DK0998288T4 - Sammensætninger indeholdende kapasaicin eller kapsaicinanaloge og et lokalbedövelsesmiddel - Google Patents

Sammensætninger indeholdende kapasaicin eller kapsaicinanaloge og et lokalbedövelsesmiddel

Info

Publication number
DK0998288T4
DK0998288T4 DK98911614T DK98911614T DK0998288T4 DK 0998288 T4 DK0998288 T4 DK 0998288T4 DK 98911614 T DK98911614 T DK 98911614T DK 98911614 T DK98911614 T DK 98911614T DK 0998288 T4 DK0998288 T4 DK 0998288T4
Authority
DK
Denmark
Prior art keywords
capsaicin
site
anesthesia
pain
analogues
Prior art date
Application number
DK98911614T
Other languages
English (en)
Other versions
DK0998288T3 (da
Inventor
James N Campbell
Marco Pappagallo
Richard A Meyer
Original Assignee
James N Campbell
Richard A Meyer
Marco Pappagallo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21912426&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0998288(T4) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by James N Campbell, Richard A Meyer, Marco Pappagallo filed Critical James N Campbell
Publication of DK0998288T3 publication Critical patent/DK0998288T3/da
Application granted granted Critical
Publication of DK0998288T4 publication Critical patent/DK0998288T4/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A61K31/24—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
    • A61K31/245—Amino benzoic acid types, e.g. procaine, novocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A61P23/02—Local anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
DK98911614T 1997-03-13 1998-03-12 Sammensætninger indeholdende kapasaicin eller kapsaicinanaloge og et lokalbedövelsesmiddel DK0998288T4 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US4069797P 1997-03-13 1997-03-13
PCT/US1998/004912 WO1998040070A1 (en) 1997-03-13 1998-03-12 Compositions containing capsaicin or capsaicin analogues and a local anesthetic

Publications (2)

Publication Number Publication Date
DK0998288T3 DK0998288T3 (da) 2002-10-14
DK0998288T4 true DK0998288T4 (da) 2005-08-22

Family

ID=21912426

Family Applications (2)

Application Number Title Priority Date Filing Date
DK98911614T DK0998288T4 (da) 1997-03-13 1998-03-12 Sammensætninger indeholdende kapasaicin eller kapsaicinanaloge og et lokalbedövelsesmiddel
DK01204692.6T DK1201241T3 (da) 1997-03-13 1998-03-12 Sammensætninger indeholdende capsaicin eller capsaicinanaloge og et bedøvelsesmiddel

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK01204692.6T DK1201241T3 (da) 1997-03-13 1998-03-12 Sammensætninger indeholdende capsaicin eller capsaicinanaloge og et bedøvelsesmiddel

Country Status (12)

Country Link
US (1) US5962532A (da)
EP (2) EP0998288B2 (da)
JP (1) JP2001515492A (da)
AT (2) ATE219674T1 (da)
AU (1) AU720859B2 (da)
CA (1) CA2285203C (da)
DE (2) DE69841907D1 (da)
DK (2) DK0998288T4 (da)
ES (2) ES2350755T3 (da)
HK (1) HK1027759A1 (da)
PT (2) PT1201241E (da)
WO (1) WO1998040070A1 (da)

Families Citing this family (66)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6248788B1 (en) 1996-11-06 2001-06-19 The Regents Of The University Of California Therapeutic method with capsaicin and capasicin analogs
US6239180B1 (en) 1995-11-08 2001-05-29 The Regents Of The University Of California Transdermal therapeutic device and method with capsaicin and capsaicin analogs
DK1014946T3 (da) 1997-09-18 2010-06-28 Pacira Pharmaceuticals Inc Liposomale anæstetiske sammensætninger med forsinket frigivelse
EP1030652B1 (en) 1997-11-14 2012-04-25 Pacira Pharmaceuticals, Inc. Production of multivesicular liposomes
SE9800139D0 (sv) 1998-01-21 1998-01-21 Astra Ab New use
US6790207B2 (en) 1998-06-04 2004-09-14 Curon Medical, Inc. Systems and methods for applying a selected treatment agent into contact with tissue to treat disorders of the gastrointestinal tract
US6802841B2 (en) 1998-06-04 2004-10-12 Curon Medical, Inc. Systems and methods for applying a selected treatment agent into contact with tissue to treat sphincter dysfunction
DE69940735D1 (de) 1998-07-17 2009-05-28 Pacira Pharmaceuticals Inc Biologisch abbaubare anordnungen zur kontrollierten freigabe eingeschlossener substanzen
US6723730B2 (en) * 2000-07-20 2004-04-20 Neurogen Corporation Capsaicin receptor ligands
US20040146590A1 (en) * 2001-03-22 2004-07-29 Iadarola Michael J Molecular neurochirurgie for pain control administering locally capsaicin or resinferatoxin
US20030096000A1 (en) * 2001-05-31 2003-05-22 Solis Rosa Maria Encapsulation of nanosuspensions in liposomes and microspheres
EP1414427A4 (en) * 2001-08-10 2004-08-18 Synta Pharmaceuticals Corp KAVALACTONE COMPOSITIONS AND METHODS OF USE
JP2005508372A (ja) * 2001-11-02 2005-03-31 エラン コーポレーシヨン ピーエルシー 薬剤組成物
KR20040085151A (ko) * 2002-01-17 2004-10-07 뉴로젠 코포레이션 캡사이신 조절자로서의 치환된 퀴나졸린-4-일 아민 유사체
EP1539124B1 (en) * 2002-09-05 2018-07-18 Vanderbilt Royalty Sub L.P. Compositions and kits for the removal of irritating compounds from bodily surfaces
CA2499994C (en) * 2002-09-23 2012-07-10 Verion, Inc. Abuse-resistant pharmaceutical compositions
WO2004056305A2 (en) * 2002-12-18 2004-07-08 Algorx Administration of capsaicinoids
JP2006513267A (ja) * 2002-12-18 2006-04-20 アルゴルクス ファーマスーティカルズ，インク カプサイシノイドの投与
US7943166B2 (en) 2003-04-10 2011-05-17 Neurogesx, Inc. Methods and compositions for administration of TRPV1 agonists
ES2542847T3 (es) 2004-06-02 2015-08-12 Neurogesx Inc. Formulaciones que comprenden capsaicina, un anestésico local y/o un agente antipruriginoso para el tratamiento del dolor
WO2006066419A1 (de) 2004-12-22 2006-06-29 Mestex Ag Mischung eines vanilloidrezeptoragonisten mit einer nervenregenerationshemmenden substanz, ihre verwendung für die herstellung eines schmerzmittels und verfahren zur applikation dieses mittels
EP1830835B1 (de) * 2004-12-28 2012-03-14 Mestex AG Verwendung eines vanilloidrezeptoragonisten zusammen mit einem glycosaminoglycan oder proteoglycan f]r die herstellung eines mittels zur behandlung von gelenkschmerzen und verfahren zur applikation dieses mittels
CA2594202C (en) 2004-12-28 2013-12-03 Mestex Ag Use of resiniferatoxin (rtx) for producing an agent for treating joint pains and method for applying said agent
ZA200707492B (en) * 2005-02-14 2009-02-25 Neurogesx Inc Device for delivery of TRPV1 agonists
US20060222690A1 (en) * 2005-03-30 2006-10-05 Bley Keith R Low-concentration capsaicin patch and methods for treating neuropathic pain
EA013056B1 (ru) * 2005-04-01 2010-02-26 Ньюроджесэкс, Инк. Масла капсаициноидов и способы их получения и применения
US8916611B2 (en) * 2006-04-28 2014-12-23 Warsaw Orthopedic, Inc. Pharmaceutical removal of neuronal extensions from a degenerating disc
US7943666B2 (en) * 2006-07-24 2011-05-17 Trinity Laboratories, Inc. Esters of capsaicin for treating pain
US7645767B2 (en) * 2006-08-31 2010-01-12 Trinity Laboratories, Inc. Pharmaceutical compositions for treating chronic pain and pain associated with neuropathy
KR101683042B1 (ko) 2008-04-04 2016-12-06 포사이트 비젼4, 인크. 통증 관리 및 시력을 위한 치료 장치
US8158682B2 (en) * 2008-09-12 2012-04-17 Vallinex, Inc. Instillation administration of capsaicinoids for the treatment of pain
US8987328B2 (en) * 2008-10-30 2015-03-24 Trinity Laboratories, Inc. Esters of capsaicinoids as dietary supplements
CA2761156C (en) * 2009-05-07 2017-03-14 University Of Cincinnati Methods of preventing ischemic injury using peripheral nociceptive stimulation
WO2011044381A1 (en) * 2009-10-07 2011-04-14 Inflasoothe, Inc. Pain relief composition, system and method
US8591025B1 (en) 2012-09-11 2013-11-26 Nexisvision, Inc. Eye covering and refractive correction methods for LASIK and other applications
WO2011050365A1 (en) 2009-10-23 2011-04-28 Forsight Labs, Llc Conformable therapeutic shield for vision and pain
WO2011050327A1 (en) 2009-10-23 2011-04-28 Forsight Labs Llc Corneal denervation for treatment of ocular pain
EP2629610B1 (en) 2010-07-27 2017-09-06 Flex Pharma, Inc. Methods and compositions for preventing and relieving muscle cramps and for recovery from neuromuscular irritability and fatigue following exercise
CA2816031A1 (en) 2010-10-25 2012-05-10 Nexisvision, Inc. Methods and apparatus to identify eye coverings for vision
CN103328038A (zh) 2010-12-01 2013-09-25 史拜诺莫度雷森公司 向神经解剖结构直接递送药剂
US8678584B2 (en) 2012-04-20 2014-03-25 Nexisvision, Inc. Contact lenses for refractive correction
KR20140023378A (ko) 2011-04-28 2014-02-26 넥시스비젼, 인코포레이티드 개선된 눈물 흐름, 편안함, 및/또는 이용성을 지니는 눈 보호 및 굴절 교정 방법 및 장치
BR112014005358A8 (pt) 2011-09-09 2017-10-03 Propella Therapeutics Inc Composições compreendendo agonista seletivo de trpv1 e seus usos
US9211274B2 (en) * 2012-02-01 2015-12-15 Warsaw Orthopedic, Inc. TRPV1 compounds in a biodegradable polymer carrier
US9465233B2 (en) 2012-04-20 2016-10-11 Nexisvision, Inc. Bimodular contact lenses
CN104335104B (zh) 2012-04-20 2017-06-09 内希斯视觉股份有限公司 用于屈光矫正的接触透镜
CA2891218A1 (en) 2012-11-12 2014-05-15 Api Genesis, Llc Aqueous based capsaicinoid formulations and methods of manufacture and use
JP6310072B2 (ja) 2013-06-26 2018-04-11 ネクシスビジョン， インコーポレイテッド 屈折矯正のためのコンタクトレンズ
US9956166B2 (en) 2013-09-18 2018-05-01 Sorrento Therapeutics, Inc. Methods for administration and methods for treating cardiovascular diseases with resiniferatoxin
US20150133561A1 (en) 2013-11-12 2015-05-14 Vizuri Health Sciences Llc Aqueous based capsaicinoid formulations and methods of manufacture and use
US9341864B2 (en) 2013-11-15 2016-05-17 Nexisvision, Inc. Contact lenses having a reinforcing scaffold
WO2015116559A1 (en) 2014-01-29 2015-08-06 Nexisvision, Inc. Multifocal bimodulus contact lenses
KR102073258B1 (ko) 2014-04-15 2020-02-04 비쭈리 헬스 사이언스 엘엘씨 통증 완화용 국소 조성물, 제조방법 및 용도
US11634384B2 (en) 2014-11-25 2023-04-25 Concentric Analgesics, Inc. Prodrugs of phenolic TRPV1 agonists
US9359316B1 (en) 2014-11-25 2016-06-07 Concentric Analgesics, Inc. Prodrugs of phenolic TRPV1 agonists
EP3463576A4 (en) 2016-05-25 2020-01-15 Concentric Analgesics, Inc. PRODRUGS BY PHENOLIC TRPV1 AGONISTS IN COMBINATION WITH LOCAL ANESTHETIC AND VASOCONSTRICTORS FOR IMPROVED LOCAL ANESTHESIA
EP3534961A4 (en) 2016-11-02 2020-05-27 Centrexion Therapeutics Corporation STABLE AQUEOUS INJECTABLE CAPSAICIN FORMULATIONS AND MEDICAL USES THEREOF
US11253493B2 (en) 2017-01-23 2022-02-22 Cliff-Cartwright Corporation Compositions and methods affecting exercise performance
CN111201015A (zh) 2017-07-20 2020-05-26 中枢疗法公司 使用辣椒素治疗疼痛的方法和组合物
US20210283098A1 (en) * 2018-07-05 2021-09-16 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Methods and Compositions for Treating Pain and Itch
US10717712B2 (en) 2018-07-27 2020-07-21 Concentric Analgesics, Inc. Pegylated prodrugs of phenolic TRPV1 agonists
US11254659B1 (en) 2019-01-18 2022-02-22 Centrexion Therapeutics Corporation Capsaicinoid prodrug compounds and their use in treating medical conditions
US11447444B1 (en) 2019-01-18 2022-09-20 Centrexion Therapeutics Corporation Capsaicinoid prodrug compounds and their use in treating medical conditions
US11278494B1 (en) 2021-01-22 2022-03-22 Pacira Pharmaceuticals, Inc. Manufacturing of bupivacaine multivesicular liposomes
US11033495B1 (en) 2021-01-22 2021-06-15 Pacira Pharmaceuticals, Inc. Manufacturing of bupivacaine multivesicular liposomes
US11357727B1 (en) 2021-01-22 2022-06-14 Pacira Pharmaceuticals, Inc. Manufacturing of bupivacaine multivesicular liposomes

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4313958A (en) * 1980-10-24 1982-02-02 The Procter & Gamble Company Method of producing analgesia
US4424205A (en) * 1982-03-18 1984-01-03 The Procter & Gamble Company Hydroxyphenylacetamides having analgesic and anti-irritant activity
US4681897A (en) * 1984-01-16 1987-07-21 The Procter & Gamble Company Pharmaceutical products providing enhanced analgesia
US4939149A (en) * 1988-10-24 1990-07-03 The United States Of America As Represented By The Department Of Health And Human Services Resiniferatoxin and analogues thereof to cause sensory afferent C-fiber and thermoregulatory desensitization
US4997853A (en) * 1988-12-02 1991-03-05 Galenpharma, Inc. Method and compositions utilizing capsaicin as an external analgesic
US5008289A (en) * 1988-12-02 1991-04-16 Galenpharma, Inc. Composition for treating nasal disorders and headaches
US5188837A (en) * 1989-11-13 1993-02-23 Nova Pharmaceutical Corporation Lipsopheres for controlled delivery of substances
US5762963A (en) * 1995-06-07 1998-06-09 Emory University Method and compositions for controlling oral and pharyngeal pain using capsaicinoids

Also Published As

Publication number Publication date
CA2285203C (en) 2005-07-26
AU720859B2 (en) 2000-06-15
US5962532A (en) 1999-10-05
EP0998288B2 (en) 2005-08-03
WO1998040070A1 (en) 1998-09-17
HK1027759A1 (en) 2001-01-23
PT1201241E (pt) 2010-12-02
EP1201241A3 (en) 2004-01-02
DK1201241T3 (da) 2010-12-13
ES2179473T5 (es) 2006-03-01
ATE481970T1 (de) 2010-10-15
DE69806246D1 (de) 2002-08-01
EP1201241B8 (en) 2010-10-27
ES2179473T3 (es) 2003-01-16
DE69806246T2 (de) 2003-02-06
AU6553298A (en) 1998-09-29
DK0998288T3 (da) 2002-10-14
EP1201241B1 (en) 2010-09-22
EP1201241A2 (en) 2002-05-02
CA2285203A1 (en) 1998-09-17
EP0998288B1 (en) 2002-06-26
PT998288E (pt) 2002-11-29
EP0998288A1 (en) 2000-05-10
ATE219674T1 (de) 2002-07-15
DE69841907D1 (de) 2010-11-04
DE69806246T3 (de) 2006-05-18
JP2001515492A (ja) 2001-09-18
ES2350755T3 (es) 2011-01-26

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