DK1189615T3 - Endoparasiticide synergistic combination containing cyclic depsipeptides and piperazines - Google Patents

Endoparasiticide synergistic combination containing cyclic depsipeptides and piperazines

Info

Publication number
DK1189615T3
DK1189615T3 DK00940235T DK00940235T DK1189615T3 DK 1189615 T3 DK1189615 T3 DK 1189615T3 DK 00940235 T DK00940235 T DK 00940235T DK 00940235 T DK00940235 T DK 00940235T DK 1189615 T3 DK1189615 T3 DK 1189615T3
Authority
DK
Denmark
Prior art keywords
piperazines
endoparasiticide
depsipeptides
cyclic depsipeptides
containing cyclic
Prior art date
Application number
DK00940235T
Other languages
Danish (da)
Inventor
Achim Harder
Samson-Himmelstjerna Georg Von
Original Assignee
Bayer Healthcare Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=7907825&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1189615(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bayer Healthcare Ag filed Critical Bayer Healthcare Ag
Application granted granted Critical
Publication of DK1189615T3 publication Critical patent/DK1189615T3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/15—Depsipeptides; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Steroid Compounds (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

The invention relates to the use of piperazines for potentiating the endoparasiticidal action of cyclic depsipeptides in endoparasiticidal agents. Said depsipeptides are comprised of amino acids and hydroxycarboxylic acids serving as ring structural elements and having 24 ring atoms. The invention also relates to agents of this type and to the use of piperazines and cyclic depsipeptides, said depsipeptides being comprised of amino acids and hydroxycarboxylic acids serving as ring structural elements and having 24 ring atoms, in order to produce endoparasiticidal agents.
DK00940235T 1999-05-12 2000-05-04 Endoparasiticide synergistic combination containing cyclic depsipeptides and piperazines DK1189615T3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19921887A DE19921887A1 (en) 1999-05-12 1999-05-12 Synergistic ectoparasiticide combination for use in human or veterinary medicine, comprising cyclic depsipeptide and piperazine compound as potentiating agent

Publications (1)

Publication Number Publication Date
DK1189615T3 true DK1189615T3 (en) 2004-06-07

Family

ID=7907825

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00940235T DK1189615T3 (en) 1999-05-12 2000-05-04 Endoparasiticide synergistic combination containing cyclic depsipeptides and piperazines

Country Status (26)

Country Link
EP (1) EP1189615B1 (en)
JP (1) JP2002544224A (en)
KR (1) KR100704717B1 (en)
CN (1) CN1224391C (en)
AT (1) ATE258795T1 (en)
AU (1) AU768910B2 (en)
BR (1) BR0010499A (en)
CA (1) CA2373827C (en)
CZ (1) CZ300782B6 (en)
DE (2) DE19921887A1 (en)
DK (1) DK1189615T3 (en)
ES (1) ES2211558T3 (en)
HK (1) HK1047228B (en)
HR (1) HRP20010918B1 (en)
HU (1) HUP0201201A3 (en)
MX (1) MXPA01011455A (en)
NO (1) NO328870B1 (en)
PL (1) PL200951B1 (en)
PT (1) PT1189615E (en)
RS (1) RS50169B (en)
RU (1) RU2250779C2 (en)
SK (1) SK285494B6 (en)
TR (2) TR200401875T2 (en)
UA (1) UA72520C2 (en)
WO (1) WO2000069425A2 (en)
ZA (1) ZA200108238B (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10008128A1 (en) * 2000-02-22 2001-08-23 Bayer Ag Endoparasiticide composition effective on topical administration, comprises solution of depsipeptide in solvent such as 1,2-isopropylidene-glycerol
DE10358525A1 (en) * 2003-12-13 2005-07-07 Bayer Healthcare Ag Endoparasiticides Means for topical application
KR101671325B1 (en) * 2015-01-09 2016-11-02 한국생명공학연구원 Novel cyclic depsipeptide-based compound, separation method thereof, and antibacterial pharmaceutical composition containing the same as an active ingredient
PL3298027T3 (en) 2015-05-20 2021-11-08 Boehringer Ingelheim Animal Health USA Inc. Anthelmintic depsipeptide compounds
AU2016380868B2 (en) * 2015-12-28 2019-11-28 Boehringer Ingelheim Animal Health USA Inc. Anthelmintic depsipeptide compounds
US11382949B2 (en) 2016-11-16 2022-07-12 Boehringer Ingelheim Animal Health USA Inc. Anthelmintic depsipeptide compounds
CA3192377A1 (en) * 2020-09-11 2022-03-17 The Governing Council Of The University Of Toronto Piperazinyl compounds and methods for treating nematode infections

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA842571B (en) * 1983-04-07 1985-11-27 Merck & Co Inc Novel synergistic antiparasitic combinations
JPS6471865A (en) * 1987-09-11 1989-03-16 Nichibai Boeki Kk 1-alkylcarbamoyl-4-methylpiperazine derivative
NO176766C (en) * 1989-02-07 1995-05-24 Meiji Seika Kaisha Process for the preparation of a compound having anthelmintic activity
KR100392172B1 (en) * 1993-09-06 2004-04-03 후지사와 야꾸힝 고교 가부시키가이샤 Cyclic Depsipeptide Compounds
DE4400464A1 (en) * 1994-01-11 1995-07-13 Bayer Ag Endoparasiticidal agents
DE19520275A1 (en) * 1995-06-02 1996-12-05 Bayer Ag Endoparasiticidal agents
CA2228632A1 (en) * 1995-09-07 1997-03-13 William W. Mcwhorter, Jr. Cycloanthelmintic inhibitors
WO1998037088A1 (en) * 1997-02-19 1998-08-27 Meiji Seika Kaisha Ltd. Derivatives of cyclodepsipeptide, pf1022 substance
WO1998055469A1 (en) * 1997-06-04 1998-12-10 Bayer Aktiengesellschaft Desoxycyclodepsipeptides and their use for combatting endoparasites
US6288038B1 (en) * 1998-08-04 2001-09-11 Nisshin Seifun Group Inc. Depsipeptide derivatives bearing piperazinone rings

Also Published As

Publication number Publication date
EP1189615A2 (en) 2002-03-27
BR0010499A (en) 2002-02-13
AU768910B2 (en) 2004-01-08
HK1047228A1 (en) 2003-02-14
HK1047228B (en) 2006-07-21
HUP0201201A3 (en) 2003-03-28
TR200103240T2 (en) 2002-04-22
CN1352559A (en) 2002-06-05
TR200401875T2 (en) 2005-01-24
AU5523700A (en) 2000-12-05
UA72520C2 (en) 2005-03-15
JP2002544224A (en) 2002-12-24
PT1189615E (en) 2004-05-31
WO2000069425A2 (en) 2000-11-23
EP1189615B1 (en) 2004-02-04
KR100704717B1 (en) 2007-04-09
PL200951B1 (en) 2009-02-27
NO20015398L (en) 2001-11-05
CN1224391C (en) 2005-10-26
HRP20010918B1 (en) 2011-01-31
ES2211558T3 (en) 2004-07-16
PL351376A1 (en) 2003-04-07
HUP0201201A2 (en) 2002-08-28
MXPA01011455A (en) 2002-07-30
DE50005213D1 (en) 2004-03-11
RU2250779C2 (en) 2005-04-27
HRP20010918A2 (en) 2003-04-30
KR20010109527A (en) 2001-12-10
ZA200108238B (en) 2002-12-24
DE19921887A1 (en) 2000-11-16
RS50169B (en) 2009-05-06
SK285494B6 (en) 2007-02-01
CZ20014060A3 (en) 2002-06-12
WO2000069425A3 (en) 2001-03-15
CZ300782B6 (en) 2009-08-12
NO328870B1 (en) 2010-06-07
NO20015398D0 (en) 2001-11-05
YU80501A (en) 2004-09-03
SK16262001A3 (en) 2002-03-05
ATE258795T1 (en) 2004-02-15
CA2373827C (en) 2008-09-16
CA2373827A1 (en) 2000-11-23

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