DK1833462T3 - Farmaceutisk fremstillingsfremgangsmåde til varmesteriliserede glucocorticoidsuspensioner - Google Patents

Farmaceutisk fremstillingsfremgangsmåde til varmesteriliserede glucocorticoidsuspensioner

Info

Publication number
DK1833462T3
DK1833462T3 DK05851715.2T DK05851715T DK1833462T3 DK 1833462 T3 DK1833462 T3 DK 1833462T3 DK 05851715 T DK05851715 T DK 05851715T DK 1833462 T3 DK1833462 T3 DK 1833462T3
Authority
DK
Denmark
Prior art keywords
pharmaceutical preparation
heat sterilized
glucocorticoid suspensions
glucocorticoid
suspensions
Prior art date
Application number
DK05851715.2T
Other languages
English (en)
Inventor
Paul Ronald
Adrian Ashley
Paul Lamb
Donald Macdonald
Martin Oliver
Matthew Pollard
John Miller
Original Assignee
Norton Healthcare Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Norton Healthcare Ltd filed Critical Norton Healthcare Ltd
Application granted granted Critical
Publication of DK1833462T3 publication Critical patent/DK1833462T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/02Nasal agents, e.g. decongestants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Otolaryngology (AREA)
  • Dispersion Chemistry (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Dermatology (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Apparatus For Disinfection Or Sterilisation (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK05851715.2T 2004-11-16 2005-11-16 Farmaceutisk fremstillingsfremgangsmåde til varmesteriliserede glucocorticoidsuspensioner DK1833462T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0425266A GB0425266D0 (en) 2004-11-16 2004-11-16 Pharmaceutical manufacturing process
PCT/US2005/041524 WO2006055632A2 (en) 2004-11-16 2005-11-16 Pharmaceutical manufacturing process for heat sterilized glucocorticoid suspensions

Publications (1)

Publication Number Publication Date
DK1833462T3 true DK1833462T3 (da) 2013-05-21

Family

ID=33523819

Family Applications (1)

Application Number Title Priority Date Filing Date
DK05851715.2T DK1833462T3 (da) 2004-11-16 2005-11-16 Farmaceutisk fremstillingsfremgangsmåde til varmesteriliserede glucocorticoidsuspensioner

Country Status (16)

Country Link
US (2) US8178519B2 (da)
EP (1) EP1833462B1 (da)
JP (1) JP5116478B2 (da)
KR (1) KR101226856B1 (da)
CN (2) CN102327211A (da)
AU (1) AU2005307825C1 (da)
CA (1) CA2587393C (da)
CY (1) CY1114150T1 (da)
DK (1) DK1833462T3 (da)
ES (1) ES2409713T3 (da)
GB (1) GB0425266D0 (da)
IL (2) IL183082A (da)
PL (1) PL1833462T3 (da)
PT (1) PT1833462E (da)
SI (1) SI1833462T1 (da)
WO (1) WO2006055632A2 (da)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PE20050941A1 (es) 2003-12-16 2005-11-08 Nycomed Gmbh Suspensiones acuosas de ciclesonida para nebulizacion
US10987361B2 (en) 2010-02-08 2021-04-27 Shenzhen Evergreen Therapeutics Co., Ltd. Treating auto-immune and auto-inflammatory diseases
WO2011097571A2 (en) 2010-02-08 2011-08-11 Prairie Pharmaceuticals, Llc Methods for the use of progestogen as a glucocorticoid sensitizer
US10993879B2 (en) * 2010-02-08 2021-05-04 Shenzhen Evergreen Therapeutics Co., Ltd. Pulmonary delivery of progestogen
US8888736B2 (en) 2010-04-30 2014-11-18 H R D Corporation High shear application in medical therapy
EP2563338A4 (en) * 2010-04-30 2014-06-18 H R D Corp HIGH SHEAR APPLICATION USED FOR DRUG DELIVERY
IN2014CH01890A (da) * 2014-04-10 2015-10-16 Aurobindo Pharma Ltd
JP6521351B2 (ja) * 2014-10-14 2019-05-29 テックプロジェクトサービス株式会社 ウィルス不活化およびサンプリング装置
KR20170075720A (ko) 2014-10-29 2017-07-03 알.피.쉐러 테크놀러지즈 엘엘씨 반전 블로우성형-충전-밀봉 패키징
CN104739811A (zh) * 2015-02-27 2015-07-01 上海臣邦医药科技有限公司 一种糖皮质激素雾化吸入混悬液及其制备方法
US20190269616A1 (en) * 2015-12-07 2019-09-05 Emcure Pharmaceuticals Limited Sterile parenteral suspensions
CN106904723A (zh) * 2017-02-24 2017-06-30 东华大学 利用过氧化钙氧化去除水中糖皮质激素的方法
WO2022098321A1 (en) * 2020-11-09 2022-05-12 Arven Ilac Sanayi Ve Ticaret Anonim Sirketi Process for the preparation of sterilised suspensions for the administration by inhalation
CN112891328A (zh) * 2021-04-12 2021-06-04 上海方予健康医药科技有限公司 一种吸入用布***混悬液的制备方法
WO2022231533A1 (en) * 2021-04-29 2022-11-03 Arven Ilac Sanayi Ve Ticaret Anonim Sirketi Process for the preparation of sterilized suspensions for the inhalation by nebulization

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3962430A (en) * 1974-08-07 1976-06-08 Merck & Co., Inc. Sterilization of solid non-electrolyte medicinal agents employing sodium chloride
DE4026978A1 (de) * 1990-08-25 1992-02-27 Bayer Ag Auf traegern angebrachte ein- oder mehrlagige schichtelemente und ihre herstellung
GB9410222D0 (en) * 1994-05-21 1994-07-06 Glaxo Wellcome Australia Ltd Medicaments
SE9704186D0 (sv) * 1997-11-14 1997-11-14 Astra Ab New composition of matter
US6066292A (en) * 1997-12-19 2000-05-23 Bayer Corporation Sterilization process for pharmaceutical suspensions
EP0938896A1 (en) 1998-01-15 1999-09-01 Novartis AG Autoclavable pharmaceutical compositions containing a chelating agent
IT1303692B1 (it) * 1998-11-03 2001-02-23 Chiesi Farma Spa Procedimento per la preparazione di sospensioni di particelle difarmaci da somministrare per inalazione.
JP4516165B2 (ja) * 1999-08-04 2010-08-04 株式会社ユポ・コーポレーション 多層樹脂延伸フィルム
EP1074369B1 (fr) * 1999-08-04 2005-10-05 Conception et Développement Michelin S.A. Procédé de fabrication de pièces en composite fortement sollicitées
WO2001028767A1 (fr) * 1999-10-21 2001-04-26 Nippon Steel Chemical Co., Ltd. Lamelle et procede de production
JP3862924B2 (ja) * 2000-03-27 2006-12-27 日東電工株式会社 光学フィルム積層体
WO2001072878A1 (en) * 2000-03-28 2001-10-04 The Board Of Regents For Oklahoma State University Assembly of free-standing films using a layer-by-layer process
JP4679795B2 (ja) * 2000-07-21 2011-04-27 株式会社セルシード 心筋様細胞シート、3次元構造体、心筋様組織及びそれらの製造法
DE60121023T2 (de) * 2000-11-24 2006-12-28 Breath Ltd., Biggin Hill Sterilisation von glucocorticosteriodsuspensionen
US20040022862A1 (en) 2000-12-22 2004-02-05 Kipp James E. Method for preparing small particles
US6541309B2 (en) * 2001-03-21 2003-04-01 Hewlett-Packard Development Company Lp Fabricating a molecular electronic device having a protective barrier layer
DE10145361A1 (de) * 2001-09-14 2003-04-03 Pari Gmbh Verfahren zur Herstellung von flüssigen, sterilen Zubereitungen zur Inhalation
ITMI20020808A1 (it) 2002-04-17 2003-10-17 Chiesi Farma Spa Procedimento per la preparazione di una sospensione sterile di particelle di beclometasone dipropionato da somministrare per inalazione
EP1454636A1 (en) 2003-03-04 2004-09-08 Dompé S.P.A. Sterilization of glucocorticoid drug particles for pulmonary delivery
GB0410995D0 (en) * 2004-05-17 2004-06-23 Norton Healthcare Ltd Heat sterilization of glucocorticosteroids

Also Published As

Publication number Publication date
PT1833462E (pt) 2013-05-22
JP5116478B2 (ja) 2013-01-09
US20120258939A1 (en) 2012-10-11
ES2409713T3 (es) 2013-06-27
SI1833462T1 (sl) 2013-07-31
IL183082A (en) 2014-09-30
GB0425266D0 (en) 2004-12-15
CN101068531A (zh) 2007-11-07
IL228730A0 (en) 2013-12-31
IL228730A (en) 2016-12-29
KR101226856B1 (ko) 2013-01-25
IL183082A0 (en) 2008-03-20
AU2005307825A1 (en) 2006-05-26
CN101068531B (zh) 2011-10-05
WO2006055632A2 (en) 2006-05-26
CA2587393C (en) 2010-09-28
CY1114150T1 (el) 2016-07-27
US20080269178A1 (en) 2008-10-30
PL1833462T3 (pl) 2013-10-31
AU2005307825C1 (en) 2012-08-09
EP1833462B1 (en) 2013-04-17
WO2006055632A3 (en) 2007-05-24
EP1833462A2 (en) 2007-09-19
KR20070089675A (ko) 2007-08-31
AU2005307825B2 (en) 2011-10-13
JP2008531467A (ja) 2008-08-14
CA2587393A1 (en) 2006-05-26
CN102327211A (zh) 2012-01-25
US8178519B2 (en) 2012-05-15

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