DK129234B - Process for the preparation of levo-1-n-butyl-2 ', 6'-pipecoloxylidide. - Google Patents

Process for the preparation of levo-1-n-butyl-2 ', 6'-pipecoloxylidide.

Info

Publication number
DK129234B
DK129234B DK226968AA DK226968A DK129234B DK 129234 B DK129234 B DK 129234B DK 226968A A DK226968A A DK 226968AA DK 226968 A DK226968 A DK 226968A DK 129234 B DK129234 B DK 129234B
Authority
DK
Denmark
Prior art keywords
pipecoloxylidide
levo
butyl
preparation
Prior art date
Application number
DK226968AA
Other languages
Danish (da)
Other versions
DK129234C (en
Inventor
F Luduena
B Tullar
Original Assignee
Sterling Drug Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sterling Drug Inc filed Critical Sterling Drug Inc
Publication of DK129234B publication Critical patent/DK129234B/en
Application granted granted Critical
Publication of DK129234C publication Critical patent/DK129234C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK226968AA 1967-05-18 1968-05-16 Process for the preparation of levo-1-n-butyl-2 ', 6'-pipecoloxylidide. DK129234B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US63927767A 1967-05-18 1967-05-18

Publications (2)

Publication Number Publication Date
DK129234B true DK129234B (en) 1974-09-16
DK129234C DK129234C (en) 1975-02-03

Family

ID=24563449

Family Applications (1)

Application Number Title Priority Date Filing Date
DK226968AA DK129234B (en) 1967-05-18 1968-05-16 Process for the preparation of levo-1-n-butyl-2 ', 6'-pipecoloxylidide.

Country Status (13)

Country Link
AT (2) AT286298B (en)
BE (1) BE715188A (en)
CH (1) CH498834A (en)
DE (1) DE1770408C3 (en)
DK (1) DK129234B (en)
ES (1) ES354352A1 (en)
FI (1) FI50333C (en)
FR (2) FR1583872A (en)
GB (1) GB1180712A (en)
IL (1) IL29958A (en)
NL (1) NL6806995A (en)
NO (1) NO124540B (en)
SE (1) SE341404B (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0151110B1 (en) * 1983-08-01 1989-03-01 Astra Läkemedel Aktiebolag L-n-n-propylpipecolic acid-2,6-xylidide and method for preparing the same
SE451840B (en) * 1986-01-03 1987-11-02 Astra Laekemedel Ab OPTICALLY PURE MONOHYDRATED OF S - (-) - 1-PROPYL-2 ', 6'-PIPECOLOXYLIDE HYDROCHLORIDE, SET TO PREPARE THIS AND PHARMACEUTICAL PREPARATIONS FOR LOCAL ANCHORING
PT788480E (en) * 1994-10-25 2003-12-31 Darwin Discovery Ltd CRYSTALLIZATION OF LEVOBUPIVACAINE AND ITS ANALOGS
SE9501808D0 (en) * 1995-05-16 1995-05-16 Astra Ab New process
KR100844336B1 (en) * 2007-01-16 2008-07-07 하나제약 주식회사 New synthetic method of levobupivacaine and its hydrochloride
WO2014009964A1 (en) * 2012-07-11 2014-01-16 Neon Laboratories Limited Process for enantiomeric enrichment of 2 ', 6 ' - pipecoloxylidide
CN105315196A (en) * 2015-11-28 2016-02-10 山东齐都药业有限公司 High-purity levobupivacaine hydrochloride refining method
CN109896992A (en) * 2017-12-08 2019-06-18 武汉软件工程职业学院 Prepare the method and its application of ionic liquid

Also Published As

Publication number Publication date
DE1770408B2 (en) 1974-04-11
IL29958A (en) 1971-04-28
AT284843B (en) 1970-09-25
IL29958A0 (en) 1968-07-25
FR1583872A (en) 1969-12-05
NL6806995A (en) 1968-11-19
GB1180712A (en) 1970-02-11
FI50333C (en) 1976-02-10
FR8160M (en) 1970-08-24
CH498834A (en) 1970-11-15
SE341404B (en) 1971-12-27
DE1770408A1 (en) 1971-10-21
FI50333B (en) 1975-10-31
NO124540B (en) 1972-05-02
DK129234C (en) 1975-02-03
DE1770408C3 (en) 1974-11-07
ES354352A1 (en) 1969-11-01
BE715188A (en) 1968-09-30
AT286298B (en) 1970-12-10

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