DK1594963T3 - Proteaser - Google Patents

Proteaser

Info

Publication number: DK1594963T3
Authority: DK; Denmark
Prior art keywords: proteases; nocardiopsis; relates; animal feed; copper
Prior art date: 2003-02-07

Application number

DK04737239T

Other languages

English (en)

Inventor

Peter Rahbek Oestergaard

Maria Leonardo De

Original Assignee

Novozymes As

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-02-07

Filing date

2004-02-09

Publication date

2007-11-26

2004-02-09 Application filed by Novozymes As filed Critical Novozymes As

2007-11-26 Application granted granted Critical

2007-11-26 Publication of DK1594963T3 publication Critical patent/DK1594963T3/da

Links

102000035195 Peptidases Human genes 0.000 title abstract 7
108091005804 Peptidases Proteins 0.000 title abstract 7
239000004365 Protease Substances 0.000 title abstract 6
239000010949 copper Substances 0.000 abstract 3
RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 abstract 2
229910052802 copper Inorganic materials 0.000 abstract 2
241001134261 Brachysporiella gayana Species 0.000 abstract 1
241000223250 Metarhizium anisopliae Species 0.000 abstract 1
241000520851 Nocardiopsis alba Species 0.000 abstract 1
241000923014 Nocardiopsis dassonvillei subsp. dassonvillei Species 0.000 abstract 1
241000203616 Nocardiopsis prasina Species 0.000 abstract 1
241001221335 Nocardiopsis sp. Species 0.000 abstract 1
102000012479 Serine Proteases Human genes 0.000 abstract 1
108010022999 Serine Proteases Proteins 0.000 abstract 1
235000019730 animal feed additive Nutrition 0.000 abstract 1
239000003599 detergent Substances 0.000 abstract 1
235000019833 protease Nutrition 0.000 abstract 1
125000003607 serino group Chemical class [H]N([H])[C@]([H])(C(=O)[*])C(O[H])([H])[H] 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/58—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from fungi
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/11—Antisense
- C12N2310/111—Antisense spanning the whole gene, or a large part of it

Landscapes

Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Wood Science & Technology (AREA)
Genetics & Genomics (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Zoology (AREA)
Biochemistry (AREA)
General Health & Medical Sciences (AREA)
Microbiology (AREA)
Molecular Biology (AREA)
Biomedical Technology (AREA)
Medicinal Chemistry (AREA)
General Engineering & Computer Science (AREA)
Biotechnology (AREA)
Mycology (AREA)
Enzymes And Modification Thereof (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Detergent Compositions (AREA)
Fodder In General (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

DK04737239T 2003-02-07 2004-02-09 Proteaser DK1594963T3 (da)

Applications Claiming Priority (9)

Application Number	Priority Date	Filing Date	Title
DKPA200300173		2003-02-07
DKPA200300426		2003-03-20
DKPA200300915		2003-06-19
DKPA200300912		2003-06-19
DKPA200300914		2003-06-19
DKPA200300913		2003-06-19
DKPA200301492		2003-10-10
DKPA200301493		2003-10-10
PCT/DK2004/000090 WO2004072221A2 (en)	2003-02-07	2004-02-09	Proteases

Publications (1)

Publication Number	Publication Date
DK1594963T3 true DK1594963T3 (da)	2007-11-26

Family

ID=32873147

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK04737239T DK1594963T3 (da)	2003-02-07	2004-02-09	Proteaser

Country Status (10)

Country	Link
US (3)	US7588926B2 (da)
EP (1)	EP1594963B1 (da)
CN (1)	CN1774504B (da)
AT (1)	ATE368105T1 (da)
AU (1)	AU2004211446B2 (da)
BR (1)	BRPI0407294B1 (da)
DE (1)	DE602004007766T2 (da)
DK (1)	DK1594963T3 (da)
ES (1)	ES2291883T3 (da)
WO (1)	WO2004072221A2 (da)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6960462B2 (en) *	2000-02-08	2005-11-01	Dsm Ip Assets B.V	Use of acid-stable subtilisin proteases in animal feed
US6855548B2 (en)	2000-02-08	2005-02-15	F. Hoffman-La Roche Ag	Use of acid-stable proteases in animal feed
CN1774504B (zh) *	2003-02-07	2013-04-17	诺维信公司	蛋白酶
WO2004111222A1 (en) *	2003-06-19	2004-12-23	Novozymes A/S	Proteases
DE602004026446D1 (de) *	2003-06-19	2010-05-20	Novozymes As	Verbesserte proteasen und verfahren zu ihrer herstellung
DE602004016654D1 (de) *	2003-06-19	2008-10-30	Novozymes As	Proteasen
US20060236414A1 (en)	2003-06-19	2006-10-19	Novozymes A/S	Proteases and methods for producing them
WO2004111223A1 (en) *	2003-06-19	2004-12-23	Novozymes A/S	Proteases
ES2346654T3 (es) *	2003-06-19	2010-10-19	Novozymes A/S	Proteasas.
WO2005035747A1 (en)	2003-10-10	2005-04-21	Novozymes A/S	Protease variants
WO2005123915A1 (en) *	2004-06-21	2005-12-29	Novozymes A/S	Stably maintained multiple copies of at least two orf in the same orientation
WO2005123911A2 (en) *	2004-06-21	2005-12-29	Novozymes A/S	Proteases
DK1786908T3 (da) *	2004-08-18	2010-06-07	Bayer Cropscience Ag	Planter med forøget plastidisk aktivitet af stivelsesphosphorylerende R3-enzym
AU2007274281B2 (en)	2006-07-13	2013-01-10	Dsm Ip Assets B.V.	Use of bacterial amylases in feed for bovine animals
CN101500430B (zh)	2006-08-07	2014-02-19	诺维信公司	用于动物饲料的酶团粒
ES2577430T3 (es)	2006-08-07	2016-07-14	Novozymes A/S	Gránulos de enzima para pienso para animales
EP2089065B1 (en) *	2006-10-27	2015-01-21	E.I. Du Pont De Nemours And Company	Method for prion decontamination
EP2097510B1 (en) *	2006-12-22	2016-10-05	Novozymes A/S	Method for producing a yeast extract
US8691743B2 (en)	2008-05-14	2014-04-08	Novozymes A/S	Liquid detergent compositions
US20110081450A1 (en) *	2008-06-03	2011-04-07	Novozymes A/S	Method for Producing A Wheat Protein Hydrolysate
MX2010014091A (es) *	2008-06-20	2011-03-21	Solae Llc	Composiciones de hidrolizado de proteinas estables en condiciones acidas.
CN102325876A (zh) *	2009-02-19	2012-01-18	诺维信公司	酿造方法
KR101739326B1 (ko) *	2009-04-02	2017-05-24	노보자임스 에이/에스	젖-기반 단백질 가수분해물의 제조 방법
EP2744900B1 (en)	2011-08-19	2017-07-19	Novozymes A/S	Polypeptides having protease activity
MX350391B (es)	2011-09-22	2017-09-06	Novozymes As	Polipeptidos que poseen actividad proteasa y polinucleotidos que los codifican.
US10174301B2 (en)	2011-12-28	2019-01-08	Novozymes A/S	Methods for improving the nutritional value of the animal feed using a protease
ES2644007T3 (es)	2012-01-26	2017-11-27	Novozymes A/S	Uso de polipéptidos con actividad de proteasa en piensos para animales y en detergentes
US20150140165A1 (en)	2012-06-20	2015-05-21	Novozymes A/S	Use of polypeptides having protease activity in animal feed and detergents
ES2694765T3 (es)	2012-09-05	2018-12-27	Novozymes A/S	Polipéptidos con actividad de proteasa
US9963707B2 (en)	2012-10-03	2018-05-08	Agrivida, Inc.	Multiprotein expression cassettes
FR2998450A1 (fr) *	2012-11-26	2014-05-30	Dominique Hooreman	Utilisation d'un complexe enzymatique dans l'alimentation des animaux d'elevage
BR112015014396B1 (pt)	2012-12-21	2021-02-02	Novozymes A/S	Composição, construto de ácido nucleico ou vetor de expressão, microorganismo recombinante, métodos de melhoria do valor nutricional de uma ração animal, aditivo de ração animal, e, uso de uma ou mais proteases
EP2953481A2 (en)	2013-02-06	2015-12-16	Novozymes A/S	Use of polypeptides having protease activity in animal feed
CN106455630B (zh)	2014-06-27	2021-08-24	帝斯曼知识产权资产管理有限公司	改进动物饲料的营养价值的方法
CN104293760A (zh) *	2014-10-14	2015-01-21	夏盛（武汉）生物科技有限公司	一种多酶复合型抑泡剂及其在酒精发酵工业中的应用
US10619145B2 (en)	2014-11-04	2020-04-14	Novozymes A/S	Polypeptides having serine protease activity and polynucleotides encoding same and their application in animal feed
TW201940778A (zh)	2018-01-16	2019-10-16	日商花王股份有限公司	角質汙垢清潔劑、及角質汙垢分解能力之評估方法
EP3864036A1 (en) *	2018-10-10	2021-08-18	Novozymes A/S	Chymotrypsin inhibitor variants and the use thereof
CN110283880A (zh) *	2019-08-08	2019-09-27	天津科技大学	一种测定蛋白酶活力的新方法

Family Cites Families (57)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3668448A (en) *	1967-05-29	1972-06-06	Enakichi Hayasaka	Homopole type ac generator
GB1234445A (da) *	1967-10-03	1971-06-03
DE2004328C3 (de)	1970-01-30	1979-10-18	Nippon Kokan K.K., Tokio	Bodenkonstruktion für eine Gas-Flüssigkeits-Kontaktierkolonne
US3823072A (en) *	1970-02-19	1974-07-09	M Hooreman	Analysis of proteolytic enzymes
US3683069A (en)	1970-02-19	1972-08-08	Michel Hooreman	Enzymatic products which optimize the viscosity of mucuses and their applications
US3663069A (en) *	1970-10-07	1972-05-16	Kelsey Hayes Co	Skid control system
US3868448A (en)	1973-12-07	1975-02-25	Grace W R & Co	Method for bloat control
US3966971A (en) *	1975-01-02	1976-06-29	Grain Processing Corporation	Separation of protein from vegetable sources
US4073884A (en) *	1976-09-27	1978-02-14	W. R. Grace & Co.	Promotion of feed efficiency
DE3149457A1 (de) *	1981-12-14	1983-06-23	Henkel KGaA, 4000 Düsseldorf	Verfahren zur herstellung saurer protease und diese bildende mutanten von pilzen der gattung aspergillus
IE81141B1 (en)	1983-06-24	2000-04-05	Genencor Int	Procaryotic carbonyl hydrolases
CA1295566C (en)	1987-07-21	1992-02-11	Robert T. Garvin	Characterization and structure of genes for protease a and protease b from streptomyces griseus
FR2600340A1 (fr) *	1986-06-20	1987-12-24	Hooremam Michel	Procede de production d'un nouveau complexe proteolytique stimulant l'activite du pancreas et ses applications en zootechnie
DK564086A (da)	1986-11-25	1988-06-17	Novo Industri As	Enzymatisk detergent-additiv
JPH02255081A (ja)	1989-03-30	1990-10-15	Snow Brand Milk Prod Co Ltd	プロテアーゼ生産菌、該菌体から産生したプロテアーゼ、及びその精製方法
DK316989D0 (da)	1989-06-26	1989-06-26	Novo Nordisk As	Enzymer
EP0509985B1 (en)	1990-01-11	1994-04-13	Novo Nordisk A/S	Bacteriolytic enzyme native to a nocardiopsis strain, its production and use.
CA2063892A1 (en)	1991-03-29	1992-09-30	Susan A. Anderson	Alpha-lytic protease cleaning compositions
WO1992019729A1 (en)	1991-05-01	1992-11-12	Novo Nordisk A/S	Stabilized enzymes and detergent compositions
DE69212390T2 (de)	1991-05-01	1997-01-09	Unilever Nv	Stabilisierte Enzyme enthaltende Waschmittelzusammensetzungen
US5646028A (en) *	1991-06-18	1997-07-08	The Clorox Company	Alkaline serine protease streptomyces griseus var. alkaliphus having enhanced stability against urea or guanidine
US5811382A (en) *	1991-12-20	1998-09-22	Novo Nordisk A/S	Detergent compositions
WO1993023530A1 (en)	1992-05-19	1993-11-25	Shionogi Seiyaku Kabushiki Kaisha	Novel protease
DK81193D0 (da)	1993-07-06	1993-07-06	Novo Nordisk As	Enzym
AU1911995A (en)	1994-02-14	1995-08-29	Quaker Oats Company, The	Animal food palatability improving composition and process
EP1142485B1 (en)	1994-04-22	2008-02-27	Novozymes A/S	A method for improving the solubility of vegetable proteins
GB9416841D0 (en)	1994-08-19	1994-10-12	Finnfeeds Int Ltd	An enzyme feed additive and animal feed including it
US5877403A (en)	1994-12-30	1999-03-02	Seminis Vegetable Seeds, Inc.	Papaya ringspot virus protease gene
DK1396A (da)	1996-01-09	1996-01-09	Novo Nordisk As
US5705379A (en) *	1996-10-23	1998-01-06	Cornell Research Foundation, Inc.	Nucleotide sequences encoding a thermostable alkaline protease
US6068630A (en) *	1997-01-02	2000-05-30	St. Francis Medical Technologies, Inc.	Spine distraction implant
FI972521A (fi)	1997-06-13	1998-12-14	Cultor Oy	Menetelmä ravinnollisen tuotteen valmistamiseksi ja näin valmistettu tuote
NZ330940A (en)	1997-07-24	2000-02-28	F	Production of consensus phytases from fungal origin using computer programmes
US6835550B1 (en)	1998-04-15	2004-12-28	Genencor International, Inc.	Mutant proteins having lower allergenic response in humans and methods for constructing, identifying and producing such proteins
US6855548B2 (en) *	2000-02-08	2005-02-15	F. Hoffman-La Roche Ag	Use of acid-stable proteases in animal feed
US6960462B2 (en) *	2000-02-08	2005-11-01	Dsm Ip Assets B.V	Use of acid-stable subtilisin proteases in animal feed
DK1257175T3 (da) *	2000-02-08	2006-04-10	Dsm Ip Assets Bv	Brug af syrestabile Subtilisin Proteaser i dyrefoder.
US7630836B2 (en) *	2001-05-30	2009-12-08	The Kitasato Institute	Polynucleotides
JP4137526B2 (ja)	2002-01-23	2008-08-20	Ｔｏｔｏ株式会社	ケラチナーゼおよびその製造法
JP4114046B2 (ja)	2002-07-12	2008-07-09	川村通商株式会社	酵素脱毛処理剤および酵素脱毛法
WO2004070106A1 (ja)	2003-02-06	2004-08-19	Daiwa Kasei K.K.	獣毛繊維の防縮加工法
CN1774504B (zh)	2003-02-07	2013-04-17	诺维信公司	蛋白酶
WO2004072279A2 (en)	2003-02-07	2004-08-26	Novozymes A/S	Proteases
WO2004111222A1 (en)	2003-06-19	2004-12-23	Novozymes A/S	Proteases
WO2004111223A1 (en)	2003-06-19	2004-12-23	Novozymes A/S	Proteases
ES2346654T3 (es)	2003-06-19	2010-10-19	Novozymes A/S	Proteasas.
US20060236414A1 (en) *	2003-06-19	2006-10-19	Novozymes A/S	Proteases and methods for producing them
DE602004016654D1 (de) *	2003-06-19	2008-10-30	Novozymes As	Proteasen
DE602004026446D1 (de) *	2003-06-19	2010-05-20	Novozymes As	Verbesserte proteasen und verfahren zu ihrer herstellung
US7208310B2 (en)	2003-06-19	2007-04-24	Novozymes A/S	Proteases
AU2004270815B2 (en) *	2003-09-11	2011-06-02	Novozymes Adenium Biotech A/S	Recombinant production of antimicrobial agents
WO2005035747A1 (en) *	2003-10-10	2005-04-21	Novozymes A/S	Protease variants
WO2005123911A2 (en)	2004-06-21	2005-12-29	Novozymes A/S	Proteases
EP1766000A1 (en) *	2004-06-21	2007-03-28	Novozymes A/S	Improved methods of producing heterologous proteases
US7618801B2 (en) *	2007-10-30	2009-11-17	Danison US Inc.	Streptomyces protease
US20100093633A1 (en) *	2008-10-10	2010-04-15	Novozymes A/S	Polypeptides having antimicrobial activity
KR101739326B1 (ko) *	2009-04-02	2017-05-24	노보자임스 에이/에스	젖-기반 단백질 가수분해물의 제조 방법

2004
- 2004-02-09 CN CN2004800092012A patent/CN1774504B/zh not_active Expired - Fee Related
- 2004-02-09 DK DK04737239T patent/DK1594963T3/da active
- 2004-02-09 ES ES04737239T patent/ES2291883T3/es not_active Expired - Lifetime
- 2004-02-09 BR BRPI0407294-4A patent/BRPI0407294B1/pt not_active IP Right Cessation
- 2004-02-09 AT AT04737239T patent/ATE368105T1/de not_active IP Right Cessation
- 2004-02-09 WO PCT/DK2004/000090 patent/WO2004072221A2/en active IP Right Grant
- 2004-02-09 US US10/544,861 patent/US7588926B2/en active Active
- 2004-02-09 DE DE602004007766T patent/DE602004007766T2/de not_active Expired - Lifetime
- 2004-02-09 AU AU2004211446A patent/AU2004211446B2/en not_active Ceased
- 2004-02-09 EP EP04737239A patent/EP1594963B1/en not_active Expired - Lifetime
2009
- 2009-05-15 US US12/466,470 patent/US7906310B2/en not_active Expired - Fee Related
2011
- 2011-01-27 US US13/014,974 patent/US20110124084A1/en not_active Abandoned

Also Published As

Publication number	Publication date
AU2004211446B2 (en)	2009-05-28
ES2291883T3 (es)	2008-03-01
BRPI0407294B1 (pt)	2017-06-13
CN1774504B (zh)	2013-04-17
US7588926B2 (en)	2009-09-15
US20110124084A1 (en)	2011-05-26
EP1594963B1 (en)	2007-07-25
DE602004007766T2 (de)	2008-06-05
WO2004072221A3 (en)	2004-09-30
CN1774504A (zh)	2006-05-17
WO2004072221A2 (en)	2004-08-26
AU2004211446A1 (en)	2004-08-26
US7906310B2 (en)	2011-03-15
BRPI0407294A (pt)	2006-02-07
US20060147499A1 (en)	2006-07-06
EP1594963A2 (en)	2005-11-16
US20090238922A1 (en)	2009-09-24
ATE368105T1 (de)	2007-08-15
DE602004007766D1 (de)	2007-09-06

Publication	Publication Date	Title
DK1594963T3 (da)	2007-11-26	Proteaser
MX355362B (es)	2018-04-17	Variantes de proteasa.
ATE408682T1 (de)	2008-10-15	Proteasen
WO2004072279A3 (en)	2004-10-28	Proteases
IN2012DN03824A (da)	2015-08-28
ATE519842T1 (de)	2011-08-15	Trichoderma reesei-glucoamylase und homologe davon
ATE533839T1 (de)	2011-12-15	Phytasenvarianten
ATE491788T1 (de)	2011-01-15	Proteasevarianten
EP2519251A4 (en)	2013-08-28	ISOLATED CLEANED BOWMAN BIRK PROTEASE HEMMER PROTEINS FROM A SOYA PROCESSING STREAM
SG151315A1 (en)	2009-04-30	Human glp-1 mimetibodies, compositions, methods and uses
BRPI0512341A (pt)	2008-03-04	polipeptìdeo isolado tendo atividade de protease, seqüência de ácido nucleico isolada, construto de ácido nucleico, vetor de expressão, célula hospedeira recombinante, planta ou parte vegetal transgênica, animal não humano transgênico, uso de pelo menos uma protease, métodos para produzir um polipeptìdeo, para melhorar o valor nutricional de uma ração animal e para tratar proteìnas, ração animal, e, aditivo de ração animal
MX2010004371A (es)	2010-05-20	Proteasa de streptomyces.
ATE530643T1 (de)	2011-11-15	Säureaktive fungale protease
TW200938526A (en)	2009-09-16	Sulfur compounds as inhibitors of hepatitis C virus NS3 serine protease
DE602004027376D1 (de)	2010-07-08	Proteasen
UA93658C2 (en)	2011-03-10	Cell surface glycoprotein
HUP0500383A2 (hu)	2005-08-29	Mikroorganizmusok és eljárások pantotenát fokozott termelésére
DK1664102T3 (da)	2012-02-27	Isoleret photoprotein mtclytin, samt dets anvendelse
UA80869C2 (en)	2007-11-12	Phosphonic acid compounds as serine proteinase inhibitors
MXPA06000507A (es)	2006-04-05	Pirazolinas como antagonistas de par-1 para el tratamiento de enfermedades cardiovasculares.
NO20053575L (no)	2005-09-23	Metallprotease proteiner
WO2003097593A3 (en)	2004-07-08	Protease inhibitors
TH53171B (th)	2002-09-23	การใช้โปรตีเอสที่เสถียรต่อกรดในอาหารสัตว์
WO2004053117A3 (en)	2004-09-23	Serine protease
WO2003072724A3 (en)	2005-04-07	Human analogs of murine deubiquitinating protease genes