DK116287B - Process for the preparation of 4-alkyl- or 4-alkenyl-5-aryl-1,4-benzodiazepin-2-ones or quaternary ammonium compounds or salts thereof. - Google Patents

Process for the preparation of 4-alkyl- or 4-alkenyl-5-aryl-1,4-benzodiazepin-2-ones or quaternary ammonium compounds or salts thereof.

Info

Publication number
DK116287B
DK116287B DK468762AA DK468762A DK116287B DK 116287 B DK116287 B DK 116287B DK 468762A A DK468762A A DK 468762AA DK 468762 A DK468762 A DK 468762A DK 116287 B DK116287 B DK 116287B
Authority
DK
Denmark
Prior art keywords
benzodiazepin
alkenyl
aryl
ones
salts
Prior art date
Application number
DK468762AA
Other languages
Danish (da)
Inventor
E Reeder
L Sternbach
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US149527A external-priority patent/US3136815A/en
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of DK116287B publication Critical patent/DK116287B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24—Oxygen atoms
    • C07D243/26—Preparation from compounds already containing the benzodiazepine skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK468762AA 1961-11-02 1962-10-30 Process for the preparation of 4-alkyl- or 4-alkenyl-5-aryl-1,4-benzodiazepin-2-ones or quaternary ammonium compounds or salts thereof. DK116287B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US149527A US3136815A (en) 1959-12-10 1961-11-02 Amino substituted benzophenone oximes and derivatives thereof

Publications (1)

Publication Number Publication Date
DK116287B true DK116287B (en) 1969-12-29

Family

ID=22530691

Family Applications (2)

Application Number Title Priority Date Filing Date
DK468762AA DK116287B (en) 1961-11-02 1962-10-30 Process for the preparation of 4-alkyl- or 4-alkenyl-5-aryl-1,4-benzodiazepin-2-ones or quaternary ammonium compounds or salts thereof.
DK468862AA DK116365B (en) 1961-11-02 1962-10-30 Process for the preparation of 1,4-benzodiazepine derivatives or salts thereof.

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK468862AA DK116365B (en) 1961-11-02 1962-10-30 Process for the preparation of 1,4-benzodiazepine derivatives or salts thereof.

Country Status (8)

Country Link
BE (2) BE624169A (en)
BR (1) BR6244259D0 (en)
CH (2) CH420177A (en)
DK (2) DK116287B (en)
ES (2) ES282087A1 (en)
FR (1) FR2979M (en)
GB (2) GB988634A (en)
SE (2) SE301980B (en)

Also Published As

Publication number Publication date
FR2979M (en) 1964-12-07
ES282088A1 (en) 1963-03-16
GB988635A (en) 1965-04-07
CH420177A (en) 1966-09-15
SE302126B (en) 1968-07-08
BR6244259D0 (en) 1973-05-24
SE301980B (en) 1968-07-01
CH420176A (en) 1966-09-15
DE1445866A1 (en) 1969-03-13
ES282087A1 (en) 1963-03-16
GB988634A (en) 1965-04-07
DE1445865A1 (en) 1969-03-13
BE624168A (en) 1963-04-29
BE624169A (en) 1963-04-29
DK116365B (en) 1970-01-05

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