DK143028C - Fremgangsmaade til fremstilling af n5-methyltetrahydro-homofolinsyre ud fra homofolinsyre - Google Patents

Fremgangsmaade til fremstilling af n5-methyltetrahydro-homofolinsyre ud fra homofolinsyre

Info

Publication number: DK143028C
Authority: DK; Denmark
Prior art keywords: acid; homopholic; methyltetrahydro; preparing; homofolic
Prior art date: 1972-06-16

Application number

DK334073A

Other languages

English (en)

Other versions

DK143028B (da

Inventor

R L Knott

A Taunton-Rigby

Original Assignee

Us Health

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1972-06-16

Filing date

1973-06-15

Publication date

1981-11-02

1973-06-15 Application filed by Us Health filed Critical Us Health

1981-03-16 Publication of DK143028B publication Critical patent/DK143028B/da

1981-11-02 Application granted granted Critical

1981-11-02 Publication of DK143028C publication Critical patent/DK143028C/da

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
- C07D487/14—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D475/00—Heterocyclic compounds containing pteridine ring systems
- C07D475/02—Heterocyclic compounds containing pteridine ring systems with an oxygen atom directly attached in position 4
- C07D475/04—Heterocyclic compounds containing pteridine ring systems with an oxygen atom directly attached in position 4 with a nitrogen atom directly attached in position 2

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Hematology (AREA)
Oncology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Saccharide Compounds (AREA)

DK334073A 1972-06-16 1973-06-15 Fremgangsmaade til fremstilling af n5-methyltetrahydro-homofolinsyre ud fra homofolinsyre DK143028C (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US263559A US3870719A (en)	1972-06-16	1972-06-16	Synthesis of n-5-methyltetrahydrohomofolic acid and related reduced derivatives of homofolic acid
US26355972		1972-06-16

Publications (2)

Publication Number	Publication Date
DK143028B DK143028B (da)	1981-03-16
DK143028C true DK143028C (da)	1981-11-02

Family

ID=23002269

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK334073A DK143028C (da)	1972-06-16	1973-06-15	Fremgangsmaade til fremstilling af n5-methyltetrahydro-homofolinsyre ud fra homofolinsyre

Country Status (19)

Country	Link
US (2)	US3870719A (da)
JP (1)	JPS5541234B2 (da)
AT (1)	AT329201B (da)
AU (1)	AU476569B2 (da)
BE (1)	BE801006A (da)
CA (1)	CA1004672A (da)
CH (1)	CH582178A5 (da)
CS (1)	CS169842B2 (da)
DE (1)	DE2330984A1 (da)
DK (1)	DK143028C (da)
FR (1)	FR2194708B1 (da)
GB (1)	GB1403850A (da)
HU (1)	HU166235B (da)
NL (1)	NL7307992A (da)
NO (1)	NO139890C (da)
PL (1)	PL89778B1 (da)
RO (1)	RO66639A (da)
SE (1)	SE404367B (da)
YU (1)	YU36958B (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5223500A (en) *	1977-02-22	1993-06-29	Bioresearch S.P.A.	Stable pharmaceutical composition of alkaline or alkaline earth 5-methyl tetrahydrofolate
US5124452A (en) *	1978-07-10	1992-06-23	Bioresearch S.P.A.	Process for producing d,1-5-methyltetrahydrofolic acid and its salts
US4148999A (en) *	1977-08-22	1979-04-10	The Government Of The United States Of America	Preparation and purification of citrovorum factor
US4665176A (en) *	1984-10-23	1987-05-12	Mitsui Toatsu Chemicals, Incorporated	Process for the preparation of 5,6,7,8-tetrahydrofolic acid
EP2289549A3 (en)	1999-10-01	2011-06-15	Immunogen, Inc.	Immunoconjugates for treating cancer

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2737515A (en) *	1951-06-30	1956-03-06	American Cyanamid Co	Salts of substituted tetrahydroformyl pteroyl amino acids
US2790802A (en) *	1954-05-06	1957-04-30	American Cyanamid Co	Substituted tetrahydropteridines and method of preparing the same
US3468886A (en) *	1967-10-23	1969-09-23	Us Health Education & Welfare	Tetrahydrohomofolic acid sulfate and synthesis thereof

1972
- 1972-06-16 US US263559A patent/US3870719A/en not_active Expired - Lifetime
1973
- 1973-06-05 SE SE7307895A patent/SE404367B/xx unknown
- 1973-06-08 NL NL7307992A patent/NL7307992A/xx not_active Application Discontinuation
- 1973-06-08 AU AU56718/73A patent/AU476569B2/en not_active Expired
- 1973-06-12 HU HUHE633A patent/HU166235B/hu unknown
- 1973-06-13 YU YU1580/73A patent/YU36958B/xx unknown
- 1973-06-14 GB GB2840473A patent/GB1403850A/en not_active Expired
- 1973-06-15 BE BE132349A patent/BE801006A/xx not_active IP Right Cessation
- 1973-06-15 AT AT529073A patent/AT329201B/de not_active IP Right Cessation
- 1973-06-15 RO RO7375149A patent/RO66639A/ro unknown
- 1973-06-15 FR FR7321806A patent/FR2194708B1/fr not_active Expired
- 1973-06-15 DK DK334073A patent/DK143028C/da not_active IP Right Cessation
- 1973-06-15 CH CH869773A patent/CH582178A5/xx not_active IP Right Cessation
- 1973-06-15 NO NO2499/73A patent/NO139890C/no unknown
- 1973-06-15 CA CA174,120A patent/CA1004672A/en not_active Expired
- 1973-06-15 CS CS4336A patent/CS169842B2/cs unknown
- 1973-06-16 PL PL1973163402A patent/PL89778B1/pl unknown
- 1973-06-16 JP JP6736473A patent/JPS5541234B2/ja not_active Expired
- 1973-06-18 DE DE2330984A patent/DE2330984A1/de not_active Withdrawn
1974
- 1974-08-16 US US05/498,187 patent/US3983118A/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
DK143028B (da)	1981-03-16
AU476569B2 (en)	1976-09-30
AT329201B (de)	1976-04-26
BE801006A (fr)	1973-10-01
NL7307992A (da)	1973-12-18
ATA529073A (de)	1975-07-15
YU158073A (en)	1982-06-18
HU166235B (da)	1975-02-28
AU5671873A (en)	1974-12-12
CH582178A5 (da)	1976-11-30
NO139890B (no)	1979-02-19
US3983118A (en)	1976-09-28
FR2194708A1 (da)	1974-03-01
YU36958B (en)	1984-08-31
NO139890C (no)	1979-05-30
JPS4949992A (da)	1974-05-15
RO66639A (ro)	1982-05-10
DE2330984A1 (de)	1974-01-03
JPS5541234B2 (da)	1980-10-22
GB1403850A (en)	1975-08-28
CA1004672A (en)	1977-02-01
PL89778B1 (da)	1976-12-31
CS169842B2 (da)	1976-07-29
FR2194708B1 (da)	1978-05-26
US3870719A (en)	1975-03-11
SE404367B (sv)	1978-10-02

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Legal Events

Date	Code	Title	Description
1985-02-04	PBP	Patent lapsed