DK1463836T3 - Vektormedieret organeltransfektion - Google Patents

Vektormedieret organeltransfektion

Info

Publication number
DK1463836T3
DK1463836T3 DK02797288.4T DK02797288T DK1463836T3 DK 1463836 T3 DK1463836 T3 DK 1463836T3 DK 02797288 T DK02797288 T DK 02797288T DK 1463836 T3 DK1463836 T3 DK 1463836T3
Authority
DK
Denmark
Prior art keywords
organelle
vector
mediated
viral
receptor
Prior art date
Application number
DK02797288.4T
Other languages
English (en)
Inventor
Shaharyar M Khan
Original Assignee
Univ Virginia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Virginia filed Critical Univ Virginia
Application granted granted Critical
Publication of DK1463836T3 publication Critical patent/DK1463836T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/04Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/44Oxidoreductases (1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8201Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation
    • C12N15/8214Plastid transformation
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86Viral vectors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2795/00Bacteriophages
    • C12N2795/00011Details
    • C12N2795/10011Details dsDNA Bacteriophages
    • C12N2795/10311Siphoviridae
    • C12N2795/10341Use of virus, viral particle or viral elements as a vector
    • C12N2795/10343Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2800/00Nucleic acids vectors
    • C12N2800/10Plasmid DNA
    • C12N2800/108Plasmid DNA episomal vectors
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2810/00Vectors comprising a targeting moiety
    • C12N2810/50Vectors comprising as targeting moiety peptide derived from defined protein
    • C12N2810/65Vectors comprising as targeting moiety peptide derived from defined protein from plants
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2810/00Vectors comprising a targeting moiety
    • C12N2810/50Vectors comprising as targeting moiety peptide derived from defined protein
    • C12N2810/80Vectors comprising as targeting moiety peptide derived from defined protein from vertebrates

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Virology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Complex Calculations (AREA)
  • Image Generation (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK02797288.4T 2001-12-13 2002-12-12 Vektormedieret organeltransfektion DK1463836T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US34033801P 2001-12-13 2001-12-13
PCT/US2002/039745 WO2003052067A2 (en) 2001-12-13 2002-12-12 Vector mediated organelle transfection

Publications (1)

Publication Number Publication Date
DK1463836T3 true DK1463836T3 (da) 2010-01-18

Family

ID=23332914

Family Applications (1)

Application Number Title Priority Date Filing Date
DK02797288.4T DK1463836T3 (da) 2001-12-13 2002-12-12 Vektormedieret organeltransfektion

Country Status (8)

Country Link
US (1) US7741112B2 (da)
EP (1) EP1463836B1 (da)
AT (1) ATE443158T1 (da)
AU (1) AU2002361649A1 (da)
DE (1) DE60233756D1 (da)
DK (1) DK1463836T3 (da)
ES (1) ES2333704T3 (da)
WO (1) WO2003052067A2 (da)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2333704T3 (es) 2001-12-13 2010-02-26 University Of Virginia Patent Foundation Transfeccion de organulos mediada por un vector.
WO2005001062A2 (en) * 2003-06-25 2005-01-06 Gencia Corporation Modified vectors for organelle transfection
US20090123468A1 (en) 2003-10-24 2009-05-14 Gencia Corporation Transducible polypeptides for modifying metabolism
US8133733B2 (en) 2003-10-24 2012-03-13 Gencia Corporation Nonviral vectors for delivering polynucleotides to target tissues
AU2004297533B2 (en) 2003-10-24 2010-04-29 Gencia Corporation Methods and compositions for delivering polynucleotides
US8062891B2 (en) 2003-10-24 2011-11-22 Gencia Corporation Nonviral vectors for delivering polynucleotides to plants
DE602005019156D1 (de) 2004-05-26 2010-03-18 Anima Cell Metrology Verfahren zur auswertung von ribonukleotidsequenzen
GB0719367D0 (en) 2007-10-03 2007-11-14 Procarta Biosystems Ltd Transcription factor decoys, compositions and methods
EP2188383B1 (en) 2007-10-09 2017-01-18 Anima Cell Metrology, Inc. Systems and methods for measuring translation activity in viable cells
AU2010299444B2 (en) 2009-09-24 2015-12-10 Anima Cell Metrology, Inc. Systems and methods for measuring translation of target proteins in cells
GB201002413D0 (en) 2010-02-12 2010-03-31 Procarta Biosystems Ltd Nucleic acid complexes
GB201005545D0 (en) 2010-04-01 2010-05-19 Procarta Biosystems Ltd Transcription factor decoys
EA038321B1 (ru) 2014-11-06 2021-08-09 Е.И. Дюпон Де Немур Энд Компани Опосредуемая пептидом доставка направляемой рнк эндонуклеазы в клетки
WO2018129440A1 (en) 2017-01-09 2018-07-12 University Of Massachusetts Complexes for gene deletion and editing

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5855618A (en) * 1996-09-13 1999-01-05 Meadox Medicals, Inc. Polyurethanes grafted with polyethylene oxide chains containing covalently bonded heparin
US5854414A (en) * 1997-03-07 1998-12-29 Incyte Pharmaceuticals, Inc. Human mitochondrial membrane protein
US5831020A (en) * 1997-03-25 1998-11-03 The Research Foundation Of State University Of New York Protein-mediated nuclear import of DNA
US6368821B1 (en) 1997-04-14 2002-04-09 Stratagene Process for infecting eukaryotic cells with a bacterial virus
WO2000023568A2 (en) * 1998-10-06 2000-04-27 Albert Einstein College Of Medicine Of Yeshiva University Methods and compositions for decreasing mitochondrial overproduction of reactive oxygen species in cells
CA2272788A1 (en) * 1999-06-11 2000-12-11 Garching Innovation Gmbh Means and methods for transformation of plant mitochondria
ES2333704T3 (es) 2001-12-13 2010-02-26 University Of Virginia Patent Foundation Transfeccion de organulos mediada por un vector.

Also Published As

Publication number Publication date
WO2003052067A2 (en) 2003-06-26
ES2333704T3 (es) 2010-02-26
US7741112B2 (en) 2010-06-22
US20070011759A1 (en) 2007-01-11
ATE443158T1 (de) 2009-10-15
DE60233756D1 (de) 2009-10-29
EP1463836A4 (en) 2007-09-12
AU2002361649A1 (en) 2003-06-30
EP1463836B1 (en) 2009-09-16
WO2003052067A3 (en) 2003-11-13
EP1463836A2 (en) 2004-10-06
AU2002361649A8 (en) 2003-06-30

Similar Documents

Publication Publication Date Title
DK1463836T3 (da) Vektormedieret organeltransfektion
DK1395669T3 (da) Matriks bindingsregioner og fremgangsmåder til anvendelse af disse
FR10C0025I2 (fr) Protéines de fusion du récepteur de IL-1 utilisées comme antagonistes et méthodes d'utilisation et de fabrication
DE60234824D1 (de) Induzierbares expressionssystem in eukaryotischen zellen
ATE478965T1 (de) Lentivirusvektoren und deren verwendung
CY1118782T1 (el) Επιλογη κυτταρων που εκφραζουν ετερομερη πολυπεπτιδια
HK1093014A1 (en) Microsome vaccine
TW200611910A (en) Interferon-alpha polypeptides and conjugates
CY1114047T1 (el) Νεοι φορεις εκφρασης και χρησεις αυτων
DK1240325T3 (da) IL-17 og IL-17R homologe polypeptider og terapeutisk anvendelse deraf
CA2285667A1 (en) Viral vectors having chimeric envelope proteins containing the igg-binding domain of protein a
BR0212093A (pt) Quimeras de proteìna de envelope viral/receptor e métods de utilização
WO2007051063A3 (en) Gpcr expressing cell lines and antibodies
DE69841015D1 (de) Intrazelluläre herstellung von verkürztem hepatitis c-polypeptid e2
ATE306498T1 (de) Von zellen präsentierte peptide
AU3217100A (en) Methods of use of a novel lysyl oxidase-related protein
DE60144021D1 (de) Für zellzyklusproteine kodierende nukleinsäure und deren verwendung
ATE466874T1 (de) Mit scytovirin der domäne 1 verwandte polypeptide
EP1702071A4 (en) TRANSACTIVATION SYSTEM FOR MAMMALIAN CELLS
ATE532861T1 (de) Expressionsvektor
DK1417222T3 (da) Isolerede polypeptider baseret på den neutraliserende epitop af p17-proteinet fra HIV egnet til vacciner samt neutraliserende anti-p17-antistoffer, der specifikt genkender nævnte neutraliserende epitop
DK1307569T3 (da) Fremstilling af rekombinant protein i en prokaryot værtscelle ved forbedret codonanvendelse
EE05691B1 (et) Ekspressioonivektorid ja nende rakendused
ATE338826T1 (de) Rekombinante virale vektoren zur tetracyclinregulierbaren genexpression
DK1634955T3 (da) Konditionale genvektorer, der er reguleret i cis