DK1545553T3 - Anvendelse af alkylphosphocholiner i kombination med antitumormedikamenter - Google Patents

Anvendelse af alkylphosphocholiner i kombination med antitumormedikamenter

Info

Publication number: DK1545553T3
Authority: DK; Denmark
Prior art keywords: alkylphosphocholines; combination; antitumor drugs; antitumor; drugs
Prior art date: 2002-07-30

Application number

DK03766336.6T

Other languages

English (en)

Inventor

Herbert Sindermann

Juergen Engel

Eckhard Guenther

Original Assignee

Aeterna Zentaris Gmbh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-07-30

Filing date

2003-07-29

Publication date

2011-09-12

2003-07-29 Application filed by Aeterna Zentaris Gmbh filed Critical Aeterna Zentaris Gmbh

2011-09-12 Application granted granted Critical

2011-09-12 Publication of DK1545553T3 publication Critical patent/DK1545553T3/da

Links

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
- A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents

DK03766336.6T 2002-07-30 2003-07-29 Anvendelse af alkylphosphocholiner i kombination med antitumormedikamenter DK1545553T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US39961502P	2002-07-30	2002-07-30
PCT/EP2003/008346 WO2004012744A1 (de)	2002-07-30	2003-07-29	Anwendung von alkylphosphocholinen in kombination mit antitumormedikamenten

Publications (1)

Publication Number	Publication Date
DK1545553T3 true DK1545553T3 (da)	2011-09-12

Family

ID=31495746

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK03766336.6T DK1545553T3 (da)	2002-07-30	2003-07-29	Anvendelse af alkylphosphocholiner i kombination med antitumormedikamenter

Country Status (27)

Country	Link
US (3)	US8389497B2 (da)
EP (2)	EP2301551A1 (da)
JP (1)	JP2005535688A (da)
KR (3)	KR20110102485A (da)
CN (1)	CN1302780C (da)
AR (1)	AR040717A1 (da)
AT (1)	ATE516036T1 (da)
AU (2)	AU2003253350B2 (da)
BR (1)	BR0313048A (da)
CA (1)	CA2493023C (da)
CY (1)	CY1111902T1 (da)
DK (1)	DK1545553T3 (da)
ES (1)	ES2369535T3 (da)
HK (1)	HK1080751A1 (da)
HR (1)	HRP20050184B1 (da)
IL (1)	IL166329A (da)
MX (1)	MXPA05001203A (da)
NO (1)	NO335196B1 (da)
NZ (1)	NZ538428A (da)
PL (1)	PL375493A1 (da)
PT (1)	PT1545553E (da)
RU (1)	RU2005105693A (da)
SI (1)	SI1545553T1 (da)
TW (1)	TWI332007B (da)
UA (1)	UA82322C2 (da)
WO (1)	WO2004012744A1 (da)
ZA (1)	ZA200500453B (da)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP2005535688A (ja)	2002-07-30	2005-11-24	ツェンタリスゲゼルシャフトミットベシュレンクテルハフツング	抗腫瘍医薬との組合せにおけるアルキルホスホコリンの使用
US8383605B2 (en)	2002-07-30	2013-02-26	Aeterna Zentaris Gmbh	Use of alkylphosphocholines in combination with antimetabolites for the treatment of benign and malignant oncoses in humans and mammals
WO2006081452A2 (en) *	2005-01-28	2006-08-03	Robert Birch	Co-administration of perifosine with chemotherapeutics
RU2469727C2 (ru)	2005-12-19	2012-12-20	Этерна Центарис ГмбХ	Способ лечения или профилактики заболеваний и/или патофизиологических состояний, вызванных микроорганизмами, посредством производных алкилфосфолипидов
UA99434C2 (ru) *	2005-12-19	2012-08-27	Аетерна Центаріс Гмбх	Применение производных алкилфосфолипидов со сниженной цитотоксичностью
EP1800684A1 (en) *	2005-12-20	2007-06-27	Zentaris GmbH	Novel alkyl phospholipid derivatives and uses thereof
US8703179B2 (en)	2006-05-11	2014-04-22	Kimberly-Clark Worldwide, Inc.	Mucosal formulation
MX2010001244A (es) *	2007-07-30	2010-08-31	Ardea Biosciences Inc	Derivados de n-(arilamino) sulfonamidas que incluyen polimorfos como inhibidores de mek asi como composiciones, metodos de uso y de preparacion de los mismos.
MX2011006167A (es) *	2008-12-11	2011-07-28	Abraxis Bioscience Llc	Combinaciones y modos de administracion de agentes terapeuticos y terapia de combinacion.
CA2794513A1 (en)	2010-03-31	2011-10-06	Aeterna Zentaris Gmbh	Perifosine and capecitabine as a combined treatment for cancer

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ATE136783T1 (de) *	1991-07-04	1996-05-15	Asta Medica Ag	Arzneimittel mit antineoplastischer wirkung enthaltend als wirkstoff octadecyl-(2-(n- methylpiperidino)-ethyl>-phosphat und verfahren zu dessen herstellung
US5942639A (en) *	1991-07-04	1999-08-24	Asta Medica Aktiengesellschaft	Process for the preparation of alkylphosphocholines and the production thereof in pure form
US6172050B1 (en) *	1992-07-11	2001-01-09	Asta Medica Aktiengesellschaft	Phospholipid derivatives
JP3079993B2 (ja) *	1996-03-27	2000-08-21	日本電気株式会社	真空マイクロデバイスおよびその製造方法
DE19650778C2 (de) *	1996-12-06	2001-01-04	Asta Medica Ag	Verwendung von Dopaminrezeptor-Antagonisten in der palliativen Tumortherapie
TR200001717T2 (tr)	1998-01-22	2000-11-21	Asta Medica Aktiengesellschaft	Leishmaniasis tedavisinde miltefosin ihtiva eden ve ağızdan alınan katı farmasötik bileşimler.
EP1135193B1 (de) *	1998-12-04	2002-10-30	Max-Delbrück-Centrum Für Molekulare Medizin	Mittel zur tumortherapie auf liposomenbasis, die tamoxifen enthalten
CA2356736A1 (en)	1998-12-21	2000-06-29	Inkeysa. S.A.	Use of etherlysophospholipids as antiinflammatory agents
CN104274442A (zh) *	2001-02-19	2015-01-14	诺华股份有限公司	癌症的治疗
WO2002076472A2 (en) *	2001-03-23	2002-10-03	Shire Biochem Inc.	Pharmaceutical combinations for the treatment of cancer comprising dioxolane nucleoside analogs
WO2003005522A1 (es)	2001-07-04	2003-01-16	Acuna Arturo	Tapones para sellado de ductos para redes electricas, telefonicas y de fibra optica.
SI1461083T1 (sl) *	2002-01-02	2006-08-31	Nerviano Medical Sciences Srl	Kombinirana terapija proti tumorjem na osnovi substituiranih akriloil distamicinskih derivatov in inhibitorjev protein-kinaze (serin/treonin-kinaze)
JP2005535688A (ja)	2002-07-30	2005-11-24	ツェンタリスゲゼルシャフトミットベシュレンクテルハフツング	抗腫瘍医薬との組合せにおけるアルキルホスホコリンの使用
WO2005000318A2 (en) *	2003-06-23	2005-01-06	Neopharm, Inc.	Method of inducing apoptosis and inhibiting cardiolipin synthesis
WO2006081452A2 (en)	2005-01-28	2006-08-03	Robert Birch	Co-administration of perifosine with chemotherapeutics
UA99434C2 (ru)	2005-12-19	2012-08-27	Аетерна Центаріс Гмбх	Применение производных алкилфосфолипидов со сниженной цитотоксичностью
CA2794513A1 (en)	2010-03-31	2011-10-06	Aeterna Zentaris Gmbh	Perifosine and capecitabine as a combined treatment for cancer

2003
- 2003-07-29 JP JP2004525354A patent/JP2005535688A/ja active Pending
- 2003-07-29 PL PL03375493A patent/PL375493A1/xx unknown
- 2003-07-29 AR AR20030102710A patent/AR040717A1/es unknown
- 2003-07-29 CA CA2493023A patent/CA2493023C/en not_active Expired - Lifetime
- 2003-07-29 AT AT03766336T patent/ATE516036T1/de active
- 2003-07-29 RU RU2005105693/15A patent/RU2005105693A/ru unknown
- 2003-07-29 NZ NZ538428A patent/NZ538428A/en not_active IP Right Cessation
- 2003-07-29 ES ES03766336T patent/ES2369535T3/es not_active Expired - Lifetime
- 2003-07-29 WO PCT/EP2003/008346 patent/WO2004012744A1/de active Application Filing
- 2003-07-29 KR KR1020117017914A patent/KR20110102485A/ko active Application Filing
- 2003-07-29 UA UAA200500510A patent/UA82322C2/uk unknown
- 2003-07-29 EP EP10010451A patent/EP2301551A1/de not_active Withdrawn
- 2003-07-29 EP EP03766336A patent/EP1545553B1/de not_active Expired - Lifetime
- 2003-07-29 CN CNB038181010A patent/CN1302780C/zh not_active Expired - Fee Related
- 2003-07-29 PT PT03766336T patent/PT1545553E/pt unknown
- 2003-07-29 MX MXPA05001203A patent/MXPA05001203A/es active IP Right Grant
- 2003-07-29 KR KR1020057001510A patent/KR101066804B1/ko active IP Right Grant
- 2003-07-29 DK DK03766336.6T patent/DK1545553T3/da active
- 2003-07-29 TW TW092120705A patent/TWI332007B/zh not_active IP Right Cessation
- 2003-07-29 AU AU2003253350A patent/AU2003253350B2/en not_active Ceased
- 2003-07-29 KR KR1020127034433A patent/KR20130016413A/ko not_active Application Discontinuation
- 2003-07-29 BR BR0313048-7A patent/BR0313048A/pt not_active IP Right Cessation
- 2003-07-29 SI SI200332027T patent/SI1545553T1/sl unknown
- 2003-07-30 US US10/632,187 patent/US8389497B2/en not_active Expired - Lifetime
2005
- 2005-01-17 IL IL166329A patent/IL166329A/en not_active IP Right Cessation
- 2005-01-18 ZA ZA2005/00453A patent/ZA200500453B/en unknown
- 2005-02-25 NO NO20051040A patent/NO335196B1/no not_active IP Right Cessation
- 2005-02-25 HR HRP20050184AA patent/HRP20050184B1/hr not_active IP Right Cessation
2006
- 2006-01-20 HK HK06100926A patent/HK1080751A1/xx not_active IP Right Cessation
2008
- 2008-07-10 AU AU2008203060A patent/AU2008203060B2/en not_active Ceased
2010
- 2010-03-31 US US12/751,454 patent/US8551977B2/en not_active Expired - Lifetime
- 2010-03-31 US US12/751,608 patent/US8507710B2/en not_active Expired - Fee Related
2011
- 2011-09-30 CY CY20111100944T patent/CY1111902T1/el unknown

Also Published As

Publication number	Publication date
AR040717A1 (es)	2005-04-20
SI1545553T1 (sl)	2011-09-30
US8551977B2 (en)	2013-10-08
PL375493A1 (en)	2005-11-28
CN1671397A (zh)	2005-09-21
NO335196B1 (no)	2014-10-20
EP1545553A1 (de)	2005-06-29
NO20051040L (no)	2005-02-25
PT1545553E (pt)	2011-09-12
KR20130016413A (ko)	2013-02-14
HRP20050184A2 (en)	2005-04-30
CA2493023C (en)	2012-01-31
WO2004012744A1 (de)	2004-02-12
IL166329A0 (en)	2006-01-15
US8389497B2 (en)	2013-03-05
AU2003253350B2 (en)	2008-06-26
ZA200500453B (en)	2005-08-31
US20040097470A1 (en)	2004-05-20
CN1302780C (zh)	2007-03-07
AU2008203060A1 (en)	2008-07-31
UA82322C2 (uk)	2008-04-10
MXPA05001203A (es)	2005-06-08
TW200404073A (en)	2004-03-16
CY1111902T1 (el)	2015-11-04
AU2008203060B2 (en)	2011-04-21
HRP20050184B1 (hr)	2014-04-11
NZ538428A (en)	2006-09-29
IL166329A (en)	2012-08-30
ATE516036T1 (de)	2011-07-15
BR0313048A (pt)	2005-06-14
KR20110102485A (ko)	2011-09-16
JP2005535688A (ja)	2005-11-24
US8507710B2 (en)	2013-08-13
CA2493023A1 (en)	2004-02-12
AU2003253350A1 (en)	2004-02-23
KR101066804B1 (ko)	2011-09-22
US20100189784A1 (en)	2010-07-29
ES2369535T3 (es)	2011-12-01
RU2005105693A (ru)	2005-07-10
EP1545553B1 (de)	2011-07-13
EP2301551A1 (de)	2011-03-30
US20100190738A1 (en)	2010-07-29
TWI332007B (en)	2010-10-21
KR20050026028A (ko)	2005-03-14
HK1080751A1 (en)	2006-05-04

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