DK139814B - Analogifremgangsmåde til fremstilling af lokalanæstetisk aktive 2-alkyl-2-(dialkylamino- eller pyrrolidino)-2',6'-acetoxylidider i optisk aktiv eller racemisk form eller farmaceutisk acceptable salte deraf. - Google Patents

Analogifremgangsmåde til fremstilling af lokalanæstetisk aktive 2-alkyl-2-(dialkylamino- eller pyrrolidino)-2',6'-acetoxylidider i optisk aktiv eller racemisk form eller farmaceutisk acceptable salte deraf.

Info

Publication number
DK139814B
DK139814B DK619771AA DK619771A DK139814B DK 139814 B DK139814 B DK 139814B DK 619771A A DK619771A A DK 619771AA DK 619771 A DK619771 A DK 619771A DK 139814 B DK139814 B DK 139814B
Authority
DK
Denmark
Prior art keywords
active
acetoxylidides
pyrrolidino
dialkylamino
alkyl
Prior art date
Application number
DK619771AA
Other languages
Danish (da)
English (en)
Other versions
DK139814C (xx
Inventor
Herbert J F Adams
George H Kronberg
Bertil H Takman
Original Assignee
Astra Pharma Prod
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Pharma Prod filed Critical Astra Pharma Prod
Publication of DK139814B publication Critical patent/DK139814B/da
Application granted granted Critical
Publication of DK139814C publication Critical patent/DK139814C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C53/00—Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen
    • C07C53/38—Acyl halides
    • C07C53/46—Acyl halides containing halogen outside the carbonyl halide group
    • C07C53/50—Acyl halides containing halogen outside the carbonyl halide group of acids containing three or more carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
DK619771AA 1970-12-22 1971-12-17 Analogifremgangsmåde til fremstilling af lokalanæstetisk aktive 2-alkyl-2-(dialkylamino- eller pyrrolidino)-2',6'-acetoxylidider i optisk aktiv eller racemisk form eller farmaceutisk acceptable salte deraf. DK139814B (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10077770A 1970-12-22 1970-12-22
US00164022A US3812147A (en) 1970-12-22 1971-07-19 Acylxylidide local anaesthetics

Publications (2)

Publication Number Publication Date
DK139814B true DK139814B (da) 1979-04-23
DK139814C DK139814C (xx) 1979-10-01

Family

ID=26797539

Family Applications (1)

Application Number Title Priority Date Filing Date
DK619771AA DK139814B (da) 1970-12-22 1971-12-17 Analogifremgangsmåde til fremstilling af lokalanæstetisk aktive 2-alkyl-2-(dialkylamino- eller pyrrolidino)-2',6'-acetoxylidider i optisk aktiv eller racemisk form eller farmaceutisk acceptable salte deraf.

Country Status (23)

Country Link
US (1) US3812147A (xx)
JP (1) JPS5644063B1 (xx)
AR (1) AR193840A1 (xx)
AT (1) AT319205B (xx)
AU (1) AU468489B2 (xx)
BE (1) BE776656A (xx)
BR (1) BR7108466D0 (xx)
CA (1) CA943966A (xx)
DD (1) DD99779A5 (xx)
DE (1) DE2162744C3 (xx)
DK (1) DK139814B (xx)
ES (2) ES398210A1 (xx)
FI (1) FI55027C (xx)
FR (1) FR2118985B1 (xx)
GB (1) GB1369259A (xx)
HU (1) HU163373B (xx)
IE (1) IE35909B1 (xx)
IT (1) IT1066334B (xx)
NL (2) NL172149C (xx)
NO (1) NO135934C (xx)
PL (1) PL83097B1 (xx)
SE (1) SE393374B (xx)
SU (1) SU419023A3 (xx)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4237068A (en) * 1971-07-28 1980-12-02 Astra Pharmaceutical Products, Inc. Primary aminoacylanilides
US3957996A (en) * 1971-12-08 1976-05-18 Astra Pharmaceutical Products, Inc. Pharmaceutical local anesthetic compositions
US3966934A (en) * 1971-12-08 1976-06-29 Astra Pharmaceutical Products, Inc. Synergistic local anesthetic compositions
US3975443A (en) * 1972-06-06 1976-08-17 Allen & Hanburys Limited 1-(3,4-dichlorobenzamidomethyl)-cyclohexyldimethylamine
JPS598269B2 (ja) * 1975-08-22 1984-02-23 萬有製薬株式会社 オメガ − アミノアルカンサンアリ−ルアミドノ セイホウ
EP0062322A1 (en) * 1981-04-03 1982-10-13 The B.F. GOODRICH Company Improved process for synthesis of hindered amine stabilizers for polymeric materials
US4891058A (en) * 1988-07-18 1990-01-02 Ici Americas Inc. 1-alkyl-3-aryl imidazolidine-2,4-diones and herbicidal use
SE8900685D0 (sv) * 1989-02-28 1989-02-28 Astra Ab New compounds
US5153226A (en) * 1989-08-31 1992-10-06 Warner-Lambert Company Acat inhibitors for treating hypocholesterolemia
WO2008063603A2 (en) 2006-11-20 2008-05-29 President And Fellows Of Harvard College Methods, compositions, and kits for treating pain and pruritis
EP3485881B1 (en) 2009-07-10 2024-03-13 President and Fellows of Harvard College Permanently charged sodium and calcium channel blockers as anti-inflammatory agents
JP6833811B2 (ja) 2015-08-03 2021-02-24 プレジデント アンド フェローズ オブ ハーバード カレッジ 荷電イオンチャネル遮断薬及び使用方法
US10828287B2 (en) 2019-03-11 2020-11-10 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
US10780083B1 (en) 2019-03-11 2020-09-22 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
EP3937945A4 (en) 2019-03-11 2023-01-04 Nocion Therapeutics, Inc. CHARGED ION CHANNEL BLOCKERS AND METHODS OF USE
JP2022527438A (ja) 2019-03-11 2022-06-02 ノシオン セラピューティクス，インコーポレイテッド 荷電したイオンチャンネル遮断薬および使用方法
CN113924094A (zh) 2019-03-11 2022-01-11 诺西恩医疗公司 酯取代的离子通道阻滞剂及其使用方法
WO2021091586A1 (en) 2019-11-06 2021-05-14 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
MX2022005335A (es) 2019-11-06 2022-08-17 Nocion Therapeutics Inc Bloqueadores de canales ionicos cargados y metodos de uso.
MX2022011194A (es) 2020-03-11 2022-11-08 Nocion Therapeutics Inc Bloqueadores de canales ionicos cargados y metodos de uso.

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1124837A (en) * 1966-06-03 1968-08-21 Wyeth John & Brother Ltd Substituted anilides

Also Published As

Publication number Publication date
AR193840A1 (es) 1973-05-31
NL172149C (nl) 1983-07-18
DD99779A5 (xx) 1973-08-20
US3812147A (en) 1974-05-21
JPS5644063B1 (xx) 1981-10-16
AU3709971A (en) 1973-06-28
DK139814C (xx) 1979-10-01
PL83097B1 (xx) 1975-12-31
NO135934B (xx) 1977-03-21
NL8204126A (nl) 1983-02-01
SE393374B (sv) 1977-05-09
IE35909L (en) 1972-06-22
DE2162744B2 (de) 1981-07-02
NL172149B (nl) 1983-02-16
CA943966A (en) 1974-03-19
BR7108466D0 (pt) 1973-06-14
NO135934C (xx) 1977-06-29
GB1369259A (en) 1974-10-23
FI55027C (fi) 1979-05-10
AU468489B2 (en) 1976-01-15
FI55027B (fi) 1979-01-31
HU163373B (xx) 1973-08-28
AT319205B (de) 1974-12-10
ES425626A1 (es) 1976-06-16
FR2118985B1 (xx) 1975-12-26
NL7117644A (xx) 1972-06-26
ES398210A1 (es) 1975-03-16
IT1066334B (it) 1985-03-04
IE35909B1 (en) 1976-06-23
SU419023A3 (ru) 1974-03-05
DE2162744A1 (de) 1972-07-06
DE2162744C3 (de) 1982-04-15
BE776656A (fr) 1972-06-14
FR2118985A1 (xx) 1972-08-04

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