DK1713501T3 - Behandling af neurodegenerative sygdomme ved anvendelse af GPR49 - Google Patents
Behandling af neurodegenerative sygdomme ved anvendelse af GPR49Info
- Publication number
- DK1713501T3 DK1713501T3 DK04803345T DK04803345T DK1713501T3 DK 1713501 T3 DK1713501 T3 DK 1713501T3 DK 04803345 T DK04803345 T DK 04803345T DK 04803345 T DK04803345 T DK 04803345T DK 1713501 T3 DK1713501 T3 DK 1713501T3
- Authority
- DK
- Denmark
- Prior art keywords
- gpr49
- secretase
- interacting molecule
- treatment
- beta
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/80—Immunoglobulins specific features remaining in the (producing) cell, i.e. intracellular antibodies or intrabodies
- C07K2317/82—Immunoglobulins specific features remaining in the (producing) cell, i.e. intracellular antibodies or intrabodies functional in the cytoplasm, the inner aspect of the cell membrane, the nucleus or the mitochondria
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Genetics & Genomics (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pyridine Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP04001894 | 2004-01-29 | ||
EP04001895 | 2004-01-29 | ||
EP04007447 | 2004-03-26 | ||
EP2004004889 | 2004-05-07 | ||
EP2004004891 | 2004-05-07 | ||
PCT/EP2004/013539 WO2005074980A1 (en) | 2004-01-29 | 2004-11-29 | Treatment of neurodegenerative diseases by the use of gpr49 |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1713501T3 true DK1713501T3 (da) | 2008-05-26 |
Family
ID=38556372
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK04803345T DK1713501T3 (da) | 2004-01-29 | 2004-11-29 | Behandling af neurodegenerative sygdomme ved anvendelse af GPR49 |
Country Status (11)
Country | Link |
---|---|
US (1) | US20080025969A1 (da) |
EP (1) | EP1713501B1 (da) |
JP (1) | JP2007525491A (da) |
AT (1) | ATE383870T1 (da) |
AU (1) | AU2004315111B2 (da) |
CA (1) | CA2554353A1 (da) |
DE (1) | DE602004011400T2 (da) |
DK (1) | DK1713501T3 (da) |
ES (1) | ES2300852T3 (da) |
PT (1) | PT1713501E (da) |
WO (2) | WO2005074980A1 (da) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7521481B2 (en) | 2003-02-27 | 2009-04-21 | Mclaurin Joanne | Methods of preventing, treating and diagnosing disorders of protein aggregation |
AU2006335053A1 (en) * | 2005-11-21 | 2007-07-19 | Genentech, Inc. | Novel gene disruptions, compositions and methods relating thereto |
EP2022848A1 (en) | 2007-08-10 | 2009-02-11 | Hubrecht Institut | A method for identifying, expanding, and removing adult stem cells and cancer stem cells |
WO2010016766A2 (en) * | 2008-08-08 | 2010-02-11 | Koninklijke Nederlandse Akademie Van Wetenschappen | Antibodies recognizing endogenous human lgr5 and/or lgr6 |
US8362277B2 (en) | 2009-01-09 | 2013-01-29 | Board Of Regents Of The University Of Texas System | Pro-neurogenic compounds |
US9162980B2 (en) | 2009-01-09 | 2015-10-20 | Board Of Regents Of The University Of Texas System | Anti-depression compounds |
US9962368B2 (en) | 2009-01-09 | 2018-05-08 | Board Of Regents Of The University Of Texas System | Pro-neurogenic compounds |
AU2010203356B2 (en) | 2009-01-09 | 2015-11-26 | Board Of Regents Of The University Of Texas System | Pro-neurogenic compounds |
DK2590647T3 (da) * | 2010-07-07 | 2018-02-12 | Univ Texas | Pro-neurogene forbindelser |
AU2013305591B2 (en) | 2012-08-24 | 2017-04-13 | Board Of Regents Of The University Of Texas System | Pro-neurogenic compounds |
AU2013372386B2 (en) | 2013-01-10 | 2018-04-19 | Merck Patent Gmbh | Piperidinylcarbazole as antimalarial |
WO2015070234A2 (en) | 2013-11-11 | 2015-05-14 | Board Of Regents Of The University Of Texas System | Neuroprotective compounds and use thereof |
WO2015070237A1 (en) | 2013-11-11 | 2015-05-14 | Board Of Regents Of The University Of Texas System | Neuroprotective chemicals and methods for identifying and using same |
JP2017519795A (ja) | 2014-07-04 | 2017-07-20 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツングMerck Patent Gesellschaft mit beschraenkter Haftung | 抗寄生生物活性を有するアゼパニル(azepanyl)誘導体およびそれを含む医薬組成物 |
Family Cites Families (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8308235D0 (en) * | 1983-03-25 | 1983-05-05 | Celltech Ltd | Polypeptides |
US4816567A (en) * | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
US4980286A (en) * | 1985-07-05 | 1990-12-25 | Whitehead Institute For Biomedical Research | In vivo introduction and expression of foreign genetic material in epithelial cells |
US5225539A (en) * | 1986-03-27 | 1993-07-06 | Medical Research Council | Recombinant altered antibodies and methods of making altered antibodies |
US5223409A (en) * | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
US5530101A (en) * | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
US5096815A (en) * | 1989-01-06 | 1992-03-17 | Protein Engineering Corporation | Generation and selection of novel dna-binding proteins and polypeptides |
US5198346A (en) * | 1989-01-06 | 1993-03-30 | Protein Engineering Corp. | Generation and selection of novel DNA-binding proteins and polypeptides |
US5498538A (en) * | 1990-02-15 | 1996-03-12 | The University Of North Carolina At Chapel Hill | Totally synthetic affinity reagents |
US5633425A (en) * | 1990-08-29 | 1997-05-27 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
KR100272077B1 (ko) * | 1990-08-29 | 2000-11-15 | 젠팜인터내셔날,인코포레이티드 | 이종 항체를 생산할 수 있는 전이유전자를 가진 인간이외의 동물 |
US5625126A (en) * | 1990-08-29 | 1997-04-29 | Genpharm International, Inc. | Transgenic non-human animals for producing heterologous antibodies |
US5661016A (en) * | 1990-08-29 | 1997-08-26 | Genpharm International Inc. | Transgenic non-human animals capable of producing heterologous antibodies of various isotypes |
US5545806A (en) * | 1990-08-29 | 1996-08-13 | Genpharm International, Inc. | Ransgenic non-human animals for producing heterologous antibodies |
US5582981A (en) * | 1991-08-14 | 1996-12-10 | Gilead Sciences, Inc. | Method for identifying an oligonucleotide aptamer specific for a target |
AU4589297A (en) * | 1996-10-07 | 1998-05-05 | Scios Inc. | Method to identify direct inhibitors of the beta-amyloid forming enzyme gamma-secretase |
US6555339B1 (en) * | 1997-04-14 | 2003-04-29 | Arena Pharmaceuticals, Inc. | Non-endogenous, constitutively activated human protein-coupled receptors |
JP2002535289A (ja) * | 1999-01-22 | 2002-10-22 | ドウアリング,マシユー・ジヨン | 神経疾患のワクチン媒介治療 |
DE19941039A1 (de) * | 1999-08-28 | 2001-03-01 | Boehringer Ingelheim Pharma | gamma-Sekretase in vitro Testsystem |
GB0005894D0 (en) * | 2000-03-10 | 2000-05-03 | Glaxo Group Ltd | Assay |
WO2002061087A2 (en) * | 2000-12-19 | 2002-08-08 | Lifespan Biosciences, Inc. | Antigenic peptides, such as for g protein-coupled receptors (gpcrs), antibodies thereto, and systems for identifying such antigenic peptides |
EP1354950A4 (en) * | 2000-12-28 | 2005-01-12 | Asahi Kasei Pharma Corp | ACTIVATION GENE OF NF-KB |
AU2002228316A1 (en) * | 2001-01-29 | 2002-08-12 | Insight Strategy And Marketing Ltd | Carbazole derivatives and their uses as heparanase inhibitors |
AU2003245987A1 (en) * | 2002-06-26 | 2004-02-02 | Cellzome Ag | Components of the presenilin-complex |
EP1380644A1 (en) * | 2002-07-08 | 2004-01-14 | Kylix B.V. | The use of specified TCF target genes to identify drugs for the treatment of cancer, in particular colorectal cancer, in which TCF/beta-catenin/WNT signalling plays a central role |
US7056685B1 (en) * | 2002-11-05 | 2006-06-06 | Amgen Inc. | Receptor ligands and methods of modulating receptors |
US7189539B2 (en) * | 2003-11-25 | 2007-03-13 | Bristol-Myers Squibb Company | Polynucleotide encoding a human relaxin receptor, HGPRBMY5v1 |
-
2004
- 2004-11-29 DE DE602004011400T patent/DE602004011400T2/de active Active
- 2004-11-29 DK DK04803345T patent/DK1713501T3/da active
- 2004-11-29 PT PT04803345T patent/PT1713501E/pt unknown
- 2004-11-29 ES ES04803345T patent/ES2300852T3/es active Active
- 2004-11-29 JP JP2006549895A patent/JP2007525491A/ja not_active Withdrawn
- 2004-11-29 EP EP04803345A patent/EP1713501B1/en not_active Not-in-force
- 2004-11-29 WO PCT/EP2004/013539 patent/WO2005074980A1/en active IP Right Grant
- 2004-11-29 US US10/587,159 patent/US20080025969A1/en not_active Abandoned
- 2004-11-29 AT AT04803345T patent/ATE383870T1/de not_active IP Right Cessation
- 2004-11-29 AU AU2004315111A patent/AU2004315111B2/en not_active Expired - Fee Related
- 2004-11-29 CA CA002554353A patent/CA2554353A1/en not_active Abandoned
- 2004-12-01 WO PCT/EP2004/013620 patent/WO2005074971A1/en active Application Filing
Also Published As
Publication number | Publication date |
---|---|
DE602004011400T2 (de) | 2009-01-22 |
PT1713501E (pt) | 2008-04-30 |
AU2004315111B2 (en) | 2010-03-04 |
AU2004315111A1 (en) | 2005-08-18 |
WO2005074980A1 (en) | 2005-08-18 |
DE602004011400D1 (de) | 2008-03-06 |
ATE383870T1 (de) | 2008-02-15 |
CA2554353A1 (en) | 2005-08-18 |
EP1713501A1 (en) | 2006-10-25 |
ES2300852T3 (es) | 2008-06-16 |
WO2005074971A1 (en) | 2005-08-18 |
JP2007525491A (ja) | 2007-09-06 |
EP1713501B1 (en) | 2008-01-16 |
US20080025969A1 (en) | 2008-01-31 |
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