DK1578774T3 - Oprensning af immunoglobuliner - Google Patents
Oprensning af immunoglobulinerInfo
- Publication number
- DK1578774T3 DK1578774T3 DK03754635.5T DK03754635T DK1578774T3 DK 1578774 T3 DK1578774 T3 DK 1578774T3 DK 03754635 T DK03754635 T DK 03754635T DK 1578774 T3 DK1578774 T3 DK 1578774T3
- Authority
- DK
- Denmark
- Prior art keywords
- immunoglobulines
- purification
- Prior art date
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/32—Bonded phase chromatography
- B01D15/325—Reversed phase
- B01D15/327—Reversed phase with hydrophobic interaction
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/20—Partition-, reverse-phase or hydrophobic interaction chromatography
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/32—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/40—Immunoglobulins specific features characterized by post-translational modification
- C07K2317/41—Glycosylation, sialylation, or fucosylation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/55—Fab or Fab'
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Analytical Chemistry (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US41153702P | 2002-09-18 | 2002-09-18 | |
PCT/US2003/029103 WO2004026891A2 (en) | 2002-09-18 | 2003-09-15 | Protein purification |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1578774T3 true DK1578774T3 (da) | 2014-02-03 |
Family
ID=32030687
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK03754635.5T DK1578774T3 (da) | 2002-09-18 | 2003-09-15 | Oprensning af immunoglobuliner |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP1578774B1 (da) |
AU (1) | AU2003272454A1 (da) |
DK (1) | DK1578774T3 (da) |
WO (1) | WO2004026891A2 (da) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BRPI0709726A2 (pt) | 2006-04-05 | 2011-07-26 | Abbott Biotechnology Ltd. | purificaÇço de anticorpo |
CN1908006B (zh) * | 2006-08-07 | 2010-05-12 | 陈志南 | 一种快速纯化制备Fab片段抗体的工艺方法 |
SI2473617T1 (sl) * | 2009-09-01 | 2020-07-31 | F. Hoffmann-La Roche Ag | Izboljšano prečiščevanje beljakovin z modificirano elucijo beljakovine A |
US9062106B2 (en) | 2011-04-27 | 2015-06-23 | Abbvie Inc. | Methods for controlling the galactosylation profile of recombinantly-expressed proteins |
US9181572B2 (en) | 2012-04-20 | 2015-11-10 | Abbvie, Inc. | Methods to modulate lysine variant distribution |
US9150645B2 (en) | 2012-04-20 | 2015-10-06 | Abbvie, Inc. | Cell culture methods to reduce acidic species |
US9067990B2 (en) | 2013-03-14 | 2015-06-30 | Abbvie, Inc. | Protein purification using displacement chromatography |
US9512214B2 (en) | 2012-09-02 | 2016-12-06 | Abbvie, Inc. | Methods to control protein heterogeneity |
CA2905010A1 (en) | 2013-03-12 | 2014-09-18 | Abbvie Inc. | Human antibodies that bind human tnf-alpha and methods of preparing the same |
US10023608B1 (en) | 2013-03-13 | 2018-07-17 | Amgen Inc. | Protein purification methods to remove impurities |
US9499614B2 (en) | 2013-03-14 | 2016-11-22 | Abbvie Inc. | Methods for modulating protein glycosylation profiles of recombinant protein therapeutics using monosaccharides and oligosaccharides |
US9017687B1 (en) | 2013-10-18 | 2015-04-28 | Abbvie, Inc. | Low acidic species compositions and methods for producing and using the same using displacement chromatography |
EP3052640A2 (en) | 2013-10-04 | 2016-08-10 | AbbVie Inc. | Use of metal ions for modulation of protein glycosylation profiles of recombinant proteins |
US9181337B2 (en) | 2013-10-18 | 2015-11-10 | Abbvie, Inc. | Modulated lysine variant species compositions and methods for producing and using the same |
US9085618B2 (en) | 2013-10-18 | 2015-07-21 | Abbvie, Inc. | Low acidic species compositions and methods for producing and using the same |
WO2015073884A2 (en) | 2013-11-15 | 2015-05-21 | Abbvie, Inc. | Glycoengineered binding protein compositions |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5652348A (en) * | 1994-09-23 | 1997-07-29 | Massey University | Chromatographic resins and methods for using same |
US20040018573A1 (en) * | 2002-04-18 | 2004-01-29 | Power Scott D | Production of functional antibodies in filamentous fungi |
-
2003
- 2003-09-15 EP EP03754635.5A patent/EP1578774B1/en not_active Expired - Lifetime
- 2003-09-15 DK DK03754635.5T patent/DK1578774T3/da active
- 2003-09-15 AU AU2003272454A patent/AU2003272454A1/en not_active Abandoned
- 2003-09-15 WO PCT/US2003/029103 patent/WO2004026891A2/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
EP1578774A2 (en) | 2005-09-28 |
EP1578774B1 (en) | 2013-11-06 |
EP1578774A4 (en) | 2010-08-04 |
WO2004026891A2 (en) | 2004-04-01 |
AU2003272454A1 (en) | 2004-04-08 |
WO2004026891A3 (en) | 2009-07-23 |
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