DK1666477T3 - 7-(4-trisubstitueret 3-cyclopropylaminomethyl-1- pyrrolidinyl)-quinoloncarboxylsyre-derivat - Google Patents

7-(4-trisubstitueret 3-cyclopropylaminomethyl-1- pyrrolidinyl)-quinoloncarboxylsyre-derivat

Info

Publication number
DK1666477T3
DK1666477T3 DK04787732.9T DK04787732T DK1666477T3 DK 1666477 T3 DK1666477 T3 DK 1666477T3 DK 04787732 T DK04787732 T DK 04787732T DK 1666477 T3 DK1666477 T3 DK 1666477T3
Authority
DK
Denmark
Prior art keywords
cyclopropylaminomethyl
trisubstituted
pyrrolidinyl
acid derivate
quinoloncarboxylic
Prior art date
Application number
DK04787732.9T
Other languages
English (en)
Inventor
Yoshikazu Asahina
Masaya Takei
Original Assignee
Kyorin Seiyaku Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyorin Seiyaku Kk filed Critical Kyorin Seiyaku Kk
Application granted granted Critical
Publication of DK1666477T3 publication Critical patent/DK1666477T3/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK04787732.9T 2003-09-10 2004-09-08 7-(4-trisubstitueret 3-cyclopropylaminomethyl-1- pyrrolidinyl)-quinoloncarboxylsyre-derivat DK1666477T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2003318897 2003-09-10
PCT/JP2004/013049 WO2005026147A1 (ja) 2003-09-10 2004-09-08 ７−（４−置換−３−シクロプロピルアミノメチル−１−ピロリジニル）キノロンカルボン酸誘導体

Publications (1)

Publication Number Publication Date
DK1666477T3 true DK1666477T3 (da) 2013-07-29

Family

ID=34308537

Family Applications (1)

Application Number Title Priority Date Filing Date
DK04787732.9T DK1666477T3 (da) 2003-09-10 2004-09-08 7-(4-trisubstitueret 3-cyclopropylaminomethyl-1- pyrrolidinyl)-quinoloncarboxylsyre-derivat

Country Status (18)

Country Link
US (2) US7514451B2 (da)
EP (1) EP1666477B1 (da)
JP (1) JP4639149B2 (da)
KR (1) KR101077755B1 (da)
CN (1) CN100410249C (da)
AU (1) AU2004272414B2 (da)
BR (1) BRPI0413964B8 (da)
CA (1) CA2536429C (da)
CY (1) CY1114476T1 (da)
DK (1) DK1666477T3 (da)
ES (1) ES2424676T3 (da)
NO (1) NO333481B1 (da)
NZ (1) NZ545472A (da)
PL (1) PL1666477T3 (da)
PT (1) PT1666477E (da)
SG (1) SG144936A1 (da)
SI (1) SI1666477T1 (da)
WO (1) WO2005026147A1 (da)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1666477E (pt) * 2003-09-10 2013-08-28 Kyorin Seiyaku Kk Derivado de 7-(4-substituído-3-ciclopropilaminometil-1- pirrolidinil) quinolonecarboxílico
ES2400684T3 (es) * 2006-03-09 2013-04-11 Kyorin Pharmaceutical Co., Ltd. Proceso para la producción de un derivado de pirrolidina 3,4-disustituido y el compuesto intermedio para la producción
WO2011152354A1 (ja) * 2010-05-31 2011-12-08 杏林製薬株式会社 ３－置換－４－フルオロピロリジン誘導体の製造方法
SG189469A1 (en) 2010-10-25 2013-05-31 Kyorin Seiyaku Kk Method for producing 3,4-disubstituted pyrrolidine derivative
SA112330992B1 (ar) * 2011-11-10 2015-09-13 كيورين فارماسوتيكال كو.، ليمتد صورة متبلرة من 7-{(s4، s3)-3-[(سيكلو بروبيل أمينو) ميثيل]-4-فلورو بيروليدين-1-يل}-6-فلورو-1-(2-فلورو إيثيل)- 8-ميثوكسي-4-أوكسو-1، 4-داي هيدرو كينولين-3- حمض كربوكسيلي
JP6062422B2 (ja) * 2012-03-29 2017-01-18 杏林製薬株式会社 カプセル製剤
JP6050322B2 (ja) * 2012-03-29 2016-12-21 杏林製薬株式会社 カプセル製剤
WO2014174848A1 (ja) * 2013-04-25 2014-10-30 杏林製薬株式会社 錠剤
CA2910121A1 (en) * 2013-04-25 2014-10-30 Kyorin Pharmaceutical Co., Ltd. A pharmaceutical composition comprising a 1,4-dihydroquinoline carboxylic acid a cellulosic excipient and a salting-out agent
US9603804B2 (en) 2013-04-25 2017-03-28 Kyorin Pharmaceutical Co., Ltd. Solid pharmaceutical composition
CA2965473A1 (en) * 2014-10-23 2016-04-28 Kyorin-Pharmaceutical Co., Ltd. Solid pharmaceutical composition
US20180042918A1 (en) * 2015-03-13 2018-02-15 Kyorin Pharmaceutical Co., Ltd. Respiratory infection treating agent
EP3305295A4 (en) * 2015-06-02 2019-02-20 Kyorin Pharmaceutical Co., Ltd. AQUEOUS MEDICINE
CA2987879A1 (en) 2015-06-02 2016-12-08 Kyorin Pharmaceutical Co., Ltd. Aqueous drug
JP6031216B1 (ja) * 2015-06-02 2016-11-24 杏林製薬株式会社 水性液剤
US10406149B2 (en) 2015-06-02 2019-09-10 Kyorin Pharmaceutical Co., Ltd. Aqueous liquid formulation
JP6031217B1 (ja) * 2015-06-02 2016-11-24 杏林製薬株式会社 水性液剤
CN106831795B (zh) * 2017-01-16 2018-12-21 石家庄学院 喹诺酮异土木香内酯衍生物及其制备和应用
WO2018230686A1 (ja) 2017-06-16 2018-12-20 杏林製薬株式会社 誤嚥性肺炎、肺化膿症又は肺膿瘍の治療剤
US20210137913A1 (en) 2017-06-16 2021-05-13 Kyorin Pharmaceutical Co., Ltd. Therapeutic agent for aspiration pneumonia, lung suppuration, or lung abscess

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Also Published As

Publication number Publication date
US20090176824A1 (en) 2009-07-09
AU2004272414A1 (en) 2005-03-24
EP1666477B1 (en) 2013-07-03
US8106072B2 (en) 2012-01-31
JPWO2005026147A1 (ja) 2007-11-08
US20060281779A1 (en) 2006-12-14
ES2424676T3 (es) 2013-10-07
JP4639149B2 (ja) 2011-02-23
CY1114476T1 (el) 2016-10-05
BRPI0413964B1 (pt) 2017-03-28
SG144936A1 (en) 2008-08-28
BRPI0413964A (pt) 2006-10-31
CA2536429C (en) 2012-02-14
WO2005026147A1 (ja) 2005-03-24
KR20060123096A (ko) 2006-12-01
AU2004272414B2 (en) 2009-05-28
NO20061050L (no) 2006-04-04
PT1666477E (pt) 2013-08-28
EP1666477A1 (en) 2006-06-07
EP1666477A4 (en) 2008-10-22
NZ545472A (en) 2009-09-25
BRPI0413964B8 (pt) 2021-05-25
KR101077755B1 (ko) 2011-10-27
SI1666477T1 (sl) 2013-10-30
CN1849316A (zh) 2006-10-18
CA2536429A1 (en) 2005-03-24
US7514451B2 (en) 2009-04-07
CN100410249C (zh) 2008-08-13
NO333481B1 (no) 2013-06-24
PL1666477T3 (pl) 2013-11-29

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