DK1680405T3 - Bengamide derivatives and their use in the treatment of cancer diseases - Google Patents

Bengamide derivatives and their use in the treatment of cancer diseases

Info

Publication number
DK1680405T3
DK1680405T3 DK04765884T DK04765884T DK1680405T3 DK 1680405 T3 DK1680405 T3 DK 1680405T3 DK 04765884 T DK04765884 T DK 04765884T DK 04765884 T DK04765884 T DK 04765884T DK 1680405 T3 DK1680405 T3 DK 1680405T3
Authority
DK
Denmark
Prior art keywords
treatment
cancer diseases
bengamide derivatives
bengamide
derivatives
Prior art date
Application number
DK04765884T
Other languages
Danish (da)
Inventor
Holger Hoffmann
Sabine Haag-Richter
Michael Kurz
Heiko Tietgen
Original Assignee
Sanofi Aventis Deutschland
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis Deutschland filed Critical Sanofi Aventis Deutschland
Application granted granted Critical
Publication of DK1680405T3 publication Critical patent/DK1680405T3/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D223/00Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/02Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D223/06Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D223/08Oxygen atoms
    • C07D223/10Oxygen atoms attached in position 2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D223/00Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/02Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D223/06Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D223/12Nitrogen atoms not forming part of a nitro radical
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • C12N1/205Bacterial isolates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/10Nitrogen as only ring hetero atom
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DK04765884T 2003-10-24 2004-10-08 Bengamide derivatives and their use in the treatment of cancer diseases DK1680405T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10349669A DE10349669B3 (en) 2003-10-24 2003-10-24 Bengamide derivatives, process for their preparation and their use
PCT/EP2004/011244 WO2005044803A1 (en) 2003-10-24 2004-10-08 Bengamide derivatives, method for the production thereof and use thereof for the treatment of cancer

Publications (1)

Publication Number Publication Date
DK1680405T3 true DK1680405T3 (en) 2009-05-04

Family

ID=34484998

Family Applications (1)

Application Number Title Priority Date Filing Date
DK04765884T DK1680405T3 (en) 2003-10-24 2004-10-08 Bengamide derivatives and their use in the treatment of cancer diseases

Country Status (30)

Country Link
EP (2) EP1873146B1 (en)
JP (1) JP4769190B2 (en)
KR (1) KR20060120044A (en)
CN (2) CN101294173A (en)
AR (1) AR046553A1 (en)
AT (2) ATE420074T1 (en)
AU (1) AU2004287561B2 (en)
BR (1) BRPI0415529A (en)
CA (1) CA2543003A1 (en)
CL (1) CL2009000674A1 (en)
CY (1) CY1110458T1 (en)
DE (3) DE10349669B3 (en)
DK (1) DK1680405T3 (en)
ES (1) ES2320894T3 (en)
HK (1) HK1098131A1 (en)
HR (1) HRP20090187T1 (en)
IL (1) IL174524A (en)
MA (1) MA28213A1 (en)
ME (1) MEP33108A (en)
MX (1) MXPA06004084A (en)
NO (1) NO20062149L (en)
NZ (1) NZ546744A (en)
PL (1) PL1680405T3 (en)
PT (1) PT1680405E (en)
RS (1) RS20060263A (en)
RU (1) RU2357956C2 (en)
SI (1) SI1680405T1 (en)
UY (1) UY28574A1 (en)
WO (1) WO2005044803A1 (en)
ZA (1) ZA200602231B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2878525B1 (en) 2004-11-29 2007-02-23 Aventis Pharma Sa BENGAMIDES HAVING SUBSTITUTED CAPROLACTAM CYCLE, PREPARATION METHOD, COMPOSITIONS CONTAINING SAME AND USE THEREOF
FR2878528B1 (en) 2004-11-29 2008-05-16 Aventis Pharma Sa 2-ALCOXY-3,4,5-TRIHYDROXY-ALKYLAMIDES, PREPARATION THEREOF, COMPOSITIONS CONTAINING SAME AND USE THEREOF
FR2901555A1 (en) 2006-05-24 2007-11-30 Sanofi Aventis Sa 2-ALCOXY-3,4,5-TRIHYDROXY-ALKYLAMIDE-BENZOTHIAZEPINE, THEIR PREPARATION, COMPOSITIONS CONTAINING SAME AND USE THEREOF
FR2901556A1 (en) 2006-05-24 2007-11-30 Sanofi Aventis Sa 2-ALCOXY-3,4,5-TRIHYDROXY-ALKYLAMIDE DERIVATIVES, THEIR PREPARATION, COMPOSITIONS CONTAINING SAME AND USE THEREOF
FR2901554B1 (en) 2006-05-24 2011-04-01 Sanofi Aventis 2-ALCOXY-3,4,5-TRIHYDROXY-ALKYLAMIDE-BENZAZEPINE, PREPARATION THEREOF, COMPOSITIONS CONTAINING SAME AND USE THEREOF

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CO5140099A1 (en) * 1998-11-17 2002-03-22 Novartis Ag CERTAIN SUBSTITUTED CAPROLACTAMAS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND ITS USE IN TUMORS TREATMENT
JP2003532711A (en) * 2000-05-11 2003-11-05 ノバルティス アクチエンゲゼルシャフト Substituted caprolactam carbonates and caprolactam ethers and their use as antitumor agents
JP2004262793A (en) * 2003-02-28 2004-09-24 Noyaku Bio Technology Kaihatsu Gijutsu Kenkyu Kumiai Compound n-9011, its production method and use
CN1856486A (en) * 2003-07-25 2006-11-01 诺瓦提斯公司 Substituted lactams and their use as anti-cancer agents

Also Published As

Publication number Publication date
IL174524A0 (en) 2006-08-01
CN100398520C (en) 2008-07-02
ATE420074T1 (en) 2009-01-15
CN1871217A (en) 2006-11-29
AR046553A1 (en) 2005-12-14
HRP20090187T1 (en) 2009-05-31
MA28213A1 (en) 2006-10-02
PL1680405T3 (en) 2009-06-30
EP1680405A1 (en) 2006-07-19
NZ546744A (en) 2009-03-31
HK1098131A1 (en) 2007-07-13
PT1680405E (en) 2009-03-31
IL174524A (en) 2012-08-30
AU2004287561A1 (en) 2005-05-19
JP2007509084A (en) 2007-04-12
JP4769190B2 (en) 2011-09-07
DE502004008837D1 (en) 2009-02-26
CN101294173A (en) 2008-10-29
MEP33108A (en) 2010-10-10
RU2006117769A (en) 2007-11-27
WO2005044803A1 (en) 2005-05-19
UY28574A1 (en) 2005-05-31
CA2543003A1 (en) 2005-05-19
BRPI0415529A (en) 2006-12-26
NO20062149L (en) 2006-07-11
RU2357956C2 (en) 2009-06-10
ATE477244T1 (en) 2010-08-15
DE502004011536D1 (en) 2010-09-23
MXPA06004084A (en) 2006-06-27
SI1680405T1 (en) 2009-06-30
EP1873146A3 (en) 2008-05-21
DE10349669B3 (en) 2005-05-25
EP1680405B1 (en) 2009-01-07
EP1873146A2 (en) 2008-01-02
CY1110458T1 (en) 2015-04-29
ES2320894T3 (en) 2009-05-29
ZA200602231B (en) 2007-06-27
CL2009000674A1 (en) 2009-08-07
RS20060263A (en) 2008-09-29
EP1873146B1 (en) 2010-08-11
AU2004287561B2 (en) 2011-06-02
KR20060120044A (en) 2006-11-24

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