DK1035133T3 - Fusionsproteiner, der omfatter bærere, som kan inducere et dobbelt immunrespons - Google Patents
Fusionsproteiner, der omfatter bærere, som kan inducere et dobbelt immunresponsInfo
- Publication number
- DK1035133T3 DK1035133T3 DK00301103T DK00301103T DK1035133T3 DK 1035133 T3 DK1035133 T3 DK 1035133T3 DK 00301103 T DK00301103 T DK 00301103T DK 00301103 T DK00301103 T DK 00301103T DK 1035133 T3 DK1035133 T3 DK 1035133T3
- Authority
- DK
- Denmark
- Prior art keywords
- vertebrate
- immune response
- fusion protein
- fusion proteins
- peptide
- Prior art date
Links
- 102000037865 fusion proteins Human genes 0.000 title abstract 7
- 108020001507 fusion proteins Proteins 0.000 title abstract 7
- 230000028993 immune response Effects 0.000 title abstract 3
- 230000009977 dual effect Effects 0.000 title abstract 2
- 239000000969 carrier Substances 0.000 title 1
- 241000251539 Vertebrata <Metazoa> Species 0.000 abstract 10
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 4
- 230000000694 effects Effects 0.000 abstract 3
- 244000052769 pathogen Species 0.000 abstract 3
- 230000001717 pathogenic effect Effects 0.000 abstract 3
- 230000004044 response Effects 0.000 abstract 2
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 210000000987 immune system Anatomy 0.000 abstract 1
- 230000002163 immunogen Effects 0.000 abstract 1
- 230000003259 immunoinhibitory effect Effects 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0006—Contraceptive vaccins; Vaccines against sex hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/26—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against hormones ; against hormone releasing or inhibiting factors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/23—Luteinising hormone-releasing hormone [LHRH]; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16711—Varicellovirus, e.g. human herpesvirus 3, Varicella Zoster, pseudorabies
- C12N2710/16722—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Virology (AREA)
- Immunology (AREA)
- Endocrinology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Reproductive Health (AREA)
- Microbiology (AREA)
- Communicable Diseases (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US12045499P | 1999-02-17 | 1999-02-17 | |
EP00301103A EP1035133B1 (en) | 1999-02-17 | 2000-02-14 | Fusion proteins comprising carriers that can induce a dual immune response |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1035133T3 true DK1035133T3 (da) | 2005-05-02 |
Family
ID=22390397
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK00301103T DK1035133T3 (da) | 1999-02-17 | 2000-02-14 | Fusionsproteiner, der omfatter bærere, som kan inducere et dobbelt immunrespons |
Country Status (10)
Country | Link |
---|---|
US (2) | US6911206B1 (da) |
EP (1) | EP1035133B1 (da) |
JP (1) | JP2000236887A (da) |
AT (1) | ATE286511T1 (da) |
BR (1) | BR0000489A (da) |
CA (1) | CA2297441A1 (da) |
DE (1) | DE60017211T2 (da) |
DK (1) | DK1035133T3 (da) |
ES (1) | ES2233284T3 (da) |
PT (1) | PT1035133E (da) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PT1035133E (pt) * | 1999-02-17 | 2005-05-31 | Pfizer Prod Inc | Proteinas de fusao compreendendo veiculos que podem induzir uma dupla resposta imune |
GB9919409D0 (en) * | 1999-08-18 | 1999-10-20 | Univ Oxford Brookes | Baculovirus expression system |
WO2004105791A2 (en) * | 2003-06-02 | 2004-12-09 | The Talwar Research Foundation | Recombinant anti-lhrh vaccines |
RU2347586C2 (ru) * | 2004-04-05 | 2009-02-27 | Пфайзер Продактс Инк. | Микрофлюидизированные эмульсии типа "масло в воде" и вакцинные композиции |
US8524247B2 (en) | 2008-09-17 | 2013-09-03 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services, Centers For Disease Control And Prevention | Rabies virus-based recombinant immunocontraceptive compositions and methods of use |
CU23739A1 (es) | 2008-09-30 | 2011-12-28 | Ct Ingenieria Genetica Biotech | Composición farmacéutica utilizando combinaciones de variantes de la hormona liberadora de las gonadotropinas (gnrh) como inmunógeno |
KR101145911B1 (ko) | 2008-12-22 | 2012-05-15 | 한국화학연구원 | 대장균의 외막단백질 OmpW를 이용한 목적단백질의 표면발현 방법 |
US11408899B2 (en) * | 2013-07-12 | 2022-08-09 | The Children's Hospital Of Philadelphia | AAV vector and assay for anti-AAV (adeno-associated virus) neutralizing antibodies |
CN113517025B (zh) * | 2020-04-10 | 2022-03-18 | 西咸新区予果微码生物科技有限公司 | 一种病原体在线监测***及方法 |
CN112979789B (zh) * | 2021-04-14 | 2021-07-27 | 北京市农林科学院 | 用于检测牛传染性鼻气管炎病毒的中和抗体的阻断elisa试剂盒及其应用 |
Family Cites Families (45)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3137631A (en) | 1959-12-01 | 1964-06-16 | Faberge Inc | Encapsulation in natural products |
US3959457A (en) | 1970-06-05 | 1976-05-25 | Temple University | Microparticulate material and method of making such material |
JPS5186117A (en) | 1975-01-27 | 1976-07-28 | Tanabe Seiyaku Co | Johoseibiryushiseizainoseiho |
US4205060A (en) | 1978-12-20 | 1980-05-27 | Pennwalt Corporation | Microcapsules containing medicament-polymer salt having a water-insoluble polymer sheath, their production and their use |
US4452747A (en) | 1982-03-22 | 1984-06-05 | Klaus Gersonde | Method of and arrangement for producing lipid vesicles |
GB2140810B (en) | 1983-05-24 | 1987-07-08 | Celltech Ltd | Polypeptide and protein products, and process for their production |
GB8314362D0 (en) | 1983-05-24 | 1983-06-29 | Celltech Ltd | Polypeptide and protein products |
US4744933A (en) | 1984-02-15 | 1988-05-17 | Massachusetts Institute Of Technology | Process for encapsulation and encapsulated active material system |
US5008050A (en) | 1984-06-20 | 1991-04-16 | The Liposome Company, Inc. | Extrusion technique for producing unilamellar vesicles |
US5672347A (en) | 1984-07-05 | 1997-09-30 | Genentech, Inc. | Tumor necrosis factor antagonists and their use |
US4722840A (en) | 1984-09-12 | 1988-02-02 | Chiron Corporation | Hybrid particle immunogens |
EP0175261B1 (en) | 1984-09-12 | 1991-12-11 | Chiron Corporation | Hybrid particle immunogens |
US4921706A (en) | 1984-11-20 | 1990-05-01 | Massachusetts Institute Of Technology | Unilamellar lipid vesicles and method for their formation |
US4606940A (en) | 1984-12-21 | 1986-08-19 | The Ohio State University Research Foundation | Small particle formation and encapsulation |
IL78775A (en) | 1985-05-15 | 1992-06-21 | Biotech Australia Pty Ltd | Oral vaccines |
US5089396A (en) | 1985-10-03 | 1992-02-18 | Genentech, Inc. | Nucleic acid encoding β chain prodomains of inhibin and method for synthesizing polypeptides using such nucleic acid |
US5009956A (en) | 1987-02-24 | 1991-04-23 | Univ Minnesota | Phospholipase A2-resistant liposomes |
US4975420A (en) | 1987-09-30 | 1990-12-04 | University Of Saskatchewan | Agents and procedures for provoking an immune response to GnRH and immuno sterilizing mammals |
JPH01171489A (ja) | 1987-12-26 | 1989-07-06 | Chemo Sero Therapeut Res Inst | 狂犬病ウイルス糖蛋白質をコードする遺伝子断片およびこれを用いた狂犬病ウイルス糖蛋白質の製法 |
US5585264A (en) * | 1988-07-15 | 1996-12-17 | University Of Saskatchewan | Nucleotide sequences encoding recombinant bovine herpesvirus type-1 GI, GIII and GIV polypeptides |
US5151267A (en) | 1988-07-15 | 1992-09-29 | University Of Saskatchewan | Bovine herpesvirus type 1 polypeptides and vaccines |
IL91462A0 (en) * | 1988-08-30 | 1990-04-29 | Applied Research Systems | Recombinant fusion proteins and dna encoding for such a protein |
US4927637A (en) | 1989-01-17 | 1990-05-22 | Liposome Technology, Inc. | Liposome extrusion method |
US4944948A (en) | 1989-02-24 | 1990-07-31 | Liposome Technology, Inc. | EGF/Liposome gel composition and method |
CA2040441C (en) * | 1989-08-25 | 1998-03-31 | Gregory J. Russell-Jones | Fusion proteins |
US5132117A (en) | 1990-01-11 | 1992-07-21 | Temple University | Aqueous core microcapsules and method for their preparation |
GB9007416D0 (en) | 1990-04-02 | 1990-05-30 | Wellcome Found | Expression of heterologous protein in yeast |
US5238823A (en) | 1990-08-22 | 1993-08-24 | Veterinary Infectious Disease Organization | Interleukin-2-leukotoxin gene fusions and uses thereof |
DE69121877T2 (de) | 1991-02-01 | 1997-04-03 | Bmra Corp Bv | Verfahren zur Messung der Aktivität angiotensinkonvertierenden Enzyms in biologischen Proben |
US5422110A (en) * | 1991-10-16 | 1995-06-06 | University Of Saskatchewan | Enhanced immunogenicity using leukotoxin chimeras |
GB9201013D0 (en) | 1992-01-17 | 1992-03-11 | Animal Health Inst | Vaccines |
US5612360A (en) | 1992-06-03 | 1997-03-18 | Eli Lilly And Company | Angiotensin II antagonists |
ZA934199B (en) * | 1992-06-18 | 1994-01-10 | Akzo Nv | Carrier system against gnrh |
US5441736A (en) | 1992-11-05 | 1995-08-15 | University Of Saskatchewan | Actinobacillus pleuropneumoniae outer membrane lipoprotein A and uses thereof |
WO1994024296A2 (en) | 1993-04-19 | 1994-10-27 | University Of Saskatchewan | Recombinant bovine herpesvirus type 1 vaccines |
US5545523A (en) | 1993-05-28 | 1996-08-13 | Cornell Research Foundation, Inc. | Methods of detecting bovine herpesvirus 1 (BHV-1) in semen by nucleic acid amplification |
JP2577304B2 (ja) | 1993-07-23 | 1997-01-29 | 大日本製薬株式会社 | ヒト インターロイキン1活性を有するポリペプチド |
US5599663A (en) | 1993-08-27 | 1997-02-04 | Brighan & Women's Hospital | Angiotensin IV and analogs as regulators of fibrinolysis |
PT730465E (pt) | 1993-09-24 | 2002-06-28 | Univ Southern California | Utilizacao de angiotensina iii e de analogos desta em cicatrizacao de tecidos |
US5786179A (en) | 1994-02-28 | 1998-07-28 | Agritech Technologies Ltd. | Heterologous protein comprising avian alpha-subunit inhibin protein and methods of producing same |
DE69530227T2 (de) | 1994-04-15 | 2004-04-01 | Temple University | Methode zum einkapseln mittels eines wässrigen lösungsmittels und mikrokapseln |
IL112581A0 (en) | 1995-02-08 | 1995-05-26 | Moreh Ronen | Pop rivet |
US6017735A (en) * | 1997-01-23 | 2000-01-25 | Marie Curie Cancer Care | Materials and methods for intracellular transport and their uses |
AUPO776897A0 (en) | 1997-07-09 | 1997-07-31 | Csl Limited | A method of achieving production gains in livestock and agents useful for same |
PT1035133E (pt) * | 1999-02-17 | 2005-05-31 | Pfizer Prod Inc | Proteinas de fusao compreendendo veiculos que podem induzir uma dupla resposta imune |
-
2000
- 2000-02-14 PT PT00301103T patent/PT1035133E/pt unknown
- 2000-02-14 AT AT00301103T patent/ATE286511T1/de not_active IP Right Cessation
- 2000-02-14 ES ES00301103T patent/ES2233284T3/es not_active Expired - Lifetime
- 2000-02-14 DK DK00301103T patent/DK1035133T3/da active
- 2000-02-14 DE DE60017211T patent/DE60017211T2/de not_active Expired - Fee Related
- 2000-02-14 EP EP00301103A patent/EP1035133B1/en not_active Expired - Lifetime
- 2000-02-16 US US09/506,078 patent/US6911206B1/en not_active Expired - Fee Related
- 2000-02-17 JP JP2000039532A patent/JP2000236887A/ja active Pending
- 2000-02-17 BR BR0000489-8A patent/BR0000489A/pt not_active IP Right Cessation
- 2000-02-17 CA CA002297441A patent/CA2297441A1/en not_active Abandoned
-
2004
- 2004-11-29 US US10/999,363 patent/US20050095258A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP1035133A3 (en) | 2002-09-25 |
ES2233284T3 (es) | 2005-06-16 |
PT1035133E (pt) | 2005-05-31 |
DE60017211D1 (de) | 2005-02-10 |
US20050095258A1 (en) | 2005-05-05 |
EP1035133B1 (en) | 2005-01-05 |
EP1035133A2 (en) | 2000-09-13 |
JP2000236887A (ja) | 2000-09-05 |
CA2297441A1 (en) | 2000-08-17 |
DE60017211T2 (de) | 2005-06-02 |
ATE286511T1 (de) | 2005-01-15 |
BR0000489A (pt) | 2001-05-02 |
US6911206B1 (en) | 2005-06-28 |
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