DK150986A - Hydroxamater med lipoxygenase-inhiberende virkning og terapeutiske midler indeholdende saadanne forbindelser - Google Patents

Hydroxamater med lipoxygenase-inhiberende virkning og terapeutiske midler indeholdende saadanne forbindelser Download PDF

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Publication number
DK150986A
DK150986A DK150986A DK150986A DK150986A DK 150986 A DK150986 A DK 150986A DK 150986 A DK150986 A DK 150986A DK 150986 A DK150986 A DK 150986A DK 150986 A DK150986 A DK 150986A
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DK
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Prior art keywords
hydroxamates
lipoxygenase
compounds
therapeutic agents
agents containing
Prior art date
Application number
DK150986A
Other languages
English (en)
Other versions
DK150986D0 (da
Inventor
Fu-Chih Huang
Original Assignee
Usv Pharma Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Usv Pharma Corp filed Critical Usv Pharma Corp
Publication of DK150986D0 publication Critical patent/DK150986D0/da
Publication of DK150986A publication Critical patent/DK150986A/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D215/14—Radicals substituted by oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK150986A 1985-04-03 1986-04-03 Hydroxamater med lipoxygenase-inhiberende virkning og terapeutiske midler indeholdende saadanne forbindelser DK150986A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US71919985A 1985-04-03 1985-04-03
US06/830,798 US4792560A (en) 1985-04-03 1986-02-19 Quinoline hydroxamates and their use as modulators of arachidonic acid metabolic pathways

Publications (2)

Publication Number Publication Date
DK150986D0 DK150986D0 (da) 1986-04-03
DK150986A true DK150986A (da) 1986-10-04

Family

ID=27110043

Family Applications (1)

Application Number Title Priority Date Filing Date
DK150986A DK150986A (da) 1985-04-03 1986-04-03 Hydroxamater med lipoxygenase-inhiberende virkning og terapeutiske midler indeholdende saadanne forbindelser

Country Status (7)

Country Link
US (1) US4792560A (da)
EP (1) EP0196674A3 (da)
AU (1) AU5568186A (da)
DK (1) DK150986A (da)
ES (1) ES8708127A1 (da)
FI (1) FI861444A (da)
NO (1) NO861306L (da)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4607053A (en) * 1984-05-17 1986-08-19 E. R. Squibb & Sons, Inc. Arylhydroxamates useful as antiallergy agents
GB8531839D0 (en) * 1985-12-30 1986-02-05 Wellcome Found Aryl derivatives
IE59397B1 (en) * 1985-03-16 1994-02-23 Wellcome Found New aryl derivatives
US4731382A (en) * 1986-12-29 1988-03-15 Bristol-Myers Company Lipoxygenase inhibitory phenylalkanohydroxamic acids
US4861798A (en) * 1986-12-29 1989-08-29 Bristol-Myers Company Lipoxygenase inhibitory compounds
US5155110A (en) * 1987-10-27 1992-10-13 Warner-Lambert Company Fenamic acid hydroxamate derivatives having cyclooxygenase and 5-lipoxygenase inhibition
US5112868A (en) * 1988-05-19 1992-05-12 Warner-Lambert Company Hydroxamate derivatives of selected nonsteroidal antiinflammatory acyl residues having cyclooxygenase and 5-lipoxygenase inhibition
US4943587A (en) * 1988-05-19 1990-07-24 Warner-Lambert Company Hydroxamate derivatives of selected nonsteroidal antiinflammatory acyl residues and their use for cyclooxygenase and 5-lipoxygenase inhibition
IL92915A0 (en) * 1989-01-05 1990-09-17 Ciba Geigy Ag Certain pyrrolylphenyl-substituted hydroxamic acid derivatives
US5096919A (en) * 1989-01-05 1992-03-17 Ciba-Geigy Corporation Pyrrolylphenyl-substituted hydroxamic acid derivatives
US4960787A (en) * 1989-02-06 1990-10-02 Ciba-Geigy Corporation Certain pyrrolyl-substituted hydroxamic acid derivatives
US5112846A (en) * 1989-05-26 1992-05-12 Warner-Lambert Company N-hydroxyamide, N-hydroxythioamide, hydroxyurea, and N-hydroxythiourea derivatives of selected nsaids as antiinflammatory agents
US5075330A (en) * 1989-05-26 1991-12-24 Warner-Lambert Co. N-hydroxyamide, N-hydroxythioamide, N-hydroxyurea, and N-hydroxythiourea derivatives of selected NSAIDS as antiinflammatory agents
US4981865A (en) * 1989-05-26 1991-01-01 Warner-Lambert Co. N-hydroxyamide, N-hydroxythioamide, hydroxyurea, and N-hydroxythiourea derivatives of selected nsaids as antiinflammatory agents
US5155130A (en) * 1989-08-11 1992-10-13 Ciba-Geigy Corporation Certain benzopyran and benzothiopyran derivatives
US5229516A (en) * 1989-10-27 1993-07-20 American Home Products Corporation Substituted indole-, indene-, pyranoindole- and tetrahydrocarbazole-alkanoic acid derivatives as inhibitors of PLA2 and lipoxygenase
US5017604A (en) * 1990-04-11 1991-05-21 Warner-Lambert Company Novel fenamic acid methyl hydroxamate derivatives having cyclooxygenase and 5-lipoxygenase inhibition
US5120758A (en) * 1991-02-08 1992-06-09 Ciba-Geigy Corporation Certain benzodioxole, benzodioxane and benzodioxepin derivatives useful as 5-lipoxygenase inhibitors
US5140047A (en) * 1991-05-03 1992-08-18 Smithkline Beecham Corporation Lipoxygenase inhibitors
US5260316A (en) * 1991-07-30 1993-11-09 Ciba-Geigy Corporation Isoquinolyl substituted hydroxylamine derivatives
US5350761A (en) * 1991-07-30 1994-09-27 Ciba-Geigy Corporation Indolyl substituted hydroxylamine derivatives
US5334600A (en) * 1991-07-30 1994-08-02 Ciba-Geigy Corporation Isoquinolyl substituted hydroxylamine derivatives
US5358955A (en) * 1992-10-30 1994-10-25 Abbott Laboratories Aryl and heteroarylmethoxyphenyl inhibitors of leukotriene biosynthesis
IT1283637B1 (it) * 1996-05-14 1998-04-23 Italfarmaco Spa Composti ad attivita' antinfiammatoria ed immunosoppressiva
CA2391952C (en) 1999-11-23 2012-01-31 Methylgene Inc. Inhibitors of histone deacetylase
JP2004527530A (ja) * 2001-04-05 2004-09-09 スミスクライン・ビーチャム・コーポレイション ペプチドデホルミラーゼ阻害物質
US8796330B2 (en) * 2006-12-19 2014-08-05 Methylgene Inc. Inhibitors of histone deacetylase and prodrugs thereof
GB0821010D0 (en) * 2008-11-17 2008-12-24 Univ Warwick Plant development control composition
US9593136B2 (en) * 2011-07-01 2017-03-14 The George Washington University Compounds for inhibiting 1-deoxy-D-xylulose-5-phosphate reductoisomerase
US9636298B2 (en) 2014-01-17 2017-05-02 Methylgene Inc. Prodrugs of compounds that enhance antifungal activity and compositions of said prodrugs

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL6406688A (da) * 1964-06-05 1965-12-06
BE689347A (da) * 1965-12-09 1967-04-14 Madan Ag
US3481970A (en) * 1967-05-08 1969-12-02 Standard Oil Co Process for preparation of beta-chloromethacrylonitrile
SE363818B (da) * 1968-08-15 1974-02-04 Lilly Co Eli
GB1396726A (en) * 1972-06-15 1975-06-04 Boots Co Ltd Phenylalkanoic acids
IT1046338B (it) * 1974-12-06 1980-06-30 Manetti & Roberts Italo Brit Procedimento per preparare aoido 2,4 isoputil fenil propioidros sanico e combusto intermerio beriesso
NL7614113A (nl) * 1976-12-18 1978-06-20 Akzo Nv Hydroxamzuren.

Also Published As

Publication number Publication date
FI861444A0 (fi) 1986-04-03
AU5568186A (en) 1986-10-09
FI861444A (fi) 1986-10-04
EP0196674A3 (en) 1988-06-15
US4792560A (en) 1988-12-20
ES554125A0 (es) 1987-10-16
ES8708127A1 (es) 1987-10-16
EP0196674A2 (en) 1986-10-08
DK150986D0 (da) 1986-04-03
NO861306L (no) 1986-10-06

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment
PBP Patent lapsed