DK147513C - Analogifremgangsmaade til fremstilling af cefuroximestere - Google Patents

Analogifremgangsmaade til fremstilling af cefuroximestere

Info

Publication number
DK147513C
DK147513C DK168778A DK168778A DK147513C DK 147513 C DK147513 C DK 147513C DK 168778 A DK168778 A DK 168778A DK 168778 A DK168778 A DK 168778A DK 147513 C DK147513 C DK 147513C
Authority
DK
Denmark
Prior art keywords
cefuroximesters
manufacture
analogy procedure
analogy
procedure
Prior art date
Application number
DK168778A
Other languages
English (en)
Other versions
DK147513B (da
DK168778A (da
Inventor
Michael Gregson
Original Assignee
Glaxo Lab Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Lab Ltd filed Critical Glaxo Lab Ltd
Publication of DK168778A publication Critical patent/DK168778A/da
Publication of DK147513B publication Critical patent/DK147513B/da
Application granted granted Critical
Publication of DK147513C publication Critical patent/DK147513C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/26—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C68/00—Preparation of esters of carbonic or haloformic acids
    • C07C68/06—Preparation of esters of carbonic or haloformic acids from organic carbonates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C68/00—Preparation of esters of carbonic or haloformic acids
    • C07C68/02—Preparation of esters of carbonic or haloformic acids from phosgene or haloformates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/26—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
    • C07D501/34—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group with the 7-amino radical acylated by carboxylic acids containing hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK168778A 1977-04-19 1978-04-18 Analogifremgangsmaade til fremstilling af cefuroximestere DK147513C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB1620277 1977-04-19
GB16202/77A GB1598568A (en) 1977-04-19 1977-04-19 Esters of(6r,7r)-3-carbamoyloxymethyl-7-((z)-2-(fur-2-yl)-2-methoxyiminoacetamido)-ceph-3-em-4-carboxylic acid

Publications (3)

Publication Number Publication Date
DK168778A DK168778A (da) 1978-10-20
DK147513B DK147513B (da) 1984-09-10
DK147513C true DK147513C (da) 1985-03-18

Family

ID=10073017

Family Applications (1)

Application Number Title Priority Date Filing Date
DK168778A DK147513C (da) 1977-04-19 1978-04-18 Analogifremgangsmaade til fremstilling af cefuroximestere

Country Status (20)

Country Link
JP (1) JPS53132592A (da)
KR (1) KR840000081B1 (da)
AT (1) AT363183B (da)
AU (1) AU521098B2 (da)
BE (1) BE866093A (da)
CA (1) CA1093068A (da)
CH (1) CH639096A5 (da)
DE (1) DE2816873A1 (da)
DK (1) DK147513C (da)
ES (1) ES468895A1 (da)
FR (1) FR2387988A1 (da)
GB (1) GB1598568A (da)
IE (1) IE46726B1 (da)
IL (1) IL54531A (da)
IT (1) IT1104842B (da)
NL (1) NL7804097A (da)
NZ (1) NZ186998A (da)
SE (1) SE433748B (da)
YU (1) YU90978A (da)
ZA (1) ZA782211B (da)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2482587A1 (fr) * 1980-05-14 1981-11-20 Poudres & Explosifs Ste Nale Procede de synthese de chloroformiates a-chlores et nouveaux chloroformiates a-chlores
GR76477B (da) * 1981-03-23 1984-08-10 Kyoto Pharma Ind
FR2532933B1 (fr) * 1982-06-29 1987-11-13 Astra Laekemedel Ab Perfectionnements apportes a la preparation d'antibiotiques
GB2123821B (en) * 1982-06-29 1987-04-23 Astra Laekemedel Ab At-halogeno diethyl carbonates and their use in the preparation of antibiotics
IT1190897B (it) * 1982-06-29 1988-02-24 Opos Biochimica Srl Procedimento per la preparazione dell'estere 1-etossicarbonilossietilico dell'acido 6-(d(-)-alfa aminoalfa fenilacetamido)-penicillanico
IL68992A (en) * 1982-06-29 1991-06-10 Astra Laekemedel Ab Alpha-bromo diethyl carbonate and process for the preparation of ethoxycarbonyloxy esters of penicillanic acids
YU44680B (en) * 1982-07-30 1990-12-31 Glaxo Lab Ltd Process for obtaining very pure amorphous form of cephuroxim axetile
US4606865A (en) * 1982-09-20 1986-08-19 Astra Lakemedel Aktiebolag Methods for the preparation of α-bromodiethylcarbonate
IL67623A (en) * 1983-01-05 1984-09-30 Teva Pharma 1'-ethoxycarbonyloxyethyl ester of valproic acid,its preparation and pharmaceutical compositions containing it
GB8320521D0 (en) * 1983-07-29 1983-09-01 Glaxo Group Ltd Chemical process
FR2551058B1 (fr) * 1983-08-26 1986-09-26 Poudres & Explosifs Ste Nale Procede de preparation de chloroformiates a-chlores
GB8400024D0 (en) * 1984-01-03 1984-02-08 Glaxo Group Ltd Cephalosporin antibiotics
US4612143A (en) * 1984-09-17 1986-09-16 Societe Nationale Des Poudres Et Explosifs Process for the preparation of fluoroformates
US5202454A (en) * 1986-07-11 1993-04-13 Societe Nationale Des Poudres Et Explosifs Process for the manufacture of 1-bromoalkyl hydrocarbyl carbonates
KR100342944B1 (ko) * 1999-11-08 2002-07-02 민경윤 고순도 세프포독심 프록세틸의 제조방법
GB0301938D0 (en) * 2003-01-28 2003-02-26 Biochemie Gmbh Organic compounds

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1453049A (en) * 1973-08-21 1976-10-20 Glaxo Lab Ltd Cephalosporing antibiotics
CA1093549A (en) * 1976-02-16 1981-01-13 Michael Gregson Cephalosporin antibiotics
CA1094545A (en) * 1976-02-16 1981-01-27 Michael Gregson Cephalosporin antibiotics

Also Published As

Publication number Publication date
NL7804097A (nl) 1978-10-23
ZA782211B (en) 1979-04-25
IL54531A (en) 1981-07-31
IL54531A0 (en) 1978-07-31
SE7804400L (sv) 1978-10-20
CH639096A5 (en) 1983-10-31
KR830000246A (ko) 1983-03-30
SE433748B (sv) 1984-06-12
ES468895A1 (es) 1978-12-01
IE780760L (en) 1978-10-19
IT1104842B (it) 1985-10-28
FR2387988A1 (fr) 1978-11-17
IT7848941A0 (it) 1978-04-18
DK147513B (da) 1984-09-10
FR2387988B1 (da) 1982-06-11
CA1093068A (en) 1981-01-06
NZ186998A (en) 1981-05-01
DK168778A (da) 1978-10-20
AU3518778A (en) 1979-10-25
BE866093A (fr) 1978-10-18
AT363183B (de) 1981-07-10
YU90978A (en) 1983-01-21
AU521098B2 (en) 1982-03-18
IE46726B1 (en) 1983-09-07
KR840000081B1 (ko) 1984-02-08
DE2816873A1 (de) 1978-11-02
ATA274878A (de) 1980-12-15
GB1598568A (en) 1981-09-23
JPS53132592A (en) 1978-11-18

Similar Documents

Publication Publication Date Title
DK148280C (da) Analogifremgangsmaade til fremstilling af thienothiazinderivater
DK155367C (da) Analogifremgangsmaade til fremstilling af 2-nitroimidazolderivater
DK149062C (da) Analogifremgangsmaade til fremstilling af cefuroximestere
DK207178A (da) Fremgangsmaade til fremstilling af sojaskraa
DK110778A (da) Fremgangsmaade til fremstilling af 4-acylamino-phenyl-ethanolaminer
DK354678A (da) Fremgangsmaade til fremstilling af propenylaminer
DK306978A (da) Fremgangsmaade til fremstilling af 1-acyl-2-cyanaziridiner
DK569678A (da) Fremgangsmaade til fremstilling af 2alfa-cyano-3-oxosteroider
DK153482C (da) Analogifremgangsmaade til fremstilling af 5-cyano-prostacyklinderivater
DK147513C (da) Analogifremgangsmaade til fremstilling af cefuroximestere
DK484677A (da) Fremgangsmaade til fremstilling af furokumariner
DK154137C (da) Analogifremgangsmaade til fremstilling af meta-sulfonamido-benzamidderivater
DK145701C (da) Fremgangsmaade til fremstilling af ergotalkaloider
DK466878A (da) Fremgangsmaade til fremstilling af 0-methallyloxyphenol
DK237978A (da) Fremgangsmaade til fremstilling af alfafluormethyl-alfa-aminoalkansyrer
DK154949C (da) Fremgangsmaade til fremstilling af trifluormethylphenoler
DK436978A (da) Fremgangsmaade til fremstilling af sarcosinoxidase
DK192778A (da) Fremgangsmaade til fremstilling af bisamidiner
DK577078A (da) Fremgangsmaade til fremstilling af trans-4a-aryloctahydro-1h-2-pyridiner
DK364578A (da) Fremgangsmaade til fremstilling af hydroxyphenylhydantoin
DK73977A (da) Fremgangsmade til fremstilling af d-homosteroider
DK248978A (da) Fremgangsmaade til fremstilling af hydroxy-alfa-aminobenzylpenicillin
DK210778A (da) Fremgangsmaade til fremstilling af stabileserede prostaglan-e-praeparater
DK98478A (da) Fremgangsmaade til fremstilling af antibiotika
DK558378A (da) Fremgangsmaade til fremstilling af alfacyanobensylestere

Legal Events

Date Code Title Description
PBP Patent lapsed
B1 Patent granted (law 1993)
PBP Patent lapsed