DK174389A - Anvendelse af 3-substituerede 2-oxindol-1-carboxamid-forbindelser til fremstilling af farmaceutiske praeparater til inhibering af interleukin-1-biosyntese - Google Patents

Anvendelse af 3-substituerede 2-oxindol-1-carboxamid-forbindelser til fremstilling af farmaceutiske praeparater til inhibering af interleukin-1-biosyntese

Info

Publication number
DK174389A
DK174389A DK174389A DK174389A DK174389A DK 174389 A DK174389 A DK 174389A DK 174389 A DK174389 A DK 174389A DK 174389 A DK174389 A DK 174389A DK 174389 A DK174389 A DK 174389A
Authority
DK
Denmark
Prior art keywords
biosynthesis
substituted
interleukin
oxindol
preparation
Prior art date
Application number
DK174389A
Other languages
English (en)
Other versions
DK174389D0 (da
Inventor
Ivan George Otterness
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of DK174389D0 publication Critical patent/DK174389D0/da
Publication of DK174389A publication Critical patent/DK174389A/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Indole Compounds (AREA)
DK174389A 1988-04-13 1989-04-12 Anvendelse af 3-substituerede 2-oxindol-1-carboxamid-forbindelser til fremstilling af farmaceutiske praeparater til inhibering af interleukin-1-biosyntese DK174389A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/181,131 US4861794A (en) 1988-04-13 1988-04-13 3-substituted-2-oxindole-1-carboxamides as inhibitors of interleukin-1 biosynthesis

Publications (2)

Publication Number Publication Date
DK174389D0 DK174389D0 (da) 1989-04-12
DK174389A true DK174389A (da) 1989-10-16

Family

ID=22663029

Family Applications (1)

Application Number Title Priority Date Filing Date
DK174389A DK174389A (da) 1988-04-13 1989-04-12 Anvendelse af 3-substituerede 2-oxindol-1-carboxamid-forbindelser til fremstilling af farmaceutiske praeparater til inhibering af interleukin-1-biosyntese

Country Status (17)

Country Link
US (1) US4861794A (da)
EP (1) EP0337627B1 (da)
JP (1) JPH01305028A (da)
KR (1) KR920002327B1 (da)
AT (1) ATE89724T1 (da)
AU (1) AU601325B2 (da)
CA (1) CA1324761C (da)
DE (1) DE68906706T2 (da)
DK (1) DK174389A (da)
HU (1) HU203970B (da)
IE (1) IE63458B1 (da)
IL (1) IL89871A (da)
MY (1) MY103871A (da)
NZ (1) NZ228711A (da)
PH (1) PH25884A (da)
PT (1) PT90248B (da)
ZA (1) ZA892623B (da)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5300655A (en) * 1989-04-18 1994-04-05 Pfizer Inc. 2-carboxy-thiophene derivatives
US5047554A (en) 1989-04-18 1991-09-10 Pfizer Inc. 3-substituted-2-oxindole derivatives
IL95880A (en) * 1989-10-13 1995-12-31 Pfizer Use of 3-Transformed History of 2-Oxindole for the Preparation of Pharmaceuticals for Inhibition of Interlaukio-1 Biosynthesis
US5006547A (en) * 1990-03-19 1991-04-09 Pfizer Inc. Tenidap as an inhibitor of the release of elastase by neutrophils
US5008283A (en) * 1990-03-19 1991-04-16 Pfizer Inc. Use of tenidap to inhibit activation of collagenase and to inhibit the activity of myeloperoxidase
US5064851A (en) * 1990-07-24 1991-11-12 Pfizer Inc. 3-(1-substituted-pyrazoyl)-2-oxindole derivatives, compositions and use
DE69221794T2 (de) * 1991-01-21 1998-03-19 Shionogi Seiyaku Kk 3-benzyliden-1-carbamoyl-2-pyrrolidon-analoga
US5122534A (en) * 1991-02-08 1992-06-16 Pfizer Inc. Use of tenidap to reduce total serum cholesterol, ldl cholesterol and triglycerides
WO1992016226A1 (en) * 1991-03-19 1992-10-01 Smithkline Beecham Corporation Il-1 inhibitors
DE4111305C2 (de) * 1991-04-08 1994-12-01 Mack Chem Pharm Pharmazeutische Zubereitung zur rektalen Applikation, die ein 2-Oxindol-l-carboxamid-derivat enthält
US5298522A (en) * 1993-01-22 1994-03-29 Pfizer Inc. 6-chloro-5-fluoro-3-(2-thenoyl)-2-oxindole-1-carboxamide as an analgesic and anti-inflammatory agent while maintaining a normal urine protein/creatinine ratio
US5545656A (en) * 1995-04-05 1996-08-13 Pfizer Inc. 2-Oxidole-1-carboxamide pharmaceutical agents for the treatment of alzheimer's disease

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4556672A (en) * 1984-03-19 1985-12-03 Pfizer Inc. 3-Substituted 2-oxindole-1-carboxamides as analgesic and anti-inflammatory agents
US4569942A (en) * 1984-05-04 1986-02-11 Pfizer Inc. N,3-Disubstituted 2-oxindole-1-carboxamides as analgesic and antiinflammatory agents
US4678802A (en) * 1985-07-09 1987-07-07 Pfizer Inc. 1-acylcarbamoyloxindole-3-carboxamides as antiinflammatory agents
GB8517958D0 (en) * 1985-07-16 1985-08-21 Cellena Cell Eng Ag Compositions containing melatonin/homologues
JPH01501705A (ja) * 1986-01-30 1989-06-15 ユニバ−シテイ・オブ・ユタ 骨損失の治療
US4677132A (en) * 1986-03-12 1987-06-30 American Home Products Corporation Inhibition of bone resorption by etodolac
UA25898A1 (uk) * 1987-02-02 1999-02-26 Пфайзер Інк. Спосіб одержаhhя кристалічhої hатрієвої солі 5-хлор-3-(2-теhоїл)-2-оксііhдол-1-карбоксаміду

Also Published As

Publication number Publication date
HUT52377A (en) 1990-07-28
AU601325B2 (en) 1990-09-06
EP0337627B1 (en) 1993-05-26
ZA892623B (en) 1990-11-28
PT90248A (pt) 1989-11-10
DE68906706T2 (de) 1993-09-16
NZ228711A (en) 1997-02-24
PT90248B (pt) 1994-11-30
DK174389D0 (da) 1989-04-12
EP0337627A3 (en) 1991-01-02
IL89871A (en) 1994-11-11
CA1324761C (en) 1993-11-30
KR920002327B1 (ko) 1992-03-21
KR890015739A (ko) 1989-11-25
EP0337627A2 (en) 1989-10-18
IL89871A0 (en) 1989-12-15
ATE89724T1 (de) 1993-06-15
IE63458B1 (en) 1995-04-19
DE68906706D1 (de) 1993-07-01
MY103871A (en) 1993-09-30
IE891172L (en) 1989-10-13
HU203970B (en) 1991-11-28
PH25884A (en) 1991-12-02
JPH01305028A (ja) 1989-12-08
US4861794A (en) 1989-08-29
AU3271189A (en) 1989-10-19

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment