DK146537C - Analogifremgangsmaade til fremstilling af spiro-quinolon-hydantoinforbindelser eller syreadditionssalte deraf - Google Patents

Analogifremgangsmaade til fremstilling af spiro-quinolon-hydantoinforbindelser eller syreadditionssalte deraf

Info

Publication number
DK146537C
DK146537C DK144780A DK144780A DK146537C DK 146537 C DK146537 C DK 146537C DK 144780 A DK144780 A DK 144780A DK 144780 A DK144780 A DK 144780A DK 146537 C DK146537 C DK 146537C
Authority
DK
Denmark
Prior art keywords
quinolon
spiro
analogue
preparation
acid addition
Prior art date
Application number
DK144780A
Other languages
English (en)
Other versions
DK144780A (da
DK146537B (da
Inventor
Rodney Caughren Schnur
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of DK144780A publication Critical patent/DK144780A/da
Publication of DK146537B publication Critical patent/DK146537B/da
Application granted granted Critical
Publication of DK146537C publication Critical patent/DK146537C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20Oxygen atoms
    • C07D215/22Oxygen atoms attached in position 2 or 4
    • C07D215/227Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/12Ophthalmic agents for cataracts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D455/00Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
    • C07D455/03Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
    • C07D455/04Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing a quinolizine ring system condensed with only one six-membered carbocyclic ring, e.g. julolidine

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK144780A 1979-04-04 1980-04-02 Analogifremgangsmaade til fremstilling af spiro-quinolon-hydantoinforbindelser eller syreadditionssalte deraf DK146537C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2699079 1979-04-04
US06/026,990 US4193996A (en) 1979-04-04 1979-04-04 Spiro-quinolone hydantoins

Publications (3)

Publication Number Publication Date
DK144780A DK144780A (da) 1980-10-05
DK146537B DK146537B (da) 1983-10-31
DK146537C true DK146537C (da) 1984-04-09

Family

ID=21835021

Family Applications (1)

Application Number Title Priority Date Filing Date
DK144780A DK146537C (da) 1979-04-04 1980-04-02 Analogifremgangsmaade til fremstilling af spiro-quinolon-hydantoinforbindelser eller syreadditionssalte deraf

Country Status (7)

Country Link
US (1) US4193996A (da)
EP (1) EP0017477B1 (da)
JP (1) JPS582955B2 (da)
DE (1) DE3060137D1 (da)
DK (1) DK146537C (da)
GR (1) GR67761B (da)
IE (1) IE49659B1 (da)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU532110B2 (en) * 1979-11-13 1983-09-15 Ici Ltd. Spiro(imidazolidine-4,3:-indoline)-2,2:5-trione derivatives
JPS60142984A (ja) * 1983-12-28 1985-07-29 Kyorin Pharmaceut Co Ltd 新規なスピロピロリジン−2,5−ジオン誘導体およびその製造法
US4656169A (en) * 1984-08-14 1987-04-07 Pfizer Inc. Tetracyclic spiro-hydantoin aldose reductase inhibitors and compositions
JP4939069B2 (ja) * 2006-01-31 2012-05-23 株式会社Tjmデザイン 墨壷

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3821383A (en) * 1972-07-10 1974-06-28 Ayerst Mckenna & Harrison Compositions for and a method of treating diabetic complications
US4117230A (en) * 1976-10-18 1978-09-26 Pfizer Inc. Hydantoin derivatives as therapeutic agents

Also Published As

Publication number Publication date
GR67761B (da) 1981-09-22
DK144780A (da) 1980-10-05
JPS55147283A (en) 1980-11-17
US4193996A (en) 1980-03-18
DK146537B (da) 1983-10-31
JPS582955B2 (ja) 1983-01-19
EP0017477A1 (en) 1980-10-15
DE3060137D1 (en) 1982-02-25
IE49659B1 (en) 1985-11-13
IE800672L (en) 1980-10-04
EP0017477B1 (en) 1982-01-06

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