DK1013639T3 - Arylcarboxylsyre og tetrazolderivater, som indeholder en carbamoyloxyenhed - Google Patents

Arylcarboxylsyre og tetrazolderivater, som indeholder en carbamoyloxyenhed

Info

Publication number
DK1013639T3
DK1013639T3 DK99125027T DK99125027T DK1013639T3 DK 1013639 T3 DK1013639 T3 DK 1013639T3 DK 99125027 T DK99125027 T DK 99125027T DK 99125027 T DK99125027 T DK 99125027T DK 1013639 T3 DK1013639 T3 DK 1013639T3
Authority
DK
Denmark
Prior art keywords
carbamoyloxy
unit
carboxylic acid
derivatives containing
aryl carboxylic
Prior art date
Application number
DK99125027T
Other languages
English (en)
Inventor
Francisco Javier Lopez-Tapia
Alexander Victor Muehldorf
Counde O'yang
Daniel Lee Severance
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of DK1013639T3 publication Critical patent/DK1013639T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04—Five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/26—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atom of at least one of the carbamate groups bound to a carbon atom of a six-membered aromatic ring
    • C07C271/28—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atom of at least one of the carbamate groups bound to a carbon atom of a six-membered aromatic ring to a carbon atom of a non-condensed six-membered aromatic ring

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Vascular Medicine (AREA)
  • Gynecology & Obstetrics (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
DK99125027T 1998-12-23 1999-12-15 Arylcarboxylsyre og tetrazolderivater, som indeholder en carbamoyloxyenhed DK1013639T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11344698P 1998-12-23 1998-12-23
US15181499P 1999-08-30 1999-08-30

Publications (1)

Publication Number Publication Date
DK1013639T3 true DK1013639T3 (da) 2004-02-09

Family

ID=26811078

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99125027T DK1013639T3 (da) 1998-12-23 1999-12-15 Arylcarboxylsyre og tetrazolderivater, som indeholder en carbamoyloxyenhed

Country Status (29)

Country Link
US (1) US6335459B1 (da)
EP (1) EP1013639B1 (da)
JP (1) JP3415085B2 (da)
KR (1) KR100378335B1 (da)
CN (1) CN1167670C (da)
AR (1) AR029320A1 (da)
AT (1) ATE251125T1 (da)
AU (1) AU735640B2 (da)
BR (1) BR9905974A (da)
CA (1) CA2292921C (da)
DE (1) DE69911726T2 (da)
DK (1) DK1013639T3 (da)
ES (1) ES2207108T3 (da)
HR (1) HRP990394A2 (da)
HU (1) HUP9904659A3 (da)
ID (1) ID25983A (da)
IL (1) IL133578A (da)
MA (1) MA26713A1 (da)
NO (1) NO316171B1 (da)
NZ (1) NZ501891A (da)
PE (1) PE20001368A1 (da)
PL (1) PL337419A1 (da)
PT (1) PT1013639E (da)
RU (1) RU2179969C2 (da)
SG (1) SG90086A1 (da)
TR (1) TR199903310A2 (da)
TW (1) TWI221834B (da)
UY (1) UY25876A1 (da)
YU (1) YU69699A (da)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9828442D0 (en) 1998-12-24 1999-02-17 Karobio Ab Novel thyroid receptor ligands and method II
SE0100158D0 (sv) * 2001-01-19 2001-01-19 Synphora Ab Novel method and composition for local treatment of Meniere´s disease and tinnitus
WO2002070514A1 (en) * 2001-03-02 2002-09-12 F. Hoffmann-La Roche Ag Alkoxycarbonylamino heteroaryl carboxylic acid derivatives as ip antagonists
US20060217421A1 (en) 2003-05-09 2006-09-28 Hajimu Kurumatani Fortifier
UA93548C2 (uk) 2006-05-05 2011-02-25 Айерем Елелсі Сполуки та композиції як модулятори хеджхогівського сигнального шляху
US9669381B2 (en) 2007-06-27 2017-06-06 Hrd Corporation System and process for hydrocracking
NZ587693A (en) 2008-03-18 2012-07-27 Arena Pharm Inc Modulators of the prostacyclin (PGI2) receptor useful for the treatment of disorders related thereto
KR101587071B1 (ko) * 2008-07-23 2016-01-20 도레이 카부시키가이샤 만성 신부전 처치제
AU2011263417B2 (en) 2010-06-11 2014-03-27 Rhodes Technologies Transition metal-catalyzed processes for the preparation of N-allyl compounds and use thereof
AU2011263416B2 (en) 2010-06-11 2014-04-10 Rhodes Technologies Process for N-dealkylation of tertiary amines
CN110582271B (zh) 2017-03-01 2022-06-14 阿瑞那制药公司 包含pgi2受体激动剂的组合物及其制备方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1079414A (en) 1965-06-30 1967-08-16 Smith & Nephew Derivatives of acetic acid and a process for their preparation
GB1185539A (en) 1967-11-03 1970-03-25 Smith & Nephew Substituted Tetrazoles
DE2432560A1 (de) 1974-07-06 1976-01-22 Boehringer Mannheim Gmbh Neue phenoxyalkylcarbonsaeurederivate und verfahren zur herstellung derselben
JPS5832859A (ja) 1981-08-20 1983-02-25 Dainippon Pharmaceut Co Ltd Ｎ，ｎ−ジメチルカルバミン酸ベンジルエステル誘導体
JPH0725725B2 (ja) 1987-07-23 1995-03-22 保土谷化学工業株式会社 ベンズアミド誘導体
US5084466A (en) 1989-01-31 1992-01-28 Hoffmann-La Roche Inc. Novel carboxamide pyridine compounds which have useful pharmaceutical utility
CA2090283A1 (en) 1992-02-28 1993-08-29 Nobuyuki Hamanaka Phenoxyacetic acid derivatives
CA2183063A1 (en) 1994-02-10 1995-08-17 Atsushi Ichikawa Prostaglandin i2 receptor
HU224822B1 (en) 1994-03-10 2006-02-28 Fujisawa Pharmaceutical Co Naphthalene derivatives as prostaglandin i2 agonists, pharmaceutical compns. contg. them and process for preparing them
US5753700A (en) 1994-12-28 1998-05-19 Ono Pharmaceutical Co., Ltd. Naphthyloxyacetic acid derivatives
TW401408B (en) 1995-07-21 2000-08-11 Fujisawa Pharmaceutical Co Heterocyclic compounds having prostaglandin I2 agonism
WO1997005091A1 (fr) 1995-07-26 1997-02-13 Ono Pharmaceutical Co., Ltd. Derives d'acide naphtyloxyacetique et medicaments integrant ces derives comme principes actifs
AUPP029197A0 (en) 1997-11-10 1997-12-04 Fujisawa Pharmaceutical Co., Ltd. Benzocycloheptene derivatives
AUPP109097A0 (en) 1997-12-22 1998-01-22 Fujisawa Pharmaceutical Co., Ltd. Napthalene derivatives

Also Published As

Publication number Publication date
IL133578A (en) 2004-07-25
RU2179969C2 (ru) 2002-02-27
ID25983A (id) 2000-11-16
HRP990394A2 (en) 2000-08-31
CA2292921C (en) 2004-08-17
NO996366L (no) 2000-06-26
TR199903310A3 (tr) 2000-10-23
DE69911726T2 (de) 2004-07-29
AU6534099A (en) 2000-07-06
TR199903310A2 (xx) 2000-10-23
NZ501891A (en) 2001-10-26
IL133578A0 (en) 2001-04-30
HUP9904659A3 (en) 2000-12-28
JP2000191523A (ja) 2000-07-11
UY25876A1 (es) 2001-07-31
ES2207108T3 (es) 2004-05-16
PL337419A1 (en) 2000-07-03
US6335459B1 (en) 2002-01-01
JP3415085B2 (ja) 2003-06-09
MA26713A1 (fr) 2004-12-20
ATE251125T1 (de) 2003-10-15
SG90086A1 (en) 2002-07-23
HU9904659D0 (en) 2000-02-28
KR20000048322A (ko) 2000-07-25
AR029320A1 (es) 2003-06-25
YU69699A (sh) 2001-12-26
DE69911726D1 (de) 2003-11-06
EP1013639A1 (en) 2000-06-28
NO316171B1 (no) 2003-12-22
AU735640B2 (en) 2001-07-12
KR100378335B1 (ko) 2003-03-29
TWI221834B (en) 2004-10-11
EP1013639B1 (en) 2003-10-01
CN1167670C (zh) 2004-09-22
PE20001368A1 (es) 2000-12-14
CA2292921A1 (en) 2000-06-23
NO996366D0 (no) 1999-12-21
BR9905974A (pt) 2000-09-12
CN1266054A (zh) 2000-09-13
HUP9904659A2 (hu) 2000-11-28
PT1013639E (pt) 2004-02-27

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