DK133682B - Analogous process for the preparation of 3alpha-hydroxy-5alpha-pregn-1-en-20-ones or 3alpha-hydroxy-17beta-alkoxycarbonyl-5alpha-androst-1-ones. - Google Patents

Analogous process for the preparation of 3alpha-hydroxy-5alpha-pregn-1-en-20-ones or 3alpha-hydroxy-17beta-alkoxycarbonyl-5alpha-androst-1-ones.

Info

Publication number
DK133682B
DK133682B DK614771AA DK614771A DK133682B DK 133682 B DK133682 B DK 133682B DK 614771A A DK614771A A DK 614771AA DK 614771 A DK614771 A DK 614771A DK 133682 B DK133682 B DK 133682B
Authority
DK
Denmark
Prior art keywords
3alpha
5alpha
hydroxy
ones
17beta
Prior art date
Application number
DK614771AA
Other languages
Danish (da)
Other versions
DK133682C (en
Inventor
Martin Christopher Cook
Robin Lawrence
Gordon Hanley Phillipps
Anne Christine Hunter
Christopher Earle Newall
Leslie Stephenson
Niall Galbraith Weir
Original Assignee
Glaxo Lab Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB6006470A external-priority patent/GB1380246A/en
Application filed by Glaxo Lab Ltd filed Critical Glaxo Lab Ltd
Priority to DK14674A priority Critical patent/DK135315B/en
Publication of DK133682B publication Critical patent/DK133682B/en
Application granted granted Critical
Publication of DK133682C publication Critical patent/DK133682C/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J3/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J75/00—Processes for the preparation of steroids in general

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
DK614771AA 1970-12-17 1971-12-16 Analogous process for the preparation of 3alpha-hydroxy-5alpha-pregn-1-en-20-ones or 3alpha-hydroxy-17beta-alkoxycarbonyl-5alpha-androst-1-ones. DK133682B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DK14674A DK135315B (en) 1970-12-17 1974-01-11 Analogous process for the preparation of anesthetically active 3alpha-hydroxy-11,20-dioxo-5alpha-pregnanes.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB6006470A GB1380246A (en) 1970-12-17 1970-12-17 3alpha-hydroxy-androstanes and esters thereof

Publications (2)

Publication Number Publication Date
DK133682B true DK133682B (en) 1976-06-28
DK133682C DK133682C (en) 1976-12-20

Family

ID=10484935

Family Applications (1)

Application Number Title Priority Date Filing Date
DK614771AA DK133682B (en) 1970-12-17 1971-12-16 Analogous process for the preparation of 3alpha-hydroxy-5alpha-pregn-1-en-20-ones or 3alpha-hydroxy-17beta-alkoxycarbonyl-5alpha-androst-1-ones.

Country Status (9)

Country Link
AU (1) AU473167B2 (en)
BE (1) BE776786A (en)
CA (1) CA988508A (en)
CH (1) CH616691A5 (en)
DE (1) DE2162555A1 (en)
DK (1) DK133682B (en)
FR (1) FR2118117B1 (en)
IL (1) IL38376A (en)
ZA (1) ZA718466B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1434919A (en) * 1972-06-15 1976-05-12 Glaxo Lab Ltd 3alpha-hydroxy androstanes
US5232917A (en) * 1987-08-25 1993-08-03 University Of Southern California Methods, compositions, and compounds for allosteric modulation of the GABA receptor by members of the androstane and pregnane series
AU698834B2 (en) * 1993-05-24 1998-11-12 Purdue Pharma Ltd. Methods and compositions for inducing sleep
WO2003079972A2 (en) 2002-02-22 2003-10-02 New River Parmaceuticals Inc. Active agent delivery systems and methods for protecting and administering active agents

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH273860A (en) * 1942-04-25 1951-02-28 Nv Organon Process for the preparation of a compound of the cyclopentanopolyhydrophenanthrene series which contains an oxygen-containing group in ring C.
US2824871A (en) * 1951-11-29 1958-02-25 Upjohn Co Steroid compounds and process
FR1281205A (en) * 1956-12-21 1962-01-12 Organon Nv Process for obtaining compounds of the pregnane series

Also Published As

Publication number Publication date
AU3696271A (en) 1973-06-21
ZA718466B (en) 1973-08-29
AU473167B2 (en) 1976-06-17
DK133682C (en) 1976-12-20
BE776786A (en) 1972-06-16
FR2118117B1 (en) 1975-12-26
IL38376A0 (en) 1972-02-29
DE2162555A1 (en) 1972-06-22
CH616691A5 (en) 1980-04-15
IL38376A (en) 1977-07-31
FR2118117A1 (en) 1972-07-28
CA988508A (en) 1976-05-04

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