DK1015419T3 - Polydentate iminer og deres metalkomplekser - Google Patents

Polydentate iminer og deres metalkomplekser

Info

Publication number
DK1015419T3
DK1015419T3 DK98910837T DK98910837T DK1015419T3 DK 1015419 T3 DK1015419 T3 DK 1015419T3 DK 98910837 T DK98910837 T DK 98910837T DK 98910837 T DK98910837 T DK 98910837T DK 1015419 T3 DK1015419 T3 DK 1015419T3
Authority
DK
Denmark
Prior art keywords
polydentate
imines
metal complexes
complexes
metal
Prior art date
Application number
DK98910837T
Other languages
English (en)
Inventor
Martin Schroder
Daniel Martin John Doble
Original Assignee
Amersham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amersham Plc filed Critical Amersham Plc
Priority claimed from PCT/GB1998/000678 external-priority patent/WO1998039288A1/en
Application granted granted Critical
Publication of DK1015419T3 publication Critical patent/DK1015419T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6515Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having three nitrogen atoms as the only ring hetero atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/06Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C251/00Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C251/02Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups
    • C07C251/04Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups having carbon atoms of imino groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C251/06Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups having carbon atoms of imino groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of a saturated carbon skeleton
    • C07C251/08Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups having carbon atoms of imino groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of a saturated carbon skeleton being acyclic
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C251/00Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C251/02Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups
    • C07C251/24Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups having carbon atoms of imino groups bound to carbon atoms of six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/38Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/3804Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
    • C07F9/3808Acyclic saturated acids which can have further substituents on alkyl

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Enzymes And Modification Thereof (AREA)
DK98910837T 1997-03-07 1998-03-06 Polydentate iminer og deres metalkomplekser DK1015419T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP97301548 1997-03-07
PCT/GB1998/000678 WO1998039288A1 (en) 1997-03-07 1998-03-06 Polydentate imines and their metal complexes

Publications (1)

Publication Number Publication Date
DK1015419T3 true DK1015419T3 (da) 2003-04-22

Family

ID=8229239

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98910837T DK1015419T3 (da) 1997-03-07 1998-03-06 Polydentate iminer og deres metalkomplekser

Country Status (6)

Country Link
US (1) US6153775A (da)
JP (1) JP4056088B2 (da)
DE (1) DE69810492T2 (da)
DK (1) DK1015419T3 (da)
ES (1) ES2190067T3 (da)
NO (1) NO313187B1 (da)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020094316A1 (en) * 2001-01-09 2002-07-18 Shuang Liu Polypodal chelants for metallopharmaceuticals
WO2002101847A2 (en) * 2001-06-12 2002-12-19 University Of Florida Method and device for producing near-infrared radiation
BRPI0512235A (pt) 2004-06-18 2008-02-19 Ambrx Inc polipeptìdeos ligadores de antìgenos e seus usos
JP4930943B2 (ja) * 2007-05-11 2012-05-16 国立大学法人群馬大学 酸素濃度測定試薬および酸素濃度測定方法
EP2192922A4 (en) 2007-09-17 2010-09-29 Univ California INTERNALIZING HUMAN MONOCLONAL ANTIBODIES TARGING PROSTATE <I> IN SITU CANCER CELLS </ I>
CN103518135B (zh) 2011-03-11 2016-08-17 内布拉斯加大学董事委员会 冠状动脉疾病的生物标志物
WO2017095823A1 (en) 2015-11-30 2017-06-08 The Regents Of The University Of California Tumor-specific payload delivery and immune activation using a human antibody targeting a highly specific tumor cell surface antigen
CN116419747A (zh) 2020-08-07 2023-07-11 福蒂斯治疗公司 靶向cd46的免疫偶联物及其使用方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5071965A (en) * 1988-07-19 1991-12-10 Mallinckrodt Medical, Inc. Novel tc-99m complexes
FR2670113A1 (fr) * 1990-12-06 1992-06-12 Medgenix Group Sa Agent de contraste constitue par un complexe neutre d'un cation paramagnetique et ligand pour former un complexe.
US5405601A (en) * 1993-07-02 1995-04-11 Mallinckrodt Medical Inc. Functionalized tripodal ligands for imaging applications
DE4406465A1 (de) * 1994-02-23 1995-08-24 Univ Leipzig Kontrastmittel für die Kernspintomographie

Also Published As

Publication number Publication date
US6153775A (en) 2000-11-28
JP2001514624A (ja) 2001-09-11
DE69810492D1 (de) 2003-02-06
DE69810492T2 (de) 2003-11-20
ES2190067T3 (es) 2003-07-16
NO994265L (no) 1999-11-05
NO994265D0 (no) 1999-09-02
JP4056088B2 (ja) 2008-03-05
NO313187B1 (no) 2002-08-26

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