DK1359979T3 - Anticancer-kombination af substituerede pyrroler og paclitaxel - Google Patents

Anticancer-kombination af substituerede pyrroler og paclitaxel

Info

Publication number
DK1359979T3
DK1359979T3 DK02714140T DK02714140T DK1359979T3 DK 1359979 T3 DK1359979 T3 DK 1359979T3 DK 02714140 T DK02714140 T DK 02714140T DK 02714140 T DK02714140 T DK 02714140T DK 1359979 T3 DK1359979 T3 DK 1359979T3
Authority
DK
Denmark
Prior art keywords
paclitaxel
anticancer combination
pyrrols
substituted
substituted pyrrols
Prior art date
Application number
DK02714140T
Other languages
English (en)
Inventor
Lars Holger Breimer
Kapil Dhingra
Urvashi Hooda Dhingra
Steve Ritland
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of DK1359979T3 publication Critical patent/DK1359979T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404Indoles, e.g. pindolol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK02714140T 2001-02-09 2002-02-01 Anticancer-kombination af substituerede pyrroler og paclitaxel DK1359979T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US26787401P 2001-02-09 2001-02-09

Publications (1)

Publication Number Publication Date
DK1359979T3 true DK1359979T3 (da) 2006-08-28

Family

ID=23020488

Family Applications (1)

Application Number Title Priority Date Filing Date
DK02714140T DK1359979T3 (da) 2001-02-09 2002-02-01 Anticancer-kombination af substituerede pyrroler og paclitaxel

Country Status (17)

Country Link
US (1) US6548531B2 (da)
EP (1) EP1359979B1 (da)
JP (1) JP4128872B2 (da)
KR (1) KR100542069B1 (da)
CN (1) CN1265786C (da)
AR (2) AR035429A1 (da)
AT (1) ATE324145T1 (da)
AU (1) AU2002246080B2 (da)
BR (1) BR0206954A (da)
CA (1) CA2435921C (da)
DE (1) DE60210926T2 (da)
DK (1) DK1359979T3 (da)
ES (1) ES2261648T3 (da)
MX (1) MXPA03007036A (da)
PT (1) PT1359979E (da)
WO (1) WO2002064214A2 (da)
ZA (1) ZA200305967B (da)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004529904A (ja) * 2001-03-14 2004-09-30 ブリストル−マイヤーズ スクイブ カンパニー 増殖性疾患の治療のためのエポシロン類似体および化学療法剤の組み合わせ
EP1404334A4 (en) * 2001-05-15 2005-02-02 Faulk Pharmaceuticals Inc TARGETED ADMINISTRATION OF BIOACTIVE COMPOUNDS FOR THE TREATMENT OF CANCER
EP1395273B1 (en) * 2001-05-15 2006-07-19 Faulk Pharmaceuticals, Inc. Targeted delivery of drugs for the treatment of viral infections
WO2002102373A1 (en) * 2001-06-15 2002-12-27 F. Hoffmann-La Roche Ag Method for administration of cancer therapeutic
US20030139373A1 (en) * 2001-11-20 2003-07-24 Breimer Lars Holger Method for cancer therapy
PL1853250T3 (pl) * 2005-02-18 2012-03-30 Abraxis Bioscience Llc Kombinacje i sposoby podawania środków terapeutycznych oraz terapia skojarzona
US8735394B2 (en) * 2005-02-18 2014-05-27 Abraxis Bioscience, Llc Combinations and modes of administration of therapeutic agents and combination therapy
KR20130028728A (ko) 2010-03-29 2013-03-19 아브락시스 바이오사이언스, 엘엘씨 암의 치료 방법
WO2011123393A1 (en) 2010-03-29 2011-10-06 Abraxis Bioscience, Llc Methods of enhancing drug delivery and effectiveness of therapeutic agents
MX347225B (es) 2010-06-04 2017-04-19 Abraxis Bioscience Llc * Metodos de tratamiento contra el cancer pancreatico.
TW201613576A (en) 2014-06-26 2016-04-16 Novartis Ag Intermittent dosing of MDM2 inhibitor
PT3541387T (pt) 2016-11-15 2021-07-14 Novartis Ag Dose e regime para inibidores de interação de hdm2-p53

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL89167A (en) 1988-02-10 1994-02-27 Hoffmann La Roche Substituted pyrroles, their manufacture and pharmaceutical compositions containing them
US6080777A (en) * 1992-01-31 2000-06-27 The Trustees Of Columbia University In The City Of New York Taxol as a radiation sensitizer
CA2086874E (en) 1992-08-03 2000-01-04 Renzo Mauro Canetta Methods for administration of taxol
CA2140653A1 (en) * 1992-08-12 1994-03-03 Irene Abraham Protein kinase inhibitors and related compounds combined with taxol
ES2203111T3 (es) 1998-03-17 2004-04-01 F. Hoffmann-La Roche Ag Maleimidas bisindol sustituidas para la inhibicion de proloferacion celular.
AU3965699A (en) * 1998-04-24 1999-11-16 Mitokor Compounds and methods for treating mitochondria-associated diseases
US6277844B1 (en) * 1998-09-14 2001-08-21 Sydney Spector Compound for selective treatment of malignant cells by inhibiting cell cycle progression, decreasing Bcl2, and increasing apoptosis
US6350786B1 (en) 1998-09-22 2002-02-26 Hoffmann-La Roche Inc. Stable complexes of poorly soluble compounds in ionic polymers
US6335194B1 (en) * 1998-09-29 2002-01-01 Isis Pharmaceuticals, Inc. Antisense modulation of survivin expression

Also Published As

Publication number Publication date
US20020156118A1 (en) 2002-10-24
JP2004517961A (ja) 2004-06-17
PT1359979E (pt) 2006-08-31
AR098745A2 (es) 2016-06-08
EP1359979B1 (en) 2006-04-26
CN1265786C (zh) 2006-07-26
AR035429A1 (es) 2004-05-26
ES2261648T3 (es) 2006-11-16
WO2002064214A2 (en) 2002-08-22
MXPA03007036A (es) 2003-11-18
DE60210926D1 (de) 2006-06-01
ZA200305967B (en) 2005-01-26
CA2435921C (en) 2009-12-22
WO2002064214A8 (en) 2004-02-19
CA2435921A1 (en) 2002-08-22
CN1491126A (zh) 2004-04-21
ATE324145T1 (de) 2006-05-15
WO2002064214A3 (en) 2003-05-30
DE60210926T2 (de) 2007-01-11
KR100542069B1 (ko) 2006-01-11
EP1359979A2 (en) 2003-11-12
US6548531B2 (en) 2003-04-15
KR20040025894A (ko) 2004-03-26
AU2002246080C1 (en) 2002-08-28
BR0206954A (pt) 2004-02-25
JP4128872B2 (ja) 2008-07-30
AU2002246080B2 (en) 2006-08-10

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