DK172587B1 - Fremgangsmåde til bestemmelse af koncentrationen af en analyt, analytisk anordning samt prøvesæt til brug ved fremgangsmåde - Google Patents

Fremgangsmåde til bestemmelse af koncentrationen af en analyt, analytisk anordning samt prøvesæt til brug ved fremgangsmåde Download PDF

Info

Publication number
DK172587B1
DK172587B1 DK198801830A DK183088A DK172587B1 DK 172587 B1 DK172587 B1 DK 172587B1 DK 198801830 A DK198801830 A DK 198801830A DK 183088 A DK183088 A DK 183088A DK 172587 B1 DK172587 B1 DK 172587B1
Authority
DK
Denmark
Prior art keywords
analyte
receptor
binding sites
labeled
marker
Prior art date
Application number
DK198801830A
Other languages
Danish (da)
English (en)
Other versions
DK183088D0 (da
DK183088A (da
Inventor
Roger Philip Ekins
Original Assignee
Multilyte Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26110703&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK172587(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GB868619206A external-priority patent/GB8619206D0/en
Application filed by Multilyte Ltd filed Critical Multilyte Ltd
Publication of DK183088D0 publication Critical patent/DK183088D0/da
Publication of DK183088A publication Critical patent/DK183088A/da
Application granted granted Critical
Publication of DK172587B1 publication Critical patent/DK172587B1/da

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54386—Analytical elements
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • G01N33/78—Thyroid gland hormones, e.g. T3, T4, TBH, TBG or their receptors
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/80—Fluorescent dyes, e.g. rhodamine
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/807—Apparatus included in process claim, e.g. physical support structures
    • Y10S436/808—Automated or kit

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Endocrinology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
  • Spectrometry And Color Measurement (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
DK198801830A 1986-08-06 1988-04-05 Fremgangsmåde til bestemmelse af koncentrationen af en analyt, analytisk anordning samt prøvesæt til brug ved fremgangsmåde DK172587B1 (da)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
GB868619206A GB8619206D0 (en) 1986-08-06 1986-08-06 Fluorometric determination of analyte concentration
GB8619206 1986-08-06
GB8700558 1987-08-06
EP87306995A EP0271974B1 (en) 1986-08-06 1987-08-06 Determination of analyte concentration using two labelling markers
EP87306995 1987-08-06
PCT/GB1987/000558 WO1988001058A1 (en) 1986-08-06 1987-08-06 Determination of analyte concentration using two labelling markers

Publications (3)

Publication Number Publication Date
DK183088D0 DK183088D0 (da) 1988-04-05
DK183088A DK183088A (da) 1988-04-05
DK172587B1 true DK172587B1 (da) 1999-02-08

Family

ID=26110703

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198801830A DK172587B1 (da) 1986-08-06 1988-04-05 Fremgangsmåde til bestemmelse af koncentrationen af en analyt, analytisk anordning samt prøvesæt til brug ved fremgangsmåde

Country Status (8)

Country Link
US (3) US5171695A (no)
JP (1) JP2690011B2 (no)
AT (1) ATE86385T1 (no)
AU (1) AU614935B2 (no)
DK (1) DK172587B1 (no)
FI (1) FI92881C (no)
NO (1) NO172517C (no)
WO (1) WO1988001058A1 (no)

Families Citing this family (54)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5599720A (en) * 1982-08-27 1997-02-04 Multilyte Limited Measurement of analyte concentration
US5807755A (en) * 1987-08-06 1998-09-15 Multilyte Limited Determination of ambient concentrations of several analytes
GB8803000D0 (en) * 1988-02-10 1988-03-09 Ekins Roger Philip Determination of ambient concentrations of several analytes
US5143854A (en) 1989-06-07 1992-09-01 Affymax Technologies N.V. Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
US6379895B1 (en) 1989-06-07 2002-04-30 Affymetrix, Inc. Photolithographic and other means for manufacturing arrays
US6551784B2 (en) 1989-06-07 2003-04-22 Affymetrix Inc Method of comparing nucleic acid sequences
US5800992A (en) 1989-06-07 1998-09-01 Fodor; Stephen P.A. Method of detecting nucleic acids
US5744101A (en) 1989-06-07 1998-04-28 Affymax Technologies N.V. Photolabile nucleoside protecting groups
CA2021658C (en) * 1989-08-25 2001-10-09 Myron J. Block Multiplex immunoassay system
US6008057A (en) * 1989-08-25 1999-12-28 Roche Diagnostics Corporation Immunoassay system
US5252743A (en) * 1989-11-13 1993-10-12 Affymax Technologies N.V. Spatially-addressable immobilization of anti-ligands on surfaces
WO1991013353A1 (en) * 1990-02-22 1991-09-05 The Royal Institution For The Advancement Of Learning (Mcgill University) A solid-phase interferometric immunoassay system
US5516635A (en) * 1991-10-15 1996-05-14 Ekins; Roger P. Binding assay employing labelled reagent
US6943034B1 (en) 1991-11-22 2005-09-13 Affymetrix, Inc. Combinatorial strategies for polymer synthesis
US5960344A (en) * 1993-12-20 1999-09-28 Norand Corporation Local area network having multiple channel wireless access
GB9326451D0 (en) * 1993-12-24 1994-02-23 Multilyte Ltd Binding assay
GB9326450D0 (en) * 1993-12-24 1994-02-23 Multilyte Ltd Binding assay
US7625697B2 (en) 1994-06-17 2009-12-01 The Board Of Trustees Of The Leland Stanford Junior University Methods for constructing subarrays and subarrays made thereby
US6017496A (en) 1995-06-07 2000-01-25 Irori Matrices with memories and uses thereof
US6331273B1 (en) 1995-04-25 2001-12-18 Discovery Partners International Remotely programmable matrices with memories
US6416714B1 (en) 1995-04-25 2002-07-09 Discovery Partners International, Inc. Remotely programmable matrices with memories
US6329139B1 (en) 1995-04-25 2001-12-11 Discovery Partners International Automated sorting system for matrices with memory
US5874214A (en) 1995-04-25 1999-02-23 Irori Remotely programmable matrices with memories
US5751629A (en) 1995-04-25 1998-05-12 Irori Remotely programmable matrices with memories
US6143247A (en) * 1996-12-20 2000-11-07 Gamera Bioscience Inc. Affinity binding-based system for detecting particulates in a fluid
US5679309A (en) * 1995-12-14 1997-10-21 Beckman Instruments, Inc. Automated random access analyzer
US6709869B2 (en) 1995-12-18 2004-03-23 Tecan Trading Ag Devices and methods for using centripetal acceleration to drive fluid movement in a microfluidics system
US5874216A (en) 1996-02-23 1999-02-23 Ensys Environmental Products, Inc. Indirect label assay device for detecting small molecules and method of use thereof
DE69733650T2 (de) * 1996-03-01 2006-04-20 Beckman Coulter, Inc., Fullerton System zum simultanen Durchführen einer Vielzahl von Ligandenbindungs-Untersuchungen
DE59607877D1 (de) * 1996-03-13 2001-11-15 Hoffmann La Roche Optochemisches Verfahren und Messanordnung zur Messung der Konzentration eines Analyten
US6143248A (en) * 1996-08-12 2000-11-07 Gamera Bioscience Corp. Capillary microvalve
US6632399B1 (en) * 1998-05-22 2003-10-14 Tecan Trading Ag Devices and methods for using centripetal acceleration to drive fluid movement in a microfluidics system for performing biological fluid assays
AU7591998A (en) 1997-05-23 1998-12-11 Gamera Bioscience Corporation Devices and methods for using centripetal acceleration to drive fluid movement in a microfluidics system
EP1004015B1 (en) 1997-08-15 2004-01-02 Alexion Pharmaceuticals, Inc. Apparatus for performing assays at reaction sites
US7157234B2 (en) 1997-10-24 2007-01-02 Beckman Coulter, Inc. Detection of very low quantities of analyte bound to a solid phase
GB9808836D0 (en) 1998-04-27 1998-06-24 Amersham Pharm Biotech Uk Ltd Microfabricated apparatus for cell based assays
GB9809943D0 (en) * 1998-05-08 1998-07-08 Amersham Pharm Biotech Ab Microfluidic device
JP2004529312A (ja) * 1999-06-18 2004-09-24 ガメラ バイオサイエンス コーポレイション 小型化均一アッセイ用のデバイスおよび方法
US6645733B1 (en) * 1999-06-25 2003-11-11 Ingeneus Corporation Fluorescent intensity method for assaying binding between proteins or peptides
US6267884B1 (en) * 2000-01-04 2001-07-31 Waters Investments Limited Capillary columns employing monodispersed particles
AU2001292959A1 (en) 2000-09-22 2002-04-02 Clontech Laboratories, Inc. Highly sensitive proteomic analysis methods and kits and systems for practicing the same
AU2002235170A1 (en) * 2000-11-07 2002-05-21 James O. Bowlby Jr. Method in quantitative analysis of gene and protein expression
JP3856214B2 (ja) * 2002-03-11 2006-12-13 横河電機株式会社 蛍光強度増強ビーズ
US20050079507A1 (en) * 2003-10-09 2005-04-14 Ye Fang Target evaluation using biological membrane arrays
GB0421838D0 (en) 2004-09-30 2004-11-03 Congenia S R L Cancer markers
US20060263265A1 (en) * 2005-05-23 2006-11-23 Der-Ren Kang Blood micro-separator
US20070111326A1 (en) * 2005-11-14 2007-05-17 Abbott Laboratories Diagnostic method for proteinaceous binding pairs, cardiovascular conditions and preeclampsia
CA2657576C (en) 2006-07-14 2023-10-31 The Regents Of The University Of California Cancer biomarkers and methods of use thereof
WO2011139721A1 (en) 2010-04-27 2011-11-10 The Regents Of The University Of California Cancer biomarkers and methods of use thereof
GB201016403D0 (en) 2010-09-29 2010-11-10 Bath Ventures Novel interaction between staphylococcus aureus Sbi and C3d protiens
EP3227687A4 (en) 2014-12-05 2018-10-24 Prelude, Inc. Dcis recurrence and invasive breast cancer
US11327072B2 (en) * 2017-02-09 2022-05-10 Promega Corporation Analyte detection immunoassay
US20220187301A1 (en) 2018-09-14 2022-06-16 Prelude Corporation Method of selection for treatment of subjects at risk of invasive breast cancer
GB2602268B (en) * 2020-12-18 2022-12-14 Forsite Diagnostics Ltd Time-resolved fluorescence reader and method

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4341957A (en) * 1975-11-26 1982-07-27 Analytical Radiation Corporation Fluorescent antibody composition for immunofluorometric assay
CA1111762A (en) * 1977-12-28 1981-11-03 David S. Frank Fluorescent rare earth chelate in polymeric latex particles
US4381291A (en) * 1979-02-23 1983-04-26 Ab Fortia Measurement of free ligands
DE2953610C1 (de) * 1979-03-19 1985-04-11 International Diagnostic Technology, Inc., Santa Clara, Calif. Verfahren zum Bestimmen eines immunologisch aktiven Stoffs
JPS5651665A (en) * 1979-09-24 1981-05-09 Radiochemical Centre Ltd Method of analysing isolated part of matter in biological fluid
US4366143A (en) * 1979-09-24 1982-12-28 Amersham International Public Limited Company Assay for the free portion of substances in biological fluids
DE3380777D1 (en) * 1982-08-27 1989-11-30 Roger Philip Ekins Measurement of analyte concentration

Also Published As

Publication number Publication date
FI890526A (fi) 1989-02-03
FI890526A0 (fi) 1989-02-03
FI92881B (fi) 1994-09-30
AU614935B2 (en) 1991-09-19
FI92881C (fi) 1995-01-10
JPH01503405A (ja) 1989-11-16
NO172517B (no) 1993-04-19
US5171695A (en) 1992-12-15
NO881241L (no) 1988-03-21
US20030082832A1 (en) 2003-05-01
US20020160524A1 (en) 2002-10-31
JP2690011B2 (ja) 1997-12-10
AU7755987A (en) 1988-02-24
NO881241D0 (no) 1988-03-21
DK183088D0 (da) 1988-04-05
WO1988001058A1 (en) 1988-02-11
ATE86385T1 (de) 1993-03-15
NO172517C (no) 1993-07-28
DK183088A (da) 1988-04-05

Similar Documents

Publication Publication Date Title
DK172587B1 (da) Fremgangsmåde til bestemmelse af koncentrationen af en analyt, analytisk anordning samt prøvesæt til brug ved fremgangsmåde
CA1113841A (en) Test device and method for its use
CN1759319B (zh) 生物液中肾上腺髓质素原中间区域部分肽在制备免疫诊断剂中的用途
FI92110C (fi) Useiden analyyttien vallitsevien konsentraatioiden määrittäminen
JP4619372B2 (ja) 改良された対照区画を有する免疫学的試験素子
DK156925B (da) Analytisk multilagsmateriale, dets fremstilling og anvendelse
EP0070300A1 (en) SOLID PHASE SYSTEM FOR TEST WITH BINDING AGENT.
DK172582B1 (da) Fremgangsmåde og testkit til bestemmelse af koncentrationen af en i en biologisk væske tilstedeværende aktiv forbindelse
JPH0750114B2 (ja) 免疫分析器具を用いる分析方法
US4786606A (en) Solid phase system for ligand assay
Gutierrez et al. Immunoassay methods based on fluorescence polarization
US20040161857A1 (en) Test strip for chromatography and process for producing the same
EP0271974B1 (en) Determination of analyte concentration using two labelling markers
US4032626A (en) Reagent and method for tbg assay
US4307071A (en) Analytical reagent and method
EP1716420A1 (en) Method for a rapid test
RU2480772C1 (ru) Способ одновременного детектирования тиротропина и общего тироксина в сухих пятнах крови
EP0596074A1 (en) Improved wash technique for immunoassay
Tsutsumi et al. A new radioimmunoassay of free thyroxine using 125I-labelled thyroxine—protein complex uninfluenced by albumin and thyroxine-binding globulin
JPH08297123A (ja) 蛋白質の免疫学的測定法とその方法の実施のためのキット
CN117554622A (zh) 一种微量白蛋白/肌酐联合检测试剂条及其制备方法和应用
Arakawa et al. Fluorescent enzyme immunoassay of free thyroxin using glucose oxidase as enzyme label
Keller et al. in [nsect tsio [ogy
JPH01257262A (ja) 均質なｔ−４取込み分析法
Simple et al. PROCEEDINGS OF CSCC CONVENTION

Legal Events

Date Code Title Description
PUP Patent expired