DK1644505T3 - Gærmodel for amyloidogen proteintoksicitet - Google Patents
Gærmodel for amyloidogen proteintoksicitetInfo
- Publication number
- DK1644505T3 DK1644505T3 DK04737685T DK04737685T DK1644505T3 DK 1644505 T3 DK1644505 T3 DK 1644505T3 DK 04737685 T DK04737685 T DK 04737685T DK 04737685 T DK04737685 T DK 04737685T DK 1644505 T3 DK1644505 T3 DK 1644505T3
- Authority
- DK
- Denmark
- Prior art keywords
- amyloidogenic protein
- yeast model
- protein toxicity
- modelling
- yeast strain
- Prior art date
Links
- 102000009091 Amyloidogenic Proteins Human genes 0.000 title abstract 3
- 108010048112 Amyloidogenic Proteins Proteins 0.000 title abstract 3
- 240000004808 Saccharomyces cerevisiae Species 0.000 title abstract 3
- 230000001988 toxicity Effects 0.000 title 1
- 231100000419 toxicity Toxicity 0.000 title 1
- 108700019146 Transgenes Proteins 0.000 abstract 1
- 230000001413 cellular effect Effects 0.000 abstract 1
- 230000004770 neurodegeneration Effects 0.000 abstract 1
- 208000015122 neurodegenerative disease Diseases 0.000 abstract 1
- 230000036542 oxidative stress Effects 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 238000012216 screening Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
- C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/37—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
- C07K14/39—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from yeasts
- C07K14/395—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from yeasts from Saccharomyces
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Mycology (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP03447184 | 2003-07-11 | ||
PCT/BE2004/000102 WO2005005640A1 (en) | 2003-07-11 | 2004-07-09 | A yeast model for amyloidogenic protein toxicity |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1644505T3 true DK1644505T3 (da) | 2008-08-18 |
Family
ID=34043034
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK04737685T DK1644505T3 (da) | 2003-07-11 | 2004-07-09 | Gærmodel for amyloidogen proteintoksicitet |
Country Status (7)
Country | Link |
---|---|
US (1) | US20060008894A1 (da) |
EP (1) | EP1644505B1 (da) |
AT (1) | ATE393230T1 (da) |
DE (1) | DE602004013319T2 (da) |
DK (1) | DK1644505T3 (da) |
ES (1) | ES2307018T3 (da) |
WO (1) | WO2005005640A1 (da) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7799535B1 (en) | 1997-12-09 | 2010-09-21 | Arch Development Corporation | Methods for identifying factors that control the folding of amyloid proteins of diverse origin |
ATE382704T1 (de) | 2001-02-15 | 2008-01-15 | Univ Chicago | Verfahren zum nachweis in hefe für mittels die proteinfaltung beeinflussen |
CN111100795A (zh) * | 2019-12-27 | 2020-05-05 | 深圳康泰生物制品股份有限公司 | 表达手足口病疫苗抗原的重组汉逊酵母细胞破碎缓冲液及其制备方法与应用 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE382704T1 (de) * | 2001-02-15 | 2008-01-15 | Univ Chicago | Verfahren zum nachweis in hefe für mittels die proteinfaltung beeinflussen |
US20030235823A1 (en) * | 2002-06-24 | 2003-12-25 | The University Of Alabama | Nucleotide sequences that code for torsin genes, torsin proteins, and methods of using the same to treat protein-aggregation |
-
2004
- 2004-07-09 ES ES04737685T patent/ES2307018T3/es not_active Expired - Lifetime
- 2004-07-09 US US10/527,472 patent/US20060008894A1/en not_active Abandoned
- 2004-07-09 EP EP04737685A patent/EP1644505B1/en not_active Expired - Lifetime
- 2004-07-09 DE DE602004013319T patent/DE602004013319T2/de not_active Expired - Lifetime
- 2004-07-09 WO PCT/BE2004/000102 patent/WO2005005640A1/en active IP Right Grant
- 2004-07-09 DK DK04737685T patent/DK1644505T3/da active
- 2004-07-09 AT AT04737685T patent/ATE393230T1/de not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
EP1644505A1 (en) | 2006-04-12 |
ES2307018T3 (es) | 2008-11-16 |
WO2005005640A1 (en) | 2005-01-20 |
US20060008894A1 (en) | 2006-01-12 |
DE602004013319D1 (de) | 2008-06-05 |
ATE393230T1 (de) | 2008-05-15 |
DE602004013319T2 (de) | 2009-07-09 |
EP1644505B1 (en) | 2008-04-23 |
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