DK1378245T3 - Transferrin-bindende-proteiner fra neisseria gonorrhoeae og neisseria meningitidis. Deres anvendelse i en vaccine - Google Patents

Transferrin-bindende-proteiner fra neisseria gonorrhoeae og neisseria meningitidis. Deres anvendelse i en vaccine

Info

Publication number: DK1378245T3
Authority: DK; Denmark
Prior art keywords: neisseria; neisseria gonorrhoeae; iron; regulated; outer membrane
Prior art date: 1990-08-23

Application number

DK02028655T

Other languages

English (en)

Inventor

P Frederick Sparling

Cynthia Nau Cornelissen

Original Assignee

Univ North Carolina

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-08-23

Filing date

1991-08-23

Publication date

2009-10-26

1991-08-23 Application filed by Univ North Carolina filed Critical Univ North Carolina

2009-10-26 Application granted granted Critical

2009-10-26 Publication of DK1378245T3 publication Critical patent/DK1378245T3/da

Links

241000588652 Neisseria gonorrhoeae Species 0.000 title abstract 5
241000588650 Neisseria meningitidis Species 0.000 title abstract 3
102000010912 Transferrin-Binding Proteins Human genes 0.000 title 1
108010062476 Transferrin-Binding Proteins Proteins 0.000 title 1
229960005486 vaccine Drugs 0.000 title 1
XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 abstract 4
101001056675 Klebsiella pneumoniae Ferric aerobactin receptor Proteins 0.000 abstract 2
101710116435 Outer membrane protein Proteins 0.000 abstract 2
229910052742 iron Inorganic materials 0.000 abstract 2
108090000623 proteins and genes Proteins 0.000 abstract 2
102000004169 proteins and genes Human genes 0.000 abstract 2
108020003175 receptors Proteins 0.000 abstract 2
230000001105 regulatory effect Effects 0.000 abstract 2

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/22—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Neisseriaceae (F)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
- C07K16/1203—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
- C07K16/1217—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria from Neisseriaceae (F)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Biophysics (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Gastroenterology & Hepatology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Immunology (AREA)
Toxicology (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Peptides Or Proteins (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

DK02028655T 1990-08-23 1991-08-23 Transferrin-bindende-proteiner fra neisseria gonorrhoeae og neisseria meningitidis. Deres anvendelse i en vaccine DK1378245T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US57218790A	1990-08-23	1990-08-23
PCT/US1991/006026 WO1992003467A1 (en)	1990-08-23	1991-08-23	Transferrin binding proteins from neisseria gonorrhoeae and neisseria meningitidis

Publications (1)

Publication Number	Publication Date
DK1378245T3 true DK1378245T3 (da)	2009-10-26

Family

ID=24286735

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
DK02028655T DK1378245T3 (da)	1990-08-23	1991-08-23	Transferrin-bindende-proteiner fra neisseria gonorrhoeae og neisseria meningitidis. Deres anvendelse i en vaccine
DK91918802T DK0546118T3 (da)	1990-08-23	1991-08-23	Transferrinbindende proteiner fra Neisseria gonorrhoeae og Neisseria meningtidis

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
DK91918802T DK0546118T3 (da)	1990-08-23	1991-08-23	Transferrinbindende proteiner fra Neisseria gonorrhoeae og Neisseria meningtidis

Country Status (10)

Country	Link
US (1)	US7582730B2 (da)
EP (2)	EP0546118B1 (da)
JP (3)	JP3532563B2 (da)
AT (2)	ATE439859T1 (da)
AU (1)	AU8747791A (da)
CA (1)	CA2087958C (da)
DE (2)	DE69133622D1 (da)
DK (2)	DK1378245T3 (da)
ES (2)	ES2210228T3 (da)
WO (1)	WO1992003467A1 (da)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6887482B2 (en)	1990-07-16	2005-05-03	The University Of North Carolina At Chapel Hill	Antigenic iron repressible proteins from N. meningitidis related to the hemolysin family of toxins
US6086896A (en) *	1990-07-16	2000-07-11	Imclone Systems Incorporated	Antigenic iron repressible protein from N. meningitidis related to the hemolysin family of toxins
FR2682114B1 (fr) *	1991-10-03	1996-02-23	Pasteur Merieux Serums Vacc	Vaccin de sous-unite contre les infections a neisseria meningitidis et sous-unites correspondantes a l'etat purifie.
FR2692592B1 (fr)	1992-06-19	1995-03-31	Pasteur Merieux Serums Vacc	Fragments d'ADN codant pour les sous-unités du récepteur de la transferrine de Neisseria meningitidis et procédés les exprimant.
US5439808A (en) *	1993-07-23	1995-08-08	North American Vaccine, Inc.	Method for the high level expression, purification and refolding of the outer membrane group B porin proteins from Neisseria meningitidis
FR2724936A1 (fr) *	1994-09-22	1996-03-29	Pasteur Merieux Serums Vacc	Recepteur lactoferrine d'helicobacter
US5747287A (en) *	1995-04-28	1998-05-05	North American Vaccine, Inc.	Method for the high level expression, purification and refolding of the outer membrane group B porin proteins from Neisseria meningitidis
JPH11502418A (ja) *	1995-10-09	1999-03-02	パストゥールメリユセリュムエヴァサン	ヘリコバクターのラクトフェリン受容体
US6610506B1 (en)	1995-12-01	2003-08-26	University Technologies International, Inc.	Transferrin binding proteins of Pasteurella haemolytica and vaccines containing same
GB9726398D0 (en)	1997-12-12	1998-02-11	Isis Innovation	Polypeptide and coding sequences
ES2304065T3 (es) *	1998-05-01	2008-09-01	Novartis Vaccines And Diagnostics, Inc.	Antigenos y composiciones de neisseria meningitidis.
US6692752B1 (en)	1999-09-08	2004-02-17	Smithkline Beecham Biologicals S.A.	Methods of treating human females susceptible to HSV infection
ES2310776T3 (es) *	1998-10-22	2009-01-16	The University Of Montana	Composiciones de vacuna que comprenden proteinas omp de neisseria gonorrhoeae y de neisseria meningitidis.
US6610306B2 (en)	1998-10-22	2003-08-26	The University Of Montana	OMP85 protein of neisseria meningitidis, compositions containing the same and methods of use thereof
DK1535928T3 (da) *	1998-10-22	2008-10-20	Univ Montana	Vaccinesammensætninger indeholdende Omp85-proteiner af Neisseria gonorrhoeae og Neisseria meningitidis
EP1939215A1 (en)	1998-10-22	2008-07-02	The University of Montana	Omp85 proteins of neisseria gonorrhoeae and neisseria meningitidis, compositions containing same and methods of use thereof
EP1069133A1 (en)	1999-07-13	2001-01-17	Institut National De La Sante Et De La Recherche Medicale (Inserm)	Neisseria meningitidis compounds and anti-infection applications thereof
RU2281956C2 (ru) *	1999-10-29	2006-08-20	Чирон С.Р.Л.	Антигенные пептиды neisseria
JP2006500963A (ja)	2002-08-02	2006-01-12	グラクソスミスクラインバイオロジカルズソシエテアノニム	ワクチン組成物
WO2004039417A2 (en)	2002-11-01	2004-05-13	Glaxosmithkline Biologicals S.A.	Drying process
WO2005032584A2 (en)	2003-10-02	2005-04-14	Glaxosmithkline Biologicals S.A.	Pertussis antigens and use thereof in vaccination
ES2397923T3 (es)	2003-10-02	2013-03-12	Novartis Ag	Vacunas líquidas para múltiples serogrupos meningocócicos
GB0505996D0 (en)	2005-03-23	2005-04-27	Glaxosmithkline Biolog Sa	Fermentation process
ATE450271T1 (de)	2006-06-12	2009-12-15	Glaxosmithkline Biolog Sa	Impfstoff
GB0700562D0 (en)	2007-01-11	2007-02-21	Novartis Vaccines & Diagnostic	Modified Saccharides
JP2013521770A (ja)	2010-03-10	2013-06-13	グラクソスミスクラインバイオロジカルズソシエテアノニム	ワクチン組成物
US20120171120A1 (en)	2010-11-30	2012-07-05	Genentech, Inc.	Low affinity blood brain barrier receptor antibodies and uses therefor

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4681761A (en) *	1985-10-24	1987-07-21	State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University	Major iron-regulated protein of Neisseria gonorrhoeae and its use as vaccine
US5292869A (en) *	1989-04-27	1994-03-08	The Board Of Governors Of The University	Method for isolating and purifying transferrin and lactoferrin receptor proteins from bacteria and the preparation of vaccines containing the same
US5141743A (en)	1989-04-27	1992-08-25	University Technologies International, Inc.	Method for isolating and purifying transferrin and lactoferrin receptor proteins and vaccines containing the same
US5912336A (en)	1990-08-23	1999-06-15	University Of North Carolina At Chapel Hill	Isolated nucleic acid molecules encoding transferrin binding proteins from Neisseria gonorrhoeae and Neisseria meningitidis
FR2692592B1 (fr)	1992-06-19	1995-03-31	Pasteur Merieux Serums Vacc	Fragments d'ADN codant pour les sous-unités du récepteur de la transferrine de Neisseria meningitidis et procédés les exprimant.

1991
- 1991-08-23 AT AT02028655T patent/ATE439859T1/de not_active IP Right Cessation
- 1991-08-23 JP JP51718491A patent/JP3532563B2/ja not_active Expired - Lifetime
- 1991-08-23 AT AT91918802T patent/ATE253114T1/de not_active IP Right Cessation
- 1991-08-23 DK DK02028655T patent/DK1378245T3/da active
- 1991-08-23 EP EP91918802A patent/EP0546118B1/en not_active Expired - Lifetime
- 1991-08-23 DE DE69133622T patent/DE69133622D1/de not_active Expired - Lifetime
- 1991-08-23 CA CA002087958A patent/CA2087958C/en not_active Expired - Lifetime
- 1991-08-23 AU AU87477/91A patent/AU8747791A/en not_active Abandoned
- 1991-08-23 WO PCT/US1991/006026 patent/WO1992003467A1/en active IP Right Grant
- 1991-08-23 ES ES91918802T patent/ES2210228T3/es not_active Expired - Lifetime
- 1991-08-23 EP EP02028655A patent/EP1378245B1/en not_active Expired - Lifetime
- 1991-08-23 DK DK91918802T patent/DK0546118T3/da active
- 1991-08-23 ES ES02028655T patent/ES2329979T3/es not_active Expired - Lifetime
- 1991-08-23 DE DE69133334T patent/DE69133334T2/de not_active Expired - Lifetime
2001
- 2001-09-27 JP JP2001296757A patent/JP2002186489A/ja active Pending
2003
- 2003-05-20 JP JP2003141370A patent/JP2005239548A/ja active Pending
2004
- 2004-08-30 US US10/928,311 patent/US7582730B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
DE69133334D1 (de)	2003-12-04
ATE253114T1 (de)	2003-11-15
EP1378245B1 (en)	2009-08-19
AU8747791A (en)	1992-03-17
ATE439859T1 (de)	2009-09-15
US7582730B2 (en)	2009-09-01
CA2087958C (en)	2007-05-15
DE69133334T2 (de)	2004-05-13
ES2210228T3 (es)	2004-07-01
WO1992003467A1 (en)	1992-03-05
EP1378245A3 (en)	2004-01-14
DE69133622D1 (de)	2009-10-01
JP3532563B2 (ja)	2004-05-31
US20070065453A1 (en)	2007-03-22
CA2087958A1 (en)	1992-02-24
DK0546118T3 (da)	2004-02-16
EP0546118B1 (en)	2003-10-29
EP1378245A2 (en)	2004-01-07
EP0546118A4 (en)	1993-07-14
EP0546118A1 (en)	1993-06-16
ES2329979T3 (es)	2009-12-03
JP2002186489A (ja)	2002-07-02
JP2005239548A (ja)	2005-09-08
JPH06500562A (ja)	1994-01-20

Publication	Publication Date	Title
DK1378245T3 (da)	2009-10-26	Transferrin-bindende-proteiner fra neisseria gonorrhoeae og neisseria meningitidis. Deres anvendelse i en vaccine
ATE120093T1 (de)	1995-04-15	Meningococcales klasse i-aussenmembranprotein- vakzin.
ATE162723T1 (de)	1998-02-15	Die induktion der antikörperantwort gegen eigene proteine mit hilfe fremder t-zellepitope
FI103511B (fi)	1999-07-15	Neisseria meningitidisin ulkokalvon proteiinia koodaava nukleotidisekv enssi
CY1109202T1 (el)	2014-07-02	Συνθεσεις που περιεχουν αντιγονα απο τους οροτυπους b και c της neisseria meningitidis οπως και επιπλεον αντιγονα απο τον οροτυπο α
EP0713530A4 (en)	2002-09-18	HIGH-LEVEL EXPRESSION, PURIFICATION AND FOLDING OF GROUP B PORINE PROTEINS FROM NEISSERIA MENINGITIDIS EXTERNAL MEMBRANE
CY1106875T1 (el)	2012-09-26	Αντιγονικα πεπτιδια απο neisseria
DK0503648T3 (da)	2000-10-30	CD2-bindingsdomæne af lymfocytfunktion-associeret antigen 3
BR9811475A (pt)	2000-08-15	Conjugados imunogênicos compreendendo uma porina meningocóccica de grupo b e um polissacarìdeo de h. influenzae
DK0560968T3 (da)	1996-11-25	Vaccine mod infektioner med Neisseria meningitidis
DE69419966D1 (de)	1999-09-16	Impstoff gegen Streptococcus suis-Infektion
DK0754229T3 (da)	1999-07-19	Afamin: et humant serum albumin-lignende protein
ATE105189T1 (de)	1994-05-15	Haemophilus influenzae typ b polysaccharidaussermembranprotein-konjugat als impfstoff.
DE69227984D1 (de)	1999-02-04	Impfstoff, der eine Untereinheit des menschlichen Transferrin-Rezeptors von Neisseria meningitidis enthält
DE69123252D1 (de)	1997-01-02	Kreuzreaktive immunisierung gegen influenza
FI913475A0 (fi)	1991-07-18	Klass ii protein med immunologiska baerar- och foerstaerkningsegenskaper fraon yttermembranen i neisseria meningitidis och vaccin innehaollande detta.
CA2007248A1 (en)	1990-07-06	Meningococcal class 1 outer-membrane protein vaccine