DK152744C - Fremgangsmaade til fremstilling af et farmaceutisk peroralt polydepotpraeparat - Google Patents

Fremgangsmaade til fremstilling af et farmaceutisk peroralt polydepotpraeparat

Info

Publication number
DK152744C
DK152744C DK365282A DK365282A DK152744C DK 152744 C DK152744 C DK 152744C DK 365282 A DK365282 A DK 365282A DK 365282 A DK365282 A DK 365282A DK 152744 C DK152744 C DK 152744C
Authority
DK
Denmark
Prior art keywords
units
preparation
controlled release
pharmaceutical
active substance
Prior art date
Application number
DK365282A
Other languages
English (en)
Other versions
DK152744B (da
DK365282A (da
Inventor
Stig Roswall
Lene Birgitte Thorhus
Original Assignee
Benzon As Alfred
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Benzon As Alfred filed Critical Benzon As Alfred
Priority to DK365282A priority Critical patent/DK152744C/da
Priority to DE8383304583T priority patent/DE3382341D1/de
Priority to DE198383304583T priority patent/DE106443T1/de
Priority to EP83304583A priority patent/EP0106443B1/en
Priority to AT83304583T priority patent/ATE65181T1/de
Priority to AU17854/83A priority patent/AU1785483A/en
Priority to FI832909A priority patent/FI832909A/fi
Priority to CA000434484A priority patent/CA1218305A/en
Priority to NO832895A priority patent/NO832895L/no
Priority to JP58148684A priority patent/JPS5962521A/ja
Priority to US06/523,635 priority patent/US4574080A/en
Publication of DK365282A publication Critical patent/DK365282A/da
Publication of DK152744B publication Critical patent/DK152744B/da
Application granted granted Critical
Publication of DK152744C publication Critical patent/DK152744C/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK365282A 1982-08-13 1982-08-13 Fremgangsmaade til fremstilling af et farmaceutisk peroralt polydepotpraeparat DK152744C (da)

Priority Applications (11)

Application Number Priority Date Filing Date Title
DK365282A DK152744C (da) 1982-08-13 1982-08-13 Fremgangsmaade til fremstilling af et farmaceutisk peroralt polydepotpraeparat
DE8383304583T DE3382341D1 (de) 1982-08-13 1983-08-09 Pharmazeutische orale formulierung mit mehrfachen einheiten, mit kontrollierter freisetzung.
DE198383304583T DE106443T1 (de) 1982-08-13 1983-08-09 Pharmazeutische orale formulierung mit mehrfachen einheiten, mit kontrollierter freisetzung.
EP83304583A EP0106443B1 (en) 1982-08-13 1983-08-09 Pharmaceutical oral-controlled release multiple-units formulation
AT83304583T ATE65181T1 (de) 1982-08-13 1983-08-09 Pharmazeutische orale formulierung mit mehrfachen einheiten, mit kontrollierter freisetzung.
AU17854/83A AU1785483A (en) 1982-08-13 1983-08-10 Slow release and fast release tablet formulation comprising two active ingredients
FI832909A FI832909A (fi) 1982-08-13 1983-08-12 Farmaceutisk kombinationspreparat och foerfarande foer framstaellning daerav
CA000434484A CA1218305A (en) 1982-08-13 1983-08-12 Combination formulation
NO832895A NO832895L (no) 1982-08-13 1983-08-12 Fremgangsmaate for fremstilling av et farmasoeytisk preparat med regulert frigivning av aktiv substans
JP58148684A JPS5962521A (ja) 1982-08-13 1983-08-13 医薬用の経口放出調整複合単位製剤とその製法
US06/523,635 US4574080A (en) 1982-08-13 1983-08-15 Combination formulation

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK365282A DK152744C (da) 1982-08-13 1982-08-13 Fremgangsmaade til fremstilling af et farmaceutisk peroralt polydepotpraeparat
DK365282 1982-08-13

Publications (3)

Publication Number Publication Date
DK365282A DK365282A (da) 1984-02-14
DK152744B DK152744B (da) 1988-05-09
DK152744C true DK152744C (da) 1988-10-31

Family

ID=8125282

Family Applications (1)

Application Number Title Priority Date Filing Date
DK365282A DK152744C (da) 1982-08-13 1982-08-13 Fremgangsmaade til fremstilling af et farmaceutisk peroralt polydepotpraeparat

Country Status (10)

Country Link
US (1) US4574080A (da)
EP (1) EP0106443B1 (da)
JP (1) JPS5962521A (da)
AT (1) ATE65181T1 (da)
AU (1) AU1785483A (da)
CA (1) CA1218305A (da)
DE (2) DE3382341D1 (da)
DK (1) DK152744C (da)
FI (1) FI832909A (da)
NO (1) NO832895L (da)

Families Citing this family (57)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2470599A1 (fr) * 1979-12-07 1981-06-12 Panoz Donald Perfectionnements apportes aux procedes de preparation de formes galeniques a action retard et a liberation programmee et formes galeniques de medicaments ainsi obtenus
DE3305935C2 (de) * 1983-02-21 1985-05-30 Medice Chem.-Pharm. Fabrik Pütter GmbH & Co KG, 5860 Iserlohn Kaliumneutrales Saluretikum mit antihypertensiver Wirkung
DE3586600T2 (de) * 1984-02-10 1993-02-18 Benzon Pharma As Dosierungsform eine vielzahl mit einer diffusionshuelle ueberzogener einheiten enthaltend.
NL8401362A (nl) * 1984-04-27 1985-11-18 Tno Werkwijze voor het met een polymeer omhullen van deeltjesvormige materialen teneinde de gereguleerde afgifte van deze materialen aan de omgeving mogelijk te maken alsmede aldus verkregen omhuld deeltjesvormig materiaal.
JPS618A (ja) * 1984-06-09 1986-01-06 Sawai Seiyaku Kk ニフエジピン含有製剤
DE3431861A1 (de) * 1984-08-30 1986-03-13 Troponwerke GmbH & Co KG, 5000 Köln Pellet-zubereitung
DE3500103A1 (de) * 1985-01-04 1986-07-10 R.P. Scherer GmbH, 6930 Eberbach Pharmazeutische zubereitung mit einem in wasser und verdauungssaeften schwer loeslichen wirkstoff
US5229132A (en) * 1985-02-22 1993-07-20 Grimberg Georges Serge Non-absorbable gastrointestinal medicament provided for treating the two levels of the digestive tract at the same time
NL8500724A (nl) * 1985-03-13 1986-10-01 Univ Groningen Inrichtingen voor geregelde afgifte van werkzame stoffen, alsmede werkwijze ter vervaardiging daarvan.
GB8507779D0 (en) * 1985-03-26 1985-05-01 Fujisawa Pharmaceutical Co Drug carrier
GB8521494D0 (en) * 1985-08-29 1985-10-02 Zyma Sa Controlled release tablet
US5624683A (en) * 1986-08-06 1997-04-29 Eisai Co., Ltd. Sustained-release multi-granule tablet
US4822619A (en) * 1987-02-18 1989-04-18 Ionor, Inc. Controlled release pharmaceutical preparation containing a gastrointestinal irritant drug
DE3814532A1 (de) * 1988-04-29 1989-11-09 Bayer Ag Dhp-retard-zubereitung
DE3822095A1 (de) * 1988-06-30 1990-01-04 Klinge Co Chem Pharm Fab Neue arzneimittelformulierung sowie verfahren zu deren herstellung
US5612059A (en) * 1988-08-30 1997-03-18 Pfizer Inc. Use of asymmetric membranes in delivery devices
DE3941703C2 (de) * 1989-12-18 2002-11-07 Sanol Arznei Schwarz Gmbh Bumetanid enthaltende pharmazeutische Zubereitung
JPH0794379B2 (ja) * 1990-08-07 1995-10-11 ファイザー・インコーポレーテッド 放出製剤における界面重合膜の使用方法
US5252337A (en) * 1991-06-25 1993-10-12 Eurand America, Inc. Controlled release calcium channel blocker microcapsules
KR100221695B1 (ko) * 1991-08-12 1999-09-15 그린 마틴, 브라이언 쥐 테슬리 약학적 구상 제형
GB9117361D0 (en) * 1991-08-12 1991-09-25 Euro Celtique Sa Oral dosage form
JP2835796B2 (ja) * 1992-02-06 1998-12-14 メルク・ジヤパン株式会社 新規な薄片状顔料
ES2143481T3 (es) * 1992-05-29 2000-05-16 Nikken Chemicals Co Ltd Comprimido de valproato de sodio de liberacion lenta.
US5422122A (en) * 1992-08-04 1995-06-06 Eurand America, Incorporated Controlled release potassium chloride tablet
US5397574A (en) * 1993-10-04 1995-03-14 Andrx Pharmaceuticals, Inc. Controlled release potassium dosage form
US6149953A (en) * 1993-11-08 2000-11-21 Delta Food Group, Inc. Seeded microcapsules
BE1009257A3 (nl) * 1995-03-21 1997-01-07 Universiteit Gent Lab Voor Far Farmaceutische matrix.
US5674529A (en) * 1995-06-06 1997-10-07 Church & Dwight Co., Inc. Alkalinizing potassium salt controlled release preparations
US5773031A (en) * 1996-02-27 1998-06-30 L. Perrigo Company Acetaminophen sustained-release formulation
WO1998041210A1 (fr) * 1997-03-14 1998-09-24 Toray Industries, Inc. Preparation de derive de prostaglandine i a liberation prolongee
FR2766089B1 (fr) * 1997-07-21 2000-06-02 Prographarm Lab Comprime multiparticulaire perfectionne a delitement rapide
US20020054911A1 (en) * 2000-05-11 2002-05-09 Boehringer Mannheim Pharmaceutical Corporation-Sm Ithkline Beckman Corporation, Limited Partnershi Novel oral dosage form for carvedilol
JPH11269064A (ja) * 1998-03-20 1999-10-05 Kowa Co 胃・十二指腸付着性医薬組成物
SE9803240D0 (sv) * 1998-09-24 1998-09-24 Diabact Ab A pharmaceutical composition having a rapid action
DE19921549A1 (de) * 1999-05-11 2000-11-16 Merck Patent Gmbh Mahlhilfsmittel für die Röntgenfluoreszenzanalyse
US6428809B1 (en) * 1999-08-18 2002-08-06 Microdose Technologies, Inc. Metering and packaging of controlled release medication
SE9903236D0 (sv) * 1999-09-10 1999-09-10 Astra Ab Method to obtain microparticles
US20060159756A1 (en) * 1999-09-10 2006-07-20 Brita Sjoblom Method to obtain microparticles containing an H+,K+-ATP-ASE inhibitor
AU2001257359A1 (en) 2000-04-27 2001-11-07 Verion Inc. Zero order release and temperature-controlled microcapsules and process for the preparation thereof
US6958161B2 (en) 2002-04-12 2005-10-25 F H Faulding & Co Limited Modified release coated drug preparation
EP1545461A4 (en) * 2002-09-09 2011-06-22 Endo Pharmaceuticals Inc COMBINED ANALGESIC COMPOSITION WITH IMMEDIATE AND PROLONGED RELEASE
US20080051411A1 (en) * 2002-12-17 2008-02-28 Cink Russell D Salts of Fenofibric Acid and Pharmaceutical Formulations Thereof
CN100473378C (zh) * 2002-12-17 2009-04-01 阿伯特有限及两合公司 包含非诺贝酸、其生理可接受的盐或衍生物的制剂
US7259186B2 (en) * 2002-12-17 2007-08-21 Abbott Laboratories Salts of fenofibric acid and pharmaceutical formulations thereof
US7632521B2 (en) * 2003-07-15 2009-12-15 Eurand, Inc. Controlled release potassium chloride tablets
FR2861990B1 (fr) * 2003-11-10 2006-02-10 Nouveaux Produits Pharma Comprimes faiblement doses a reseau de polymeres
ES2308065T3 (es) * 2004-04-30 2008-12-01 Topotarget Germany Ag Formulacion que comprende un inhibidor de histona desacetilasa, que exhibe una liberacion bifasica.
CN1993111A (zh) * 2004-05-21 2007-07-04 阿库-伯雷克技术公司 含有相对无活性片段的药片
WO2005115380A2 (en) * 2004-05-27 2005-12-08 Dexcel Pharma Technologies Ltd Localized controlled absorption of statins in the gastrointestinal tract for achieving high blood levels of statins
GB0423800D0 (en) * 2004-10-27 2004-12-01 Orexo Ab New pharmaceutical formulations
US20080152714A1 (en) * 2005-04-08 2008-06-26 Yi Gao Pharmaceutical Formulations
BRPI0520797B8 (pt) * 2005-11-18 2021-05-25 Accu Break Tech Inc forma de dosagem farmacêutica comprimida em bicamadas
WO2008006534A2 (en) * 2006-07-11 2008-01-17 Lek Pharmaceuticals D.D. Multiple unit tablets
US8241661B1 (en) * 2011-06-24 2012-08-14 Fuisz Richard C Biocompatible film with variable cross-sectional properties
DK2674153T3 (en) * 2012-06-14 2016-12-05 Ratiopharm Gmbh Oral dosage form for the immediate release of bendroflumethiazide and controlled release of a second active agent
CA2936748C (en) 2014-10-31 2017-08-08 Purdue Pharma Methods and compositions particularly for treatment of attention deficit disorder
US10722473B2 (en) 2018-11-19 2020-07-28 Purdue Pharma L.P. Methods and compositions particularly for treatment of attention deficit disorder

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3538214A (en) * 1969-04-22 1970-11-03 Merck & Co Inc Controlled release medicinal tablets
DE2031871C3 (de) * 1970-06-27 1974-06-27 Roehm Gmbh, 6100 Darmstadt Überzugsmasse für Arzneiformen
US3873346A (en) * 1970-12-23 1975-03-25 Us Interior Process of forming self-destructing pesticidal formulations
US3909444A (en) * 1971-08-05 1975-09-30 Ncr Co Microcapsule
GB1468172A (en) * 1973-03-28 1977-03-23 Benzon As Alfred Oral drug preparations
GB1576376A (en) * 1977-03-30 1980-10-08 Benzon As Alfred Multiple-unit drug dose
FR2397840B1 (da) * 1977-07-22 1981-03-20 Cherqui Jean
DE2849494A1 (de) * 1978-11-15 1980-05-29 Voss Gunter M Verfahren zur herstellung von arzneimittel-formlingen
US4173626A (en) * 1978-12-11 1979-11-06 Merck & Co., Inc. Sustained release indomethacin
US4221778A (en) * 1979-01-08 1980-09-09 Pennwalt Corporation Prolonged release pharmaceutical preparations
US4316884A (en) * 1979-01-25 1982-02-23 Adria Laboratories, Inc. Sustained release pharmaceutical formulation
US4353887A (en) * 1979-08-16 1982-10-12 Ciba-Geigy Corporation Divisible tablet having controlled and delayed release of the active substance
JPS5911563B2 (ja) * 1980-02-27 1984-03-16 日本原子力研究所 多層構造の徐放性複合体を製造する方法
JPS56152739A (en) * 1980-04-25 1981-11-26 Tanabe Seiyaku Co Ltd Production of microcapsule
US4259315A (en) * 1980-06-13 1981-03-31 A. H. Robins Company, Inc. Controlled release potassium dosage form

Also Published As

Publication number Publication date
ATE65181T1 (de) 1991-08-15
DE106443T1 (de) 1984-09-13
FI832909A (fi) 1984-02-14
DK152744B (da) 1988-05-09
JPS6238323B2 (da) 1987-08-17
CA1218305A (en) 1987-02-24
US4574080A (en) 1986-03-04
DK365282A (da) 1984-02-14
EP0106443B1 (en) 1991-07-17
EP0106443A2 (en) 1984-04-25
DE3382341D1 (de) 1991-08-22
FI832909A0 (fi) 1983-08-12
EP0106443A3 (en) 1985-11-27
AU1785483A (en) 1984-02-16
JPS5962521A (ja) 1984-04-10
NO832895L (no) 1984-02-14

Similar Documents

Publication Publication Date Title
DK152744C (da) Fremgangsmaade til fremstilling af et farmaceutisk peroralt polydepotpraeparat
EE9700176A (et) Kuivpulbriinhalaatorites kasutatav pulber, selle valmistamismeetod, selles kasutatavad osakesed ja meetod nende valmistamiseks ning pulbri lisandi kasutamine
DK28480A (da) Fremgangsmaade til fremstilling af tabletter med forsinket frigivelse af det aktive middel i hvilke tabletter frigivelseshastigheden for det aktive middel er fastlagt i forvejen
ES526783A0 (es) Procedimiento de obtencion de un polvo polimerico para el revestimiento enterico de formas de dosificacion farmaceuticas
ATE47520T1 (de) Darmloesliche ueberzugsmasse fuer pharmazeutische verabreichungsformen.
DE3771091D1 (de) Formulierung mit langsamer freisetzung.
IT1200424B (it) Fosforo rosso stabilizzato per uso come ritardante di fiamma,particolarmente per composizioni a base di polimeri
ES8303088A1 (es) Procedimiento para la obtencion de una forma retardada de medicamento granulado.
IL53594A (en) Biological cells comprising pharmaceutically active substances and additives controlling their release from the cells,their preparation and pharmaceutical compositions containing them
ES8402720A1 (es) Procedimiento para la obtencion de una composicion a base de estireno para revestir alimentos y medicamentos.
NO884530D0 (no) Plaster med aktive stoffer for styrt avgivelse av aktive stoffer til huden, anvendelse saavel som fremgangsmaate for styrt avgivelse av aktive stoffer til huden.
DK409177A (da) Overtraek til sikring af kontrolleret afgivelse af virksomme bestanddele af biologisk aktive praeparater samt fremgangsmaade til fremstilling af biologisk aktive praeparater med saadant overtraek
ES531434A0 (es) Procedimiento para el recubrimiento de sustratos mediante aplicacion del recubrimiento en forma de pelicula y posterior ahornado.
DE3678643D1 (de) Partikel mit konstanter wirkstofffreisetzung.
DE3678641D1 (de) Partikel mit konstanter wirkstofffreisetzung.
PT74654A (pt) Process for the preparation of compositions in powder form containing pesticides and suitable for treatment of house hold furnishing
DK275582A (da) Depotorgan til frigivelse af biologisk aktive stoffer til fordoejelseskanalen samt fremgangsmaade til anvendelse heraf
JPS52125630A (en) Antiperkinson drugs containing l-threo-3,4-dihydroxyphenylserine
JPS57142913A (en) Donor of physiologically active substance
JPS6485911A (en) Plaster
JPS54126722A (en) Slow release antibiotic tablet
JPS6426515A (en) Composition with controlled release speed and manufacture
JPS547888A (en) Implanted capacitance device
DK133981A (da) Fremgangsmaade til fremstilling af et koncentrat indeholdende en veldefineret,men lille maengde aktive stoffer
JPS5581138A (en) Manufacturing of feed roller

Legal Events

Date Code Title Description
PBP Patent lapsed