DK1533376T3 - Nye aldolaser og fremgangsmåde til fremstilling af substitueret alfa-ketosyre - Google Patents

Nye aldolaser og fremgangsmåde til fremstilling af substitueret alfa-ketosyre

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Publication number
DK1533376T3
DK1533376T3 DK03792838.9T DK03792838T DK1533376T3 DK 1533376 T3 DK1533376 T3 DK 1533376T3 DK 03792838 T DK03792838 T DK 03792838T DK 1533376 T3 DK1533376 T3 DK 1533376T3
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DK
Denmark
Prior art keywords
processes
keto acid
preparing substituted
substituted alpha
novel
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Application number
DK03792838.9T
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English (en)
Inventor
Masakazu Sugiyama
Kunihiko Watanabe
Original Assignee
Ajinomoto Kk
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Application filed by Ajinomoto Kk filed Critical Ajinomoto Kk
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Publication of DK1533376T3 publication Critical patent/DK1533376T3/da

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/10—Nitrogen as only ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/42—Hydroxy-carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/44—Polycarboxylic acids
    • C12P7/50—Polycarboxylic acids having keto groups, e.g. 2-ketoglutaric acid

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Lubricants (AREA)
DK03792838.9T 2002-08-26 2003-08-26 Nye aldolaser og fremgangsmåde til fremstilling af substitueret alfa-ketosyre DK1533376T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2002245980 2002-08-26
JP2003171299 2003-06-16
PCT/JP2003/010750 WO2004018672A1 (ja) 2002-08-26 2003-08-26 新規アルドラーゼおよび置換α−ケト酸の製造方法

Publications (1)

Publication Number Publication Date
DK1533376T3 true DK1533376T3 (da) 2010-07-19

Family

ID=31949581

Family Applications (1)

Application Number Title Priority Date Filing Date
DK03792838.9T DK1533376T3 (da) 2002-08-26 2003-08-26 Nye aldolaser og fremgangsmåde til fremstilling af substitueret alfa-ketosyre

Country Status (12)

Country Link
US (6) US7351569B2 (da)
EP (3) EP1533376B1 (da)
JP (2) JP4670347B2 (da)
KR (1) KR100741650B1 (da)
CN (2) CN1678742B (da)
AT (1) ATE463568T1 (da)
AU (1) AU2003261722A1 (da)
CA (2) CA2714881C (da)
DE (1) DE60332026D1 (da)
DK (1) DK1533376T3 (da)
RU (1) RU2307871C2 (da)
WO (1) WO2004018672A1 (da)

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EP1533376A4 (en) 2006-09-06
CN103525847A (zh) 2014-01-22
DE60332026D1 (de) 2010-05-20
RU2307871C2 (ru) 2007-10-10
RU2005108605A (ru) 2005-10-27
JP4670347B2 (ja) 2011-04-13
KR20050058516A (ko) 2005-06-16
US8058038B2 (en) 2011-11-15
EP1533376B1 (en) 2010-04-07
US8697416B2 (en) 2014-04-15
US20100279365A1 (en) 2010-11-04
CA2714881A1 (en) 2004-03-04
CN1678742A (zh) 2005-10-05
EP2210943A1 (en) 2010-07-28
US20050153405A1 (en) 2005-07-14
AU2003261722A1 (en) 2004-03-11
WO2004018672A1 (ja) 2004-03-04
CA2484871A1 (en) 2004-03-04
US7351569B2 (en) 2008-04-01
US8273556B2 (en) 2012-09-25
CN1678742B (zh) 2013-07-17
US20120040416A1 (en) 2012-02-16
US20130252310A1 (en) 2013-09-26
US20130157342A1 (en) 2013-06-20
EP1533376A1 (en) 2005-05-25
EP2280068A1 (en) 2011-02-02
JP2010284170A (ja) 2010-12-24
CA2714881C (en) 2012-10-23
ATE463568T1 (de) 2010-04-15
US20080318290A1 (en) 2008-12-25
JPWO2004018672A1 (ja) 2005-12-08
CA2484871C (en) 2010-11-30
KR100741650B1 (ko) 2007-07-24

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