DK1572615T3 - Fremgangsmåde til syntese af peptider indeholdende en 4-hydroxyprolin-substruktur - Google Patents

Fremgangsmåde til syntese af peptider indeholdende en 4-hydroxyprolin-substruktur

Info

Publication number: DK1572615T3
Authority: DK; Denmark
Prior art keywords: hydroxyproline; substructure; synthesis; peptides containing; sub
Prior art date: 2002-12-12

Application number

DK03782373.9T

Other languages

English (en)

Inventor

Bernhard Wietfeld

Walter Prikoszovich

Dr Bernhard Erb

Werner Pachinger

Original Assignee

Novartis Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-12-12

Filing date

2003-12-11

Publication date

2010-06-14

2002-12-12 Priority claimed from GB0229020A external-priority patent/GB0229020D0/en

2002-12-16 Priority claimed from GB0229280A external-priority patent/GB0229280D0/en

2003-12-11 Application filed by Novartis Ag filed Critical Novartis Ag

2010-06-14 Application granted granted Critical

2010-06-14 Publication of DK1572615T3 publication Critical patent/DK1572615T3/da

Links

238000000034 method Methods 0.000 title abstract 3
102000004196 processed proteins & peptides Human genes 0.000 title abstract 2
108090000765 processed proteins & peptides Proteins 0.000 title abstract 2
PMMYEEVYMWASQN-DMTCNVIQSA-N Hydroxyproline Chemical compound O[C@H]1CN[C@H](C(O)=O)C1 PMMYEEVYMWASQN-DMTCNVIQSA-N 0.000 title 1
230000015572 biosynthetic process Effects 0.000 title 1
PMMYEEVYMWASQN-UHFFFAOYSA-N dl-hydroxyproline Natural products OC1C[NH2+]C(C([O-])=O)C1 PMMYEEVYMWASQN-UHFFFAOYSA-N 0.000 title 1
229960002591 hydroxyproline Drugs 0.000 title 1
238000003786 synthesis reaction Methods 0.000 title 1
150000001875 compounds Chemical class 0.000 abstract 1
239000000543 intermediate Substances 0.000 abstract 1
238000004519 manufacturing process Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/15—Preparation of carboxylic acids or their salts, halides or anhydrides by reaction of organic compounds with carbon dioxide, e.g. Kolbe-Schmitt synthesis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C65/01—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing hydroxy or O-metal groups
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Oil, Petroleum & Natural Gas (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Peptides Or Proteins (AREA)
Pyrrole Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

DK03782373.9T 2002-12-12 2003-12-11 Fremgangsmåde til syntese af peptider indeholdende en 4-hydroxyprolin-substruktur DK1572615T3 (da)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
GB0229020A GB0229020D0 (en)	2002-12-12	2002-12-12	Organic compounds
GB0229280A GB0229280D0 (en)	2002-12-16	2002-12-16	Organic compounds
PCT/EP2003/014082 WO2004052817A1 (en)	2002-12-12	2003-12-11	Process for peptide synthesis of peptides containing a 4-hydroxy-proline substructure

Publications (1)

Publication Number	Publication Date
DK1572615T3 true DK1572615T3 (da)	2010-06-14

Family

ID=32510405

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK03782373.9T DK1572615T3 (da)	2002-12-12	2003-12-11	Fremgangsmåde til syntese af peptider indeholdende en 4-hydroxyprolin-substruktur

Country Status (24)

Country	Link
US (3)	US7294722B2 (da)
EP (1)	EP1572615B8 (da)
JP (2)	JP4796303B2 (da)
KR (1)	KR101018491B1 (da)
AT (1)	ATE461173T1 (da)
AU (1)	AU2003290019B2 (da)
BR (2)	BR0317176A (da)
CA (1)	CA2509363C (da)
CO (1)	CO5700810A2 (da)
CY (1)	CY1110639T1 (da)
DE (1)	DE60331770D1 (da)
DK (1)	DK1572615T3 (da)
EC (1)	ECSP055846A (da)
ES (1)	ES2341336T3 (da)
HK (1)	HK1085459A1 (da)
IL (1)	IL168866A (da)
MX (1)	MXPA05006267A (da)
NO (1)	NO331836B1 (da)
NZ (1)	NZ540441A (da)
PL (1)	PL206914B1 (da)
PT (1)	PT1572615E (da)
RU (1)	RU2392265C2 (da)
SI (1)	SI1572615T1 (da)
WO (1)	WO2004052817A1 (da)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE4306839A1 (de) *	1993-03-05	1994-09-08	Bayer Ernst Prof Dr	Tritylgruppe enthaltendes Festphasensystem, Verfahren zu seiner Herstellung und seine Verwendung in Festphasenreaktionen
MY147327A (en)	1995-06-29	2012-11-30	Novartis Ag	Somatostatin peptides
GB9625167D0 (en) *	1996-12-04	1997-01-22	Sandoz Ltd	Organic compounds
JP2002510319A (ja) *	1997-07-01	2002-04-02	アイシス・ファーマシューティカルス・インコーポレーテッド	オリゴヌクレオチドの消化管を介したデリバリーのための組成物及び方法
GB0018891D0 (en) *	2000-08-01	2000-09-20	Novartis Ag	Organic compounds

2003
- 2003-12-11 AU AU2003290019A patent/AU2003290019B2/en not_active Expired
- 2003-12-11 PL PL375821A patent/PL206914B1/pl unknown
- 2003-12-11 WO PCT/EP2003/014082 patent/WO2004052817A1/en active Application Filing
- 2003-12-11 ES ES03782373T patent/ES2341336T3/es not_active Expired - Lifetime
- 2003-12-11 BR BR0317176-0A patent/BR0317176A/pt not_active IP Right Cessation
- 2003-12-11 KR KR1020057010600A patent/KR101018491B1/ko active IP Right Grant
- 2003-12-11 CA CA2509363A patent/CA2509363C/en not_active Expired - Lifetime
- 2003-12-11 RU RU2005121664/04A patent/RU2392265C2/ru active
- 2003-12-11 PT PT03782373T patent/PT1572615E/pt unknown
- 2003-12-11 DE DE60331770T patent/DE60331770D1/de not_active Expired - Lifetime
- 2003-12-11 DK DK03782373.9T patent/DK1572615T3/da active
- 2003-12-11 AT AT03782373T patent/ATE461173T1/de active
- 2003-12-11 SI SI200331800T patent/SI1572615T1/sl unknown
- 2003-12-11 EP EP03782373A patent/EP1572615B8/en not_active Expired - Lifetime
- 2003-12-11 US US10/538,028 patent/US7294722B2/en not_active Expired - Lifetime
- 2003-12-11 BR BRPI0317176-0A patent/BRPI0317176B1/pt unknown
- 2003-12-11 MX MXPA05006267A patent/MXPA05006267A/es active IP Right Grant
- 2003-12-11 NZ NZ540441A patent/NZ540441A/en not_active IP Right Cessation
- 2003-12-11 JP JP2004558073A patent/JP4796303B2/ja not_active Expired - Lifetime
2005
- 2005-05-30 IL IL168866A patent/IL168866A/en active IP Right Grant
- 2005-06-09 EC EC2005005846A patent/ECSP055846A/es unknown
- 2005-06-14 CO CO05057286A patent/CO5700810A2/es active IP Right Grant
- 2005-07-11 NO NO20053374A patent/NO331836B1/no not_active IP Right Cessation
2006
- 2006-03-10 HK HK06103122.9A patent/HK1085459A1/xx not_active IP Right Cessation
2007
- 2007-08-16 US US11/839,565 patent/US7449587B2/en not_active Expired - Lifetime
2008
- 2008-08-25 US US12/197,657 patent/US20080312456A1/en not_active Abandoned
2010
- 2010-04-05 JP JP2010086682A patent/JP5249276B2/ja not_active Expired - Lifetime
- 2010-05-14 CY CY20101100426T patent/CY1110639T1/el unknown

Also Published As

Publication number	Publication date
CA2509363C (en)	2012-04-24
SI1572615T1 (sl)	2010-06-30
DE60331770D1 (de)	2010-04-29
EP1572615B1 (en)	2010-03-17
US7449587B2 (en)	2008-11-11
AU2003290019A1 (en)	2004-06-30
NO331836B1 (no)	2012-04-16
NO20053374L (no)	2005-09-12
PL375821A1 (en)	2005-12-12
IL168866A (en)	2010-12-30
EP1572615A1 (en)	2005-09-14
HK1085459A1 (en)	2006-08-25
JP2010209077A (ja)	2010-09-24
BRPI0317176B1 (pt)	2018-03-13
ATE461173T1 (de)	2010-04-15
PT1572615E (pt)	2010-04-14
NO20053374D0 (no)	2005-07-11
US20080312456A1 (en)	2008-12-18
ECSP055846A (es)	2005-09-20
EP1572615B8 (en)	2010-07-14
JP5249276B2 (ja)	2013-07-31
RU2005121664A (ru)	2006-02-27
ES2341336T3 (es)	2010-06-18
KR101018491B1 (ko)	2011-03-03
US20060189814A1 (en)	2006-08-24
US7294722B2 (en)	2007-11-13
KR20050085543A (ko)	2005-08-29
WO2004052817A1 (en)	2004-06-24
JP2006509796A (ja)	2006-03-23
MXPA05006267A (es)	2005-08-19
JP4796303B2 (ja)	2011-10-19
RU2392265C2 (ru)	2010-06-20
US20080021225A1 (en)	2008-01-24
CO5700810A2 (es)	2006-11-30
PL206914B1 (pl)	2010-10-29
AU2003290019B2 (en)	2007-09-27
CY1110639T1 (el)	2015-04-29
NZ540441A (en)	2007-10-26
BR0317176A (pt)	2005-10-25
CA2509363A1 (en)	2004-06-24

Publication	Publication Date	Title
NO20031687D0 (no)	2003-04-11	Veksthormonsekretagoger
DK2100889T3 (da)	2011-08-08	Fremgangsmåde til fremstilling af 3-halo-4,5-dihydro-1H-pyrazol
BR0307432B1 (pt)	2013-09-10	difluormetiltiazolilcarboxanilidas
ATE452882T1 (de)	2010-01-15	Herstellung von quetiapin
DK1831239T3 (da)	2010-06-28	Fremgangsmåde til fremstilling af 17-hydroxy-6 beta, 7 beta, 15 beta, 16 beta-bismethylen-17alpha-pregn-4-en-3-on-21-carboxylsyre-lambda-lacton og nøgle-mellemprodukter til denne fremgangsmåde
GB0327323D0 (en)	2003-12-31	Novel pharmaceuticals
MX2008000011A (es)	2008-03-26	Procesos para preparar derivados de pirazol-o-glucosido y nuevos intermediarios de dichos procesos.
DK1572615T3 (da)	2010-06-14	Fremgangsmåde til syntese af peptider indeholdende en 4-hydroxyprolin-substruktur
DE60306636D1 (de)	2006-08-17	Wachstumhormonsekretionsförderer
WO2004024681A3 (fr)	2004-07-01	NOUVEAUX COMPOSES COMPRENANT UN GROUPEMENT THIOCARBONYLSULFANYLE UTILES POUR LA SYNTHESE DE COMPOSES α-PERFLUOROALKYLAMINES PAR VOIE RADICALAIRE
DE50303586D1 (de)	2006-07-06	Methylthiophencarboxanilide
DK1250335T3 (da)	2005-11-14	Fremgangsmåde og mellemprodukter til fremstilling af imidazopyridiner
DE60329721D1 (de)	2009-11-26	Regiospezifische synthese von nikotinderivaten
ATE417055T1 (de)	2008-12-15	Steroid modifizierte solatriosen
TW200420552A (en)	2004-10-16	Dihydro-furan-2-one derivatives, their intermediates and methods of manufacture
WO2005012276A3 (fr)	2005-06-09	Intermediaires de synthese d’inhibiteurs fluores de proteases aspartiques
DK1392652T3 (da)	2006-07-24	Fremgangsmåde til fremstilling af 1,3-disubstituerede 2-nitroguanidiner
ATE453623T1 (de)	2010-01-15	Synthese von dipeptidanaloga