DK1212321T3 - Mellemprodukter til fremstilling af quinolone carboxylsyrederivater - Google Patents

Mellemprodukter til fremstilling af quinolone carboxylsyrederivater

Info

Publication number
DK1212321T3
DK1212321T3 DK00956706T DK00956706T DK1212321T3 DK 1212321 T3 DK1212321 T3 DK 1212321T3 DK 00956706 T DK00956706 T DK 00956706T DK 00956706 T DK00956706 T DK 00956706T DK 1212321 T3 DK1212321 T3 DK 1212321T3
Authority
DK
Denmark
Prior art keywords
intermediates
preparation
carboxylic acid
acid derivatives
quinolone carboxylic
Prior art date
Application number
DK00956706T
Other languages
English (en)
Inventor
Trevor John Grinter
Simon Howie
Original Assignee
Lg Life Sciences Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lg Life Sciences Ltd filed Critical Lg Life Sciences Ltd
Application granted granted Critical
Publication of DK1212321T3 publication Critical patent/DK1212321T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrrole Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK00956706T 1999-09-03 2000-09-01 Mellemprodukter til fremstilling af quinolone carboxylsyrederivater DK1212321T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9920919.9A GB9920919D0 (en) 1999-09-03 1999-09-03 Novel compound
PCT/GB2000/003358 WO2001017961A2 (en) 1999-09-03 2000-09-01 Intermediates for the production of naphthyridine-3-carboxylic acid derivatives
EP00956706A EP1212321B1 (en) 1999-09-03 2000-09-01 Intermediates for the production of naphthyridine-3-carboxylic acid derivatives

Publications (1)

Publication Number Publication Date
DK1212321T3 true DK1212321T3 (da) 2004-10-25

Family

ID=10860355

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00956706T DK1212321T3 (da) 1999-09-03 2000-09-01 Mellemprodukter til fremstilling af quinolone carboxylsyrederivater

Country Status (30)

Country Link
US (3) US6703512B1 (da)
EP (1) EP1212321B1 (da)
JP (1) JP4208463B2 (da)
KR (1) KR100705363B1 (da)
CN (1) CN1255402C (da)
AR (1) AR029452A1 (da)
AT (1) ATE270671T1 (da)
AU (1) AU773698B2 (da)
BR (1) BRPI0013750B8 (da)
CA (1) CA2383751C (da)
CO (1) CO5180620A1 (da)
CZ (1) CZ2002759A3 (da)
DE (1) DE60012028T2 (da)
DK (1) DK1212321T3 (da)
ES (1) ES2223570T3 (da)
GB (1) GB9920919D0 (da)
HK (1) HK1046908B (da)
HU (1) HU229391B1 (da)
IL (2) IL148441A0 (da)
MX (1) MXPA02002356A (da)
MY (1) MY126789A (da)
NO (1) NO322501B1 (da)
NZ (1) NZ517601A (da)
PL (1) PL206491B1 (da)
PT (1) PT1212321E (da)
SI (1) SI1212321T1 (da)
TR (1) TR200200548T2 (da)
TW (1) TWI264435B (da)
WO (1) WO2001017961A2 (da)
ZA (1) ZA200201779B (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2281817C (en) * 1999-06-29 2008-07-29 Smithkline Beecham Corporation Methods of use of fluoroquinolone compounds against maxillary sinus pathogenic bacteria
GB9920919D0 (en) * 1999-09-03 1999-11-10 Sb Pharmco Inc Novel compound
GB9920917D0 (en) 1999-09-03 1999-11-10 Sb Pharmco Inc Novel process
EP1412078B1 (en) 2001-08-02 2008-10-08 LG Life Sciences Limited Processes for the production of amino-protected derivatives of 4-aminomethylene-pyrrolidin-3-one, gemifloxacin or a salt thereof
KR100517638B1 (ko) 2002-04-08 2005-09-28 주식회사 엘지생명과학 게미플록사신 산염의 새로운 제조방법
ATE310773T1 (de) * 2002-07-17 2005-12-15 Ciba Sc Holding Ag Oxidationsverfahren zur herstellung von chinacridonpigmenten
KR100653334B1 (ko) 2003-03-07 2006-12-04 주식회사 엘지생명과학 4-아미노메틸-3-알콕시이미노피롤리딘 메탄설폰산염의 신규한 제조 방법
US8822934B2 (en) * 2006-11-03 2014-09-02 Accuray Incorporated Collimator changer
CN104693088B (zh) * 2013-12-06 2018-01-05 常州市勇毅生物药业有限公司 一种吉米沙星侧链的制备方法

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57134482A (en) 1981-02-13 1982-08-19 Dainippon Pharmaceut Co Ltd 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-1,8- naphthyridine-3-carboxylic acid-3/2 hydrate and its preparation
IN162769B (da) 1984-11-13 1988-07-09 Kyorin Seiyaku Kk
NZ222047A (en) 1986-10-08 1991-01-29 Bristol Myers Co Quinoline - or naphthyridine - carboxylic acid anti-bacterial agents
JPH01100165A (ja) 1987-10-13 1989-04-18 Shionogi & Co Ltd オキシムまたはヒドロキシアミン誘導体系抗菌剤
US4920120A (en) 1988-01-25 1990-04-24 Warner-Lambert Company Antibacterial agents
JPH0356479A (ja) 1989-07-24 1991-03-12 Takeshi Yokota 水溶性キノロン誘導体のp‐トルエンスルホン酸塩
WO1991002526A1 (en) 1989-08-16 1991-03-07 Pfizer Inc. Azabicyclo quinolone carboxylic acids
US5137892A (en) 1990-12-12 1992-08-11 Abbott Laboratories Quinoline, naphthyridine and pyridobenzoxazine derivatives
US5276041A (en) 1991-11-08 1994-01-04 Kaken Pharmaceutical Co., Ltd. Oxime derivatives
JPH0673056A (ja) 1992-08-26 1994-03-15 Kaken Pharmaceut Co Ltd キノリンカルボン酸誘導体およびその塩
US5776944A (en) 1994-06-16 1998-07-07 Lg Chemical Ltd. 7-(4-aminomethyl-3-methyloxyiminopyrroplidin-1-yl)-1-cyclopropyl-6-flu oro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid and the process for the preparation thereof
DK0688772T3 (da) 1994-06-16 1999-11-01 Lg Chemical Ltd Quinolincarboxylsyrederivater med 7-(4-aminomethyl-3-oxim)-pyrrolidinsubstituenter og fremgangsmåde til deres fremstilling
JP3449658B2 (ja) 1994-12-21 2003-09-22 杏林製薬株式会社 安定性に優れた8−アルコキシキノロンカルボン酸水和物並びにその製造方法
DK0789697T3 (da) 1995-06-06 1998-10-19 Pfizer Krystalform af vandfrit 7-([1alfa, 5alfa, 6alfa,]-6-amino-3-azabicyclo[3.1.0]hex-3-yl)-6-fluor-1-(2,4-difluorphenyl)-1,4-d
UA59341C2 (uk) 1995-08-11 2003-09-15 Пфайзер, Інк. (1s,2s)-1-(4-гідроксифеніл)-2-(4-гідрокси-4-фенілпіперидин-1-іл)-1-пропанолметансульфонат тригідрат
UA49880C2 (uk) 1996-03-29 2002-10-15 Смітклайн Бічам Корпорейшн Дигідрат ерпоcартану, фармацевтична композиція, спосіб отримання твердої дозованої форми, спосіб блокування рецепторів ангіотензину іі
MA24500A1 (fr) * 1997-03-21 1998-10-01 Lg Life Sciences Ltd Derive du sel d'acide carboxylique de naphthyridine .
KR100286874B1 (ko) 1998-03-04 2001-04-16 성재갑 보호된 4-아미노메틸-피롤리딘-3-온의 제조방법
US6127400A (en) 1998-05-29 2000-10-03 Pharmacia & Upjohn Company Salts of diamine pyrrolidine
GB9820405D0 (en) 1998-09-18 1998-11-11 Smithkline Beecham Plc Process
PT1223935E (pt) 1999-06-29 2008-04-03 Lg Life Sciences Ltd Utilização de compostos de gemifloxacina contra bactérias
AU6947900A (en) 1999-09-01 2001-03-26 Smithkline Beecham Corporation Methods of use of fluoroquinolone compounds against bacteria
GB9920919D0 (en) 1999-09-03 1999-11-10 Sb Pharmco Inc Novel compound
GB9920917D0 (en) * 1999-09-03 1999-11-10 Sb Pharmco Inc Novel process
AU7709400A (en) 1999-09-22 2001-04-24 Smithkline Beecham Corporation Methods of use of fluoroquinolone compounds against bacteria
KR20010091379A (ko) 2000-03-15 2001-10-23 성재갑 7-(4-아미노메틸-3-옥심)피롤리딘 치환체를 갖는 퀴놀린카르복실산 유도체의 신규 제조방법
KR20020018560A (ko) 2000-09-01 2002-03-08 성재갑 3-아미노메틸-4-z-메톡시이미노피롤리딘의 신규 제조방법

Also Published As

Publication number Publication date
AR029452A1 (es) 2003-07-02
KR20020041423A (ko) 2002-06-01
CN1255402C (zh) 2006-05-10
PT1212321E (pt) 2004-10-29
NO20021043L (no) 2002-03-01
TWI264435B (en) 2006-10-21
PL354725A1 (en) 2004-02-09
HK1046908A1 (en) 2003-01-30
JP2003508517A (ja) 2003-03-04
MY126789A (en) 2006-10-31
US6703512B1 (en) 2004-03-09
BRPI0013750B8 (pt) 2021-05-25
SI1212321T1 (en) 2004-12-31
DE60012028T2 (de) 2005-08-18
AU6857300A (en) 2001-04-10
CZ2002759A3 (cs) 2002-06-12
EP1212321B1 (en) 2004-07-07
NO322501B1 (no) 2006-10-16
WO2001017961A2 (en) 2001-03-15
IL148441A0 (en) 2002-09-12
HUP0202733A2 (hu) 2003-01-28
DE60012028D1 (de) 2004-08-12
IL148441A (en) 2007-03-08
ATE270671T1 (de) 2004-07-15
US6803467B2 (en) 2004-10-12
ZA200201779B (en) 2003-08-27
NZ517601A (en) 2003-08-29
ES2223570T3 (es) 2005-03-01
GB9920919D0 (en) 1999-11-10
HUP0202733A3 (en) 2005-12-28
HK1046908B (zh) 2005-05-27
TR200200548T2 (tr) 2002-09-23
KR100705363B1 (ko) 2007-04-10
BR0013750B1 (pt) 2014-06-17
CO5180620A1 (es) 2002-07-30
CN1372558A (zh) 2002-10-02
AU773698B2 (en) 2004-06-03
CA2383751C (en) 2010-06-29
HU229391B1 (hu) 2013-11-28
US20050033064A1 (en) 2005-02-10
MXPA02002356A (es) 2002-07-30
PL206491B1 (pl) 2010-08-31
EP1212321A2 (en) 2002-06-12
NO20021043D0 (no) 2002-03-01
US20040138292A1 (en) 2004-07-15
JP4208463B2 (ja) 2009-01-14
WO2001017961A3 (en) 2001-09-20
BR0013750A (pt) 2002-05-21
CA2383751A1 (en) 2001-03-15

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