006-11-30
BRPI0610423B8 (pt) 2021-05-25
CN101213193A (zh) 2008-07-02
IL187059A (en) 2012-08-30
MY138095A (en) 2009-04-30
NO20075541L (no) 2007-11-28
ES2361768T3 (es) 2011-06-22
TW200722093A (en) 2007-06-16
ZA200709127B (en) 2008-07-30
EP1877403A1 (en) 2008-01-16
WO2006118351A1 (en) 2006-11-09
JP4015691B1 (ja) 2007-11-28
PE20071423A1 (es) 2006-12-17
TWI363630B (en) 2012-05-11
MX2007013605A (es) 2008-01-24
CN101213193B (zh) 2011-02-02
AU2006241694B2 (en) 2011-10-20
AR053862A1 (es) 2007-05-23
BRPI0610423A2 (pt) 2010-06-22
NZ563092A (en) 2010-06-25
CY1111569T1 (el) 2015-10-07
ECSP077812A (es) 2008-01-23
AU2006241694A1 (en) 2006-11-09
US20060264406A1 (en) 2006-11-23
RS51779B (en) 2011-12-31
RU2007140788A (ru) 2009-06-10
IL187059A0 (en) 2008-02-09
KR20070088460A (ko) 2007-08-29
DE602006020998D1 (de) 2011-05-12
EP1877403B1 (en) 2011-03-30
RU2399625C2 (ru) 2010-09-20
JP2008544948A (ja) 2008-12-11
PT1877403E (pt) 2011-05-31
SA06270126B1 (ar) 2009-09-02
JO2691B1 (en) 2013-03-03
CA2606185C (en) 2012-08-28
KR100887044B1 (ko) 2009-03-04
ATE503753T1 (de) 2011-04-15
PL1877403T3 (pl) 2011-08-31
CA2606185A1 (en) 2006-11-09
BRPI0610423B1 (pt) 2020-11-10
SI1877403T1 (sl) 2011-05-31

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