DK1322660T3 - 17a-fluoralkylsteroider, fremgangsmåde til deres fremstilling og farmaceutiske sammensætninger, der indeholder disse forbindelser - Google Patents
17a-fluoralkylsteroider, fremgangsmåde til deres fremstilling og farmaceutiske sammensætninger, der indeholder disse forbindelserInfo
- Publication number
- DK1322660T3 DK1322660T3 DK01982167T DK01982167T DK1322660T3 DK 1322660 T3 DK1322660 T3 DK 1322660T3 DK 01982167 T DK01982167 T DK 01982167T DK 01982167 T DK01982167 T DK 01982167T DK 1322660 T3 DK1322660 T3 DK 1322660T3
- Authority
- DK
- Denmark
- Prior art keywords
- compounds
- processes
- preparation
- pharmaceutical compositions
- compositions containing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0036—Nitrogen-containing hetero ring
- C07J71/0042—Nitrogen only
- C07J71/0047—Nitrogen only at position 2(3)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/16—Masculine contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/26—Androgens
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0003—Androstane derivatives
- C07J1/0033—Androstane derivatives substituted in position 17 alfa and 17 beta
- C07J1/0037—Androstane derivatives substituted in position 17 alfa and 17 beta the substituent in position 17 alfa being a saturated hydrocarbon group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0051—Estrane derivatives
- C07J1/0081—Substituted in position 17 alfa and 17 beta
- C07J1/0085—Substituted in position 17 alfa and 17 beta the substituent in position 17 alfa being a saturated hydrocarbon group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J11/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0036—Nitrogen-containing hetero ring
- C07J71/0057—Nitrogen and oxygen
- C07J71/0063—Nitrogen and oxygen at position 2(3)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0073—Sulfur-containing hetero ring
- C07J71/0078—Sulfur-containing hetero ring containing only sulfur
- C07J71/0084—Episulfides
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Endocrinology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Reproductive Health (AREA)
- Diabetes (AREA)
- Gynecology & Obstetrics (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10049736A DE10049736A1 (de) | 2000-09-29 | 2000-09-29 | 17alpha-Fluoralkylsteroide, Verfahren zu deren Herstellung und diese Verbindungen enthaltende pharmazeutische Zusammensetzungen |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1322660T3 true DK1322660T3 (da) | 2007-01-08 |
Family
ID=7659018
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK01982167T DK1322660T3 (da) | 2000-09-29 | 2001-09-28 | 17a-fluoralkylsteroider, fremgangsmåde til deres fremstilling og farmaceutiske sammensætninger, der indeholder disse forbindelser |
Country Status (29)
Country | Link |
---|---|
US (1) | US20040024231A1 (da) |
EP (1) | EP1322660B1 (da) |
JP (1) | JP2004509971A (da) |
KR (1) | KR20030061815A (da) |
CN (1) | CN1305890C (da) |
AT (1) | ATE338054T1 (da) |
AU (1) | AU1382202A (da) |
BG (1) | BG107763A (da) |
BR (1) | BR0114258A (da) |
CA (1) | CA2422056A1 (da) |
DE (2) | DE10049736A1 (da) |
DK (1) | DK1322660T3 (da) |
EA (1) | EA005772B1 (da) |
EE (1) | EE200300124A (da) |
ES (1) | ES2272550T3 (da) |
HK (1) | HK1061860A1 (da) |
HR (1) | HRP20030334A2 (da) |
HU (1) | HUP0301198A2 (da) |
IL (2) | IL154828A0 (da) |
MX (1) | MXPA03002606A (da) |
NO (1) | NO325058B1 (da) |
NZ (1) | NZ524781A (da) |
PL (1) | PL361666A1 (da) |
PT (1) | PT1322660E (da) |
SK (1) | SK5192003A3 (da) |
UA (1) | UA76125C2 (da) |
WO (1) | WO2002026759A2 (da) |
YU (1) | YU22903A (da) |
ZA (1) | ZA200303216B (da) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6667299B1 (en) * | 2000-03-16 | 2003-12-23 | Hollis-Eden Pharmaceuticals, Inc. | Pharmaceutical compositions and treatment methods |
US20050182322A1 (en) * | 2004-02-17 | 2005-08-18 | Liebel-Flarsheim Company | Injector auto purge |
EP1854465A1 (en) * | 2006-05-12 | 2007-11-14 | Alexander Tobias Teichmann | Use of 4,17 beta-dihydroxyandrost-4-ene-3-one for treating cancers |
DE102006054535A1 (de) * | 2006-11-15 | 2008-05-21 | Bayer Schering Pharma Aktiengesellschaft | Progesteronrezeptorantagonisten |
KR101044794B1 (ko) * | 2011-01-05 | 2011-06-27 | 연규백 | 복합판넬에 브이 홈을 컷팅하는 장치 |
CN102964411B (zh) * | 2012-12-03 | 2015-04-22 | 华中药业股份有限公司 | 一种雄甾-4,6-二烯-17α-甲基-17β-醇-3-酮的合成方法 |
CN114409717B (zh) * | 2021-12-17 | 2023-03-17 | 湖南科益新生物医药有限公司 | 替勃龙中间体醚化物和替勃龙的制备方法 |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3029261A (en) * | 1959-11-30 | 1962-04-10 | Syntex Sa | Steroidal fluoro compounds and process for the production thereof |
US3046273A (en) * | 1961-01-18 | 1962-07-24 | Merck & Co Inc | Novel 17alpha-trifluoro-propynyl androstenes and processes |
US3255182A (en) * | 1961-02-13 | 1966-06-07 | Merck & Co Inc | 17alpha-haloethynyl-[3, 2-c]pyrazolo androstenes and intermediates therefor |
CH431508A (de) * | 1961-06-16 | 1967-03-15 | Ciba Geigy | Verfahren zur Ketalisierung der 3-Oxogruppe in 5(10)-3-Oxo-19-nor-steroiden |
US3098851A (en) * | 1961-11-20 | 1963-07-23 | Searle & Co | 17alpha-alkynyl-2beta-halo-5alpha-androstane-3alpha, 17beta-diols, esters thereof, and intermediates thereto |
US3092623A (en) * | 1961-12-01 | 1963-06-04 | Merck & Co Inc | [3, 2-c] pyrazolo-4, 9-androstadienes |
US3076825A (en) * | 1962-02-14 | 1963-02-05 | Syntex Corp | 17alpha-(1'-fluoroethyl) and 17alpha-(1', 1'-difluoroethyl) androstane derivatives and process therefor |
US3340251A (en) * | 1965-10-18 | 1967-09-05 | Merck & Co Inc | 17beta-hydroxy-17alpha-halohydrocarbon-19-nor-androst-4-ene-3-ones and the delta5(10)-isomers thereof |
AU3257993A (en) * | 1991-12-22 | 1993-07-28 | Schering Aktiengesellschaft | 3-methylsulphonylhydrazono and 3-oxyimino steroids, a method of preparing them, pharmaceutical preparations containing them and their use in the preparation of drugs |
CN1072678C (zh) * | 1994-05-30 | 2001-10-10 | 中国科学院上海有机化学研究所 | 三氟甲基甾体化合物、制备及其用途 |
DE19706061A1 (de) * | 1997-02-07 | 1998-08-13 | Schering Ag | Antigestagen wirksame Steroide mit fluorierter 17alpha-Alkylkette |
DE19860719A1 (de) * | 1998-12-23 | 2000-06-29 | Schering Ag | Neue Testosteronderivate und ihre Verwendung zur Langzeittherapie von Androgen-abhängigen Erkrankungen |
DE10221034A1 (de) * | 2002-05-03 | 2003-11-20 | Schering Ag | 17alpha-Fluoralkyl-11ß-benzaldoxim-Steroide, Verfahren zu deren Herstellung, diese Steroide enthaltende pharmazeutische Präparate sowie deren Verwendung zur Herstellung von Arzneimitteln |
-
2000
- 2000-09-29 DE DE10049736A patent/DE10049736A1/de not_active Withdrawn
-
2001
- 2001-09-28 EP EP01982167A patent/EP1322660B1/de not_active Expired - Lifetime
- 2001-09-28 PL PL01361666A patent/PL361666A1/xx unknown
- 2001-09-28 NZ NZ524781A patent/NZ524781A/en unknown
- 2001-09-28 YU YU22903A patent/YU22903A/sh unknown
- 2001-09-28 DK DK01982167T patent/DK1322660T3/da active
- 2001-09-28 CA CA002422056A patent/CA2422056A1/en not_active Abandoned
- 2001-09-28 WO PCT/DE2001/003732 patent/WO2002026759A2/de active IP Right Grant
- 2001-09-28 JP JP2002531142A patent/JP2004509971A/ja active Pending
- 2001-09-28 EE EEP200300124A patent/EE200300124A/xx unknown
- 2001-09-28 UA UA2003043904A patent/UA76125C2/uk unknown
- 2001-09-28 PT PT01982167T patent/PT1322660E/pt unknown
- 2001-09-28 MX MXPA03002606A patent/MXPA03002606A/es active IP Right Grant
- 2001-09-28 AU AU1382202A patent/AU1382202A/xx not_active Withdrawn
- 2001-09-28 HU HU0301198A patent/HUP0301198A2/hu unknown
- 2001-09-28 BR BR0114258-5A patent/BR0114258A/pt not_active IP Right Cessation
- 2001-09-28 ES ES01982167T patent/ES2272550T3/es not_active Expired - Lifetime
- 2001-09-28 KR KR10-2003-7004483A patent/KR20030061815A/ko active IP Right Grant
- 2001-09-28 CN CNB018165494A patent/CN1305890C/zh not_active Expired - Fee Related
- 2001-09-28 AT AT01982167T patent/ATE338054T1/de not_active IP Right Cessation
- 2001-09-28 US US10/381,789 patent/US20040024231A1/en not_active Abandoned
- 2001-09-28 DE DE50110892T patent/DE50110892D1/de not_active Expired - Fee Related
- 2001-09-28 EA EA200300400A patent/EA005772B1/ru not_active IP Right Cessation
- 2001-09-28 IL IL15482801A patent/IL154828A0/xx active IP Right Grant
- 2001-09-28 SK SK519-2003A patent/SK5192003A3/sk unknown
-
2003
- 2003-03-10 IL IL154828A patent/IL154828A/en not_active IP Right Cessation
- 2003-03-28 NO NO20031444A patent/NO325058B1/no unknown
- 2003-04-24 ZA ZA200303216A patent/ZA200303216B/en unknown
- 2003-04-25 BG BG107763A patent/BG107763A/bg unknown
- 2003-04-28 HR HR20030334A patent/HRP20030334A2/hr not_active Application Discontinuation
-
2004
- 2004-07-06 HK HK04104883A patent/HK1061860A1/xx not_active IP Right Cessation
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE60204452D1 (de) | Pyrazolo[1,5]pyridinderivate | |
DE60009511D1 (de) | Nematizide trifluorbutene | |
DE60112330D1 (en) | Pyrazolopyridinderivate | |
DK0712311T3 (da) | Antiglucocorticoidsteroider til behandling af angstlidelser | |
ATE289318T1 (de) | 17alfa, 21-dihydroxypregnene esters als antiandrogene wirkstoffe | |
DK1322660T3 (da) | 17a-fluoralkylsteroider, fremgangsmåde til deres fremstilling og farmaceutiske sammensætninger, der indeholder disse forbindelser | |
BR0308601A (pt) | inibidores de carboxipeptidase b de plasma | |
DE60201074D1 (en) | Pyrazolopyridinderivate | |
SE9904128D0 (sv) | Novel compounds | |
DK1235850T3 (da) | Umættede 14,15-cyclopropano-androstaner, fremgangsmåde til deres fremstilling og farmaceutiske præparater indeholdende disse forbindelser | |
DK1196428T3 (da) | 11-beta-aryl-17,17-spirothiolan-substituerede steroider | |
EA200600120A1 (ru) | ЧИСТЫЕ ИЗОМЕРЫ d-(17α)-13-ЭТИЛ-17-ГИДРОКСИ-18,19-ДИНОРПРЕГН-4-ЕН-20-ИН-3-ОН-3E И 3Z-ОКСИМОВ, СПОСОБ СИНТЕЗА СМЕСИ ИЗОМЕРОВ И ЧИСТЫХ ИЗОМЕРОВ | |
AP1579A (en) | Novel 17-Halogenated 19-nor steroids, method and intermediates for preparing same, use as medicines and pharmaceutical compositions containing same. | |
DK1242445T3 (da) | 14, 15-Cycolopropanosteroider fra 19-norandrostan-rækken, fremgangsmåde til deres fremstilling og farmaceutiske sammensætnining indeholdende disse forbindelser | |
TW200603812A (en) | D-homo-17-chlor-16(17)-ene steroids |