DK1778867T3 - Fremgangsmåder og sammensætninger til detektering af nucleinsyrer i en biologisk prøve - Google Patents
Fremgangsmåder og sammensætninger til detektering af nucleinsyrer i en biologisk prøveInfo
- Publication number
- DK1778867T3 DK1778867T3 DK05767727.0T DK05767727T DK1778867T3 DK 1778867 T3 DK1778867 T3 DK 1778867T3 DK 05767727 T DK05767727 T DK 05767727T DK 1778867 T3 DK1778867 T3 DK 1778867T3
- Authority
- DK
- Denmark
- Prior art keywords
- capture
- nucleic acid
- hairpin
- methods
- sample
- Prior art date
Links
- 150000007523 nucleic acids Chemical class 0.000 title abstract 5
- 108020004707 nucleic acids Proteins 0.000 title abstract 4
- 102000039446 nucleic acids Human genes 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 2
- 239000012472 biological sample Substances 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 239000000523 sample Substances 0.000 abstract 7
- 238000001514 detection method Methods 0.000 abstract 2
- 108091034117 Oligonucleotide Proteins 0.000 abstract 1
- 239000011541 reaction mixture Substances 0.000 abstract 1
- 230000009870 specific binding Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
- C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US58542104P | 2004-07-01 | 2004-07-01 | |
| PCT/US2005/023555 WO2006007567A2 (en) | 2004-07-01 | 2005-06-29 | Methods and compositions to detect nucleic acids in a biological sample |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1778867T3 true DK1778867T3 (da) | 2010-08-02 |
Family
ID=35457287
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK05767727.0T DK1778867T3 (da) | 2004-07-01 | 2005-06-29 | Fremgangsmåder og sammensætninger til detektering af nucleinsyrer i en biologisk prøve |
Country Status (9)
| Country | Link |
|---|---|
| US (3) | US8034554B2 (da) |
| EP (1) | EP1778867B1 (da) |
| JP (1) | JP5020818B2 (da) |
| AT (1) | ATE466107T1 (da) |
| AU (2) | AU2005262357B2 (da) |
| CA (1) | CA2572472C (da) |
| DE (1) | DE602005020943D1 (da) |
| DK (1) | DK1778867T3 (da) |
| WO (1) | WO2006007567A2 (da) |
Families Citing this family (97)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006007567A2 (en) | 2004-07-01 | 2006-01-19 | Gen-Probe Incorporated | Methods and compositions to detect nucleic acids in a biological sample |
| JP5020825B2 (ja) * | 2004-12-08 | 2012-09-05 | ジェン−プローブ・インコーポレーテッド | 複数型のヒトパピローマウイルスに由来する核酸の検出 |
| ES2381279T3 (es) * | 2005-05-06 | 2012-05-24 | Gen-Probe Incorporated | Métodos y productos para la captura de ácido nucleico diana |
| US8632970B2 (en) * | 2005-05-09 | 2014-01-21 | Affymetrix, Inc. | Multiplex capture of nucleic acids |
| EP1924591A4 (en) * | 2005-09-16 | 2009-04-15 | Primera Biosystems Inc | COMPOSITIONS AND METHODS FOR CLEANING NUCLEIC ACIDS |
| AU2006304721B2 (en) | 2005-10-17 | 2012-01-19 | Gen-Probe Incorporated | Compositions and methods to detect Legionella pneumophila nucleic acid |
| EP3561071B1 (en) * | 2006-02-13 | 2020-12-16 | Fluidigm Canada Inc. | Gene expression assays conducted by elemental analysis |
| ATE514794T1 (de) * | 2006-05-12 | 2011-07-15 | Gen Probe Inc | Zusammensetzungen und verfahren für den nachweis von enterokokken-nukleinsäuren |
| DK1945821T3 (da) | 2006-06-06 | 2011-03-07 | Gen Probe Inc | Mærkede oligonukleotider og anvendelse deraf i fremgangsmåder til amplifikation af nukleinsyrer |
| EP2407558A1 (en) * | 2006-10-31 | 2012-01-18 | Noxxon Pharma AG | Methods for the detection of a single- or double-stranded nucleic acid molecule |
| CN105925696A (zh) * | 2006-11-06 | 2016-09-07 | 科隆迪亚戈有限公司 | 使用结合元件用于分析的装置和方法 |
| AU2016202243B2 (en) * | 2006-11-06 | 2017-12-14 | Clondiag Gmbh | Assays |
| AU2014200826B2 (en) * | 2006-11-06 | 2016-01-14 | Clondiag Gmbh | Assays |
| EP3095873B1 (en) | 2006-12-21 | 2018-04-18 | Gen-Probe Incorporated | Methods and compositions for nucleic acid amplification |
| EP1978111B1 (en) | 2007-04-02 | 2013-03-27 | Gen-Probe Incorporated | Compositions, kits and related methods for the detection and/or monitoring of Pseudomonas aeruginosa |
| NZ582786A (en) * | 2007-07-23 | 2012-09-28 | Clondiag Gmbh | Assays for nucleic acids |
| US20090162845A1 (en) * | 2007-12-20 | 2009-06-25 | Elazar Rabbani | Affinity tag nucleic acid and protein compositions, and processes for using same |
| CA2715991A1 (en) * | 2007-12-26 | 2009-07-09 | Gen-Probe Incorporated | Amplification oligomers and methods to detect candida albicans 26s rrna or encoding dna |
| US20090215050A1 (en) * | 2008-02-22 | 2009-08-27 | Robert Delmar Jenison | Systems and methods for point-of-care amplification and detection of polynucleotides |
| US10316352B2 (en) * | 2008-05-13 | 2019-06-11 | Gen-Probe Incorporated | Methods of capturing a target nucleic acid for amplification and detection using an inactivatable target capture oligomer |
| US8703421B2 (en) | 2008-05-30 | 2014-04-22 | Gen-Probe Incorporated | Compositions, kits and related methods for the detection and/or monitoring of Salmonella |
| ES2532153T3 (es) * | 2008-07-18 | 2015-03-24 | Trovagene, Inc. | Métodos para la detección de secuencias de ácidos nucleicos "ultracortos" basados en PCR |
| EP2367958B1 (en) * | 2008-11-25 | 2017-08-23 | Gen-Probe Incorporated | Compositions and methods for detecting small rnas, and uses thereof |
| WO2010078374A1 (en) | 2008-12-30 | 2010-07-08 | Gen-Probe Incorporated | Compositions, kits and related methods for the detection and/or monitoring of listeria |
| CA2768768C (en) | 2009-06-23 | 2021-08-24 | Gen-Probe Incorporated | Compositions and methods for detecting nucleic acid from mollicutes |
| US9169512B2 (en) | 2009-07-01 | 2015-10-27 | Gen-Probe Incorporated | Methods and compositions for nucleic acid amplification |
| WO2013132700A1 (ja) * | 2012-03-05 | 2013-09-12 | 日本碍子株式会社 | 標的核酸の検出方法 |
| CA2770888C (en) | 2009-08-31 | 2020-04-14 | Gen-Probe Incorporated | Dengue virus assay |
| WO2011103274A1 (en) | 2010-02-17 | 2011-08-25 | Gen-Probe Incorporated | Compositions and methods to detect atopobium vaginae nucleic acid |
| CA3011697C (en) | 2010-04-21 | 2020-04-07 | Gen-Probe Incorporated | Compositions, methods and kits to detect herpes simplex virus nucleic acids |
| EP2611932A2 (en) | 2010-08-30 | 2013-07-10 | Gen-Probe Incorporated | Compositions, methods and reaction mixtures for the detection of xenotropic murine leukemia virus-related virus |
| EP2616555B1 (en) * | 2010-09-16 | 2017-11-08 | Gen-Probe Incorporated | Capture probes immobilizable via l-nucleotide tail |
| EP3438289A1 (en) | 2010-10-04 | 2019-02-06 | Gen-Probe Prodesse, Inc. | Compositions, methods and kits to detect adenovirus nucleic acids |
| AU2011323478B2 (en) | 2010-11-01 | 2015-09-10 | Gen-Probe Incorporated | Integrated capture and amplification of target nucleic acid for sequencing |
| EP2683833B1 (en) | 2011-03-10 | 2018-09-26 | Gen-Probe Incorporated | Methods for the selection and optimization of oligonucleotide tag sequences |
| AU2012249751B2 (en) | 2011-04-25 | 2016-11-03 | Gen-Probe Incorporated | Compositions and methods for detecting BV-associated bacterial nucleic acid |
| AU2012284307A1 (en) | 2011-07-15 | 2013-05-09 | Gen-Probe Incorporated | Compositions and method for detecting human parvovirus nucleic acid and for detecting hepatitis A virus nucleic acids in single-plex or multiplex assays |
| US10767208B2 (en) | 2011-09-06 | 2020-09-08 | Gen-Probe Incorporated | Closed nucleic acid structures |
| WO2013036928A1 (en) | 2011-09-08 | 2013-03-14 | Gen-Probe Incorporated | Compositions and methods for detecting bv-associated bacterial nucleic acid |
| EP2758547B1 (en) | 2011-09-21 | 2015-09-16 | Gen-Probe Incorporated | Methods for amplifying nucleic acid using tag-mediated displacement |
| US10152569B2 (en) | 2011-09-26 | 2018-12-11 | Gen-Probe Incorporated | Algorithms for sequence determinations |
| DE102011120550B4 (de) | 2011-12-05 | 2013-11-07 | Gen-Probe Prodesse, Inc. | Zusammensetzungen, Verfahren und Kits zur Detektion von Adenovirusnukleinsäuren |
| CN104169438B (zh) * | 2012-02-01 | 2019-02-26 | 简·探针公司 | 非对称发夹靶标捕获低聚物 |
| CA2865281C (en) | 2012-02-24 | 2021-11-23 | Gen-Probe Prodesse, Inc. | Detection of shiga toxin genes in bacteria |
| AU2013205110B2 (en) | 2012-04-24 | 2016-10-13 | Gen-Probe Incorporated | Compositions, Methods and Kits to Detect Herpes Simplex Virus Nucleic Acids |
| AU2013205064B2 (en) | 2012-06-04 | 2015-07-30 | Gen-Probe Incorporated | Compositions and Methods for Amplifying and Characterizing HCV Nucleic Acid |
| AU2013308647B2 (en) | 2012-08-30 | 2018-10-18 | Gen-Probe Incorporated | Multiphase nucleic acid amplification |
| AU2013205122B2 (en) | 2012-10-11 | 2016-11-10 | Gen-Probe Incorporated | Compositions and Methods for Detecting Human Papillomavirus Nucleic Acid |
| AU2013205090B2 (en) | 2012-12-07 | 2016-07-28 | Gen-Probe Incorporated | Compositions and Methods for Detecting Gastrointestinal Pathogen Nucleic Acid |
| EP2976435B1 (en) * | 2013-03-19 | 2017-10-25 | Directed Genomics, LLC | Enrichment of target sequences |
| JP6898736B2 (ja) | 2013-08-14 | 2021-07-07 | ジェン−プローブ・インコーポレーテッド | Ｈｅｖ核酸を検出するための組成物および方法 |
| EP3670664B1 (en) | 2014-02-28 | 2022-09-07 | Gen-Probe Incorporated | Method of isolating nucleic acid from specimens in liquid-based cytology preservatives containing formaldehyde |
| GB2528344B (en) | 2014-02-28 | 2018-10-31 | Gen Probe Inc | Method of isolating nucleic acid from specimens in liquid-based cytology preservatives containing formaldehyde |
| DE102015220401B4 (de) | 2014-10-20 | 2022-12-29 | Gen-Probe Incorporated | Erythrozyten-Lyselösung |
| US10865433B2 (en) | 2015-01-09 | 2020-12-15 | Gen-Probe Incorporated | Reaction mixtures for diagnosing bacterial vaginosis |
| US20160258938A1 (en) * | 2015-03-04 | 2016-09-08 | Headway Technologies, Inc. | Method of detecting an analyte in a sample |
| EP3910075A1 (en) | 2015-03-16 | 2021-11-17 | Gen-Probe Incorporated | Kits for detecting bacterial nucleic acid and diagnosing bacterial vaginosis |
| CA3010232A1 (en) | 2016-01-04 | 2017-07-13 | Gen-Probe Incorporated | Methods and compositions for detecting candida species |
| WO2017139672A1 (en) * | 2016-02-11 | 2017-08-17 | Htg Molecular Diagnostics, Inc. | Method of direct target sequencing using nuclease protection |
| JP6584986B2 (ja) * | 2016-03-18 | 2019-10-02 | 株式会社東芝 | 核酸検出方法 |
| CA3232826A1 (en) | 2016-04-27 | 2017-11-02 | Gen-Probe Incorporated | Blood cell lysis reagent |
| AU2017278065B2 (en) | 2016-06-10 | 2020-09-10 | Gen-Probe Incorporated | Compositions and methods for detecting Zika virus nucleic acid |
| EP3529381B1 (en) | 2016-10-19 | 2022-07-06 | Gen-Probe Incorporated | Compositions and methods for detecting or quantifying hepatitis c virus |
| WO2018094171A1 (en) | 2016-11-21 | 2018-05-24 | Gen-Probe Incorporated | Compositions and methods for detecting or quantifying hepatitis b virus |
| EP3601617B3 (en) | 2017-03-24 | 2024-03-20 | Gen-Probe Incorporated | Compositions and methods for detecting or quantifying parainfluenza virus |
| CA3225653A1 (en) | 2017-03-25 | 2018-10-04 | Gen-Probe Incorporated | Methods and compositions to detect rhinovirus nucleic acids |
| CN110612354A (zh) | 2017-05-11 | 2019-12-24 | 简·探针公司 | 用于分离靶核酸的组合物和方法 |
| JP7292217B2 (ja) | 2017-06-07 | 2023-06-16 | ジーイーエヌ－プローブ・インコーポレーテッド | 試料中のバベシア種の核酸の検出 |
| WO2018227182A2 (en) * | 2017-06-09 | 2018-12-13 | University Of Houston System | Force-modulated hybridization for visualizing nucleic acid length and function |
| US11859257B2 (en) | 2017-08-11 | 2024-01-02 | Gen-Probe Incorporated | Compositions and methods for detecting Staphylococcus aureus |
| EP3710595A1 (en) | 2017-11-17 | 2020-09-23 | Gen-Probe Incorporated | Compositions and methods for detecting c1orf43 nucleic acid |
| WO2019118550A1 (en) | 2017-12-13 | 2019-06-20 | Gen-Probe Incorporated | Methods for biological sample processing |
| JP2021506274A (ja) | 2017-12-15 | 2021-02-22 | ジェン−プローブ・インコーポレーテッド | 毒素産生Ｃｌｏｓｔｒｉｄｉｕｍ ｄｉｆｆｉｃｉｌｅを検出するための組成物および方法 |
| AU2019286648B2 (en) | 2018-06-13 | 2023-11-23 | Gen-Probe Incorporated | Compositions and methods for detecting group B Streptococcus nucleic acid |
| WO2020028631A1 (en) | 2018-08-01 | 2020-02-06 | Gen-Probe Incorporated | Compositions and methods for detecting nucleic acids of epstein-barr virus |
| AU2019326462A1 (en) | 2018-08-21 | 2021-03-25 | Gen-Probe Incorporated | Compositions and methods for amplifying, detecting or quantifying human cytomegalovirus |
| AU2019324196A1 (en) | 2018-08-24 | 2021-03-18 | Gen-Probe Incorporated | Compositions and methods for detecting bacterial nucleic acid and diagnosing bacterial vaginosis |
| CN109337956B (zh) * | 2018-09-07 | 2022-08-19 | 上海思路迪生物医学科技有限公司 | 基于ngs技术富集多基因茎环探针设计方法及试剂盒 |
| CN113195743A (zh) | 2018-10-22 | 2021-07-30 | 简·探针公司 | 扩增，检测或定量人类多瘤病毒bk病毒的组合物和方法 |
| TW202030333A (zh) | 2018-12-20 | 2020-08-16 | 美商簡 探針公司 | 用於檢測瘧原蟲物種核酸之組成物及方法 |
| EP3914732A1 (en) | 2019-01-25 | 2021-12-01 | Gen-Probe Incorporated | Detection of drug-resistant mycoplasma genitalium |
| US20220098647A1 (en) | 2019-03-22 | 2022-03-31 | Gen-Probe Incorporated | Compositions and Methods for Detecting Group A Streptococcus |
| KR102336454B1 (ko) * | 2019-06-17 | 2021-12-08 | 강릉원주대학교산학협력단 | 핵산 검출 방법 |
| AU2020299621A1 (en) | 2019-07-03 | 2022-02-24 | Gen-Probe Incorporated | Oligonucleotides for use in determining the presence of Trichomonas vaginalis in a sample. |
| AU2020384888A1 (en) | 2019-11-14 | 2022-06-23 | Gen-Probe Incorporated | Compositions and methods for capturing target nucleic acids |
| WO2021178644A1 (en) | 2020-03-04 | 2021-09-10 | Gen-Probe Incorporated | Compositions and methods for detecting sars-cov-2 nucleic acid |
| EP4146821A1 (en) | 2020-05-07 | 2023-03-15 | Grifols Diagnostic Solutions Inc. | Methods and compositions for detecting sars-cov-2 nucleic acid |
| WO2022197634A1 (en) | 2021-03-15 | 2022-09-22 | Gen-Probe Incorporated | Compositions and methods for biological sample processing |
| US20240218469A1 (en) | 2021-05-14 | 2024-07-04 | Gen-Probe Incorporated | Compositions and methods for detecting human adenovirus nucleic acid |
| WO2023278529A1 (en) | 2021-07-01 | 2023-01-05 | Gen-Probe Incorporated | Enzyme formulations and reaction mixtures for nucleic acid amplification |
| EP4382621A2 (en) | 2021-07-27 | 2024-06-12 | Gen-Probe Incorporated | Compositions and methods for detecting c. coli and at least one of salmonella, c. jejuni, shigella, and stec |
| CN114107446A (zh) * | 2021-12-16 | 2022-03-01 | 福建和瑞基因科技有限公司 | 一种核酸的检测试剂盒及其检测方法 |
| CN114250224B (zh) * | 2021-12-16 | 2024-02-27 | 福建和瑞基因科技有限公司 | 一种用于提取或检测样本中小分子rna的核酸组合物及其试剂盒和方法 |
| WO2024054924A1 (en) | 2022-09-08 | 2024-03-14 | Gen-Probe Incorporated | Method of detecting nucleic acid analytes using dual-specificity primers |
| WO2024081776A1 (en) | 2022-10-13 | 2024-04-18 | Gen-Probe Incorporated | Cellularity control for nucleic acid assays |
| WO2024081040A1 (en) * | 2022-10-15 | 2024-04-18 | Renato Rozental | Material and method for diagnosis of traumatic brain injury |
| WO2024137379A2 (en) | 2022-12-19 | 2024-06-27 | Gen-Probe Incorporated | Compositions and methods for detecting gastrointestinal pathogens |
Family Cites Families (70)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4174384A (en) * | 1975-06-30 | 1979-11-13 | Syva Company | Fluorescence quenching with immunological pairs in immunoassays |
| CA1190838A (en) | 1981-07-17 | 1985-07-23 | Cavit Akin | Homogeneous nucleic acid hybridization diagnostics by non-radiative energy transfer |
| FI63596C (fi) * | 1981-10-16 | 1983-07-11 | Orion Yhtymae Oy | Mikrobdiagnostiskt foerfarande som grundar sig pao skiktshybridisering av nukleinsyror och vid foerfarandet anvaenda kombinationer av reagenser |
| US4556643A (en) * | 1982-07-26 | 1985-12-03 | Agracetus | Assay method and probe for polynucleotide sequences |
| US6221581B1 (en) * | 1984-04-27 | 2001-04-24 | Enzo Diagnostics, Inc. | Processes for detecting polynucleotides, determining genetic mutations or defects in genetic material, separating or isolating nucleic acid of interest from samples, and useful compositions of matter and multihybrid complex compositions |
| CA1260372A (en) * | 1984-04-27 | 1989-09-26 | Elazar Rabbani | Hybridization method for the detection of genetic materials |
| US5288609A (en) * | 1984-04-27 | 1994-02-22 | Enzo Diagnostics, Inc. | Capture sandwich hybridization method and composition |
| US5268266A (en) * | 1984-05-07 | 1993-12-07 | Genetics Institute, Inc. | Process and nucleic acid construct for producing reagent complexes useful in determining target nucleotide sequences |
| US4766062A (en) * | 1984-05-07 | 1988-08-23 | Allied Corporation | Displacement polynucleotide assay method and polynucleotide complex reagent therefor |
| US4824776A (en) * | 1985-07-25 | 1989-04-25 | Molecular Biosystems, Inc. | Method for increasing the sensitivity of nucleic acid hybridization assays |
| US4725536A (en) * | 1985-09-19 | 1988-02-16 | Genetics Institute, Inc. | Reagent polynucleotide complex with multiple target binding regions, and kit and methods |
| US4752566A (en) * | 1985-12-17 | 1988-06-21 | Genetics Institute, Inc. | Displacement polynucleotide method and reagent complex employing labeled probe polynucleotide |
| US4818680A (en) * | 1985-12-18 | 1989-04-04 | Mary Collins | Method and kit involving displacement and rehybridization of labeled polynucleotide |
| CA1273552A (en) | 1985-12-23 | 1990-09-04 | Michael J. Heller | Fluorescent stokes shift probes for polynucleotide hybridization assays |
| US5714380A (en) * | 1986-10-23 | 1998-02-03 | Amoco Corporation | Closed vessel for isolating target molecules and for performing amplification |
| ZA877772B (en) * | 1986-10-23 | 1988-04-20 | Amoco Corporation | Target and background capture methods and apparatus for affinity assays |
| US5283174A (en) * | 1987-09-21 | 1994-02-01 | Gen-Probe, Incorporated | Homogenous protection assay |
| US5124246A (en) * | 1987-10-15 | 1992-06-23 | Chiron Corporation | Nucleic acid multimers and amplified nucleic acid hybridization assays using same |
| US5118801A (en) * | 1988-09-30 | 1992-06-02 | The Public Health Research Institute | Nucleic acid process containing improved molecular switch |
| EP0379369B1 (en) * | 1989-01-19 | 1996-09-04 | BEHRINGWERKE Aktiengesellschaft | Nucleic acid amplification using single primer |
| CA2049042A1 (en) * | 1989-03-10 | 1990-09-11 | Mark L. Collins | Preventing interference with affinity capture schemes |
| AU5269590A (en) * | 1989-03-10 | 1990-10-09 | Gene-Trak Systems | Immobilized oligonucleotide probes and uses therefor |
| US5589335A (en) * | 1989-04-05 | 1996-12-31 | Amoco Corporation | Hybridization promotion reagents |
| EP0405913B1 (en) * | 1989-06-30 | 1998-12-23 | Chiron Corporation | Hydrophobic nucleic acid probe |
| US5439793A (en) * | 1990-07-19 | 1995-08-08 | Syntex (U.S.A.) Inc. | Method for producing a polynucleotide having an intramolecularly base-paired structure |
| US5849481A (en) * | 1990-07-27 | 1998-12-15 | Chiron Corporation | Nucleic acid hybridization assays employing large comb-type branched polynucleotides |
| WO1992015708A1 (en) * | 1991-02-27 | 1992-09-17 | Amoco Corporation | Methods for improving the sensitivity of hybridization assays |
| US5445933A (en) * | 1992-09-15 | 1995-08-29 | Boehringer Mannheim Corporation | Strand displacement assay and complex useful therefor |
| EP0601889A2 (en) * | 1992-12-10 | 1994-06-15 | Maine Medical Center Research Institute | Nucleic acid probes |
| US6576419B1 (en) * | 1993-07-23 | 2003-06-10 | University Of Utah Research Foundation | Assay procedure using fluorogenic tracers |
| US5514546A (en) * | 1993-09-01 | 1996-05-07 | Research Corporation Technologies, Inc. | Stem-loop oligonucleotides containing parallel and antiparallel binding domains |
| US6156501A (en) * | 1993-10-26 | 2000-12-05 | Affymetrix, Inc. | Arrays of modified nucleic acid probes and methods of use |
| US6129828A (en) * | 1996-09-06 | 2000-10-10 | Nanogen, Inc. | Apparatus and methods for active biological sample preparation |
| US5925517A (en) * | 1993-11-12 | 1999-07-20 | The Public Health Research Institute Of The City Of New York, Inc. | Detectably labeled dual conformation oligonucleotide probes, assays and kits |
| US5538848A (en) * | 1994-11-16 | 1996-07-23 | Applied Biosystems Division, Perkin-Elmer Corp. | Method for detecting nucleic acid amplification using self-quenching fluorescence probe |
| US5681697A (en) * | 1993-12-08 | 1997-10-28 | Chiron Corporation | Solution phase nucleic acid sandwich assays having reduced background noise and kits therefor |
| US5861273A (en) | 1993-12-21 | 1999-01-19 | Celtrix Phamraceuticals, Inc. | Chromosomal expression of heterologous genes in bacterial cells |
| US5631148A (en) * | 1994-04-22 | 1997-05-20 | Chiron Corporation | Ribozymes with product ejection by strand displacement |
| AU2604995A (en) * | 1994-06-01 | 1995-12-21 | Hybridon, Inc. | Branched oligonucleotides as pathogen-inhibitory agents |
| US5731148A (en) * | 1995-06-07 | 1998-03-24 | Gen-Probe Incorporated | Adduct protection assay |
| US5770365A (en) * | 1995-08-25 | 1998-06-23 | Tm Technologies, Inc. | Nucleic acid capture moieties |
| WO1997023647A1 (en) | 1995-12-22 | 1997-07-03 | Behringwerke Aktiengesellschaft | Homogeneous amplification and detection of nucleic acids |
| DE69738687D1 (de) * | 1996-04-12 | 2008-06-26 | Phri Properties Inc | Sonden, kits und assays |
| US20030054376A1 (en) * | 1997-07-07 | 2003-03-20 | Mullis Kary Banks | Dual bead assays using cleavable spacers and/or ligation to improve specificity and sensitivity including related methods and apparatus |
| AU726821B2 (en) * | 1996-07-16 | 2000-11-23 | Gen-Probe Incorporated | Methods for detecting and amplifying nucleic acid sequences using modified oligonucleotides having increased target specific Tm |
| US5965363A (en) * | 1996-09-19 | 1999-10-12 | Genetrace Systems Inc. | Methods of preparing nucleic acids for mass spectrometric analysis |
| US6025133A (en) * | 1996-12-30 | 2000-02-15 | Gen-Probe Incorporated | Promoter-sequestered oligonucleoside and method of use |
| JP4222635B2 (ja) * | 1997-05-02 | 2009-02-12 | ジェン−プローブ・インコーポレーテッド | ２段階ハイブリダイゼーションおよびポリヌクレオチドの捕捉 |
| US6534273B2 (en) * | 1997-05-02 | 2003-03-18 | Gen-Probe Incorporated | Two-step hybridization and capture of a polynucleotide |
| WO1999022018A2 (en) * | 1997-10-27 | 1999-05-06 | Boston Probes, Inc. | Methods, kits and compositions pertaining to pna molecular beacons |
| AU762728B2 (en) * | 1998-07-02 | 2003-07-03 | Gen-Probe Incorporated | Molecular torches |
| US6399302B1 (en) * | 1998-08-21 | 2002-06-04 | University Of Virginia Patent Foundation | Signal generating oligonucleotide-based biosensor |
| DE69912443T2 (de) * | 1998-08-27 | 2004-08-19 | Bayer Corporation, Medfield | Oligomerreinigung durch selektion mittels zweier enden |
| AU776150B2 (en) * | 1999-01-28 | 2004-08-26 | Medical College Of Georgia Research Institute, Inc. | Composition and method for (in vivo) and (in vitro) attenuation of gene expression using double stranded RNA |
| CA2374421A1 (en) * | 1999-05-24 | 2000-11-30 | The Public Health Research Institute Of The City Of New York, Inc. | High specificity hairpin antisense oligonucleotides |
| US7052844B2 (en) * | 1999-12-21 | 2006-05-30 | Ingeneus, Inc. | Purification of DS-DNA using heteropolymeric capture probes and a triplex, quadruplex or homologous duplex binding mechanism |
| US7230092B2 (en) * | 2000-06-06 | 2007-06-12 | Luminex Molecular Diagnostics, Inc. | Capture moieties for nucleic acids and uses thereof |
| US6451588B1 (en) * | 2000-06-30 | 2002-09-17 | Pe Corporation (Ny) | Multipartite high-affinity nucleic acid probes |
| US6596490B2 (en) * | 2000-07-14 | 2003-07-22 | Applied Gene Technologies, Inc. | Nucleic acid hairpin probes and uses thereof |
| EP1366191A2 (en) * | 2000-12-11 | 2003-12-03 | Alexion Pharmaceuticals, Inc. | Nested oligonucleotides containing hairpin for nucleic acid amplification |
| USH2220H1 (en) | 2001-08-10 | 2008-07-01 | Snp Consortium | Identification and mapping of single nucleotide polymorphisms in the human genome |
| US7371580B2 (en) * | 2001-08-24 | 2008-05-13 | Agilent Technologies, Inc. | Use of unstructured nucleic acids in assaying nucleic acid molecules |
| US7345155B2 (en) * | 2001-11-02 | 2008-03-18 | Gen-Probe Incorporated | Probes, compositions and kits for determining the presence of Mycoplasma genitalium in a test sample |
| AU2003235894A1 (en) * | 2002-05-08 | 2003-12-12 | Arkray, Inc. | Method of detecting target nucleic acid |
| US7851150B2 (en) * | 2002-12-18 | 2010-12-14 | Third Wave Technologies, Inc. | Detection of small nucleic acids |
| US7741031B2 (en) * | 2003-03-07 | 2010-06-22 | The Public Health Research Institute Of The City Of New York | Optically decodable microcarries, arrays and methods |
| EP1635763B1 (en) * | 2003-06-09 | 2012-08-08 | Alnylam Pharmaceuticals Inc. | Method of treating neurodegenerative disease |
| US20050037362A1 (en) | 2003-08-11 | 2005-02-17 | Eppendorf Array Technologies, S.A. | Detection and quantification of siRNA on microarrays |
| WO2006007567A2 (en) | 2004-07-01 | 2006-01-19 | Gen-Probe Incorporated | Methods and compositions to detect nucleic acids in a biological sample |
| US20060292616A1 (en) * | 2005-06-23 | 2006-12-28 | U.S. Genomics, Inc. | Single molecule miRNA-based disease diagnostic methods |
-
2005
- 2005-06-29 WO PCT/US2005/023555 patent/WO2006007567A2/en active Application Filing
- 2005-06-29 AT AT05767727T patent/ATE466107T1/de not_active IP Right Cessation
- 2005-06-29 CA CA2572472A patent/CA2572472C/en active Active
- 2005-06-29 JP JP2007520409A patent/JP5020818B2/ja not_active Expired - Fee Related
- 2005-06-29 DK DK05767727.0T patent/DK1778867T3/da active
- 2005-06-29 US US11/173,915 patent/US8034554B2/en not_active Expired - Fee Related
- 2005-06-29 EP EP05767727A patent/EP1778867B1/en not_active Not-in-force
- 2005-06-29 DE DE602005020943T patent/DE602005020943D1/de active Active
- 2005-06-29 AU AU2005262357A patent/AU2005262357B2/en not_active Ceased
-
2009
- 2009-11-13 AU AU2009238261A patent/AU2009238261B2/en not_active Ceased
-
2010
- 2010-07-28 US US12/845,640 patent/US8551766B2/en active Active
-
2011
- 2011-04-14 US US13/087,282 patent/US8460869B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| JP5020818B2 (ja) | 2012-09-05 |
| AU2005262357B2 (en) | 2009-10-29 |
| AU2009238261A1 (en) | 2009-12-03 |
| EP1778867A2 (en) | 2007-05-02 |
| DE602005020943D1 (de) | 2010-06-10 |
| US20110250599A1 (en) | 2011-10-13 |
| CA2572472C (en) | 2013-08-13 |
| EP1778867B1 (en) | 2010-04-28 |
| ATE466107T1 (de) | 2010-05-15 |
| US8460869B2 (en) | 2013-06-11 |
| US20120231551A1 (en) | 2012-09-13 |
| WO2006007567A3 (en) | 2006-03-30 |
| US8551766B2 (en) | 2013-10-08 |
| AU2009238261B2 (en) | 2011-11-17 |
| AU2005262357A1 (en) | 2006-01-19 |
| WO2006007567A2 (en) | 2006-01-19 |
| JP2008504842A (ja) | 2008-02-21 |
| US8034554B2 (en) | 2011-10-11 |
| CA2572472A1 (en) | 2006-01-19 |
| US20060068417A1 (en) | 2006-03-30 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK1778867T3 (da) | Fremgangsmåder og sammensætninger til detektering af nucleinsyrer i en biologisk prøve | |
| WO2001092572A1 (fr) | Ensemble et procede de determination du type de hla | |
| IS8314A (is) | Ákvörðun fjölkirnisraðar | |
| EP2366803A3 (en) | Compositions and methods for detecting west nile virus | |
| DE60230672D1 (de) | Nukleinsäureanreicherung | |
| ATE188743T1 (de) | Oligonukleotiden komplementär zu mycobakterieller nukleinsäure | |
| WO2008028210A3 (de) | Bakteriennachweis | |
| WO2005019430A3 (en) | In vitro selection of aptamer beacons | |
| CA2525413A1 (en) | Compositions, methods and kits for determining the presence of trichomonas vaginalis in a test sample | |
| AU2023201805B2 (en) | Blood cell lysis reagent | |
| WO2005003386A3 (en) | Oligonucleotide ligation assay by detecting released pyrophosphate | |
| ATE485391T1 (de) | Zusammensetzungen, methoden und testssysteme zur bestimmung der präsenz von cryptosporidium organismen in einer testprobe | |
| CA2747479C (en) | Methods and reagents for shortening incubation times in hybridization assays | |
| WO2002101088A3 (en) | In vitro capture of nucleic acids via modified oligonucleotides and magnetic beads | |
| WO2004050911A3 (en) | Method for lowering both sequence variations and increase of base lines effects in diagnostic hybridisation assay, assay for performing such a method and probe for use in the assay | |
| CA2549059A1 (en) | Oligonucleotides for the detection of hepatitis b virus | |
| WO2006053779A3 (en) | Nucleic acid sequences that can be used as primers and probes in the amplification and detection of hsv dna and method for the amplification and detection of hsv dna using a transcription based amplification | |
| ATE463583T1 (de) | Verfahren zum nachweis von chlamydia trachomatis und kit dafür | |
| EP1323835A3 (en) | Method for determining biospecies contained in test specimen and kit used for the same | |
| ATE486138T1 (de) | Verfahren zum nachweis von bakterien der gattung mycobacterium (säureresistente bakterien) | |
| ATE307906T1 (de) | Verfahren zum nachweis von gram-positiven bakterien | |
| ATE312204T1 (de) | Methoden und zusammensetzungen zur detektion von spezies des mycobacterium avium-komplexes | |
| WO2005043114A3 (en) | Oligonucleotide probe sets and uses thereof | |
| JP2004187545A5 (da) | ||
| WO2004099443A3 (en) | Method for selection of optimal microarray probes |