DK1696923T3 - Nikotinafgivelsesprodukt og fremgangsmåde til fremstilling deraf - Google Patents
Nikotinafgivelsesprodukt og fremgangsmåde til fremstilling derafInfo
- Publication number
- DK1696923T3 DK1696923T3 DK04801165T DK04801165T DK1696923T3 DK 1696923 T3 DK1696923 T3 DK 1696923T3 DK 04801165 T DK04801165 T DK 04801165T DK 04801165 T DK04801165 T DK 04801165T DK 1696923 T3 DK1696923 T3 DK 1696923T3
- Authority
- DK
- Denmark
- Prior art keywords
- nicotine
- delivery product
- preparation
- exchange resin
- cation exchange
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
- A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
- A24B15/10—Chemical features of tobacco products or tobacco substitutes
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
- A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
- A24B15/18—Treatment of tobacco products or tobacco substitutes
- A24B15/28—Treatment of tobacco products or tobacco substitutes by chemical substances
- A24B15/287—Treatment of tobacco products or tobacco substitutes by chemical substances by inorganic substances only
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/465—Nicotine; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/58—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
- A61K47/585—Ion exchange resins, e.g. polystyrene sulfonic acid resin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
- A61K9/0058—Chewing gums
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Zoology (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Addiction (AREA)
- Toxicology (AREA)
- Inorganic Chemistry (AREA)
- Psychiatry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DKPA200301782 | 2003-12-02 | ||
US50906303P | 2003-12-05 | 2003-12-05 | |
PCT/DK2004/000841 WO2005053691A2 (en) | 2003-12-02 | 2004-12-02 | Nicotine delivery product and method for producing it |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1696923T3 true DK1696923T3 (da) | 2009-12-21 |
Family
ID=34973436
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK04801165T DK1696923T3 (da) | 2003-12-02 | 2004-12-02 | Nikotinafgivelsesprodukt og fremgangsmåde til fremstilling deraf |
Country Status (6)
Country | Link |
---|---|
US (2) | US8741935B2 (de) |
EP (1) | EP1696923B1 (de) |
AT (1) | ATE439839T1 (de) |
DE (1) | DE602004022708D1 (de) |
DK (1) | DK1696923T3 (de) |
WO (1) | WO2005053691A2 (de) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SI1578422T1 (sl) | 2002-12-20 | 2007-12-31 | Niconovum Ab | Fizikalno in kemiäśno stabilni nikotin in mikrokristal na celulozo vsebujoäś material iz trdnih delcev |
WO2006128468A1 (en) * | 2005-06-01 | 2006-12-07 | Fertin Pharma A/S | A method of manufacturing a nicotine delivery product |
AU2007224586A1 (en) * | 2006-03-16 | 2007-09-20 | Niconovum Ab | Stable lozenge compositions providing rapid release of nicotine |
AU2007224584A1 (en) | 2006-03-16 | 2007-09-20 | Niconovum Ab | Improved snuff composition |
PT2198865E (pt) | 2008-12-19 | 2012-02-07 | Siegfried Ltd | Produto que contém nicotina |
US20110268809A1 (en) | 2010-04-28 | 2011-11-03 | Paul Andrew Brinkley | Nicotine-Containing Pharmaceutical Compositions |
US20110274628A1 (en) | 2010-05-07 | 2011-11-10 | Borschke August J | Nicotine-containing pharmaceutical compositions |
ES2610152T3 (es) | 2010-05-31 | 2017-04-26 | Fertin Pharma A/S | Formulación que comprende nicotina y una resina de intercambio catiónico |
US8728443B2 (en) | 2010-05-31 | 2014-05-20 | Fertin Pharma A/S | Formulation comprising nicotine and a cation exchange resin |
US9474303B2 (en) | 2011-09-22 | 2016-10-25 | R.J. Reynolds Tobacco Company | Translucent smokeless tobacco product |
US9629392B2 (en) | 2011-09-22 | 2017-04-25 | R.J. Reynolds Tobacco Company | Translucent smokeless tobacco product |
US9084439B2 (en) | 2011-09-22 | 2015-07-21 | R.J. Reynolds Tobacco Company | Translucent smokeless tobacco product |
US20130078307A1 (en) | 2011-09-22 | 2013-03-28 | Niconovum Usa, Inc. | Nicotine-containing pharmaceutical composition |
US9907748B2 (en) | 2011-10-21 | 2018-03-06 | Niconovum Usa, Inc. | Excipients for nicotine-containing therapeutic compositions |
US9763928B2 (en) | 2012-02-10 | 2017-09-19 | Niconovum Usa, Inc. | Multi-layer nicotine-containing pharmaceutical composition |
US20140255452A1 (en) | 2013-03-11 | 2014-09-11 | Niconovum Usa, Inc. | Method and apparatus for differentiating oral pouch products |
ITBO20130706A1 (it) * | 2013-12-20 | 2015-06-21 | Sino Business Ltd | Composizione per sigarette elettroniche |
US20170165252A1 (en) | 2015-12-10 | 2017-06-15 | Niconovum Usa Inc. | Protein-enriched therapeutic composition |
WO2017182084A1 (en) | 2016-04-21 | 2017-10-26 | Fertin Pharma A/S | Nicotine delivery product, related uses and oral dosage forms, and methods of production |
US20180103681A1 (en) * | 2016-10-18 | 2018-04-19 | Altria Client Services Llc | Methods and systems for increasing stability of the pre-vapor formulation of an e-vaping device |
CN112384504A (zh) | 2018-06-15 | 2021-02-19 | R.J.雷诺兹烟草公司 | 烟碱的纯化 |
US20210106516A1 (en) * | 2019-10-11 | 2021-04-15 | Fertin Pharma A/S | Ion-Exchange Composition With Water-Soluble Mucoadhesive Polymers |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3901248A (en) * | 1970-07-22 | 1975-08-26 | Leo Ab | Chewable smoking substitute composition |
US3845217A (en) * | 1972-11-16 | 1974-10-29 | Helsingborg L Ab | Buffered smoking substitute compositions |
US4692462A (en) | 1985-03-18 | 1987-09-08 | Menley & James Laboratories, Ltd. | Compositions and method of controlling transdermal penetration of topical and systemic agents |
ZA937452B (en) | 1992-10-15 | 1994-06-07 | Alza Corp | Delayed onset transdermal delivery device |
GB9310412D0 (en) | 1993-05-20 | 1993-07-07 | Danbiosyst Uk | Nasal nicotine system |
US6607752B2 (en) * | 2000-07-27 | 2003-08-19 | Rohm And Haas Company | Method for the anhydrous loading of nicotine onto ion exchange resins |
CN1615156B (zh) | 2002-01-18 | 2012-05-30 | 罗门哈斯公司 | 制备树脂酸酯的方法 |
US6586449B1 (en) * | 2002-05-28 | 2003-07-01 | Cambrex Charles City, Inc. | Nicotine-containing, controlled release composition and method |
-
2004
- 2004-12-02 EP EP04801165A patent/EP1696923B1/de active Active
- 2004-12-02 AT AT04801165T patent/ATE439839T1/de not_active IP Right Cessation
- 2004-12-02 WO PCT/DK2004/000841 patent/WO2005053691A2/en active Application Filing
- 2004-12-02 DE DE602004022708T patent/DE602004022708D1/de not_active Expired - Fee Related
- 2004-12-02 DK DK04801165T patent/DK1696923T3/da active
- 2004-12-02 US US10/581,628 patent/US8741935B2/en active Active
-
2014
- 2014-04-24 US US14/260,932 patent/US9801408B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
EP1696923A2 (de) | 2006-09-06 |
US20140230833A1 (en) | 2014-08-21 |
DE602004022708D1 (de) | 2009-10-01 |
EP1696923B1 (de) | 2009-08-19 |
ATE439839T1 (de) | 2009-09-15 |
WO2005053691A3 (en) | 2005-07-14 |
US9801408B2 (en) | 2017-10-31 |
WO2005053691A2 (en) | 2005-06-16 |
US20080038209A1 (en) | 2008-02-14 |
US8741935B2 (en) | 2014-06-03 |
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