DK133679C - ANALOGICAL PROCEDURE FOR THE PREPARATION OF PENICILLINS OR SALTS THEREOF - Google Patents

ANALOGICAL PROCEDURE FOR THE PREPARATION OF PENICILLINS OR SALTS THEREOF

Info

Publication number
DK133679C
DK133679C DK251071A DK251071A DK133679C DK 133679 C DK133679 C DK 133679C DK 251071 A DK251071 A DK 251071A DK 251071 A DK251071 A DK 251071A DK 133679 C DK133679 C DK 133679C
Authority
DK
Denmark
Prior art keywords
penicillins
salts
preparation
analogical procedure
analogical
Prior art date
Application number
DK251071A
Other languages
Danish (da)
Other versions
DK133679B (en
Inventor
H B Konig
W Schrock
H Disselnkotter
K G Metzger
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE2025414A external-priority patent/DE2025414C3/en
Priority claimed from DE19712104580 external-priority patent/DE2104580C3/en
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of DK133679B publication Critical patent/DK133679B/en
Application granted granted Critical
Publication of DK133679C publication Critical patent/DK133679C/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D499/00Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/21Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a nitrogen atom directly attached in position 6 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D499/44Compounds with an amino radical acylated by carboxylic acids, attached in position 6
    • C07D499/48Compounds with an amino radical acylated by carboxylic acids, attached in position 6 with a carbon chain, substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, attached to the carboxamido radical
    • C07D499/58Compounds with an amino radical acylated by carboxylic acids, attached in position 6 with a carbon chain, substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, attached to the carboxamido radical substituted in alpha-position to the carboxamido radical
    • C07D499/64Compounds with an amino radical acylated by carboxylic acids, attached in position 6 with a carbon chain, substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, attached to the carboxamido radical substituted in alpha-position to the carboxamido radical by nitrogen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • A61K31/429Thiazoles condensed with heterocyclic ring systems
    • A61K31/43Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/30Oxygen or sulfur atoms
    • C07D233/32One oxygen atom
    • C07D233/38One oxygen atom with acyl radicals or hetero atoms directly attached to ring nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/68Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D499/00Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/21Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a nitrogen atom directly attached in position 6 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D499/44Compounds with an amino radical acylated by carboxylic acids, attached in position 6
    • C07D499/48Compounds with an amino radical acylated by carboxylic acids, attached in position 6 with a carbon chain, substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, attached to the carboxamido radical
    • C07D499/58Compounds with an amino radical acylated by carboxylic acids, attached in position 6 with a carbon chain, substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, attached to the carboxamido radical substituted in alpha-position to the carboxamido radical
    • C07D499/64Compounds with an amino radical acylated by carboxylic acids, attached in position 6 with a carbon chain, substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, attached to the carboxamido radical substituted in alpha-position to the carboxamido radical by nitrogen atoms
    • C07D499/68Compounds with an amino radical acylated by carboxylic acids, attached in position 6 with a carbon chain, substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, attached to the carboxamido radical substituted in alpha-position to the carboxamido radical by nitrogen atoms with aromatic rings as additional substituents on the carbon chain

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DK251071A 1970-05-25 1971-05-24 ANALOGICAL PROCEDURE FOR THE PREPARATION OF PENICILLINS OR SALTS THEREOF DK133679C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE2025414A DE2025414C3 (en) 1970-05-25 1970-05-25 Cyclic acylureidophenylacetamidopenicillanic acids
DE19712104580 DE2104580C3 (en) 1971-02-01 1971-02-01 Acylureidopenicillins

Publications (2)

Publication Number Publication Date
DK133679B DK133679B (en) 1976-06-28
DK133679C true DK133679C (en) 1976-11-15

Family

ID=25759178

Family Applications (1)

Application Number Title Priority Date Filing Date
DK251071A DK133679C (en) 1970-05-25 1971-05-24 ANALOGICAL PROCEDURE FOR THE PREPARATION OF PENICILLINS OR SALTS THEREOF

Country Status (28)

Country Link
JP (1) JPS5538357B1 (en)
AR (2) AR195267A1 (en)
AT (1) AT307617B (en)
BE (1) BE767647A (en)
BG (1) BG23220A3 (en)
CA (1) CA943128A (en)
CH (1) CH562249A5 (en)
CS (1) CS171230B2 (en)
CY (1) CY829A (en)
DD (1) DD91497B3 (en)
DK (1) DK133679C (en)
EG (1) EG10856A (en)
ES (4) ES391532A1 (en)
FI (1) FI54484C (en)
FR (1) FR2100681B1 (en)
GB (1) GB1301961A (en)
HU (1) HU162205B (en)
IE (1) IE35311B1 (en)
IL (1) IL36905A (en)
KE (1) KE2592A (en)
LU (1) LU63203A1 (en)
NL (1) NL172660C (en)
NO (1) NO141164C (en)
PH (1) PH14794A (en)
RO (2) RO59157A (en)
SE (1) SE395896B (en)
SU (1) SU472507A3 (en)
YU (1) YU130271A (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2354219A1 (en) * 1973-10-30 1975-05-07 Bayer Ag BETA-LACTAM-ANTIBIOTICA, A PROCESS FOR THEIR MANUFACTURING AND ITS USE AS A MEDICINAL PRODUCT
US4039673A (en) 1973-10-30 1977-08-02 Bayer Aktiengesellschaft Penicillins and cephalosporins and their production
GB1486349A (en) * 1974-11-28 1977-09-21 Bayer Ag Beta-lactam antibiotics process for their preparation and their use as medicaments
GB1584400A (en) * 1976-12-24 1981-02-11 Bayer Ag (2-oxo-imidazoliden-1-yl(carbonylamino)-acetamido-cephalosporins and penicillins
DE2658906A1 (en) * 1976-12-24 1978-07-06 Bayer Ag BETA-LACTAM ANTIBIOTICS, THE METHOD OF MANUFACTURING AND THEIR USE AS A MEDICINAL PRODUCT
CA1133896A (en) * 1978-05-26 1982-10-19 Nobuhiro Oi Penicillanic acid derivative and process for preparing the same
JPS5732289A (en) 1980-08-05 1982-02-20 Chugai Pharmaceut Co Ltd Alpha-substituted ureidobenzylpenicillin

Also Published As

Publication number Publication date
IE35311B1 (en) 1976-01-07
KE2592A (en) 1976-01-09
RO62689A (en) 1978-05-15
CY829A (en) 1976-03-19
IL36905A (en) 1975-11-25
YU130271A (en) 1982-02-25
DD91497B3 (en) 1988-01-27
NO141164B (en) 1979-10-15
PH14794A (en) 1981-12-09
ES403126A1 (en) 1975-05-01
GB1301961A (en) 1973-01-04
JPS5538357B1 (en) 1980-10-03
DD91497A5 (en) 1972-07-20
ES391532A1 (en) 1974-10-01
AR195946A1 (en) 1973-11-15
RO59157A (en) 1976-04-15
FR2100681A1 (en) 1972-03-24
IL36905A0 (en) 1971-07-28
AR195267A1 (en) 1973-09-28
ES403125A1 (en) 1975-12-16
ES403124A1 (en) 1976-01-01
SU472507A3 (en) 1975-05-30
CS171230B2 (en) 1976-10-29
NO141164C (en) 1980-01-23
SE395896B (en) 1977-08-29
NL7107175A (en) 1971-11-29
DK133679B (en) 1976-06-28
LU63203A1 (en) 1971-09-01
BE767647A (en) 1971-11-25
IE35311L (en) 1971-11-25
EG10856A (en) 1977-05-31
NL172660C (en) 1983-10-03
NL172660B (en) 1983-05-02
BG23220A3 (en) 1977-07-12
FI54484C (en) 1978-12-11
CA943128A (en) 1974-03-05
FI54484B (en) 1978-08-31
CH562249A5 (en) 1975-05-30
AT307617B (en) 1973-05-25
FR2100681B1 (en) 1974-10-18
HU162205B (en) 1973-01-29

Similar Documents

Publication Publication Date Title
DK134992C (en) ANALOGICAL PROCEDURE FOR THE PREPARATION OF PENICILLINS OR SALTS THEREOF
DK135585C (en) ANALOGICAL PROCEDURE FOR THE PREPARATION OF CYCLOHEPTENER DERIVATIVES OR ACID ADDITIONAL SALTS THEREOF
DK132172C (en) ANALOGICAL PROCEDURE FOR THE PREPARATION OF 6,7-BENZOMORPHANES OR SALTS THEREOF
DK140481B (en) ANALOGICAL PROCEDURE FOR THE PREPARATION OF PRESENT PERICILLINESTERS OR SALTS THEREOF
DK136654C (en) ANALOGICAL PROCEDURE FOR THE PREPARATION OF AZEPIN DERIVATIVES OR SALTS THEREOF
DK138855C (en) ANALOGICAL PROCEDURE FOR THE PREPARATION OF PENICILLINS OR NON-TOXIC PHARMACEUTICAL ACCEPTABLE SALTS THEREOF
DK129650B (en) Analogous process for the preparation of 1-phenoxy-2-hydroxy-3-amino-propanes or salts thereof.
DK138646C (en) ANALOGICAL PROCEDURE FOR THE PREPARATION OF N-SUBSTITUTED IMIDAZOLES OR SALTS THEREOF
DK133679C (en) ANALOGICAL PROCEDURE FOR THE PREPARATION OF PENICILLINS OR SALTS THEREOF
DK136468C (en) ANALOGICAL PROCEDURE FOR THE PREPARATION OF 1-ETHYLIMIDAZOLES OR SALTS THEREOF
DK134438B (en) ANALOGICAL PROCEDURE FOR THE PREPARATION OF PENICILLINS OR SALTS THEREOF
DK131639C (en) PROCEDURE FOR THE PREPARATION OF 7BETA- (D-5-AMINO-5-CARBOXYVALERAMIDO) -3- (CARBAMOYLOXYMETHYL) -7-METHOXY-3-CEPHEM-4-CARBOXYLIC ACID OR SALPER ACALPH
DK133153C (en) ANALOGICAL PROCEDURE FOR THE PREPARATION OF TETRAHYDROCYCLOPROPADIBENZAZEPIN DERIVATIVES OR SALTS THEREOF
DK132084C (en) ANALOGICAL PROCEDURE FOR THE PREPARATION OF PENICILLINS OR SALTS THEREOF
DK133301C (en) ANALOGICAL PROCEDURE FOR THE PREPARATION OF PENICILLAN COMPOUNDS OR SALTS THEREOF
DK137011B (en) ANALOGICAL PROCEDURE FOR THE PREPARATION OF OXAZOLES OR SALTS THEREOF
DK139427C (en) PROCEDURE FOR THE PREPARATION OF BENZENESULPHONYLURIN SUBSTANCES OR SALTS THEREOF
DK143104C (en) METHOD OF ANALOGUE FOR THE PREPARATION OF ANILINOPHENYLACETAMIDE DERIVATIVES OR SALTS THEREOF
DK131862C (en) ANALOGICAL PROCEDURE FOR THE PREPARATION OF PENICILLINS OR SALTS THEREOF
DK133433C (en) ANALOGICAL PROCEDURE FOR THE PREPARATION OF PENICILLINS OR SALTS THEREOF
DK92477A (en) ANALOGICAL PROCEDURE FOR THE PREPARATION OF SULPHONYLIC MICARBAZIDES OR SALTS thereof
DK138793C (en) ANALOGICAL PROCEDURE FOR THE PREPARATION OF SULPHONYLURIN SUBSTANCES OR SALTS THEREOF
DK132277C (en) ANALOGICAL PROCEDURE FOR PREPARING PENICILLINS OR SALTS THEREOF
DK132702C (en) ANALOGICAL PROCEDURE FOR THE PREPARATION OF 4-NITROPYRAZOLE-5-CARBOXAMIDOXIMER OR SALTS THEREOF
DK132950C (en) ANALOGICAL PROCEDURE FOR THE PREPARATION OF ALFA-AMINOPENICILLIN DERIVATIVES OR SALTS THEREOF