DK108589D0 - Chimere antistoffer rettet mod humant carcinoembryonalt antigen samt dna-sekvenser, der koder for saadanne antistoffer - Google Patents
Chimere antistoffer rettet mod humant carcinoembryonalt antigen samt dna-sekvenser, der koder for saadanne antistofferInfo
- Publication number
- DK108589D0 DK108589D0 DK108589A DK108589A DK108589D0 DK 108589 D0 DK108589 D0 DK 108589D0 DK 108589 A DK108589 A DK 108589A DK 108589 A DK108589 A DK 108589A DK 108589 D0 DK108589 D0 DK 108589D0
- Authority
- DK
- Denmark
- Prior art keywords
- antibodies
- chimerary
- humant
- dna sequences
- sequences coding
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3007—Carcino-embryonic Antigens
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Oncology (AREA)
- Cell Biology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US16585688A | 1988-03-09 | 1988-03-09 | |
US27257788A | 1988-11-17 | 1988-11-17 |
Publications (2)
Publication Number | Publication Date |
---|---|
DK108589D0 true DK108589D0 (da) | 1989-03-07 |
DK108589A DK108589A (da) | 1989-09-22 |
Family
ID=26861757
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK108589A DK108589A (da) | 1988-03-09 | 1989-03-07 | Chimere antistoffer rettet mod humant carcinoembryonalt antigen samt dna-sekvenser, der koder for saadanne antistoffer |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0332424A3 (da) |
JP (1) | JPH029371A (da) |
AU (1) | AU618990B2 (da) |
DK (1) | DK108589A (da) |
IL (1) | IL89489A0 (da) |
Families Citing this family (50)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8800077D0 (en) * | 1988-01-05 | 1988-02-10 | Ciba Geigy Ag | Novel chimeric antibodies |
US5843708A (en) * | 1988-01-05 | 1998-12-01 | Ciba-Geigy Corporation | Chimeric antibodies |
IL89491A0 (en) * | 1988-11-17 | 1989-09-10 | Hybritech Inc | Bifunctional chimeric antibodies |
US5081235A (en) * | 1989-07-26 | 1992-01-14 | City Of Hope | Chimeric anti-cea antibody |
AU634314B2 (en) * | 1989-11-13 | 1993-02-18 | Green Cross Corporation, The | Chimeric mouse-human a10 antibody with specificity to a human tumor cell antigen |
GB2276169A (en) * | 1990-07-05 | 1994-09-21 | Celltech Ltd | Antibodies specific for carcinoembryonic antigen |
US6797492B2 (en) | 1991-05-17 | 2004-09-28 | Merck & Co., Inc. | Method for reducing the immunogenicity of antibody variable domains |
ATE171472T1 (de) * | 1992-02-19 | 1998-10-15 | Schering Corp | Klonierung und expression von humanisierten monoklonalen antikörpern gegen menschliches interleukin-4 |
US5472693A (en) * | 1993-02-16 | 1995-12-05 | The Dow Chemical Company | Family of anti-carcinoembryonic antigen chimeric antibodies |
CU22615A1 (es) | 1994-06-30 | 2000-02-10 | Centro Inmunologia Molecular | Procedimiento de obtención de anticuerpos monoclonales murinos menos inmunogénicos. anticuerpos monoclonales obtenidos |
US6380979B1 (en) * | 1996-07-02 | 2002-04-30 | Matsushita Electric Industrial Co., Ltd. | Scanning line converting circuit and interpolation coefficient generating circuit |
JP2003520195A (ja) | 1999-05-14 | 2003-07-02 | イムクローン システムズ インコーポレイティド | 上皮成長因子受容体アンタゴニストによる難治性ヒト腫瘍の処理 |
US7740841B1 (en) | 2000-01-28 | 2010-06-22 | Sunnybrook Health Science Center | Therapeutic method for reducing angiogenesis |
IL152825A (en) | 2000-05-16 | 2009-07-20 | Univ Jefferson | Rabies virus-specific neutralizing human monoclonal antibodies and nucleic acids and related methods |
US7071319B2 (en) | 2000-05-16 | 2006-07-04 | Thomas Jefferson University | Recombinant antibodies, and compositions and methods for making and using the same |
DK2308507T3 (da) | 2002-07-19 | 2015-04-20 | Beth Israel Hospital | Fremgangsmåder til behandling af præeklampsi |
US7435419B2 (en) | 2002-07-19 | 2008-10-14 | Beth Israel Deaconess Medical Center | Methods of diagnosing and treating pre-eclampsia or eclampsia |
WO2005016970A2 (en) | 2003-05-01 | 2005-02-24 | Imclone Systems Incorporated | Fully human antibodies directed against the human insulin-like growth factor-1 receptor |
CA2560305C (en) | 2004-03-19 | 2016-07-05 | Imclone Systems Incorporated | Human anti-epidermal growth factor receptor antibody |
DK1784220T3 (da) | 2004-08-26 | 2018-03-19 | Univ Western Ontario | Bakterielle mål til opnåelse af jern |
CA2581336C (en) | 2004-09-24 | 2022-10-04 | S. Ananth Karumanchi | Diagnosis of pregnancy-related hypertensive disorder by measurement of soluble endoglin |
CN102397542B (zh) | 2004-11-18 | 2014-05-07 | 英克隆有限责任公司 | 抗血管内皮生长因子受体-1的抗体 |
EP1812064A4 (en) | 2004-11-19 | 2009-07-08 | Cornell Res Foundation Inc | USE OF ENDOTHELIAL VASCULAR GROWTH FACTOR RECEPTOR CELLS IN THE TREATMENT AND MONITORING OF CANCER AND IN THE SCREENING OF CHEMOTHERAPEUTIC AGENTS |
BRPI0611984A2 (pt) | 2005-06-17 | 2009-07-07 | Imclone Systems Inc | uso de anticorpos igf-ir para fabricação de um medicamento para tratar um tumor ósseo |
BRPI0617057A2 (pt) | 2005-08-30 | 2011-07-12 | Univ Miami | anticorpo isolado, toxina especìfica para receptor de fator de necrose tumoral 25 (tnfr25), método para ativar o receptor de fator de necrose tumoral 25 (tnfr25), método para inibir a sinalização do receptor de fator de necrose tumoral 25 (tnfr25) numa célula, vacina antitumoral, método para imunizar um paciente contra tumor, método para tratar cáncer num paciente, método para tratar e/ou prevenir inflamação intestinal, composição terapêutica para a facilitação de um transplante de órgão, método para transplantar um tecido de um doador para um hospedeiro, método para inibir a expressão clonal de uma população de células t cd8 cognatas, método para tratar e/ou prevenir inflamação pulmonar, antagonista de tnfr25 isolado, composição e vetor de expressão |
AU2007274738B2 (en) | 2006-07-18 | 2013-11-28 | Sanofi-Aventis | Antagonist antibody against EphA2 for the treatment of cancer |
EP1914242A1 (en) | 2006-10-19 | 2008-04-23 | Sanofi-Aventis | Novel anti-CD38 antibodies for the treatment of cancer |
KR100883430B1 (ko) | 2007-06-13 | 2009-02-12 | 한국생명공학연구원 | 혈관내피성장인자 수용체를 중화하는 인간 단클론항체 및그 용도 |
UA117446C2 (uk) | 2007-08-29 | 2018-08-10 | Санофі-Авентіс | Гуманізоване антитіло до cxcr5 |
EP2050764A1 (en) | 2007-10-15 | 2009-04-22 | sanofi-aventis | Novel polyvalent bispecific antibody format and uses thereof |
AU2009222998B2 (en) | 2008-03-12 | 2013-05-23 | Imclone Llc | Anti-TYRP1 antibodies |
US8163497B2 (en) | 2008-09-07 | 2012-04-24 | Glyconex Inc. | Anti-extended type I glycosphingolipid antibody, derivatives thereof and use |
WO2011022472A2 (en) | 2009-08-18 | 2011-02-24 | President And Fellows Of Harvard College | Methods and compositions for the treatment of proliferative and pathogenic diseases |
UY32914A (es) | 2009-10-02 | 2011-04-29 | Sanofi Aventis | Anticuerpos que se usan específicamente al receptor epha2 |
WO2011062560A1 (en) * | 2009-11-19 | 2011-05-26 | National University Of Singapore | Method for producing t cell receptor-like monoclonal antibodies and uses thereof |
MX341687B (es) | 2010-02-10 | 2016-08-30 | Immunogen Inc | "anticuerpos cd20 y su utilización". |
CN102844050B (zh) | 2010-02-19 | 2019-02-05 | 康奈尔大学 | 自身免疫性脱髓鞘疾病及其它自身免疫疾病或炎性疾病的治疗方法 |
AR080698A1 (es) | 2010-04-01 | 2012-05-02 | Imclone Llc | Anticuerpo o fragmento del mismo que especificamente enlaza la variante de csf -1r humano, composicion farmaceutica que lo comprende, su uso para la manufactura de un medicamento util para el tratamiento de cancer y metodo para determinar si un sujeto es candidato para tratamiento de cancer basado e |
WO2011145085A2 (en) | 2010-05-21 | 2011-11-24 | Procognia (Israel) Ltd | Novel antibodies and methods of use for the treatment and diagnosis of cancer |
EP3252076B1 (en) | 2011-01-14 | 2019-09-04 | The Regents Of The University Of California | Diagnostic use of antibodies against ror-1 protein |
EP3235508B1 (en) | 2011-03-16 | 2020-12-30 | Sanofi | Compositions comprising a dual v region antibody-like protein |
US9592289B2 (en) | 2012-03-26 | 2017-03-14 | Sanofi | Stable IgG4 based binding agent formulations |
TW201628647A (zh) | 2014-06-27 | 2016-08-16 | 賽諾菲公司 | 抗-il4-il13雙特異性抗體 |
DE202014008375U1 (de) | 2014-10-18 | 2015-10-21 | Reinz-Dichtungs-Gmbh | Seperatorplatte und elektrochemisches System |
US20180230218A1 (en) | 2017-01-04 | 2018-08-16 | Immunogen, Inc. | Met antibodies and immunoconjugates and uses thereof |
TWI808963B (zh) | 2017-03-22 | 2023-07-21 | 法商賽諾菲公司 | 使用人類化抗cxcr5抗體治療狼瘡 |
WO2019207159A1 (en) | 2018-04-27 | 2019-10-31 | Fondazione Ebri Rita Levi-Montalcini | Antibody directed against a tau-derived neurotoxic peptide and uses thereof |
WO2019217450A1 (en) | 2018-05-08 | 2019-11-14 | Rhode Island Hospital | Anti-chi3l1 antibodies for the detection and/or treatment of nonalcoholic fattly liver disease/nonalcoholic steatohepatitis and subsequent complications |
WO2020014306A1 (en) | 2018-07-10 | 2020-01-16 | Immunogen, Inc. | Met antibodies and immunoconjugates and uses thereof |
US11827671B2 (en) | 2019-05-24 | 2023-11-28 | Sanofi | Methods for treating systemic sclerosis |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4816567A (en) * | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
IL89490A0 (en) * | 1988-11-17 | 1989-09-10 | Hybritech Inc | Chimeric antibodies directed against metal chelates |
IL89491A0 (en) * | 1988-11-17 | 1989-09-10 | Hybritech Inc | Bifunctional chimeric antibodies |
-
1989
- 1989-03-06 IL IL89489A patent/IL89489A0/xx unknown
- 1989-03-07 DK DK108589A patent/DK108589A/da not_active Application Discontinuation
- 1989-03-07 AU AU31072/89A patent/AU618990B2/en not_active Ceased
- 1989-03-08 JP JP1057673A patent/JPH029371A/ja active Pending
- 1989-03-08 EP EP19890302312 patent/EP0332424A3/en not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
AU618990B2 (en) | 1992-01-16 |
AU3107289A (en) | 1989-09-14 |
JPH029371A (ja) | 1990-01-12 |
IL89489A0 (en) | 1989-09-10 |
DK108589A (da) | 1989-09-22 |
EP0332424A3 (en) | 1991-07-03 |
EP0332424A2 (en) | 1989-09-13 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
AHB | Application shelved due to non-payment |