DK147405C - 11,11-alkylidensteroider af estran- og 19-nor-pregnanraekken til brug som svangerskabsforebyggende midler - Google Patents

11,11-alkylidensteroider af estran- og 19-nor-pregnanraekken til brug som svangerskabsforebyggende midler

Info

Publication number
DK147405C
DK147405C DK293776A DK293776A DK147405C DK 147405 C DK147405 C DK 147405C DK 293776 A DK293776 A DK 293776A DK 293776 A DK293776 A DK 293776A DK 147405 C DK147405 C DK 147405C
Authority
DK
Denmark
Prior art keywords
pregnancy
estran
series
prevention
alkylidene
Prior art date
Application number
DK293776A
Other languages
English (en)
Other versions
DK147405B (da
DK293776A (da
Inventor
Albertus Joannes Van Den Broek
Original Assignee
Akzo Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from NL7216767A external-priority patent/NL175063C/xx
Priority claimed from NL7315704A external-priority patent/NL7315704A/xx
Application filed by Akzo Nv filed Critical Akzo Nv
Priority to DK293776A priority Critical patent/DK147405C/da
Publication of DK293776A publication Critical patent/DK293776A/da
Publication of DK147405B publication Critical patent/DK147405B/da
Application granted granted Critical
Publication of DK147405C publication Critical patent/DK147405C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0053—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa not substituted in position 16
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051—Estrane derivatives
    • C07J1/0059—Estrane derivatives substituted in position 17 by a keto group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051—Estrane derivatives
    • C07J1/0081—Substituted in position 17 alfa and 17 beta
    • C07J1/0085—Substituted in position 17 alfa and 17 beta the substituent in position 17 alfa being a saturated hydrocarbon group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051—Estrane derivatives
    • C07J1/0081—Substituted in position 17 alfa and 17 beta
    • C07J1/0088—Substituted in position 17 alfa and 17 beta the substituent in position 17 alfa being an unsaturated hydrocarbon group
    • C07J1/0092—Alkenyl derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051—Estrane derivatives
    • C07J1/0081—Substituted in position 17 alfa and 17 beta
    • C07J1/0088—Substituted in position 17 alfa and 17 beta the substituent in position 17 alfa being an unsaturated hydrocarbon group
    • C07J1/0096—Alkynyl derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J11/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J21/005—Ketals
    • C07J21/008—Ketals at position 17
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J33/00—Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J33/005—Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton spiro-condensed
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0007—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa
    • C07J5/0023—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa substituted in position 16
    • C07J5/003—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group including 16-alkylidene substitutes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
    • C07J53/002—Carbocyclic rings fused
    • C07J53/004—3 membered carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
    • C07J7/001—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
    • C07J7/001—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group
    • C07J7/0015—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group not substituted in position 17 alfa
    • C07J7/002—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group not substituted in position 17 alfa not substituted in position 16
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
    • C07J7/001—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group
    • C07J7/004—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa
    • C07J7/0045—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa not substituted in position 16
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
    • C07J7/001—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group
    • C07J7/004—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa
    • C07J7/005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa substituted in position 16
    • C07J7/0055—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/008—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21
    • C07J7/0095—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21 carbon in position 21 is part of carboxylic group

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
DK293776A 1972-12-09 1976-06-30 11,11-alkylidensteroider af estran- og 19-nor-pregnanraekken til brug som svangerskabsforebyggende midler DK147405C (da)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DK293776A DK147405C (da) 1972-12-09 1976-06-30 11,11-alkylidensteroider af estran- og 19-nor-pregnanraekken til brug som svangerskabsforebyggende midler

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
NL7216767 1972-12-09
NL7216767A NL175063C (nl) 1972-12-09 1972-12-09 Werkwijze ter bereiding van 11,11-alkylideensteroiden, werkwijze ter bereiding van farmaceutische preparaten en gevormde farmaceutische preparaten.
NL7315704A NL7315704A (en) 1973-11-15 1973-11-15 11,11-Alkylidene steroids - of the oestrane, pregnane and 19-norpregnane series
NL7315704 1973-11-15
DK666473 1973-12-07
DK666473AA DK135047B (da) 1972-12-09 1973-12-07 Analogifremgangsmåde til fremstilling af 11,11-alkylidensteroider af estran- eller 19-norpregnanrækken.
DK293776A DK147405C (da) 1972-12-09 1976-06-30 11,11-alkylidensteroider af estran- og 19-nor-pregnanraekken til brug som svangerskabsforebyggende midler
DK293776 1976-06-30

Publications (3)

Publication Number Publication Date
DK293776A DK293776A (da) 1976-06-30
DK147405B DK147405B (da) 1984-07-23
DK147405C true DK147405C (da) 1985-02-04

Family

ID=26644839

Family Applications (2)

Application Number Title Priority Date Filing Date
DK666473AA DK135047B (da) 1972-12-09 1973-12-07 Analogifremgangsmåde til fremstilling af 11,11-alkylidensteroider af estran- eller 19-norpregnanrækken.
DK293776A DK147405C (da) 1972-12-09 1976-06-30 11,11-alkylidensteroider af estran- og 19-nor-pregnanraekken til brug som svangerskabsforebyggende midler

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK666473AA DK135047B (da) 1972-12-09 1973-12-07 Analogifremgangsmåde til fremstilling af 11,11-alkylidensteroider af estran- eller 19-norpregnanrækken.

Country Status (14)

Country Link
US (1) US3927046A (da)
JP (1) JPS5933600B2 (da)
CA (1) CA1021318A (da)
CH (1) CH614453A5 (da)
DE (1) DE2361120C2 (da)
DK (2) DK135047B (da)
ES (1) ES421253A1 (da)
FI (1) FI54128C (da)
FR (1) FR2209577B1 (da)
GB (1) GB1455270A (da)
IE (1) IE38617B1 (da)
IL (1) IL43762A (da)
PH (1) PH11191A (da)
SE (1) SE414771B (da)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL188581C (nl) * 1974-07-15 1992-08-03 Akzo Nv Werkwijze voor het bereiden van 11beta-hydroxy-18-alkylestraanverbindingen.
FR2377419A1 (fr) * 1977-01-13 1978-08-11 Roussel Uclaf Nouveaux derives steroides 11b-substitues 1,3,5 (10) trieniques, leur procede de preparation et leur application comme medicament
FR2377418A1 (fr) * 1977-01-13 1978-08-11 Roussel Uclaf Nouveaux derives steroides 4,9-dieniques 11b-substitues, leur procede de preparation et leur application comme medicaments
NL7701384A (nl) * 1977-02-10 1978-08-14 Akzo Nv Werkwijze voor het bereiden van nieuwe steroiden van de oestraanreeks.
DE2913381A1 (de) * 1979-03-30 1980-10-16 Schering Ag 11-methylensteroide, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
DE3042529A1 (de) * 1980-11-07 1982-06-24 Schering Ag, 1000 Berlin Und 4619 Bergkamen 11-methylen- (delta)(pfeil hoch)1(pfeil hoch)(pfeil hoch)5(pfeil hoch) -steroide, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
AU572589B2 (en) * 1983-12-14 1988-05-12 Upjohn Company, The 11(alpha)-difluoromethyl and (e)-and (z)-11-fluoromethylene steroids
US4567000A (en) * 1984-08-31 1986-01-28 The Upjohn Company 11-Difluoromethylene steroids
JPS6161578U (da) * 1984-09-27 1986-04-25
IE58562B1 (en) * 1985-07-24 1993-10-06 Akzo Nv Novel 11-methylene-oestr-15-enes, processes for their preparation, and pharmaceutical compositions
US5236913A (en) * 1985-07-24 1993-08-17 Akzo N.V. 11-methylene-oestr-15-enes, processes for their preparation, and pharmaceutical compositions
US4662065A (en) * 1986-05-22 1987-05-05 Battery Engineering, Inc. Method for dehydrating manganese dioxide
CA2100514C (en) * 1992-07-29 2005-03-29 Johannes A. M. Hamersma 17-spiromethylene steroids
ZA94715B (en) * 1993-02-08 1994-10-24 Akzo Nv Steroids for treating menopausal complaints
DE4330727C2 (de) * 1993-09-10 1998-02-19 Jenapharm Gmbh Steroidzwischenprodukte und Verfahren zu ihrer Herstellung
DE4344462C2 (de) 1993-12-22 1996-02-01 Schering Ag Zusammensetzung für die Empfängnisverhütung
DE4413184A1 (de) * 1994-04-12 1995-10-19 Schering Ag 10,11-C¶3¶-überbrückte Steroide
DE19723390C1 (de) * 1997-06-04 1998-06-10 Jenapharm Gmbh 9alpha-Hydroxy-8alpha-estra-1,3,5(10)-triene und Verfahren zu deren Herstellung
US5952319A (en) * 1997-11-26 1999-09-14 Research Triangle Institute Androgenic steroid compounds and a method of making and using the same
US6054446A (en) * 1997-12-24 2000-04-25 Sri International Anti-estrogenic steroids, and associated pharmaceutical compositions and methods of use
US20030008870A1 (en) * 2001-02-02 2003-01-09 Joel Krasnow Method of using a cyclooxygenase-2 inhibitor and sex steroids as a combination therapy for the treatment and prevention of dysmenorrhea
EP2266590A3 (en) 2002-02-22 2011-04-20 Shire LLC Active agent delivery sytems and methods for protecting and administering active agents
ITMI20021755A1 (it) * 2002-08-02 2002-11-01 Poli Ind Chimica Spa Processo e nuovi intermedi per la preparazione di steroidi ad attivita' progestinica.
HUP0301332A3 (en) * 2003-05-14 2006-04-28 Richter Gedeon Vegyeszet New mono-and bismethylene steroid derivatives and process for their synthesis and pharmaceutical compositions containing them
CN101445542B (zh) * 2008-12-25 2010-12-29 北京市科益丰生物技术发展有限公司 一种去氧孕烯的制备方法
CN102964418B (zh) * 2010-06-25 2015-04-15 华润紫竹药业有限公司 去氧孕烯的制备工艺及其中间体化合物
CN101857624B (zh) * 2010-06-25 2012-12-12 北京紫竹药业有限公司 去氧孕烯的制备工艺及其中间体化合物
CN102532232A (zh) * 2010-12-27 2012-07-04 上海信谊药厂有限公司 去氧孕烯的制备方法
US20130123523A1 (en) * 2011-11-10 2013-05-16 Klaus Nickisch Methods for the preparation of etonogestrel and desogestrel
CN107955052B (zh) 2011-12-23 2024-07-05 晶体制药独资有限公司 炔基化16-取代-17-酮基类固醇的方法
ES2748597T3 (es) 2012-03-15 2020-03-17 Merck Sharp & Dohme Vía de síntesis combinada para etonogestrel y desogestrel
ITMI20121472A1 (it) 2012-09-04 2014-03-05 Ind Chimica Srl Processo per la preparazione di 11-metilen-18-metilestr-4-en-3,17-dione, utile come intermedio per la sintesi di molecole ad attivita' farmacologica
EP3423464B1 (en) 2016-03-03 2021-05-26 Crystal Pharma, S.A.U. Process and new intermediates for the preparation of 11-methylene steroids
CN107082793B (zh) * 2017-06-16 2019-07-05 上海共拓医药化工有限公司 去氧孕烯重要中间体的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB912036A (en) * 1960-06-23 1962-12-05 British Drug Houses Ltd 11-methylene-5ª--steroids
US3325520A (en) * 1965-12-08 1967-06-13 Searle & Co (optionally 17-hydrocarbon-substituted) 11, 13beta-dialkylgon-4-en-3-ones and esters corresponding
US3299108A (en) * 1965-10-18 1967-01-17 Searle & Co 17alpha-alkynyl/alkenyl-13beta-alkyl-11-alkylgona-1, 3, 5 (10)-triene-3, 17beta-diols, ethers and esters thereof and intermediates thereto
US3346602A (en) * 1966-10-12 1967-10-10 Searle & Co 13beta-alkyl-11-alkylgona-1, 3, 5 (10)-trien-17-ones, ethers and esters thereof
US3527778A (en) * 1969-02-27 1970-09-08 Searle & Co 3,17 - bisoxygenated 11betamethyl - 19 - norpregn - 4 - en - 20 - ones and derivatives thereof

Also Published As

Publication number Publication date
IL43762A0 (en) 1974-03-14
DE2361120A1 (de) 1974-06-12
ES421253A1 (es) 1976-07-16
FR2209577A1 (da) 1974-07-05
DK135047B (da) 1977-02-28
DK135047C (da) 1977-07-25
JPS5029548A (da) 1975-03-25
IL43762A (en) 1978-04-30
FR2209577B1 (da) 1977-06-03
JPS5933600B2 (ja) 1984-08-16
FI54128C (fi) 1978-10-10
DK147405B (da) 1984-07-23
SE414771B (sv) 1980-08-18
FI54128B (fi) 1978-06-30
DK293776A (da) 1976-06-30
IE38617L (en) 1974-06-09
PH11191A (en) 1977-10-28
GB1455270A (en) 1976-11-10
CH614453A5 (da) 1979-11-30
DE2361120C2 (de) 1984-01-19
AU6326373A (en) 1975-06-05
US3927046A (en) 1975-12-16
IE38617B1 (en) 1978-04-26
CA1021318A (en) 1977-11-22

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