DK0946567T3 - New Camptothecin Analog Compounds, Their Use as Drugs and Pharmaceuticals Containing Them - Google Patents
New Camptothecin Analog Compounds, Their Use as Drugs and Pharmaceuticals Containing ThemInfo
- Publication number
- DK0946567T3 DK0946567T3 DK97950236T DK97950236T DK0946567T3 DK 0946567 T3 DK0946567 T3 DK 0946567T3 DK 97950236 T DK97950236 T DK 97950236T DK 97950236 T DK97950236 T DK 97950236T DK 0946567 T3 DK0946567 T3 DK 0946567T3
- Authority
- DK
- Denmark
- Prior art keywords
- drugs
- analog compounds
- pharmaceuticals containing
- camptothecin analog
- new camptothecin
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/14—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/06—Antimalarials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/61—Halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/64—One oxygen atom attached in position 2 or 6
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9615774A FR2757514B1 (en) | 1996-12-20 | 1996-12-20 | NOVEL CAMPTOTHECIN ANALOGS, PREPARATION METHODS, USE THEREOF AS MEDICAMENTS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM |
PCT/FR1997/002218 WO1998028305A1 (en) | 1996-12-20 | 1997-12-05 | Novel counterparts of camptothecin, their application as medicine and pharmaceutical compositions containing them |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0946567T3 true DK0946567T3 (en) | 2003-12-22 |
Family
ID=9498938
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK97950236T DK0946567T3 (en) | 1996-12-20 | 1997-12-05 | New Camptothecin Analog Compounds, Their Use as Drugs and Pharmaceuticals Containing Them |
Country Status (26)
Country | Link |
---|---|
EP (1) | EP0946567B1 (en) |
JP (2) | JP3576175B2 (en) |
KR (1) | KR100516874B1 (en) |
CN (1) | CN1097056C (en) |
AR (1) | AR008543A1 (en) |
AT (1) | ATE248177T1 (en) |
AU (1) | AU734485B2 (en) |
BR (1) | BR9714170A (en) |
CA (1) | CA2275351C (en) |
CZ (1) | CZ299795B6 (en) |
DE (1) | DE69724453T2 (en) |
DK (1) | DK0946567T3 (en) |
ES (1) | ES2206761T3 (en) |
FR (1) | FR2757514B1 (en) |
HK (1) | HK1024695A1 (en) |
HU (1) | HUP9904210A3 (en) |
MX (1) | MXPA99005776A (en) |
MY (1) | MY119473A (en) |
NO (1) | NO326464B1 (en) |
NZ (1) | NZ335939A (en) |
PL (1) | PL188181B1 (en) |
PT (1) | PT946567E (en) |
RU (1) | RU2194051C2 (en) |
UA (1) | UA57758C2 (en) |
WO (1) | WO1998028305A1 (en) |
ZA (1) | ZA9711129B (en) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2790261B1 (en) * | 1999-02-26 | 2004-09-10 | Sod Conseils Rech Applic | NOVEL OPTICALLY PURE CAMPTOTHECIN ANALOGS AND PROCESSES FOR THEIR PREPARATION |
US6291676B1 (en) * | 1999-03-03 | 2001-09-18 | University Of Kentucky Research Foundation | Water-soluble derivatives of camptothecin/homocamptothecin |
US6207832B1 (en) * | 1999-04-09 | 2001-03-27 | University Of Pittsburgh | Camptothecin analogs and methods of preparation thereof |
AU3455100A (en) * | 1999-05-28 | 2000-12-18 | Nippon Chemiphar Co. Ltd. | Process for the preparation of 2-halo-3-(3-quinolyl)propionic acid derivatives |
US6372906B1 (en) | 2001-04-12 | 2002-04-16 | University Of Pittsburgh | Synthesis of silyl camptothecins and silyl homocamptothecins |
US6723853B2 (en) | 2001-08-27 | 2004-04-20 | University Of Pittsburgh | Intermediates and methods of preparation of intermediates in the enantiomeric synthesis of (20R)homocamptothecins and the enantiomeric synthesis of (20R)homocamptothecins |
AU2003225642A1 (en) * | 2002-03-01 | 2003-09-16 | Fluorous Techonologies Inc | Mappicine analogs, intermediates in the synthesis of mappicine analogs and methods of synthesis of mappicine analogs |
ITRM20040288A1 (en) * | 2004-06-11 | 2004-09-11 | Sigma Tau Ind Farmaceuti | USE OF 7-T-BUTOXYIMINOMETHYL CAMPTOTECIN FOR THE PREPARATION OF A MEDICATION FOR THE TREATMENT OF UTERUS NEOPLASIES. |
CA2580747A1 (en) * | 2004-09-21 | 2006-03-30 | Societe De Conseils De Recherches Et D'applications Scientifiques (S.C.R .A.S.) | Novel processes for the production of useful intermediates |
CN102746314B (en) * | 2011-04-18 | 2016-07-06 | 华东师范大学 | Containing stablizing the camptothecine compounds of 7 yuan of lactonic rings, preparation method and purposes |
WO2023232145A1 (en) * | 2022-06-02 | 2023-12-07 | 华东师范大学 | Small molecule of homocamptothecins and use thereof |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5391745A (en) * | 1992-07-23 | 1995-02-21 | Sloan-Kettering Institute For Cancer Research | Methods of preparation of camptothecin analogs |
DK0835258T3 (en) * | 1995-06-21 | 2003-02-03 | Sod Conseils Rech Applic | New Camptothecin Analogs, Methods of Preparation thereof, Their Use as Medicines and Pharmaceutical Preparations Containing These |
-
1996
- 1996-12-20 FR FR9615774A patent/FR2757514B1/en not_active Expired - Fee Related
-
1997
- 1997-05-12 UA UA99063449A patent/UA57758C2/en unknown
- 1997-12-05 EP EP97950236A patent/EP0946567B1/en not_active Expired - Lifetime
- 1997-12-05 ES ES97950236T patent/ES2206761T3/en not_active Expired - Lifetime
- 1997-12-05 AU AU53265/98A patent/AU734485B2/en not_active Ceased
- 1997-12-05 DK DK97950236T patent/DK0946567T3/en active
- 1997-12-05 NZ NZ335939A patent/NZ335939A/en not_active IP Right Cessation
- 1997-12-05 JP JP52844898A patent/JP3576175B2/en not_active Expired - Fee Related
- 1997-12-05 PT PT97950236T patent/PT946567E/en unknown
- 1997-12-05 MX MXPA99005776A patent/MXPA99005776A/en not_active IP Right Cessation
- 1997-12-05 CZ CZ0220599A patent/CZ299795B6/en not_active IP Right Cessation
- 1997-12-05 CA CA002275351A patent/CA2275351C/en not_active Expired - Fee Related
- 1997-12-05 AT AT97950236T patent/ATE248177T1/en active
- 1997-12-05 PL PL97334125A patent/PL188181B1/en not_active IP Right Cessation
- 1997-12-05 RU RU99115829/04A patent/RU2194051C2/en not_active IP Right Cessation
- 1997-12-05 BR BR9714170-4A patent/BR9714170A/en not_active Application Discontinuation
- 1997-12-05 KR KR10-1999-7005603A patent/KR100516874B1/en not_active IP Right Cessation
- 1997-12-05 CN CN97180815A patent/CN1097056C/en not_active Expired - Fee Related
- 1997-12-05 WO PCT/FR1997/002218 patent/WO1998028305A1/en active IP Right Grant
- 1997-12-05 DE DE69724453T patent/DE69724453T2/en not_active Expired - Lifetime
- 1997-12-05 HU HU9904210A patent/HUP9904210A3/en unknown
- 1997-12-10 ZA ZA9711129A patent/ZA9711129B/en unknown
- 1997-12-17 MY MYPI97006088A patent/MY119473A/en unknown
- 1997-12-19 AR ARP970106043A patent/AR008543A1/en active IP Right Grant
-
1999
- 1999-06-18 NO NO19992998A patent/NO326464B1/en not_active IP Right Cessation
-
2000
- 2000-07-04 HK HK00104036A patent/HK1024695A1/en not_active IP Right Cessation
-
2003
- 2003-11-26 JP JP2003395513A patent/JP2004115535A/en not_active Withdrawn
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